Ramon Estruch

Summary

Country: Spain

Publications

  1. ncbi request reprint Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial
    Ramon Estruch
    Institut d Investigacions Biomèdiques August Pi Sunyer, Municipal Institut for Medical Research, University of Barcelona, and Catalan Institute of Health, Barcelona, Spain
    Ann Intern Med 145:1-11. 2006
  2. doi request reprint Anti-inflammatory effects of the Mediterranean diet: the experience of the PREDIMED study
    Ramon Estruch
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    Proc Nutr Soc 69:333-40. 2010
  3. doi request reprint Effect of a high-fat Mediterranean diet on bodyweight and waist circumference: a prespecified secondary outcomes analysis of the PREDIMED randomised controlled trial
    Ramon Estruch
    Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid, Spain Hospital Clínic, Institut d Investigacions Biomèdiques August Pi Sunyer, University of Barcelona, Barcelona, Spain Electronic address
    Lancet Diabetes Endocrinol 4:666-76. 2016
  4. pmc The immune protective effect of the Mediterranean diet against chronic low-grade inflammatory diseases
    Rosa Casas
    Department of Internal Medicine, Hospital Clinic, Villarroel, 170, 08036 Barcelona, Spain
    Endocr Metab Immune Disord Drug Targets 14:245-54. 2014
  5. pmc Reduced circulating sTWEAK levels are associated with metabolic syndrome in elderly individuals at high cardiovascular risk
    Andrés Díaz-López
    Human Nutrition Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, C Sant Llorenc, 21, Reus, Tarragona 43201, Spain
    Cardiovasc Diabetol 13:51. 2014
  6. pmc Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
    Dolores Corella
    Department of Preventive Medicine and Public Health, School of Medicine, University of Valencia, Valencia, Spain
    Cardiovasc Diabetol 13:5. 2014
  7. pmc Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study
    Marta Guasch-Ferré
    Human Nutrition Unit, University Hospital of Sant Joan de Reus, Faculty of Medicine and Health Sciences, IISPV, Rovira i Virgili University, C Sant Llorenç 21, Reus, 43201, Spain
    BMC Med 12:78. 2014
  8. pmc Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial
    Estefania Toledo
    Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Navarra, Spain
    BMC Med 11:207. 2013
  9. pmc Alcohol intake, wine consumption and the development of depression: the PREDIMED study
    Alfredo Gea
    Department of Preventive Medicine and Public Health, Medical School Clinica Universidad de Navarra, Pamplona, Spain
    BMC Med 11:192. 2013
  10. pmc Blood pressure values and depression in hypertensive individuals at high cardiovascular risk
    Cília Mejía-Lancheros
    Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain
    BMC Cardiovasc Disord 14:109. 2014

Detail Information

Publications109 found, 100 shown here

  1. ncbi request reprint Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial
    Ramon Estruch
    Institut d Investigacions Biomèdiques August Pi Sunyer, Municipal Institut for Medical Research, University of Barcelona, and Catalan Institute of Health, Barcelona, Spain
    Ann Intern Med 145:1-11. 2006
    ..The Mediterranean diet has been shown to have beneficial effects on cardiovascular risk factors...
  2. doi request reprint Anti-inflammatory effects of the Mediterranean diet: the experience of the PREDIMED study
    Ramon Estruch
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    Proc Nutr Soc 69:333-40. 2010
    ..These results support the recommendation of the Med-Diet as a useful tool against CVD...
  3. doi request reprint Effect of a high-fat Mediterranean diet on bodyweight and waist circumference: a prespecified secondary outcomes analysis of the PREDIMED randomised controlled trial
    Ramon Estruch
    Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid, Spain Hospital Clínic, Institut d Investigacions Biomèdiques August Pi Sunyer, University of Barcelona, Barcelona, Spain Electronic address
    Lancet Diabetes Endocrinol 4:666-76. 2016
    ..We assessed the long-term effects of ad libitum, high-fat, high-vegetable-fat Mediterranean diets on bodyweight and waist circumference in older people at risk of cardiovascular disease, most of whom were overweight or obese...
  4. pmc The immune protective effect of the Mediterranean diet against chronic low-grade inflammatory diseases
    Rosa Casas
    Department of Internal Medicine, Hospital Clinic, Villarroel, 170, 08036 Barcelona, Spain
    Endocr Metab Immune Disord Drug Targets 14:245-54. 2014
    ....
  5. pmc Reduced circulating sTWEAK levels are associated with metabolic syndrome in elderly individuals at high cardiovascular risk
    Andrés Díaz-López
    Human Nutrition Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, C Sant Llorenc, 21, Reus, Tarragona 43201, Spain
    Cardiovasc Diabetol 13:51. 2014
    ..We investigated the association between sTWEAK levels and metabolic syndrome (MetS) and its components in older subjects at high cardiovascular risk...
  6. pmc Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
    Dolores Corella
    Department of Preventive Medicine and Public Health, School of Medicine, University of Valencia, Valencia, Spain
    Cardiovasc Diabetol 13:5. 2014
    ..Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related to obesity, its association with other cardiovascular risk factors and disease remains uncertain...
  7. pmc Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study
    Marta Guasch-Ferré
    Human Nutrition Unit, University Hospital of Sant Joan de Reus, Faculty of Medicine and Health Sciences, IISPV, Rovira i Virgili University, C Sant Llorenç 21, Reus, 43201, Spain
    BMC Med 12:78. 2014
    ..The aim was to assess the association between total olive oil intake, its varieties (extra virgin and common olive oil) and the risk of cardiovascular disease and mortality in a Mediterranean population at high cardiovascular risk...
  8. pmc Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial
    Estefania Toledo
    Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Navarra, Spain
    BMC Med 11:207. 2013
    ..Hypertension can be prevented by adopting healthy dietary patterns. Our aim was to assess the 4-year effect on blood pressure (BP) control of a randomized feeding trial promoting the traditional Mediterranean dietary pattern...
  9. pmc Alcohol intake, wine consumption and the development of depression: the PREDIMED study
    Alfredo Gea
    Department of Preventive Medicine and Public Health, Medical School Clinica Universidad de Navarra, Pamplona, Spain
    BMC Med 11:192. 2013
    ..Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and incident depression using repeated measurements of alcohol intake...
