Borja Ibanez

Summary

Affiliation: Centro Nacional de Investigaciones Cardiovasculares
Country: Spain

Publications

  1. doi request reprint Evolving therapies for myocardial ischemia/reperfusion injury
    Borja Ibanez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Hospital Clínico San Carlos, Madrid, Spain Electronic address
    J Am Coll Cardiol 65:1454-71. 2015
  2. pmc Aragon workers' health study--design and cohort description
    Jose A Casasnovas
    Cardiovascular Research Unit, Instituto Aragones de Ciencias de la Salud I CS, Zaragoza, Spain
    BMC Cardiovasc Disord 12:45. 2012
  3. doi request reprint Study design for the "effect of METOprolol in CARDioproteCtioN during an acute myocardial InfarCtion" (METOCARD-CNIC): a randomized, controlled parallel-group, observer-blinded clinical trial of early pre-reperfusion metoprolol administration in ST-segmen
    Borja Ibanez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain
    Am Heart J 164:473-480.e5. 2012
  4. doi request reprint Lethal myocardial reperfusion injury: a necessary evil?
    Borja Ibanez
    Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III C N I C, Madrid, Spain
    Int J Cardiol 151:3-11. 2011
  5. doi request reprint [Modulation of the beta-adrenergic system during acute myocardial infarction: rationale for a new clinical trial]
    Borja Ibanez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Espana
    Rev Esp Cardiol 64:28-33. 2011
  6. doi request reprint Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Borja Ibanez
    From Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain B I, G P, L F F, A M, A F O, J M G R, A G A, J J B, P L R, R F J, M D R, N E, J G P, D S R, S P, G S, V F Hospital Clínico San Carlos IdISSC, Madrid, Spain B I, C M, A F O, R F J, B R M, C A, J C G R, R H A Servicio de Urgencia Médica de Madrid SUMMA 112, Madrid, Spain V S B, A M, J V, M J F C Hospital Universitario Quirón, Madrid
    Circulation 128:1495-503. 2013
  7. doi request reprint Safety and efficacy of intense antithrombotic treatment and percutaneous coronary intervention deferral in patients with large intracoronary thrombus
    Mauro Echavarría-Pinto
    Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain
    Am J Cardiol 111:1745-50. 2013
  8. doi request reprint Fractional flow reserve and minimum Pd/Pa ratio during intravenous adenosine infusion: very similar but not always the same
    Mauro Echavarría-Pinto
    Hospital Clinico San Carlos and Centro Nacional de Investigaciónes Cardiovasculares Carlos III CNIC, Madrid, Spain
    EuroIntervention 11:1013-9. 2016
  9. doi request reprint Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction)
    Gonzalo Pizarro
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Hospital Universitario Quirón Universidad Europea de Madrid, Madrid, Spain
    J Am Coll Cardiol 63:2356-62. 2014
  10. doi request reprint Pathophysiology Underlying the Bimodal Edema Phenomenon After Myocardial Ischemia/Reperfusion
    Rodrigo Fernández-Jiménez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Hospital Universitario Clínico San Carlos, Madrid, Spain
    J Am Coll Cardiol 66:816-28. 2015

Collaborators

Detail Information

Publications42

  1. doi request reprint Evolving therapies for myocardial ischemia/reperfusion injury
    Borja Ibanez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Hospital Clínico San Carlos, Madrid, Spain Electronic address
    J Am Coll Cardiol 65:1454-71. 2015
    ..In this review, we examine the past, present, and future therapies to reduce ischemia/reperfusion injury...
  2. pmc Aragon workers' health study--design and cohort description
    Jose A Casasnovas
    Cardiovascular Research Unit, Instituto Aragones de Ciencias de la Salud I CS, Zaragoza, Spain
    BMC Cardiovasc Disord 12:45. 2012
    ..The objective of this paper is to describe the study design, aims and baseline characteristics of participants in the AWHS...
  3. doi request reprint Study design for the "effect of METOprolol in CARDioproteCtioN during an acute myocardial InfarCtion" (METOCARD-CNIC): a randomized, controlled parallel-group, observer-blinded clinical trial of early pre-reperfusion metoprolol administration in ST-segmen
    Borja Ibanez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain
    Am Heart J 164:473-480.e5. 2012
    ..To date, there is not a single trial comparing the pre- vs. post-reperfusion β-blocker initiation in STEMI...
  4. doi request reprint Lethal myocardial reperfusion injury: a necessary evil?
    Borja Ibanez
    Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III C N I C, Madrid, Spain
    Int J Cardiol 151:3-11. 2011
    ..Currently, no intervention has been consistently shown to reduce reperfusion injury in large randomized multicenter trials, but the research in this field is intense and the future is highly promising...
