J P Gisbert

Summary

Country: Spain

Publications

  1. doi Comparative effectiveness of azathioprine in Crohn's disease and ulcerative colitis: prospective, long-term, follow-up study of 394 patients
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
    Aliment Pharmacol Ther 28:228-38. 2008
  2. ncbi H. pylori eradication therapy vs. antisecretory non-eradication therapy (with or without long-term maintenance antisecretory therapy) for the prevention of recurrent bleeding from peptic ulcer
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa Universidad Autónoma de Madrid, Diego de Leon, 62, Madrid, Spain, 28006
    Cochrane Database Syst Rev . 2003
  3. ncbi Treatment of Helicobacter pylori Eradication Failures
    Javier P Gisbert
    Gastroenterology Unit, La Princesa University Hospital, Playa de Mojácar 29, 28669 Boadilla del Monte, Madrid, Spain
    Curr Treat Options Gastroenterol 6:147-156. 2003
  4. ncbi [Common errors in the management of the seriously ill patient with inflammatory bowel disease]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Spain
    Gastroenterol Hepatol 30:294-314. 2007
  5. doi Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
    Inflamm Bowel Dis 16:881-95. 2010
  6. ncbi [Questions and answers on the role of azathioprine and 6-mercaptopurine in the treatment of inflammatory bowel disease]
    J P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
    Gastroenterol Hepatol 25:401-15. 2002
  7. ncbi [Pharmacological treatment of bleeding peptic ulcer]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, 28669 Boadilla del Monte, Madrid, Spain
    Med Clin (Barc) 127:66-75. 2006
  8. ncbi Potent gastric acid inhibition in Helicobacter pylori eradication
    Javier P Gisbert
    Gastroenterology Service, La Princesa University Hospital, Madrid, Spain
    Drugs 65:83-96. 2005
  9. ncbi Recurrence of Helicobacter pylori infection after several eradication therapies: long-term follow-up of 1000 patients
    J P Gisbert
    Gastroenterology Units of La Princesa University Hospital, Madrid, Spain
    Aliment Pharmacol Ther 23:713-9. 2006
  10. doi [Rescue therapy after Helicobacter pylori eradication failure]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Espana
    Gastroenterol Hepatol 34:89-99. 2011

Detail Information

Publications162 found, 100 shown here

  1. doi Comparative effectiveness of azathioprine in Crohn's disease and ulcerative colitis: prospective, long-term, follow-up study of 394 patients
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
    Aliment Pharmacol Ther 28:228-38. 2008
    ..The long-term efficiacy for thiopurinic drugs in Crohn's disease (CD), and particularly in ulcerative colitis (UC), has been insufficiently studied...
  2. ncbi H. pylori eradication therapy vs. antisecretory non-eradication therapy (with or without long-term maintenance antisecretory therapy) for the prevention of recurrent bleeding from peptic ulcer
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa Universidad Autónoma de Madrid, Diego de Leon, 62, Madrid, Spain, 28006
    Cochrane Database Syst Rev . 2003
    ..On the other hand, the precise efficacy of H. pylori eradication for the prevention of rebleeding from peptic ulcer is unknown...
  3. ncbi Treatment of Helicobacter pylori Eradication Failures
    Javier P Gisbert
    Gastroenterology Unit, La Princesa University Hospital, Playa de Mojácar 29, 28669 Boadilla del Monte, Madrid, Spain
    Curr Treat Options Gastroenterol 6:147-156. 2003
    ..Recently, rifabutin-based rescue therapies have been shown to constitute an encouraging strategy for eradication failures because they are effective for H. pylori strains resistant to antibiotics...
  4. ncbi [Common errors in the management of the seriously ill patient with inflammatory bowel disease]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Spain
    Gastroenterol Hepatol 30:294-314. 2007
  5. doi Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
    Inflamm Bowel Dis 16:881-95. 2010
    ..The use of infliximab is probably compatible with breast-feeding...
  6. ncbi [Questions and answers on the role of azathioprine and 6-mercaptopurine in the treatment of inflammatory bowel disease]
    J P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
    Gastroenterol Hepatol 25:401-15. 2002
  7. ncbi [Pharmacological treatment of bleeding peptic ulcer]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, 28669 Boadilla del Monte, Madrid, Spain
    Med Clin (Barc) 127:66-75. 2006
  8. ncbi Potent gastric acid inhibition in Helicobacter pylori eradication
    Javier P Gisbert
    Gastroenterology Service, La Princesa University Hospital, Madrid, Spain
    Drugs 65:83-96. 2005
    ..pylori infection. However, all PPIs (omeprazole, lansoprazole, pantoprazole, rabeprazole, and esomeprazole) are equivalent when given together with two antibiotics to cure the infection...