  10. pmc Blood pressure values and depression in hypertensive individuals at high cardiovascular risk
    Cília Mejía-Lancheros
    Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain
    BMC Cardiovasc Disord 14:109. 2014
    ..This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk...
  11. pmc Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study
    Cília Mejía-Lancheros
    Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autonoma de Barcelona, Bellaterra, Spain
    BMC Cardiovasc Disord 14:135. 2014
    ..The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population...
  12. doi request reprint "Towards an even healthier Mediterranean diet"
    R Estruch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigació, August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain CIBER OBN, Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Government of Spain, Santiago de Compostela, Spain Electronic address
    Nutr Metab Cardiovasc Dis 23:1163-6. 2013
    ....
  13. pmc Association between dietary phylloquinone intake and peripheral metabolic risk markers related to insulin resistance and diabetes in elderly subjects at high cardiovascular risk
    Martí Juanola-Falgarona
    Universitat Rovira i Virgili, C Sant Llorenç 21, Reus, Spain
    Cardiovasc Diabetol 12:7. 2013
    ..The purpose of the study was to assess the associations between dietary intake of vitamin K and peripheral adipokines and other metabolic risk markers related to insulin resistance and type 2 diabetes mellitus...
  14. pmc Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low
    Carolina Ortega-Azorín
    Department of Preventive Medicine and Public Health, School of Medicine, University of Valencia, Valencia, Spain
    Cardiovasc Diabetol 11:137. 2012
    ..However gene-diet interactions with dietary patterns have not been investigated. Our main aim was to analyze whether these associations are modulated by the level of adherence to the Mediterranean Diet (MedDiet)...
  15. pmc Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial
    Marta Guasch-Ferré
    Human Nutrition Unit, Hospital Universitari de Sant Joan de Reus, Faculty of Medicine and Health Sciences, IISPV Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain
    BMC Med 11:164. 2013
    ..To examine the association between frequency of nut consumption and mortality in individuals at high cardiovascular risk from Spain, a Mediterranean country with a relatively high average nut intake per person...
  16. doi request reprint Primary prevention of cardiovascular disease with a Mediterranean diet
    Ramon Estruch
    Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
    N Engl J Med 368:1279-90. 2013
    ..We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events...
  17. doi request reprint Effects of dietary fibre intake on risk factors for cardiovascular disease in subjects at high risk
    R Estruch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain
    J Epidemiol Community Health 63:582-8. 2009
    ..Thus, the effects of changes in dietary fibre intake on cardiovascular risk factors were assessed over 3 months in free-living high-risk subjects...
  18. doi request reprint Moderate consumption of red wine, but not gin, decreases erythrocyte superoxide dismutase activity: a randomised cross-over trial
    R Estruch
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Nutr Metab Cardiovasc Dis 21:46-53. 2011
    ....
  19. pmc Tomato Sauce Enriched with Olive Oil Exerts Greater Effects on Cardiovascular Disease Risk Factors than Raw Tomato and Tomato Sauce: A Randomized Trial
    Palmira Valderas-Martinez
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, Medicine School, University of Barcelona, Barcelona 08036, Spain
    Nutrients 8:170. 2016
    ..We concluded that tomato intake has beneficial effects on cardiovascular risk factors, especially cooked and enriched with oil. ..
  20. doi request reprint Effects of red wine polyphenols and alcohol on glucose metabolism and the lipid profile: a randomized clinical trial
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Clin Nutr 32:200-6. 2013
    ..The aim of the present study was to compare the effects of moderate consumption of red wine, dealcoholized red wine, and gin on glucose metabolism and the lipid profile...
  21. pmc Dietary α-Linolenic Acid, Marine ω-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvención con DIeta MEDiterránea (PREDIMED) Study
    Aleix Sala-Vila
    CIBER Fisiopatologia de la Obesidad y Nutricion CIBEROBN, Instituto de Salud Carlos III ISCIII, Madrid, Spain A S V Lipid Clinic, Department of Endocrinology and Nutrition, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain A S V, M S M, E R
    J Am Heart Assoc 5:. 2016
    ..7% of total energy) at baseline was related to all-cause and cardiovascular disease mortality. We also examined the effect of meeting the society's recommendation for long-chain n-3 polyunsaturated fatty acids (≥500 mg/day)...
  22. doi request reprint Inhibition of circulating immune cell activation: a molecular antiinflammatory effect of the Mediterranean diet
    Mari Pau Mena
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Instituto de Salud Carlos III, Spain
    Am J Clin Nutr 89:248-56. 2009
    ..Adherence to the Mediterranean diet (Med-Diet) is associated with a reduced risk of cardiovascular disease (CVD). However, the molecular mechanisms involved are not fully understood...
  23. ncbi request reprint Down-regulation of adhesion molecules and other inflammatory biomarkers after moderate wine consumption in healthy women: a randomized trial
    Emilio Sacanella
    Department of Internal Medicine, Hospital Clinic, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Am J Clin Nutr 86:1463-9. 2007
    ..The mechanism for this beneficial effect might be reduced inflammatory responses, as suggested by prospective studies and small clinical trials in men. No studies have evaluated the antiinflammatory effects of wine in women...
  24. doi request reprint High urinary levels of resveratrol metabolites are associated with a reduction in the prevalence of cardiovascular risk factors in high-risk patients
    Raul Zamora-Ros
    Nutrition and Food Science Department, XaRTA INSA, Pharmacy School, University of Barcelona, Spain
    Pharmacol Res 65:615-20. 2012
    ....
  25. doi request reprint Effect of cocoa powder on the modulation of inflammatory biomarkers in patients at high risk of cardiovascular disease
    Maria Monagas
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Am J Clin Nutr 90:1144-50. 2009
    ..Because atherosclerosis is considered a low-grade inflammatory disease, some feeding trials have analyzed the effects of cocoa (an important source of flavonoids) on inflammatory biomarkers, but the results have been controversial...
  26. ncbi request reprint Myocardial antioxidant status in chronic alcoholism
    Francesc Fatjó
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Alcohol Clin Exp Res 29:864-70. 2005
    ..The pathogenesis is multifactorial, with the antioxidant imbalance of cardiac muscle being a potential factor. The current study evaluates myocardial antioxidant status in ethanol consumers and its relation to cardiac damage...