  5. doi request reprint [Modulation of the beta-adrenergic system during acute myocardial infarction: rationale for a new clinical trial]
    Borja Ibanez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Espana
    Rev Esp Cardiol 64:28-33. 2011
    ..The Effect of METOprolol in CARDioproteCtioN during an acute myocardial InfarCtion (METOCARD-CNIC) trial will test this hypothesis in patients with ST-segment elevation AMI...
  6. doi request reprint Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Borja Ibanez
    From Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain B I, G P, L F F, A M, A F O, J M G R, A G A, J J B, P L R, R F J, M D R, N E, J G P, D S R, S P, G S, V F Hospital Clínico San Carlos IdISSC, Madrid, Spain B I, C M, A F O, R F J, B R M, C A, J C G R, R H A Servicio de Urgencia Médica de Madrid SUMMA 112, Madrid, Spain V S B, A M, J V, M J F C Hospital Universitario Quirón, Madrid
    Circulation 128:1495-503. 2013
    ..The effect of β-blockers on infarct size when used in conjunction with primary percutaneous coronary intervention is unknown. We hypothesize that metoprolol reduces infarct size when administered early (intravenously before reperfusion)...
  7. doi request reprint Safety and efficacy of intense antithrombotic treatment and percutaneous coronary intervention deferral in patients with large intracoronary thrombus
    Mauro Echavarría-Pinto
    Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain
    Am J Cardiol 111:1745-50. 2013
    ..These benefits were observed without an increase in hemorrhagic complications...
  8. doi request reprint Fractional flow reserve and minimum Pd/Pa ratio during intravenous adenosine infusion: very similar but not always the same
    Mauro Echavarría-Pinto
    Hospital Clinico San Carlos and Centro Nacional de Investigaciónes Cardiovasculares Carlos III CNIC, Madrid, Spain
    EuroIntervention 11:1013-9. 2016
    ..We sought to describe the prevalence, magnitude and clinical implications of this phenomenon...
  9. doi request reprint Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction)
    Gonzalo Pizarro
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Hospital Universitario Quirón Universidad Europea de Madrid, Madrid, Spain
    J Am Coll Cardiol 63:2356-62. 2014
    ..The goal of this trial was to study the long-term effects of intravenous (IV) metoprolol administration before reperfusion on left ventricular (LV) function and clinical events...
  10. doi request reprint Pathophysiology Underlying the Bimodal Edema Phenomenon After Myocardial Ischemia/Reperfusion
    Rodrigo Fernández-Jiménez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Hospital Universitario Clínico San Carlos, Madrid, Spain
    J Am Coll Cardiol 66:816-28. 2015
    ....
  11. doi request reprint Association of myocardial T1-mapping CMR with hemodynamics and RV performance in pulmonary hypertension
    Ana García-Alvarez
    Imaging in Experimental Cardiology Laboratory, Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Epidemiology, Atherothrombosis and Imaging Department, CNIC, Madrid, Spain Hospital Clínic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain Electronic address
    JACC Cardiovasc Imaging 8:76-82. 2015
    ..Eq-ECV values also increased before overt RV systolic dysfunction, offering potential for the early detection of myocardial involvement in chronic PH. ..
  12. doi request reprint Low coronary microcirculatory resistance associated with profound hypotension during intravenous adenosine infusion: implications for the functional assessment of coronary stenoses
    Mauro Echavarría-Pinto
    From the Cardiovascular Institute, Hospital Clínico San Carlos and Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain M E P, B I, A Q, A F O, J E Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain N G, P J Q, F A, I J N G, C B, C M International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom R P, S S, S N, J T, J D and Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea B K K
    Circ Cardiovasc Interv 7:35-42. 2014
    ..However, adenosine-induced hypotension during stable hyperemia is heterogeneous, and its relevance to coronary stenoses assessment with fractional flow reserve (FFR) remains largely unknown...
  13. ncbi request reprint Incomplete myocardial rupture after coronary embolism of an isolated single coronary artery
    Javier Pindado
    Servicio de Cardiologia, Fundacion Jimenez Diaz, Universidad Autonoma, Madrid, Spain
    Eur J Echocardiogr 6:72-4. 2005
    ..She died in cardiogenic shock due to the extensive left ventricular damage...
  14. doi request reprint β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes
    Jaime García-Prieto
    Imaging, Epidemiology and Atherothrombosis Department, Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Melchor Fernandez Almagro 3, 28029, Madrid, Spain
    Basic Res Cardiol 109:422. 2014
    ..This protection appears to be executed through inhibition of mPTP opening in cardiomyocytes. ..