  9. ncbi Recurrence of Helicobacter pylori infection after several eradication therapies: long-term follow-up of 1000 patients
    J P Gisbert
    Gastroenterology Units of La Princesa University Hospital, Madrid, Spain
    Aliment Pharmacol Ther 23:713-9. 2006
    ..To study the incidence of Helicobacter pylori recurrence, its chronological aspects, and the variables that might influence it...
  10. doi [Rescue therapy after Helicobacter pylori eradication failure]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Espana
    Gastroenterol Hepatol 34:89-99. 2011
    ..Finally, rifabutin-based therapies have achieved promising results and are even effective in patients with multiple failures or multiple antibiotic resistance...
  11. doi The sequential therapy regimen for Helicobacter pylori eradication
    Javier P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, 62 Diego de Leon, 28006 Madrid, Spain
    Expert Opin Pharmacother 11:905-18. 2010
    ..Standard triple therapy (STT) is the most used treatment for Helicobater pylori infection. The prevalence of antibiotic resistance has increased substantially in recent years and there has been a corresponding decrease in efficacy...
  12. ncbi Helicobacter pylori and bleeding duodenal ulcer: prevalence of the infection and role of non-steroidal anti-inflammatory drugs
    J P Gisbert
    Dept of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Scand J Gastroenterol 36:717-24. 2001
    ..Our aim was to study the prevalence of H. pylori in bleeding duodenal ulcer (DU), with both invasive and non-invasive methods, and to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs)...
  13. ncbi [Treatment of alcoholic hepatitis with corticosteroids. Are they really effective?]
    Javier P Gisbert
    Servicio de Gastroenterología y Hepatología Hospital Universtiario de la Princesa Madrid España
    Med Clin (Barc) 119:590-5. 2002
  14. ncbi [Treatment of stenosis due to Crohn's disease]
    J P Gisbert
    Servicio de Aparato Digestivo Hospital Universitario de La Princesa Madrid Spain
    Gastroenterol Hepatol 25:560-9. 2002
  15. ncbi [Thiopurine methyltransferase activity in patients with autoimmune hepatitis]
    Javier P Gisbert
    Servicio de Gastroenterología y Hepatología Hospital Universitario de la Princesa Universidad Autónoma Madrid Spain
    Med Clin (Barc) 121:481-4. 2003
    ..Our objective was to analyze the activity of TPMT in a group of 200 patients with autoimmune hepatitis and to evaluate the possible effect of some variables such as the treatment with azathioprine on this activity...
  16. ncbi One-week therapy with pantoprazole versus ranitidine bismuth citrate plus two antibiotics for Helicobacter pylori eradication
    J P Gisbert
    Department of Gastroenterology, Hospital de la Princessa, Universidad Autonoma de Madrid, Spain
    Eur J Gastroenterol Hepatol 12:489-95. 2000
    ..Our aim was to evaluate and to compare these two novel short-term triple therapies (Pan+Amo+Cla and RBC+Amo+Cla) for treatment of Helicobacter pylori...
  17. ncbi Helicobacter pylori and gastroesophageal reflux disease: lack of influence of infection on twenty-four-hour esophageal pH monitoring and endoscopic findings
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    J Clin Gastroenterol 32:210-4. 2001
    ..14 +/- 12 mmHg) among H. pylori-positive and -negative patients. H. pylori infection is not associated with gastroesophageal reflux disease, as evaluated endoscopically and with 24-hour esophageal pH monitoring...
  18. ncbi Helicobacter pylori therapy: first-line options and rescue regimen
    J P Gisbert
    Department of Gastroenterology, University Hospital La Princesa, Madrid, Spain
    Dig Dis 19:134-43. 2001
    ....
  19. ncbi Systematic review: Rabeprazole-based therapies in Helicobacter pylori eradication
    J P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
    Aliment Pharmacol Ther 17:751-64. 2003
    ....
  20. ncbi Meta-analysis: proton pump inhibitors vs. H2-receptor antagonists--their efficacy with antibiotics in Helicobacter pylori eradication
    J P Gisbert
    Department of Gastroenterology, University Hospital, Madrid, Spain
    Aliment Pharmacol Ther 18:757-66. 2003
    ..It is unknown whether proton pump inhibitors are superior to H2-receptor antagonists in Helicobacter pylori eradication regimens...
  21. ncbi Prevalence of hepatitis C virus infection in B-cell non-Hodgkin's lymphoma: systematic review and meta-analysis
    Javier P Gisbert
    Gastroenterology and Hepatology Service, La Princesa University Hospital, Madrid, Spain
    Gastroenterology 125:1723-32. 2003
    ....
  22. ncbi Empirical Helicobacter pylori "rescue" therapy after failure of two eradication treatments
    J P Gisbert
    Department of Gastroenterology, La Princesa University Hospital, Madrid, Spain
    Dig Liver Dis 36:7-12. 2004
    ..pylori in approximately 20-30% of the cases. Our aim was to evaluate the efficacy of different rescue therapies prescribed to patients in whom two consecutive H. pylori eradication regimens had failed...