  27. doi request reprint Hypertensive status and lipoprotein oxidation in an elderly population at high cardiovascular risk
    Monica Guxens
    Cardiovascular Risk and Nutrition Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Am J Hypertens 22:68-73. 2009
    ..Our aim was to assess the relationship between the degree of in vivo low-density lipoprotein (oxLDL) oxidation and the hypertensive status in a elderly population at high cardiovascular risk...
  28. ncbi request reprint Decreased tumor necrosis factor-induced adhesion of human monocytes to endothelial cells after moderate alcohol consumption
    Eva Badia
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Spain
    Am J Clin Nutr 80:225-30. 2004
    ..Moderate alcohol consumption protects against ischemic heart disease, possibly through an antiinflammatory effect. However, little is known about the mechanisms by which alcohol may interfere in the development of atherosclerosis...
  29. doi request reprint The Mediterranean diet pattern and its main components are associated with lower plasma concentrations of tumor necrosis factor receptor 60 in patients at high risk for cardiovascular disease
    Mireia Urpi-Sarda
    Department of Internal Medicine, University of Barcelona, Barcelona, Spain
    J Nutr 142:1019-25. 2012
    ..01). This study suggests that a MD reduces TNFR concentrations in patients at high cardiovascular risk...
  30. pmc Effects of Polyphenol, Measured by a Biomarker of Total Polyphenols in Urine, on Cardiovascular Risk Factors After a Long-Term Follow-Up in the PREDIMED Study
    Xiaohui Guo
    Departament of Nutrition and Food Science, XaRTA, INSA, School of Pharmacy, University of Barcelona, Barcelona, Spain
    Oxid Med Cell Longev 2016:2572606. 2016
    ..164; P = 0.036), and diastolic blood pressure (β = -1.316; P = 0.013). Our results suggest that the consumption of more polyphenols, measured as TPE in urine, could exert a protective effect against some cardiovascular risk factors. ..
  31. ncbi request reprint Diagnostic performance of urinary resveratrol metabolites as a biomarker of moderate wine consumption
    Raul Zamora-Ros
    Nutrition and Food Science Department CeRTA, Pharmacy School, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Clin Chem 52:1373-80. 2006
    ..We evaluated resveratrol metabolites, potential biomarkers of wine consumption, in humans after moderate consumption of sparkling, white, or red wines...
  32. doi request reprint Alcohol consumption is associated with high concentrations of urinary hydroxytyrosol
    Helmut Schroder
    CIBER Fisiopatología Obesidad y Nutrición and Biochemistry and Molecular Biology, Instituto de Salud Carlos III, Santiago de Compostela, Spain
    Am J Clin Nutr 90:1329-35. 2009
    ..We hypothesized that the alcohol present in wine could promote endogenous hydroxytyrosol generation...
  33. doi request reprint Virgin olive oil and nuts as key foods of the Mediterranean diet effects on inflammatory biomakers related to atherosclerosis
    Mireia Urpi-Sarda
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, University of Barcelona, C Villarroel, 170, 08036 Barcelona, Spain
    Pharmacol Res 65:577-83. 2012
    ..02). In conclusion, Med-Diet exerts an anti-inflammatory effect on cardiovascular system since it down-regulates cellular and circulating inflammatory biomarkers related to atherogenesis in subjects at high cardiovascular risk...
  34. ncbi request reprint Dealcoholized red wine decreases systolic and diastolic blood pressure and increases plasma nitric oxide: short communication
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Circ Res 111:1065-8. 2012
    ..Experimental studies have shown a potential blood pressure (BP) lowering effect of red wine polyphenols, whereas the effects of ethanol and polyphenols on BP in humans are not yet clear...
  35. doi request reprint Urinary isoxanthohumol is a specific and accurate biomarker of beer consumption
    Paola Quifer-Rada
    Department of Nutrition and Food Science XARTA INSA, School of Pharmacy, University of Barcelona, Barcelona, Spain
    J Nutr 144:484-8. 2014
    ..IX in urine samples was found to be a specific and accurate biomarker of beer consumption and may be a powerful tool in epidemiologic studies...
  36. doi request reprint Mediterranean diet supplemented with nuts reduces waist circumference and shifts lipoprotein subfractions to a less atherogenic pattern in subjects at high cardiovascular risk
    Nágila R T Damasceno
    Lipid Clinic, Endocrinology and Nutrition Service, Biomedical Research Institute August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil
    Atherosclerosis 230:347-53. 2013
    ..We investigated changes in adiposity and lipoprotein subfractions after consumption of the PREDIMED diets...
  37. doi request reprint Effects of wine, alcohol and polyphenols on cardiovascular disease risk factors: evidences from human studies
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, 08036 Barcelona, Spain
    Alcohol Alcohol 48:270-7. 2013
    ..The aim of this review was to focus on the knowledge of the cardiovascular benefits of moderate alcohol consumption, as well as to analyze the effects of the different types of alcoholic beverages...
  38. ncbi request reprint Evidence of apoptosis in chronic alcoholic skeletal myopathy
    Joaquim Fernández-Solà
    Department of Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Hum Pathol 34:1247-52. 2003
    ..However, the specific pathogenic mechanism of apoptosis in chronic skeletal myopathy in alcoholics remains to be elucidated...
  39. ncbi request reprint Inflammatory markers of atherosclerosis are decreased after moderate consumption of cava (sparkling wine) in men with low cardiovascular risk
    Mónica Vázquez-Agell
    Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona 08036, Spain
    J Nutr 137:2279-84. 2007
    ..05). In conclusion, both cava and gin showed antiinflammatory properties; however, cava had a greater protective effect, probably due its polyphenol content...
  40. doi request reprint Resveratrol metabolites in urine as a biomarker of wine intake in free-living subjects: The PREDIMED Study
    Raul Zamora-Ros
    Nutrition and Food Science Department XaRTA, INSA, Pharmacy School, University of Barcelona, 08028 Barcelona, Spain
    Free Radic Biol Med 46:1562-6. 2009
    ..This biomarker would provide an additional tool for investigating more precisely the relationship between wine consumption and health benefits...