  15. doi request reprint Exercise triggers ARVC phenotype in mice expressing a disease-causing mutated version of human plakophilin-2
    Francisco M Cruz
    Cardiovascular Development and Repair Department, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
    J Am Coll Cardiol 65:1438-50. 2015
    ....
  16. pmc Combination proximal pulmonary artery coiling and distal embolization induces chronic elevations in pulmonary artery pressure in Swine
    Jaume Aguero
    Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC Epidemiology, Atherothrombosis and Imaging Department, Madrid, Spain
    PLoS ONE 10:e0124526. 2015
    ..Taken together, these cardiopulmonary hemodynamic and structural findings identify the novel combination embolization swine model as a valuable tool for future studies of chronic PH. ..
  17. doi request reprint Prehospital activation of cardiac catheterization teams in ST-segment elevation myocardial infarction
    Eduardo Franco
    Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain
    Rev Port Cardiol 33:545-53. 2014
    ..In January 2011, we initiated a new primary angioplasty activation protocol from prehospital locations. Our objective was to quantify the influence of this change on reperfusion times...
  18. pmc Fast T2 gradient-spin-echo (T2-GraSE) mapping for myocardial edema quantification: first in vivo validation in a porcine model of ischemia/reperfusion
    Rodrigo Fernández-Jiménez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain
    J Cardiovasc Magn Reson 17:92. 2015
    ..Our objective was to obtain in vivo validation of a sequence for fast and accurate myocardial T2-mapping (T2 gradient-spin-echo [GraSE]) that can be easily integrated in routine protocols...
  19. doi request reprint Mechanisms of balloon angioplasty and repeat stenting in patients with drug-eluting in-stent restenosis
    Fernando Alfonso
    Hospital Universitario de la Princesa, Madrid, Spain Electronic address
    Int J Cardiol 178:213-20. 2015
    ..Mechanisms of lumen gain during reinterventions in patients with drug-eluting stent (DES) in-stent restenosis (ISR) remain unsettled...
  20. doi request reprint Myocardial edema after ischemia/reperfusion is not stable and follows a bimodal pattern: imaging and histological tissue characterization
    Rodrigo Fernández-Jiménez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Hospital Universitario Clínico San Carlos, Madrid, Spain
    J Am Coll Cardiol 65:315-23. 2015
    ..However, there are no longitudinal studies covering from very early (minutes) to late (1 week) reperfusion stages confirming this phenomenon...
  21. pmc Impact of left ventricular hypertrophy on troponin release during acute myocardial infarction: new insights from a comprehensive translational study
    Rodrigo Fernández-Jiménez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain R F J, S M M, D M, M N A, J M G R, A G, L F F, T G P, J G P, D S R, G M, V F, J M R, B I Hospital Universitario Clínico San Carlos, Madrid, Spain R F J, J S, A F O, C M, B I
    J Am Heart Assoc 4:e001218. 2015
    ..Here, we prospectively studied the impact of left ventricular (LV) hypertrophy (LVH) on biomarker release in clinical and experimental myocardial infarction (MI)...
  22. doi request reprint Prevalence, Vascular Distribution, and Multiterritorial Extent of Subclinical Atherosclerosis in a Middle-Aged Cohort: The PESA (Progression of Early Subclinical Atherosclerosis) Study
    Leticia Fernandez-Friera
    From Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain L F F, J L P, A F O, B I, B L M, M L, B O, L G, J Molina, G G, H S, S P, J M O, G S, L J J B, V F Hospital Universitario Montepríncipe, Madrid, Spain L F F, B L M Universidad Autónoma de Madrid, Spain M L St Louis University, St Louis, MO M L Hospital Clínico San Carlos, Universidad Complutense, Madrid, Spain A F O, B I Banco de Santander, Madrid, Spain A M, J Mendiguren Hospital Universitario Quirón, Madrid, Spain V M d V Philips Healthcare, Madrid, Spain J S G Hospital Universitario La Paz, Madrid, California 94720-3204
    Circulation 131:2104-13. 2015
    ..Data are limited on the presence, distribution, and extent of subclinical atherosclerosis in middle-aged populations...
  23. doi request reprint Swine model of chronic postcapillary pulmonary hypertension with right ventricular remodeling: long-term characterization by cardiac catheterization, magnetic resonance, and pathology
    Daniel Pereda
    Imaging in Experimental Cardiology Laboratory IExC Lab, Epidemiology, Atherothrombosis and Imaging Department, Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Melchor Fernandez Almagro 3, 28029, Madrid, Spain
    J Cardiovasc Transl Res 7:494-506. 2014
    ..Also, remodeling on pulmonary arteries including increased medial and intimal thickness and fibrosis and RV myocardial disarray and fibrosis was demonstrated. Lung remodeling findings were similar in all pulmonary lobes...