  23. ncbi [Indications and consequences of Helicobacter pylori eradication on gastroesophageal reflux disease]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Espana
    Med Clin (Barc) 124:697-709. 2005
    ..In the meantime, as it occurs with any controversial indication, the decision of the doctor facing a patient infected by H. pylori and needing maintenance therapy with PPIs should be assessed on a case by case basis...
  24. ncbi Systematic review and meta-analysis: proton pump inhibitor vs. ranitidine bismuth citrate plus two antibiotics in Helicobacter pylori eradication
    Javier P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Helicobacter 10:157-71. 2005
    ..RBC with two antibiotics for 1 week...
  25. ncbi [Breath tests in the diagnosis of gastrointestinal diseases]
    J P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Espana
    Gastroenterol Hepatol 28:407-16. 2005
    ....
  26. ncbi Evaluation of 3 different tests for the detection of stool antigens to confirm Helicobacter pylori eradication after treatment. A pilot study
    J P Gisbert
    Servicio de Gastroenterologia, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Madrid, Spain
    Gastroenterol Hepatol 28:615-8. 2005
    ..Recently, several new diagnostic methods aimed to detect Helicobacter pylori stool antigens have been developed. Our aim was to evaluate the accuracy of 3 different stool tests to confirm H. pylori eradication...
  27. ncbi Choice of azathioprine or 6-mercaptopurine dose based on thiopurine methyltransferase (TPMT) activity to avoid myelosuppression. A prospective study
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Spain
    Hepatogastroenterology 53:399-404. 2006
    ..To prospectively evaluate whether, in patients with inflammatory bowel disease, the choice of azathioprine (AZA) or 6-mercaptopurine (6-MP) dose based on thiopurine methyltransferase (TPMT) activity prevents myelotoxicity...
  28. ncbi Third-line rescue therapy with levofloxacin is more effective than rifabutin rescue regimen after two Helicobacter pylori treatment failures
    J P Gisbert
    Department of Gastroenterology, La Princesa University Hospital, Universidad Autonoma, Madrid, Spain
    Aliment Pharmacol Ther 24:1469-74. 2006
    ..In patients with a first eradication failure, a second (rescue) therapy still fails in > 20% of cases...
  29. ncbi Gastric MALT lymphoma: clinical characteristics and prevalence of H. pylori infection in a series of 37 cases
    J P Gisbert
    Servides of Gastroenterology, Hospital Universitario de La Princesa Universidad Autónoma Madrid, Spain
    Rev Esp Enferm Dig 98:655-65. 2006
    ..to perform a retrospective review of the clinical characteristics and prevalence of H. pylori infection in patients with gastric MALT lymphoma diagnosed in our hospital during the last 15 years...
  30. ncbi 13C-urea breath test during hospitalization for the diagnosis of Helicobacter pylori infection in peptic ulcer bleeding
    Javier P Gisbert
    Service of Gastroenterology and Hepatology, La Princesa University Hospital, Universidad Autonoma, Madrid, Spain
    Helicobacter 12:231-7. 2007
    ..To evaluate the accuracy of (13)C-urea breath test (UBT) to detect Helicobacter pylori infection in patients hospitalized with peptic ulcer bleeding and treated with proton pump inhibitors (PPIs)...
  31. ncbi [Common errors in the management of outpatients with inflammatory bowel disease]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Espana
    Gastroenterol Hepatol 30:469-86. 2007
  32. doi Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review
    Javier P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Madrid, Spain
    Am J Gastroenterol 104:760-7. 2009
    ..To review the frequency with which infliximabloses its effect and dose "intensification" is required for Crohn's disease treatment...
  33. doi Oral and intravenous iron treatment in inflammatory bowel disease: hematological response and quality of life improvement
    Javier P Gisbert
    Hospital Universitario de la Princesa, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Madrid, Spain
    Inflamm Bowel Dis 15:1485-91. 2009
    ..The aim was to evaluate the efficacy and tolerance of oral and intravenous iron treatment in anemic inflammatory bowel disease (IBD) patients, considering both hematological and quality-of-life outcomes...
  34. doi Second-line rescue triple therapy with levofloxacin after failure of non-bismuth quadruple "sequential" or "concomitant" treatment to eradicate H. pylori infection
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Instituto de Investigación Sanitaria Princesa IP, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Madrid, Spain
    Scand J Gastroenterol 48:652-6. 2013
    ..Eradication with rescue regimens may be challenging after failure of key antibiotics such as clarithromycin and nitroimidazoles...
  35. ncbi Value of quantitative serology for confirmation of Helicobacter pylori eradication: an 18-month follow-up study
    J P Gisbert
    Department of Gastroenterology, Hospital de la Princesa, Universidad Autonoma, Madrid, Spain
    Clin Infect Dis 30:976-80. 2000
    ..5 months after antibiotic therapy is completed) can be used as a noninvasive, simple, and inexpensive method to confirm H. pylori eradication...