  41. doi request reprint The effects of milk as a food matrix for polyphenols on the excretion profile of cocoa (-)-epicatechin metabolites in healthy human subjects
    Elena Roura
    Department of Nutrition and Food Science CeRTA, University of Barcelona, Av Joan XXIII s n, Barcelona 08028, Spain
    Br J Nutr 100:846-51. 2008
    ..Thus, more studies are needed to evaluate the effect of these different metabolite profiles on the body...
  42. doi request reprint The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled, trial
    Maria Teresa Mitjavila
    Department of Physiology, INSA, University of Barcelona, Spain
    Clin Nutr 32:172-8. 2013
    ..However, the effect of the MedDiet on biomarkers for oxidative damage has not been assessed in MetS individuals. We have investigated the effect of the MedDiet on systemic oxidative biomarkers in MetS individuals...
  43. doi request reprint Targeted metabolic profiling of phenolics in urine and plasma after regular consumption of cocoa by liquid chromatography-tandem mass spectrometry
    Mireia Urpi-Sarda
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, 08028 Barcelona, Spain
    J Chromatogr A 1216:7258-67. 2009
    ..The results found herein indicate that 5-(3',4'-dihydroxyphenyl)-gamma-valerolactone and hydroxyphenylacetic acids could be good biomarkers of the regular consumption of cocoa and therefore, of flavanol-rich foods...
  44. doi request reprint Cardioprotective effects of cocoa: clinical evidence from randomized clinical intervention trials in humans
    Sara Arranz
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Mol Nutr Food Res 57:936-47. 2013
    ..However, larger randomized trials are required to definitively establish the impact of cocoa and cocoa products consumption on hard cardiovascular outcomes...
  45. doi request reprint Effect of Mediterranean diet on the expression of pro-atherogenic genes in a population at high cardiovascular risk
    Vicenta Llorente-Cortes
    Cardiovascular Research Center, CSIC ICCC, Hospital Sant Pau, Barcelona, Spain
    Atherosclerosis 208:442-50. 2010
    ..Dietary intervention can thus actively modulate the expression of pro-atherothrombotic genes even in a high-risk population...
  46. pmc A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects: the PREDIMED trial
    Miguel Angel Martinez-Gonzalez
    Prevención con Dieta Mediterránea Network RD 06 0045, Instituto de Salud Carlos III, Spanish Government, Madrid, Spain
    PLoS ONE 7:e43134. 2012
    ..We examined these associations using a 14-item tool of adherence to the Mediterranean diet as exposure and body mass index, waist circumference and waist-to-height ratio (WHtR) as outcomes...
  47. pmc Wine, beer, alcohol and polyphenols on cardiovascular disease and cancer
    Sara Arranz
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, 08036, Spain
    Nutrients 4:759-81. 2012
    ..This review summarizes the main protective effects on the cardiovascular system and cancer resulting from moderate wine and beer intake due mainly to their common components, alcohol and polyphenols...
  48. doi request reprint (1)H-NMR-based metabolomic analysis of the effect of moderate wine consumption on subjects with cardiovascular risk factors
    Rosa Vázquez-Fresno
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, Barcelona, Spain
    Electrophoresis 33:2345-54. 2012
    ..The results show the capacity of this approach to obtain a comprehensive metabolome picture including food metabolome and endogenous biomarkers of moderate wine intake...
  49. doi request reprint Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk
    Cinta Valls-Pedret
    Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    J Alzheimers Dis 29:773-82. 2012
    ..The results reinforce the notion that Mediterranean diet components might counteract age-related cognitive decline...
  50. pmc Mediterranean dietary pattern and depression: the PREDIMED randomized trial
    Almudena Sanchez-Villegas
    Biomedical Research Center Network on Obesity and Nutrition CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
    BMC Med 11:208. 2013
    ..The aim of this study was to compare in a randomized trial the effects of two Mediterranean diets versus a low-fat diet on depression risk after at least 3 years of intervention...
  51. doi request reprint Mediterranean diet reduces 24-hour ambulatory blood pressure, blood glucose, and lipids: one-year randomized, clinical trial
    Mónica Doménech
    From the Lipid Clinic, Endocrinology and Nutrition Service M D, A S V, E R and Hypertension and Vascular Risk Unit, Department of Internal Medicine M D, R E, A C, Institut d Investigacions Biomédiques August Pi Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain Ciber Fisiopatología de la Obesidad y Nutrición CIBERobn, Instituto de Salud Carlos III ISCIII, Madrid, Spain M D, P R, J L, F J G d l C, A S V, R d l T, D C, J S S, V R G, R M L R, E T, R E, E R Department of Family Medicine, Primary Care Division of Seville, San Pablo Health Center, Seville, Spain P R, J L, F J G d l C Cardiovascular and Nutrition Research Group, Institut de Recerca Hospital del Mar, Barcelona
    Hypertension 64:69-76. 2014
    ..3, -13.6, and -4.4 mg/dL (P=0.043), respectively. In high-risk individuals, most with treated hypertension, MedDiets supplemented with extravirgin olive oil or nuts reduced 24-hour ambulatory BP, total cholesterol, and fasting glucose...
  52. ncbi request reprint The effect of polyphenol consumption on blood pressure
    Alexander Medina-Remón
    Nutrition and Food Science Department, XaRTA, INSA Pharmacy School, University of Barcelona, Spain
    Mini Rev Med Chem 13:1137-49. 2013
    ....
  53. doi request reprint Microbial metabolomic fingerprinting in urine after regular dealcoholized red wine consumption in humans
    María Boto-Ordóñez
    Biomarkers and Nutritional and Food Metabolomics Research Group, Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, Avenida Joan XXIII s n, 08028 Barcelona, Spain
    J Agric Food Chem 61:9166-75. 2013
    ..These findings provide the most complete metabolic fingerprinting after wine consumption, amplifying the spectrum of microbial derived metabolites and their potential bioactivity related with health benefits. ..