  24. doi request reprint Disturbed coronary hemodynamics in vessels with intermediate stenoses evaluated with fractional flow reserve: a combined analysis of epicardial and microcirculatory involvement in ischemic heart disease
    Mauro Echavarría-Pinto
    Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain M E P, J E, E M, M M, N G, P J Q, R H, R M B I, I J N G, F A, C B, E G, A F O, C M Centro Nacional de Investigaciónes Cardiovasculares Carlos III CNIC, Madrid, Spain M E P, J E, B I, A F O Imperial College Healthcare and NHS Trust, London, UK R P, S S, J D and Clinical Epidemiology Unit, Hospital Clinico San Carlos, Madrid, Spain C F
    Circulation 128:2557-66. 2013
    ..The prevalence of these ischemic heart disease levels in fractional flow reserve (FFR) interrogated vessels remains largely unknown...
  25. doi request reprint Tako-tsubo syndrome and heart failure: long-term follow-up
    Iván J Núñez-Gil
    Unidad Coronaria, Cardiología Intervencionista e Imagen Cardiovascular, Instituto Cardiovascular, Hospital Clinico San Carlos, Madrid, Spain
    Rev Esp Cardiol (Engl Ed) 65:996-1002. 2012
    ....
  26. doi request reprint Femoral and Carotid Subclinical Atherosclerosis Association With Risk Factors and Coronary Calcium: The AWHS Study
    Martin Laclaustra
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Centro de Investigación Biomédica en Red Epidemiología y Salud Pública CIBERESP, Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autonoma de Madrid, Madrid, Spain Department of Epidemiology, St Louis University, St Louis, Missouri
    J Am Coll Cardiol 67:1263-74. 2016
    ..Early subclinical atherosclerosis has been mainly researched in carotid arteries. The potential value of femoral arteries for improving the predictive capacity of traditional risk factors is an understudied area...
  27. doi request reprint Induction of sustained hypercholesterolemia by single adeno-associated virus-mediated gene transfer of mutant hPCSK9
    Marta Roche-Molina
    From the Cardiovascular Development and Repair Department M R M, F M C, J A B, and Epidemiology, Atherothrombosis and Imaging Department D S R, J G P, V F, B I, Centro Nacional de Investigaciones Cardiovasculares CNIC, Madrid, Spain Laboratory of Cellular and Molecular Nutrition, Instituto de la Grasa CSIC, Seville, Spain S L, R A, F J G M The Zena and Michael a Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY V F and Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain B I
    Arterioscler Thromb Vasc Biol 35:50-9. 2015
    ....
  28. ncbi request reprint [Tako-tsubo syndrome associated with a long course of the left anterior descending coronary artery along the apical diaphragmatic surface of the left ventricle]
    Borja Ibanez
    Servicio de Cardiologia, Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Madrid, Spain
    Rev Esp Cardiol 57:209-16. 2004
    ..We report one of the first series outside Japan, which provides new information on the coronary anatomy of this disorder...
  29. pmc Optimization of dual-saturation single bolus acquisition for quantitative cardiac perfusion and myocardial blood flow maps
    Javier Sánchez-Gonzalez
    Philips Healthcare Iberia, Maria de Portugal 1 28050, Madrid, Spain
    J Cardiovasc Magn Reson 17:21. 2015
    ..Dual-saturation acquisition also lacks a clinically-applicable procedure for optimizing parameter selection. Here we present a comprehensive validation study of dual-saturation strategy in vitro and in vivo...
  30. doi request reprint Metabolomics reveals metabolite changes in acute pulmonary embolism
    Renata Bujak
    Centre for Metabolomics and Bioanalysis CEMBIO, Facultad de Farmacia, Universidad CEU San Pablo, Campus Monteprincipe, Boadilla del Monte 28668, Madrid, Spain
    J Proteome Res 13:805-16. 2014
    ..Results presented in this report reveal that combination of LC-MS- and GC-MS-based metabolomics could be a powerful tool for diagnosis and understanding pathophysiological processes due to acute PE. ..
  31. doi request reprint Safety of lone thrombus aspiration without concomitant coronary stenting in selected patients with acute myocardial infarction
    Javier Escaned
    Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain
    EuroIntervention 8:1149-56. 2013
    ..We present our experience in a cohort of patients with STEMI treated only with TA, without concomitant interventional devices...
