Miguel A de Pedro

Summary

Country: Spain

Publications

  1. pmc Constitutive septal murein synthesis in Escherichia coli with impaired activity of the morphogenetic proteins RodA and penicillin-binding protein 2
    M A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    J Bacteriol 183:4115-26. 2001
  2. ncbi request reprint Fast lysis of Escherichia coli filament cells requires differentiation of potential division sites
    Miguel Angel de Pedro
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    Microbiology 148:79-86. 2002
  3. pmc Branching of Escherichia coli cells arises from multiple sites of inert peptidoglycan
    Miguel A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    J Bacteriol 185:1147-52. 2003
  4. pmc Restricted Mobility of Cell Surface Proteins in the Polar Regions of Escherichia coli
    Miguel A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    J Bacteriol 186:2594-602. 2004
  5. pmc Emerging knowledge of regulatory roles of D-amino acids in bacteria
    Felipe Cava
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA 02115, USA
    Cell Mol Life Sci 68:817-31. 2011
  6. pmc Resistance of rumen bacteria murein to bovine gastric lysozyme
    Maria G Dominguez-Bello
    Dept Biology, University of Puerto Rico, Rio Piedras Campus, PO Box 23360, San Juan Puerto Rico 00931
    BMC Ecol 4:7. 2004
  7. ncbi request reprint Binding to pyruvylated compounds as an ancestral mechanism to anchor the outer envelope in primitive bacteria
    Felipe Cava
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    Mol Microbiol 52:677-90. 2004
  8. doi request reprint Peptidoglycan plasticity in bacteria: stress-induced peptidoglycan editing by noncanonical D-amino acids
    Pilar Horcajo
    Centro de Biologia Molecular Severo Ochoa, Universidad Autónoma de Madrid Consejo Superior de Investigaciones Científicas, Madrid, Spain
    Microb Drug Resist 18:306-13. 2012
  9. doi request reprint Homogeneous incorporation of secondary cell wall polysaccharides to the cell wall of Thermus thermophilus HB27
    Federico Acosta
    Departamento de Biologia Molecular, Centro de Biologia Molecular Severo Ochoa, Universidad Autónoma de Madrid Consejo Superior de Investigaciones Científicas, Campus de la UAM, 28049, Madrid, Spain
    Extremophiles 16:485-95. 2012
  10. ncbi request reprint Patchiness of murein insertion into the sidewall of Escherichia coli
    Miguel A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Facultad de Ciencias, 28049 Madrid, Spain
    Microbiology 149:1753-61. 2003

Collaborators

  • Felipe Cava
  • W D Donachie
  • J V Holtje
  • Federico Acosta
  • Pilar Horcajo
  • Lakshmi Prasad Potluri
  • Silvia M González-Leiza
  • Jose Berenguer
  • Maria G Dominguez-Bello
  • Pablo Castán
  • Kevin D Young
  • Juan A Ayala
  • Matthias Leippe
  • Fabian Michelangeli
  • Marie C Ruiz
  • M Andreina Pacheco
  • Renata Moreno
  • Cristina Vallés
  • Eddy Caro
  • Olga Zafra
  • Heinz Schwarz