  54. doi request reprint Changes in ultrasound-assessed carotid intima-media thickness and plaque with a Mediterranean diet: a substudy of the PREDIMED trial
    Aleix Sala-Vila
    From the Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain A S V, E R Ciber Fisiopatología de la Obesidad y Nutrición CIBERobn, Instituto de Salud Carlos III ISCIII, Madrid, Spain A S V, E S R M, I N, R d l T, D C, V R G, M C L S, X P, J R, M Á M G, R E, E R Department of Internal Medicine, IDIBAPS, Hospital Clinic, Barcelona, Spain E S R M, R E Diagnostic Imaging Centre, IDIBAPS, Hospital Clinic, Barcelona, Spain R G, I N Human Pharmacology and Clinical Neurosciences Research Group, Institut de Investigacions Mèdiques Hospital del Mar, Barcelona, Spain R d l T Department of Preventive Medicine, University of Valencia, Valencia, Spain D C Instituto de la Grasa
    Arterioscler Thromb Vasc Biol 34:439-45. 2014
    ..We assessed the effect of both supplemented MedDiets on internal carotid intima-media thickness (ICA-IMT) and plaque height, the ultrasound features that best predict future cardiovascular events, in subjects at high cardiovascular risk...
  55. ncbi request reprint Different effects of red wine and gin consumption on inflammatory biomarkers of atherosclerosis: a prospective randomized crossover trial. Effects of wine on inflammatory markers
    Ramon Estruch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Atherosclerosis 175:117-23. 2004
    ..We embarked on a randomized, crossover, single-blinded trial to evaluate the effects of wine and gin on inflammatory biomarkers of atherosclerosis...
  56. doi request reprint Gut and microbial resveratrol metabolite profiling after moderate long-term consumption of red wine versus dealcoholized red wine in humans by an optimized ultra-high-pressure liquid chromatography tandem mass spectrometry method
    Maria Rotchés-Ribalta
    Nutrition and Food Science Department, XaRTA INSA, Pharmacy Faculty, University of Barcelona, Av Joan XXIII, S N, 08028 Barcelona, Spain
    J Chromatogr A 1265:105-13. 2012
    ..In this sense, having a more precise concentration value of all the resveratrol metabolites in target tissues would finally lead to a better interpretation of the obtained results...
  57. doi request reprint Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis: a randomized clinical trial
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, Barcelona, Spain
    Am J Clin Nutr 95:326-34. 2012
    ..Few clinical studies have focused on the alcohol-independent cardiovascular effects of the phenolic compounds of red wine (RW)...
  58. doi request reprint Evaluation of myocyte proliferation in alcoholic cardiomyopathy: telomerase enzyme activity (TERT) compared with Ki-67 expression
    Meritxell Lluis
    Alcohol Research Unit, Department of Internal Medicine, Institut d Investigació August Pi i Sunyer, Hospital Clinic, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Alcohol Alcohol 46:534-41. 2011
    ..We evaluated myocyte proliferation response in the heart of chronic alcoholic donors with telomerase activity (telomerase reverse transcriptase (TERT)) compared with Ki-67 nuclear expression...
  59. doi request reprint Determination of resveratrol and piceid in beer matrices by solid-phase extraction and liquid chromatography-tandem mass spectrometry
    Gemma Chiva-Blanch
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, Av Joan XXIII s n, 08028 Barcelona, Spain
    J Chromatogr A 1218:698-705. 2011
    ..Overall, beer is one of the products with the lowest levels of total resveratrol (μg/L), and despite its high consumption it should not be considered as a representative source of resveratrol...
  60. ncbi request reprint Intake of Total Polyphenols and Some Classes of Polyphenols Is Inversely Associated with Diabetes in Elderly People at High Cardiovascular Disease Risk
    Anna Tresserra-Rimbau
    Nutrition and Food Science Department, XaRTA Reference Network in Food Technology, INSA Nutrition and Food Safety Research Institute, Pharmacy School, and CIBEROBN Fisiopatología de la Obesidad y Nutrición Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition, Instituto de Salud Carlos III Carlos III Health Institute, Madrid, Spain
    J Nutr . 2016
    ..Higher consumption of some polyphenols has been associated with a reduced risk of diabetes. However, no studies have evaluated the relation between all polyphenol subclasses and the incidence of diabetes...
  61. doi request reprint Long-Term Immunomodulatory Effects of a Mediterranean Diet in Adults at High Risk of Cardiovascular Disease in the PREvención con DIeta MEDiterránea (PREDIMED) Randomized Controlled Trial
    Rosa Casas
    Department of Internal Medicine, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Barcelona, Spain CIBEROBN Fisiopatología de la Obesidad y Nutrición Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition, Instituto de Salud Carlos III Carlos III Health Institute, Madrid, Spain
    J Nutr 146:1684-93. 2016
    ..The Mediterranean diet (MedDiet) has demonstrated short-term anti-inflammatory effects, but little is known about its long-term immunomodulatory properties...
  62. doi request reprint Long-chain n-3 PUFA supplied by the usual diet decrease plasma stearoyl-CoA desaturase index in non-hypertriglyceridemic older adults at high vascular risk
    Ana M Pérez-Heras
    Lipid Clinic, Endocrinology and Nutrition Service, Biomedical Research Institute August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain Ciber Fisiopatología de la Obesidad y Nutrición CIBERobn, Instituto de Salud Carlos III ISCIII, Madrid, Spain
    Clin Nutr . 2016
    ..The effect of long-chain n-3 PUFA (LCn-3PUFA) supplied by the regular diet, in the absence of fatty fish or fish oil supplementation, remains to be explored...
  63. pmc The effects of the mediterranean diet on biomarkers of vascular wall inflammation and plaque vulnerability in subjects with high risk for cardiovascular disease. A randomized trial
    Rosa Casas
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain CIBER 06 03 Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid, Spain
    PLoS ONE 9:e100084. 2014
    ..Adherence to the Mediterranean diet (MD) is associated with reduced morbidity and mortality due to cardiovascular disease. However, how the MD exerts its effects is not fully known...
  64. doi request reprint Light gazpachos contain higher phytochemical levels than conventional gazpachos
    Anna Vallverdú-Queralt
    Nutrition and Food Science Department, University of Barcelona, Barcelona, Spain
    Food Sci Technol Int 19:377-85. 2013
    ..Higher consumption levels of phenolic compounds, which are greater in light products, along with caloric restriction and physical activity may be helpful in preventing obesity. ..