  32. doi request reprint Circadian variations of infarct size in acute myocardial infarction
    Aida Suárez-Barrientos
    Coronary Care Unit, Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain
    Heart 97:970-6. 2011
    ..A circadian variation in infarct size has recently been shown in rodents, but there is no clinical evidence of this finding...
  33. doi request reprint Imaging subclinical atherosclerosis: is it ready for prime time? A review
    Leticia Fernandez-Friera
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain
    J Cardiovasc Transl Res 7:623-34. 2014
    ..Noninvasive imaging will also help to identify individuals at high CV who would benefit from intensive prevention or therapeutic interventions. ..
  34. doi request reprint Imagining the future of diagnostic imaging
    Leticia Fernandez-Friera
    Centro Nacional de Investigaciones Cardiovasculares CNIC Imaging in Experimental Cardiology Laboratory IExC Lab, Madrid, Spain Servicio de Cardiología, Hospital Universitario Montepríncipe, Madrid, Spain
    Rev Esp Cardiol (Engl Ed) 66:134-43. 2013
    ....
  35. doi request reprint The Progression and Early detection of Subclinical Atherosclerosis (PESA) study: rationale and design
    Antonio Fernandez-Ortiz
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain Hospital Clínico San Carlos, Madrid, Spain
    Am Heart J 166:990-8. 2013
    ..The presence of subclinical atherosclerosis is a likely predictor of cardiovascular events; however, factors associated with the early stages and progression of atherosclerosis are poorly defined...
  36. doi request reprint The future: therapy of myocardial protection
    David Sanz-Rosa
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain
    Ann N Y Acad Sci 1254:90-8. 2012
    ..The demonstration of such a cardioprotective effect should have a significant impact in the care of AMI patients...
  37. doi request reprint Recombinant HDL(Milano) exerts greater anti-inflammatory and plaque stabilizing properties than HDL(wild-type)
    Borja Ibanez
    Atherothrombosis Research Unit, The Zena and Michael A Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    Atherosclerosis 220:72-7. 2012
    ..The aim of this study was to compare the effects of HDL(Milano) and HDL(wild-type), on regression and stabilization of atherosclerosis...
  38. doi request reprint Systemic fibrinolysis through intraosseous vascular access in ST-segment elevation myocardial infarction
    Pedro José Ruiz-Hornillos
    Servicio de Asistencia Municipal de Urgencia y Rescate, Madrid, Spain
    Ann Emerg Med 57:572-4. 2011
    ..Intraosseous cannulation represents a novel route for administration of systemic fibrinolysis in cases of difficult peripheral venous access in the out-of-hospital setting...
  39. doi request reprint Combining Baseline Distal-to-Aortic Pressure Ratio and Fractional Flow Reserve in the Assessment of Coronary Stenosis Severity
    Mauro Echavarría-Pinto
    Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain AMC Heart Centre, Academic Medical Centre University of Amsterdam, Amsterdam, The Netherlands Electronic address
    JACC Cardiovasc Interv 8:1681-91. 2015
    ....
  40. pmc Characterization of right ventricular remodeling and failure in a chronic pulmonary hypertension model
    Jaume Aguero
    Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York Centro Nacional de Investigaciones Cardiovasculares Carlos III Epidemiology, Atherothrombosis and Imaging Department, Madrid, Spain
    Am J Physiol Heart Circ Physiol 307:H1204-15. 2014
    ..Diastolic dysfunction and fibrosis are present in adaptive RV remodeling, whereas the onset of RV failure is associated with RV-PA uncoupling, defective calcium handling, and hyperaldosteronism. ..
  41. doi request reprint Health and cost benefits associated with the use of metoprolol in heart attack patients
    Rodrigo Fernández-Jiménez
    Department of Atherothrombosis, Imaging and Epidemiology, Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Melchor Fernandez Almagro, 3 28029, Madrid, Spain
    Expert Rev Clin Pharmacol 7:687-9. 2014
    ..If confirmed in larger trials, this low-cost therapy is expected to have a major health and socioeconomic impact. ..
  42. doi request reprint Noninvasive monitoring of serial changes in pulmonary vascular resistance and acute vasodilator testing using cardiac magnetic resonance
    Ana García-Alvarez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC Imaging in Experimental Cardiology Laboratory IExC Lab, Madrid, Spain Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC Epidemiology, Atherothrombosis and Imaging Department, Madrid, Spain Hospital Clínic, IDIBAPS, Barcelona, Spain
    J Am Coll Cardiol 62:1621-31. 2013
    ..The study sought to evaluate the ability of cardiac magnetic resonance (CMR) to monitor acute and long-term changes in pulmonary vascular resistance (PVR) noninvasively...