  36. ncbi 13C-urea breath test for the diagnosis of Helicobacter pylori infection before treatment: is citric acid necessary?
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Dig Liver Dis 32:20-4. 2000
    ..Thus, our aim was to compare 13C-urea breath test with and without citric acid solution, to evaluate whether 13C-urea breath test can also achieve favourable results when the test meal is omitted...
  37. ncbi Proton pump inhibitor, clarithromycin and either amoxycillin or nitroimidazole: a meta-analysis of eradication of Helicobacter pylori
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Aliment Pharmacol Ther 14:1319-28. 2000
    ..those using proton pump inhibitor, clarithromycin and a nitroimidazole (N) (PCN) for H. pylori eradication...
  38. ncbi Helicobacter pylori "test-and-scope" strategy for dyspeptic patients. Is it useful and safe?
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Dig Liver Dis 33:539-45. 2001
    ..To evaluate outcome of test-and-scope strategy using 13C-urea breath test, Helicobacter pylori IgG serology, and CagA serology...
  39. ncbi [Stool antigen test for initial Helicobacter pylori diagnosis and for confirmation of eradication after therapy]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa Madrid Spain
    Med Clin (Barc) 118:401-4. 2002
    ..Our aim was to prospectively evaluate the accuracy of HpSA both in the initial diagnosis of H. pylori infection and in the confirmation of the eradication after treatment...
  40. ncbi [Helicobacter pylori infection and functional dyspepsia. Meta-analysis of efficacy of eradication therapy]
    Javier P Gisbert
    Servicio de Aparato Digestivo Hospital Universitario de La Princesa Madrid Spain
    Med Clin (Barc) 118:405-9. 2002
    ..Our aim was to perform a meta-analysis of randomized studies comparing, in functional dyspepsia, the efficacy of H. pylori eradication treatment with that of treatments with no effect on H. pylori infection...
  41. ncbi Review article: Helicobacter pylori infection and gastric outlet obstruction - prevalence of the infection and role of antimicrobial treatment
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Aliment Pharmacol Ther 16:1203-8. 2002
    ..pylori-positive stenosis, whereas dilation or surgery should be reserved for patients who do not respond to such medical therapy...
  42. ncbi Meta-analysis: Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Spain
    Aliment Pharmacol Ther 19:617-29. 2004
    ..To perform a meta-analysis comparing the efficacy of Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer...
  43. ncbi The prevalence of hepatitis C virus infection in patients with non-Hodgkin's lymphoma
    Javier P Gisbert
    Gastroenterology and Hepatology Service, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Spain
    Eur J Gastroenterol Hepatol 16:135-8. 2004
    ..The aim of the present study was to assess the prevalence of hepatitis C virus (HCV) infection among patients with non-Hodgkin's lymphoma (NHL), and to compare it with that of a control group of voluntary blood donors...
  44. ncbi Evaluation of three different tests for the detection of stool antigens to diagnose Helicobacter pylori infection in patients with upper gastrointestinal bleeding
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Spain
    Aliment Pharmacol Ther 19:923-9. 2004
    ..To evaluate the accuracy of several methods aimed to detect Helicobacter pylori stool antigens in patients with upper gastrointestinal bleeding...
  45. ncbi Hepatocellular carcinoma risk in patients with porphyria cutanea tarda
    Javier P Gisbert
    Gastroenterology and Hepatology Service, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Spain
    Eur J Gastroenterol Hepatol 16:689-92. 2004
    ..The aim of our study was to evaluate the incidence of HCC in patients with PCT, and to assess the possible co-factors associated with cancer development...
  46. ncbi Stool antigen test for the diagnosis of Helicobacter pylori infection: a systematic review
    Javier P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Helicobacter 9:347-68. 2004
    ..Sensitivity and/or specificity in patients with gastrointestinal bleeding may be suboptimal. The stool antigen test performs well in children. Finally, the stool antigen test seems to be a cost-effective method...
  47. ncbi Review article: 13C-urea breath test in the diagnosis of Helicobacter pylori infection -- a critical review
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Aliment Pharmacol Ther 20:1001-17. 2004
    ....
  48. ncbi Systematic review: regression of lymphoproliferative disorders after treatment for hepatitis C infection
    J P Gisbert
    Gastroenterology and Hepatology Service, La Princesa University Hospital, 28006 Madrid, Spain
    Aliment Pharmacol Ther 21:653-62. 2005
    ....
  49. ncbi [Thiopurine methyltransferase activity in inflammatory bowel disease. A study on 7046 Spanish patients]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Spain
    Med Clin (Barc) 125:281-5. 2005
    ....
  50. ncbi How effective are rescue H. pylori eradication therapies in patients with dyspepsia?