  65. ncbi request reprint Milk does not affect the bioavailability of cocoa powder flavonoid in healthy human
    Elena Roura
    Department of Nutrition and Food Science CeRTA, University of Barcelona, Barcelona, Spain
    Ann Nutr Metab 51:493-8. 2007
    ..The food matrix is one the factors than can affect their bioavailability, but previous studies have concluded rather contradictory results about the effect of milk on the bioavailability of polyphenols...
  66. doi request reprint Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells
    Maria Monagas
    Department of Internal Medicine, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, Hospital Clinic, Universitat de Barcelona, 08036 Barcelona, Spain
    Br J Nutr 102:201-6. 2009
    ....
  67. doi request reprint Serum sterol responses to increasing plant sterol intake from natural foods in the Mediterranean diet
    Veronica Escurriol
    Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomèdiques Ausgust Pi Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Eur J Nutr 48:373-82. 2009
    ..Phytosterols in natural foods are thought to inhibit cholesterol absorption. The Mediterranean diet is rich in phytosterol-containing plant foods...
  68. ncbi request reprint Effect of a traditional Mediterranean diet on lipoprotein oxidation: a randomized controlled trial
    Montserrat Fito
    Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, IMIM Hospital del Mar, Barcelona, Spain
    Arch Intern Med 167:1195-203. 2007
    ..Despite the richness in antioxidants of the Mediterranean diet, to our knowledge, no randomized controlled trials have assessed its effect on in vivo lipoprotein oxidation...
  69. doi request reprint Replacing red meat and processed red meat for white meat, fish, legumes or eggs is associated with lower risk of incidence of metabolic syndrome
    Nerea Becerra-Tomás
    Human Nutrition Unit, Faculty of Medicine and Health Sciences, Biochemistry and Biotechnology Department, Universitat Rovira i Virgili, and Hospital Universitari de Sant Joan de Reus, IISPV, Reus, Spain Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición CIBERobn, Instituto de Salud Carlos III ISCIII, Madrid, Spain
    Clin Nutr 35:1442-1449. 2016
    ..We investigated associations between total consumption of meat and its subtypes and incident MetS and estimated the effect of substituting RM or PRM for alternative protein-rich foods...
  70. pmc Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions
    Marta Guasch-Ferré
    Departments of Nutrition and Human Nutrition Department, Pere Virgili Research Institute, University Hospital of Sant Joan de Reus, Rovira i Virgili University, Reus, Spain The Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition, Health Institute Carlos III, Madrid, Spain
    Am J Clin Nutr 103:1408-16. 2016
    ..However, to our knowledge, this association has not been evaluated in the context of primary cardiovascular prevention...
  71. pmc Polyphenol intake from a Mediterranean diet decreases inflammatory biomarkers related to atherosclerosis: a substudy of the PREDIMED trial
    Alexander Medina-Remón
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Br J Clin Pharmacol 83:114-128. 2017
    ..In addition, high polyphenol intake improves cardiovascular risk factors- mainly BP and the lipid profile...
  72. doi request reprint Consumption of Yogurt, Low-Fat Milk, and Other Low-Fat Dairy Products Is Associated with Lower Risk of Metabolic Syndrome Incidence in an Elderly Mediterranean Population
    Nancy Babio
    Human Nutrition Unit, Faculty of Medicine and Health Sciences, Biochemistry and Biotechnology Department, Rovira i Virgili University, and Saint Joan de Reus University Hospital, Pere Virgili Health Research Institute, Reus, Spain Center of Biomedical Research in Physiopathology of Obesity and Nutrition CIBEROBN and Prevention with Mediterranean Diet Research Network PREDIMED, Instituto de Salud Carlos III, Madrid, Spain
    J Nutr 145:2308-16. 2015
    ..The association between consumption of dairy products and the risk of developing metabolic syndrome (MetS) is unclear...
  73. doi request reprint Mediterranean Diet, Retinopathy, Nephropathy, and Microvascular Diabetes Complications: A Post Hoc Analysis of a Randomized Trial
    Andrés Díaz-López
    Human Nutrition Unit, Biochemistry and Biotechnology Department, Faculty of Medicine and Health Sciences, Institut d Investigació Sanitària Pere Virgili IISPV, Rovira i Virgili University, Reus, Spain Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
    Diabetes Care 38:2134-41. 2015
    ..We hypothesized that a nutritional intervention based on the Mediterranean diet (MedDiet) would have greater protective effect on diabetic retinopathy and nephropathy than a low-fat control diet...
  74. doi request reprint Dietary fat intake and risk of cardiovascular disease and all-cause mortality in a population at high risk of cardiovascular disease
    Marta Guasch-Ferré
    Human Nutrition Unit, University Hospital of Sant Joan de Reus, Department of Biochemistry and Biotechnology, Faculty of Medicine and Health Sciences, IISPV, Rovira i Virgili University, Reus, Spain Centro de Investigación Biomédica en Red de fisiopatología de la obesidad y nutrición CIBERobn, Institute of Health Carlos III, Madrid, Spain
    Am J Clin Nutr 102:1563-73. 2015
    ..Dietary fat quality and fat replacement are more important for cardiovascular disease (CVD) prevention than is total dietary fat intake...
  75. doi request reprint Moderate red wine consumption is associated with a lower prevalence of the metabolic syndrome in the PREDIMED population
    Anna Tresserra-Rimbau
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy School, University of Barcelona, Barcelona, Spain
    Br J Nutr 113:S121-30. 2015
    ..In conclusion, moderate RW consumption is associated with a lower prevalence of the MetS in an elderly Mediterranean population at a high cardiovascular risk...
  76. doi request reprint A provegetarian food pattern and reduction in total mortality in the Prevención con Dieta Mediterránea (PREDIMED) study
    Miguel A Martinez-Gonzalez
    From the Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain MAM G and AS T the CIBER Fisiopatologia de la Obesidad y Nutricion DC, JS S, ER, MF, RML R, HS, Jl, and RE, CIBER Epidemiologia y Salud Pública HS, and the PREDIMED Network, Instituto de Salud Carlos III RE, JS S, FA, EG G, VR G, RML R, LS M, XP, and MÁM G, Spain the Department of Internal Medicine RE and the Lipid Clinic, Department of Endocrinology and Nutrition ER, Institut d Investigacions Biomèdiques August Pi Sunyer, Hospital Clinic de Barcelona, University of Barcelona, Barcelona, Spain the Human Nutrition Department, Institut d Investigacions Sanitàries Pere i Virgili, Universitat Rovira i Virgili, Reus JS S the Cardiovascular and Nutrition Research Group, Institut de Recerca Hospital del Mar, Barcelona,
    Am J Clin Nutr 100:320S-8S. 2014
    ..A provegetarian food pattern (FP) emphasizing preference for plant-derived foods might reduce all-cause mortality...