Detail Information

Publications13

  1. pmc Constitutive septal murein synthesis in Escherichia coli with impaired activity of the morphogenetic proteins RodA and penicillin-binding protein 2
    M A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    J Bacteriol 183:4115-26. 2001
    ..Furthermore, the segregation results confirm that round cells of rodA mutants do divide in alternate, perpendicular planes as previously proposed (K. J. Begg and W. D. Donachie, J. Bacteriol. 180:2564-2567, 1998)...
  2. ncbi request reprint Fast lysis of Escherichia coli filament cells requires differentiation of potential division sites
    Miguel Angel de Pedro
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    Microbiology 148:79-86. 2002
    ..Our results strongly support that beta-lactam-induced lysis occurs preferentially at division sites because of the activation of zonal murein synthesis at the initiation of septation...
  3. pmc Branching of Escherichia coli cells arises from multiple sites of inert peptidoglycan
    Miguel A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    J Bacteriol 185:1147-52. 2003
    ..These observations suggest that in dacA mutants, branches and other morphological anomalies may arise from split polar caps or by de novo generation of new poles built around inert peptidoglycan patches in the side walls of the cell...
  4. pmc Restricted Mobility of Cell Surface Proteins in the Polar Regions of Escherichia coli
    Miguel A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    J Bacteriol 186:2594-602. 2004
    ..Our results indicate that the mobility of at least some cell envelope proteins is restrained at regions in correspondence with underlying areas of inert murein...
  5. pmc Emerging knowledge of regulatory roles of D-amino acids in bacteria
    Felipe Cava
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA 02115, USA
    Cell Mol Life Sci 68:817-31. 2011
    ....
  6. pmc Resistance of rumen bacteria murein to bovine gastric lysozyme
    Maria G Dominguez-Bello
    Dept Biology, University of Puerto Rico, Rio Piedras Campus, PO Box 23360, San Juan Puerto Rico 00931
    BMC Ecol 4:7. 2004
    ..In this work we characterized the biological activities of bovine gastric secretions against membranes, purified murein and bacteria...
  7. ncbi request reprint Binding to pyruvylated compounds as an ancestral mechanism to anchor the outer envelope in primitive bacteria
    Felipe Cava
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    Mol Microbiol 52:677-90. 2004
    ....
  8. doi request reprint Peptidoglycan plasticity in bacteria: stress-induced peptidoglycan editing by noncanonical D-amino acids
    Pilar Horcajo
    Centro de Biologia Molecular Severo Ochoa, Universidad Autónoma de Madrid Consejo Superior de Investigaciones Científicas, Madrid, Spain
    Microb Drug Resist 18:306-13. 2012
    ..In this article, we provide an overview of the origins of research on the effects of D-amino acids in the biology of bacterial cell walls, including their recent implication as key factors for stress-associated PG remodeling...
  9. doi request reprint Homogeneous incorporation of secondary cell wall polysaccharides to the cell wall of Thermus thermophilus HB27
    Federico Acosta
    Departamento de Biologia Molecular, Centro de Biologia Molecular Severo Ochoa, Universidad Autónoma de Madrid Consejo Superior de Investigaciones Científicas, Campus de la UAM, 28049, Madrid, Spain
    Extremophiles 16:485-95. 2012
    ..These data support that synthesis of SCWP takes place in disperse and homogeneous form all over the cell surface, in contrast to the zonal incorporation at the cell centre recently demonstrated for SlpA...
  10. ncbi request reprint Patchiness of murein insertion into the sidewall of Escherichia coli
    Miguel A de Pedro
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Facultad de Ciencias, 28049 Madrid, Spain
    Microbiology 149:1753-61. 2003
    ....
  11. ncbi request reprint The periplasmic space in Thermus thermophilus: evidence from a regulation-defective S-layer mutant overexpressing an alkaline phosphatase
    Pablo Castán
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain
    Extremophiles 6:225-32. 2002
    ..The potential application of the HB8(Delta)UTR1 mutant for the overexpression of periplasmic thermophilic proteins is discussed...
  12. pmc AmpH, a bifunctional DD-endopeptidase and DD-carboxypeptidase of Escherichia coli
    Silvia M González-Leiza
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, C Nicola s Cabrera 1, Madrid, 28049 Madrid, Spain
    J Bacteriol 193:6887-94. 2011
    ..The wide substrate spectrum of the DD-peptidase activities associated with AmpH supports a role for this protein in PG remodeling or recycling...
  13. pmc Escherichia coli low-molecular-weight penicillin-binding proteins help orient septal FtsZ, and their absence leads to asymmetric cell division and branching
    Lakshmi Prasad Potluri
    Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Mol Microbiol 84:203-24. 2012
    ..Only later, after normal cell wall elongation separates the patches, do branches become visible. Thus, a relationship between the LMW PBPs and cytoplasmic FtsZ ultimately affects cell division and overall shape...