    Javier P Gisbert
    Gastroenterololgy Unit, La Princesa University Hospital, Madrid, Spain
    Nat Clin Pract Gastroenterol Hepatol 2:180-1. 2005
  51. ncbi Long-term follow-up of 13C-urea breath test results after Helicobacter pylori eradication: frequency and significance of borderline delta13CO2 values
    J P Gisbert
    Gastroenterology Unit, La Princesa University Hospital, Autonomous University, Madrid, Spain
    Aliment Pharmacol Ther 23:275-80. 2006
    ..The precise choice of cut-off point for the 13C-urea breath test to define whether it is positive or negative represents a controversial issue...
  52. ncbi Levofloxacin- vs. ranitidine bismuth citrate-containing therapy after H. pylori treatment failure
    Javier P Gisbert
    Department of Gastroenterology, La Princesa University Hospital, Universidad Autonoma, Madrid, Spain
    Helicobacter 12:68-73. 2007
    ..Our aim was to compare two 7-day triple second-line regimens containing ranitidine bismuth citrate or levofloxacin...
  53. ncbi 5-Aminosalicylates and renal function in inflammatory bowel disease: a systematic review
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Spain
    Inflamm Bowel Dis 13:629-38. 2007
    ..The optimal monitoring schedule of serum creatinine in patients receiving 5-ASA treatment remains to be established, as there is no evidence to date that either the test, or the frequency of testing, improves patient outcomes...
  54. ncbi Thiopurine methyltransferase activity in Spain: a study of 14,545 patients
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Universidad Autonoma, Playa de Mojácar 29, Urb, Bonanza, 28669, Boadilla del Monte, Madrid, Spain
    Dig Dis Sci 52:1262-9. 2007
    ....
  55. ncbi Liver injury in inflammatory bowel disease: long-term follow-up study of 786 patients
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Spain
    Inflamm Bowel Dis 13:1106-14. 2007
    ....
  56. ncbi First-line triple therapy with levofloxacin for Helicobacter pylori eradication
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Madrid, Spain
    Aliment Pharmacol Ther 26:495-500. 2007
    ..At present, the efficacy of proton pump inhibitor-clarithromycin-amoxicillin regimen is relatively low...
  57. ncbi [How can we find, design, evaluate and use clinical practice guidelines?]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
    Gastroenterol Hepatol 31:239-57. 2008
  58. doi Questions and answers on the role of faecal calprotectin as a biological marker in inflammatory bowel disease
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain
    Dig Liver Dis 41:56-66. 2009
    ..Greater faecal calprotectin concentration has been shown in asymptomatic first-degree relatives of patients with inflammatory bowel disease, suggesting that there is a high prevalence of subclinical intestinal inflammation in them...
  59. ncbi Effect of 5-aminosalicylates on renal function in patients with inflammatory bowel disease: 4-year follow-up study
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain
    Gastroenterol Hepatol 31:477-84. 2008
    ..Our aim was to conduct a retrospective study of IBD patients, both with and without 5-ASA treatment, who underwent regular evaluation of renal function over a 4-year period...
  60. doi Review article: Helicobacter pylori-negative duodenal ulcer disease
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD m, Madrid, Spain
    Aliment Pharmacol Ther 30:791-815. 2009
    ..Helicobacter pylori infection rates in duodenal ulcer (DU) patients may be lower than previously estimated...
  61. doi Review article: non-bismuth quadruple (concomitant) therapy for eradication of Helicobater pylori
    J P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP, and Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas CIBERehd, Madrid, Spain
    Aliment Pharmacol Ther 34:604-17. 2011
    ..Traditional standard triple therapy for Helicobacter pylori infection (PPI-clarithromycin-amoxicillin) can easily be converted to non-bismuth quadruple (concomitant) therapy by the addition of a nitroimidazole twice daily...
  62. doi Review article: rifabutin in the treatment of refractory Helicobacter pylori infection
    J P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
    Aliment Pharmacol Ther 35:209-21. 2012
    ..Even with the current most effective treatment regimens, a relevant proportion of patients will fail to eradicate Helicobacter pylori infection...
  63. doi Fourth-line rescue therapy with rifabutin in patients with three Helicobacter pylori eradication failures
    J P Gisbert
    Gastroenterology Department, Hospital de la Princesa, Madrid, Spain
    Aliment Pharmacol Ther 35:941-7. 2012
    ..In some cases, Helicobacter pylori infection persists even after three eradication treatments...
  64. doi Comparison of the effectiveness of two protocols for vaccination (standard and double dosage) against hepatitis B virus in patients with inflammatory bowel disease
    J P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
    Aliment Pharmacol Ther 35:1379-85. 2012
    ..The response rate to hepatitis B virus (HBV) vaccination in patients with inflammatory bowel disease (IBD) is low...