  77. doi request reprint A metabolomics-driven approach to predict cocoa product consumption by designing a multimetabolite biomarker model in free-living subjects from the PREDIMED study
    Mar Garcia-Aloy
    Biomarkers and Nutrimetabolomic Lab, Nutrition and Food Science Department, XaRTA, INSA, Campus Torribera, Pharmacy Faculty, University of Barcelona, Spain Ingenio CONSOLIDER Program, Fun C Food CSD2007 063, Spain
    Mol Nutr Food Res 59:212-20. 2015
    ..The aim of the current study was to apply an untargeted metabolomics strategy to characterize a model of cocoa intake biomarkers in a free-living population...
  78. doi request reprint Metabolomic pattern analysis after mediterranean diet intervention in a nondiabetic population: a 1- and 3-year follow-up in the PREDIMED study
    Rosa Vázquez-Fresno
    Biomarkers and Nutrimetabolomic Lab, Nutrition and Food Science Department, XaRTA, INSA, Campus Torribera, Pharmacy Faculty, University of Barcelona, Barcelona 08028, Spain
    J Proteome Res 14:531-40. 2015
    ....
  79. pmc Obesity indexes and total mortality among elderly subjects at high cardiovascular risk: the PREDIMED study
    Miguel A Martinez-Gonzalez
    Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos II, Madrid, Spain The PREDIMED Prevención con Dieta Mediterránea Network RD 06 0045 Instituto de Salud Carlos III, Madrid, Spain Department of Preventive Medicine and Public Health, University of Navarra Osasunbidea, Servicio Navarro de Salud, Pamplona, Spain
    PLoS ONE 9:e103246. 2014
    ..Studies specifically assessing these indexes in large cohorts are scarce. It would also be interesting to know whether a dietary intervention may counterbalance the adverse effects of adiposity on mortality...
  80. doi request reprint Novel multimetabolite prediction of walnut consumption by a urinary biomarker model in a free-living population: the PREDIMED study
    Mar Garcia-Aloy
    Biomarkers and Nutrimetabolomic Lab, Nutrition and Food Science Department, XaRTA, INSA, Campus Torribera, Pharmacy Faculty, University of Barcelona, Barcelona 08028, Spain
    J Proteome Res 13:3476-83. 2014
    ....
  81. ncbi request reprint Evidence of apoptosis in alcoholic cardiomyopathy
    Joaquim Fernández-Solà
    Department of Internal Medicine, Hospital Clinic, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    Hum Pathol 37:1100-10. 2006
    ..Proapoptotic mechanisms are activated in alcoholic patients without heart damage...
  82. doi request reprint Effect of milk on the urinary excretion of microbial phenolic acids after cocoa powder consumption in humans
    Mireia Urpi-Sarda
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, Barcelona, Spain
    J Agric Food Chem 58:4706-11. 2010
    ..In conclusion, milk partially affects the formation of microbial phenolic acids derived from the colonic degradation of procyanidins and other compounds present in cocoa powder...
  83. doi request reprint Determinants of the omega-3 index in a Mediterranean population at increased risk for CHD
    Aleix Sala-Vila
    Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomèdiques August Pi Sunyer, Unitat de Lípids, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Br J Nutr 106:425-31. 2011
    ..Nevertheless, the high omega-3 index could at least partially explain the paradox of low rates of fatal CHD in Spain despite a high background prevalence of cardiovascular risk factors...
  84. doi request reprint Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets
    Maria Rotchés-Ribalta
    Nutrition and Food Science Department, XaRTA INSA, Pharmacy Faculty, University of Barcelona, Av Joan XXIII, S N, Barcelona, Spain
    Pharmacol Res 66:375-82. 2012
    ..1-3.6-fold higher urinary concentrations of microbial metabolites were observed after GE intervention at 12-24h urinary fraction. Therefore, supplement intake could be also a way to bring resveratrol benefits to human health...
  85. ncbi request reprint Total polyphenol intake estimated by a modified Folin-Ciocalteu assay of urine
    Elena Roura
    Department of Nutrition, Institut d Investigacio Biomedica August Pi i Sunyer, IDIBAPS, University of Barcelona, Barcelona, Spain
    Clin Chem 52:749-52. 2006
    ..Measurement of polyphenol content excreted in urine as an indicator of polyphenol consumption may offer a routine screening method that could be used for these pathologies...
  86. doi request reprint Rapid Folin-Ciocalteu method using microtiter 96-well plate cartridges for solid phase extraction to assess urinary total phenolic compounds, as a biomarker of total polyphenols intake
    Alexander Medina-Remón
    Nutrition and Food Science Department, XaRTA, INSA Pharmacy School, University of Barcelona, Av Joan XXIII s n, 08028 Barcelona, Spain
    Anal Chim Acta 634:54-60. 2009
    ..The method is fast and simple and it allows analysis of a large number of samples at the same time...
  87. pmc Polyphenol intake and mortality risk: a re-analysis of the PREDIMED trial
    Anna Tresserra-Rimbau
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy School, University of Barcelona, Barcelona, Spain
    BMC Med 12:77. 2014
    ..Our aim was to evaluate whether polyphenol intake is associated with all-cause mortality in subjects at high cardiovascular risk...
  88. doi request reprint Influence of olive oil on carotenoid absorption from tomato juice and effects on postprandial lipemia
    Sara Arranz
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Faculty of Medicine, University of Barcelona, Barcelona, Spain CIBER CB06 03 Fisiopatología de la Obesidad y la Nutrición, CIBEROBN, Institute of Health Carlos III, Madrid, Spain
    Food Chem 168:203-10. 2015
    ..LDL cholesterol and total cholesterol decreased significantly 6h after the consumption of TJ with oil, which significantly correlated with an increase of trans-lycopene and 5-cis-lycopene, respectively. ..