  65. doi Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients
    Javier P Gisbert
    Gastroenterology Unit, La Princesa, Instituto de Investigación Sanitaria Princesa IP y, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Madrid, Spain
    J Clin Gastroenterol 47:130-5. 2013
    ..Second-line bismuth-containing quadruple therapy is complex and frequently induces adverse effects. A triple rescue regimen containing levofloxacin is a potential alternative; however, resistance to quinolones is rapidly increasing...
  66. doi Efficacy of hepatitis B vaccination and revaccination and factors impacting on response in patients with inflammatory bowel disease
    J P Gisbert
    Department of Gastroenterology and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
    Am J Gastroenterol 107:1460-6. 2012
    ....
  67. doi Kinetics of anti-hepatitis B surface antigen titers after hepatitis B vaccination in patients with inflammatory bowel disease
    Javier P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
    Inflamm Bowel Dis 19:554-8. 2013
    ....
  68. pmc Update on non-bismuth quadruple (concomitant) therapy for eradication of Helicobacter pylori
    Javier P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP, and Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas CIBERehd, Madrid, Spain
    Clin Exp Gastroenterol 5:23-34. 2012
    ..pylori) infection (proton pump inhibitor-clarithromycin-amoxicillin) can easily be converted to non-bismuth quadruple (concomitant) therapy by the addition of a nitroimidazole twice daily...
  69. pmc Rescue Therapy for Helicobacter pylori Infection 2012
    Javier P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP, and Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas CIBERehd, 28006 Madrid, Spain
    Gastroenterol Res Pract 2012:974594. 2012
    ..Even after two consecutive failures, several studies have demonstrated that H. pylori eradication can finally be achieved in almost all patients if several "rescue" therapies are consecutively given...
  70. pmc Helicobacter Pylori "Test-and-Treat" Strategy for Management of Dyspepsia: A Comprehensive Review
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain
    Clin Transl Gastroenterol 4:e32. 2013
    ..The aim present article addresses the test-and-treat strategy and attempts to provide practical conclusions for the clinician who diagnoses and treats patients with dyspepsia...
  71. doi Third-line rescue therapy with bismuth-containing quadruple regimen after failure of two treatments (with clarithromycin and levofloxacin) for H. pylori infection
    J P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Instituto de Investigación Sanitaria Princesa IP, Playa de Mojácar 29 Urb Bonanza, 28669, Boadilla del Monte, Madrid, Spain
    Dig Dis Sci 59:383-9. 2014
    ..Helicobacter pylori eradication therapy with a proton pump inhibitor (PPI), clarithromycin, and amoxicillin fails in >20 % of cases. A rescue therapy with PPI-amoxicillin-levofloxacin still fails in >20 % of patients...
  72. doi Safety of anti-TNF agents during pregnancy and breastfeeding in women with inflammatory bowel disease
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Instituto de Investigación Sanitaria Princesa IP, Madrid, Spain
    Am J Gastroenterol 108:1426-38. 2013
    ..However, data regarding their safety during pregnancy and breastfeeding are scarce. The aim of this study was to critically review available data on the safety of anti-TNF therapy during pregnancy and breastfeeding in women with IBD...
  73. doi Vaccination strategies in patients with IBD
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Diego de Leon 62, Madrid 28006, Spain
    Nat Rev Gastroenterol Hepatol 10:277-85. 2013
    ..Therefore, vaccination status should be checked and updated upon diagnosis of IBD...
  74. ncbi Pathophysiological bases of eosinophilic esophagitis therapy
    Ricardo Moreno-Borque
    Alergología Clínica Servicio de Medicina Interna, Hospital Rey Juan Carlos I, Mostoles, Madrid, Spain
    Inflamm Allergy Drug Targets 12:46-53. 2013
    ..Prolonged treatment is advised for EoE because it recurs frequently, particularly on discontinuation of therapy. Experimental treatments using immunotherapy are being investigated, but their safety and efficacy are yet to be defined...
  75. doi Long-term follow-up of 1,000 patients cured of Helicobacter pylori infection following an episode of peptic ulcer bleeding
    J P Gisbert
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
    Am J Gastroenterol 107:1197-204. 2012
    ..To evaluate the effect of Helicobacter pylori (H. pylori) eradication on ulcer bleeding recurrence in a prospective, long-term study including 1,000 patients...
  76. doi [Helicobacter pylori-related diseases]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP, Madrid, Spain
    Gastroenterol Hepatol 35:12-25. 2012
    ..Even after three eradication therapies have failed, an empirical rescue therapy (with rifabutin) can be effective. H. pylori reinfection is highly frequent in developing countries, probably due to intrafamilial transmission...
  77. doi [Helicobacter pylori-related diseases: dyspepsia, ulcers and gastric cancer]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de Princesa, Instituto de Investigación Sanitaria Princesa IP, Madrid, Espana
    Gastroenterol Hepatol 34:15-26. 2011
    ..Even after three previous H. pylori eradication failures, an empirical fourth-line rescue treatment with rifabutin may be effective...