  89. doi request reprint Socioeconomic status and health inequalities for cardiovascular prevention among elderly Spaniards
    Cília Mejía-Lancheros
    Departamento de Pediatria, Obstetricia, Ginecología y Medicina Preventiva, Universitat Autonoma de Barcelona, Barcelona, Spain
    Rev Esp Cardiol (Engl Ed) 66:803-11. 2013
    ....
  90. doi request reprint Increased myostatin activity and decreased myocyte proliferation in chronic alcoholic cardiomyopathy
    Joaquim Fernández-Solà
    Alcohol Research Unit, Hospital Clinic, Institut d Investigació August Pi i Sunyer, Department of Medicine, University of Barcelona, Barcelona, Spain
    Alcohol Clin Exp Res 35:1220-9. 2011
    ..Myostatin is upregulated after cardiac damage and by alcohol consumption thereby decreasing myocyte renewal. We assess the potential role of alcohol in inducing myocyte apoptosis as well as in inhibiting myocyte proliferation...
  91. doi request reprint Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk
    Andrés Díaz-López
    Human Nutrition Unit, IISPV, Universitat Rovira i Virgili, Reus, Spain
    Clin Nutr 32:606-12. 2013
    ..The aim was to examine the associations between macronutrient intake and the prevalence of chronic kidney disease (CKD) or microalbuminuria (MiA) in individuals at high cardiovascular risk...
  92. doi request reprint Polyphenols excreted in urine as biomarkers of total polyphenol intake
    Alexander Medina-Remón
    Nutrition and Food Science Department, XaRTA, Instituto de Investigaciónen Nutrición y Seguridad Alimentaria, Pharmacy School, University of Barcelona, Barcelona, Spain
    Bioanalysis 4:2705-13. 2012
    ..A precise estimation of polyphenol consumption requires blood or urine sample biomarkers, although their association is usually highly complex...
  93. ncbi request reprint Effects of alcohol withdrawal on 24 hour ambulatory blood pressure among alcohol-dependent patients
    Ramon Estruch
    Alcohol Unit, Department of Internal Medicine, Hospital Clinic, University of Barcelona, Institut de Investigacions Biomediques August Pi i Sunyer, Spain
    Alcohol Clin Exp Res 27:2002-8. 2003
    ..We embarked on a study to determine whether different subgroups of alcohol-dependent patients may be identified in relation to the effect of alcohol on BP...
  94. doi request reprint The non-alcoholic fraction of beer increases stromal cell derived factor 1 and the number of circulating endothelial progenitor cells in high cardiovascular risk subjects: a randomized clinical trial
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain CIBER CB06 03 Fisiopatología de la Obesidad y la Nutrición, CIBERobn and RETIC RD06 0045, Spain
    Atherosclerosis 233:518-24. 2014
    ..Nevertheless, no study has been carried out on the effects of moderate beer consumption on the number of circulating EPC in high cardiovascular risk patients...
  95. pmc Effects of 1-year intervention with a Mediterranean diet on plasma fatty acid composition and metabolic syndrome in a population at high cardiovascular risk
    Jordi Mayneris-Perxachs
    Department of Nutrition and Food Science XARTA INSA, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
    PLoS ONE 9:e85202. 2014
    ..The aim of the present study was to analyze the influence of a Mediterranean dietary pattern, as assessed by the biomarkers of food supplied, on the plasma fatty acid composition and its relation with MetS after 1 year of intervention...
  96. ncbi request reprint Up-regulation of myocardial L-type Ca2+ channel in chronic alcoholic subjects without cardiomyopathy
    Francesc Fatjó
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Alcohol Clin Exp Res 31:1099-105. 2007
    ..This study was designed to evaluate the density and function of myocardial L-type Ca(2+) channel receptors in organ donors with chronic alcoholism and controls...
  97. ncbi request reprint Human urine: epicatechin metabolites and antioxidant activity after cocoa beverage intake
    Elena Roura
    Department of Nutrition and Food Science, University of Barcelona, Barcelona, Spain
    Free Radic Res 41:943-9. 2007
    ..Significance of TAC increase was found in urine samples excreted during 0-6 and 6-12 h (66.6 and 72.67%, respectively, with respect to the 0 h)...
  98. doi request reprint Analytical condition setting a crucial step in the quantification of unstable polyphenols in acidic conditions: analyzing prenylflavanoids in biological samples by liquid chromatography-electrospray ionization triple quadruple mass spectrometry
    Paola Quifer-Rada
    Department of Nutrition and Food Science XARTA INSA, School of Pharmacy, University of Barcelona, Barcelona, Spain
    Anal Chem 85:5547-54. 2013
    ..The method was applied to quantify 10 human samples of urine and was able to quantify prenylflavanoids in urine after the consumption of a single dose of beer (330 mL)...
  99. ncbi request reprint Influence of nutritional status on alcoholic myopathy
    José M Nicolás
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Am J Clin Nutr 78:326-33. 2003
    ..Muscle weakness and structural changes in striated skeletal muscle are common in persons with chronic alcoholism...
  100. pmc Cross-sectional assessment of nut consumption and obesity, metabolic syndrome and other cardiometabolic risk factors: the PREDIMED study
    Núria Ibarrola-Jurado
    Human Nutrition Unit, Hospital Universitari de Sant Joan de Reus, Institut d Investigació Sanitària Pere Virgili IISPV, Universitat Rovira i Virgili, Reus, Spain
    PLoS ONE 8:e57367. 2013
    ..Limited data are available on the epidemiological associations between nut intake and cardiometabolic risk factors...
  101. doi request reprint Validation of a new LC-MS/MS method for the detection and quantification of phenolic metabolites from tomato sauce in biological samples
    Miriam Martínez-Huelamo
    Department of Nutrition and Food Science XARTA INSA, School of Pharmacy, University of Barcelona, Barcelona, Spain
    J Agric Food Chem 60:4542-9. 2012
    ..The method allowed detection and quantification limits of 0.5-29 and 2.0-90 ng mL⁻¹ in urine, respectively, and 0.5-30 and 2.0-105 ng mL⁻¹ in plasma, respectively, for the same phenolic compounds...