  78. doi Review article: the effectiveness of standard triple therapy for Helicobacter pylori has not changed over the last decade, but it is not good enough
    J P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP y Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain
    Aliment Pharmacol Ther 34:1255-68. 2011
    ..Therefore, it is evident that new strategies to improve first-line treatment are urgently needed...
  79. ncbi [Helicobacter pylori and digestive hemorrhage due to duodenal ulcer: the prevalence of the infection, the efficacy of 3 triple therapies and the role of eradication in preventing a hemorrhagic recurrence]
    J P Gisbert
    Servicio de Gastroenterologia, Hospital Ramon y Cajal, Departamento de Medicina, Universidad de Alcala de Henares, Madrid
    Med Clin (Barc) 112:161-5. 1999
    ..To evaluate the efficacy on H. pylori eradication and on ulcer healing of three one-week triple therapies and to compare their efficacy with that of a dual therapy...
  80. ncbi Basal and stimulated gastrin and pepsinogen levels after eradication of Helicobacter pylori: a 1-year follow-up study
    J P Gisbert
    Department of Gastroenterology, Ramon y Cajal Hospital, University of Alcala de Henares, Madrid, Spain
    Eur J Gastroenterol Hepatol 11:189-200. 1999
    ..Finally, an evaluation was made of the variables influencing gastrin and PG concentration, with particular attention to H. pylori infection and histological lesions of gastric mucosa...
  81. ncbi [Antral biopsy is sufficient to confirm Helicobacter pylori eradication with the "new" one-week long triple treatments]
    J P Gisbert
    Hospital Ramon y Cajal, Departamento de Medicina, Universidad de Alcala de Henares, Madrid
    Med Clin (Barc) 112:365-7. 1999
    ..To evaluate whether antral biopsies are enough for confirming Helicobacter pylori eradication with the "new" one week triple therapies with omeprazole...
  82. ncbi Helicobacter pylori and gastroesophageal reflux disease: friends or foes?
    J P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
    Hepatogastroenterology 46:1023-9. 1999
    ..In conclusion, H. pylori and GERD seem to have, in any case, a "friendly" relationship, although it may be transformed into one of "hate" when PPIs enter the scene...
  83. ncbi Re-treatment after Helicobacter pylori eradication failure
    J P Gisbert
    Department of Gastroenterology, Hospital Ramon y Cajal, Universidad de Alcala de Henares, Madrid, Spain
    Eur J Gastroenterol Hepatol 11:1049-54. 1999
    ..Therefore, our aim was to evaluate the appropriate attitude when eradication therapy fails...
  84. ncbi Seven-day 'rescue' therapy after Helicobacter pylori treatment failure: omeprazole, bismuth, tetracycline and metronidazole vs. ranitidine bismuth citrate, tetracycline and metronidazole
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Aliment Pharmacol Ther 13:1311-6. 1999
    ..A 'rescue' therapy with a quadruple combination of O, bismuth (B), tetracycline (T) and metronidazole (M) has been recommended...
  85. ncbi ["Rapid" serology for the diagnosis of Helicobacter pylori infection. Evaluation of its accuracy compared with a gold-standard and its concordance with "classic" serology]
    J P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid
    Gastroenterol Hepatol 23:159-64. 2000
    ....
  86. ncbi Helicobacter pylori eradication: proton pump inhibitor vs. ranitidine bismuth citrate plus two antibiotics for 1 week-a meta-analysis of efficacy
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Aliment Pharmacol Ther 14:1141-50. 2000
    ..To compare the efficacy of proton pump inhibitor vs. ranitidine bismuth citrate (RBC) with two antibiotics for 1 week in Helicobacter pylori eradication...
  87. ncbi 13C-urea breath test for the diagnosis of Helicobacter pylori infection: are basal samples necessary?
    J P Gisbert
    Department of Gastroenterology, Hospital de la Princesa, Universidad Autonoma de Madrid, Spain
    Eur J Gastroenterol Hepatol 12:1201-5. 2000
    ..g. depending on diet). However, the superiority of this strategy has not been sufficiently demonstrated. The elimination of basal samples in the 13C-UBT protocol would have the advantages of higher simplicity and speed...
  88. ncbi Helicobacter pylori infection, gastric metaplasia in the duodenum and the relationship with ulcer recurrence
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Eur J Gastroenterol Hepatol 12:1295-8. 2000
    ..pylori) infection and gastric metaplasia (GM) in the duodenum a large group of patients with duodenal ulcer was evaluated to determine whether these factors are related to the number of ulcer recurrences...
  89. ncbi Proton pump inhibitors versus H2-antagonists: a meta-analysis of their efficacy in treating bleeding peptic ulcer
    J P Gisbert
    Department of Gastroenterology, University Hospital La Princesa, Madrid, Spain
    Aliment Pharmacol Ther 15:917-26. 2001
    ..To evaluate whether proton pump inhibitors are more effective than H2-antagonists (H2-A) for the treatment of bleeding peptic ulcer...
  90. ncbi Are twelve days of omeprazole, amoxicillin and clarithromycin better than six days for treating H. pylori infection in peptic ulcer and in non-ulcer dyspepsia?
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Hepatogastroenterology 48:1383-8. 2001
    ....
  91. ncbi Helicobacter pylori eradication therapy is more effective in peptic ulcer than in non-ulcer dyspepsia
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Eur J Gastroenterol Hepatol 13:1303-7. 2001
    ..To evaluate whether eradication therapy is more effective in peptic ulcer disease (PUD) than in non-ulcer dyspepsia (NUD)...
  92. ncbi Review article: Helicobacter pylori "rescue" regimen when proton pump inhibitor-based triple therapies fail
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Playa de Mojácar 29, Urb Bonanza, 28669 Boadilla del Monte, Madrid, Spain
    Aliment Pharmacol Ther 16:1047-57. 2002
    ..Recently, rifabutin-based rescue therapies have been shown to constitute an encouraging strategy for eradication failures, as they are effective against H. pylori strains resistant to antibiotics...
  93. ncbi Role of partner's infection in reinfection after Helicobacter pylori eradication
    Javier P Gisbert
    Department of Gastroenterology, Hospital de la Princesa, Universidad Autonoma de Madrid, Spain
    Eur J Gastroenterol Hepatol 14:865-71. 2002
    ..To evaluate whether the Helicobacter pylori status of the patient's spouse plays a role in reinfection after eradication success, and to assess the possibility of transmission of H. pylori among partners by using molecular methods...
  94. ncbi [Prevalence of Helicobacter pylori infection in gastroesophageal reflux disease and Barretts esophagus]
    Javier P Gisbert
    Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
    Med Clin (Barc) 119:217-23. 2002
  95. ncbi [Individualized therapy with azathioprine or 6-mercaptopurine by monitoring thiopurine methyl-transferase (TPMT) activity]
    J P Gisbert
    Servicio de Aparato Digestivo Hospital Universitario de La Princesa Madrid Spain
    Rev Clin Esp 202:555-62. 2002
  96. ncbi [Study of the validity of "rapid" serology in diagnosing Helicobacter pylori infection]
    J P Gisbert
    Hospital de la Princesa Madrid España
    Aten Primaria 30:501-6. 2002
    ..To evaluate prospectively the validity of a <<rapid>> serology diagnosis method (using capillary blood) in our ambit, taking for reference a combination of standard diagnostic methods...
  97. ncbi Review article: is there an optimal therapeutic regimen for antimitochondrial antibody-negative primary biliary cirrhosis (autoimmune cholangitis)?
    J P Gisbert
    Servicio de Gastroenterología y Hepatología, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Diego de Leon 62, E 28006 Madrid, Spain
    Aliment Pharmacol Ther 17:17-27. 2003
    ..However, ursodeoxycholic acid may be given when histology reveals bile duct lesions, whereas immunosuppressive therapy should probably be reserved for patients exhibiting interface hepatitis...
  98. ncbi [Comparison between two 13C-urea breath tests for the diagnosis of Helicobacter pylori infection: isotope ratio mass spectrometer versus infrared spectrometer]
    J P Gisbert
    Servicios de Aparato Digestivo Hospital Universitario de la Princesa Madrid Spain
    Gastroenterol Hepatol 26:141-6. 2003
    ..To compare the accuracy of the breath test using the isotope ratio mass spectrometer (IRMS) versus the nondispersive isotope-selective infrared spectrometer (NDIRS) in the diagnosis of Helicobacter pylori infection...
  99. ncbi [Cyclooxygenase-2 and gastroduodenal lesions. Any relationship with Helicobacter pylori ? A systematic review]
    Javier P Gisbert
    Servicio de Aparato Digestivo Hospital Universitario de La Princesa Madrid España
    Med Clin (Barc) 120:550-8. 2003
  100. ncbi [The role of anti-neutrophil cytoplasmic antibodies (ANCA) and anti-Saccharomyces cerevisiae antibodies (ASCA) in inflammatory bowel disease]
    J P Gisbert
    Servicio de Aparato Digestivo Hospital Universitario de La Princesa Madrid Spain
    Gastroenterol Hepatol 26:312-24. 2003
  101. ncbi Validation of the 13c-urea breath test for the initial diagnosis of helicobacter pylori infection and to confirm eradication after treatment
    J P Gisbert
    Servicio de Aparato Digestivo Hospital de la Princesa Madrid Spain
    Rev Esp Enferm Dig 95:121-6, 115-20. 2003
    ..Our objective was to validate the UBT (TAU-KIT) both as an initial diagnostic method for the detection of H. pylori infection and as a method to confirm eradication...