Joaquim Casellas

Summary

Affiliation: Centre UdL-IRTA
Country: Spain

Publications

  1. ncbi Using haplotype probabilities in categorical survival analysis: a case study with three candidate genes in an Iberian x Meishan F2 population of newborn piglets
    J Casellas
    Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, Barcelona, Spain
    J Anim Breed Genet 125:5-12. 2008
  2. ncbi Bayesian inference in a piecewise Weibull proportional hazards model with unknown change points
    J Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Anim Breed Genet 124:176-84. 2007
  3. pmc Survival quantitative trait locus fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium
    J Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Genetics 176:721-4. 2007
  4. pmc Bayes factor between Student t and Gaussian mixed models within an animal breeding context
    Joaquim Casellas
    Genetica i Millora Animal, IRTA Lleida, 25198 Lleida, Spain
    Genet Sel Evol 40:395-413. 2008
  5. pmc Between-groups within-gene heterogeneity of residual variances in microarray gene expression data
    Joaquim Casellas
    Genetica i Millora Animal, IRTA Lleida, 25198 Lleida, Spain
    BMC Genomics 9:319. 2008
  6. ncbi Analysis of founder-specific inbreeding depression on birth weight in Ripollesa lambs
    J Casellas
    Genetica i Millora Animal, Institut de Recerca i Tecnologia Agroalimentaries Lleida, 25198 Lleida, Spain
    J Anim Sci 87:72-9. 2009
  7. ncbi GEAMM v.1.4: a versatile program for mixed model analysis of gene expression data
    J Casellas
    Genetica i Millora Animal, IRTA Lleida, 25198 Lleida, Spain
    Anim Genet 39:89-90. 2008
  8. pmc Evidence of maternal QTL affecting growth and obesity in adult mice
    Joaquim Casellas
    Animal Breeding and Genetics, IRTA Lleida, Lleida, Spain
    Mamm Genome 20:269-80. 2009
  9. pmc Genome scans for transmission ratio distortion regions in mice
    Joaquim Casellas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    Genetics 191:247-59. 2012
  10. ncbi Viability of Iberian x Meishan F2 newborn pigs. II. Survival analysis up to weaning
    J Casellas
    Department de Ciència Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Anim Sci 82:1925-30. 2004

Detail Information

Publications38

  1. ncbi Using haplotype probabilities in categorical survival analysis: a case study with three candidate genes in an Iberian x Meishan F2 population of newborn piglets
    J Casellas
    Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, Barcelona, Spain
    J Anim Breed Genet 125:5-12. 2008
    ..770 (CI = 0.606 to 0.977; p < 0.05). Although further researches are required, BMPR1B and DBH genes could be a useful tool to improve piglet survival under a marker assisted selection strategy...
  2. ncbi Bayesian inference in a piecewise Weibull proportional hazards model with unknown change points
    J Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Anim Breed Genet 124:176-84. 2007
    ..Moreover, results showed that the piecewise baseline hazard function could appropriately fit survival data, as well as other smooth distributions, with a reduced number of change points...
  3. pmc Survival quantitative trait locus fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium
    J Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Genetics 176:721-4. 2007
    ..The method is based on chi(2)-tests and they can be performed for age-specific samples of alive (or dead) individuals, as for combined samples of alive and dead individuals...
  4. pmc Bayes factor between Student t and Gaussian mixed models within an animal breeding context
    Joaquim Casellas
    Genetica i Millora Animal, IRTA Lleida, 25198 Lleida, Spain
    Genet Sel Evol 40:395-413. 2008
    ..For the analysis of real data (weight of Pietrain pigs at six months), both the Bayes factor and DIC slightly favored the Student t mixed model, with there being a reduced incidence of outlier individuals in this population...
  5. pmc Between-groups within-gene heterogeneity of residual variances in microarray gene expression data
    Joaquim Casellas
    Genetica i Millora Animal, IRTA Lleida, 25198 Lleida, Spain
    BMC Genomics 9:319. 2008
    ..Commonly, a homogeneous gene-specific residual variance is assumed in hierarchical mixed models for gene expression data, although it could result in substantial biases if this assumption is not true...
  6. ncbi Analysis of founder-specific inbreeding depression on birth weight in Ripollesa lambs
    J Casellas
    Genetica i Millora Animal, Institut de Recerca i Tecnologia Agroalimentaries Lleida, 25198 Lleida, Spain
    J Anim Sci 87:72-9. 2009
    ..These results contribute valuable information that should help to achieve more accurate management of inbreeding in the Ripollesa breed...
  7. ncbi GEAMM v.1.4: a versatile program for mixed model analysis of gene expression data
    J Casellas
    Genetica i Millora Animal, IRTA Lleida, 25198 Lleida, Spain
    Anim Genet 39:89-90. 2008
  8. pmc Evidence of maternal QTL affecting growth and obesity in adult mice
    Joaquim Casellas
    Animal Breeding and Genetics, IRTA Lleida, Lleida, Spain
    Mamm Genome 20:269-80. 2009
    ....
  9. pmc Genome scans for transmission ratio distortion regions in mice
    Joaquim Casellas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    Genetics 191:247-59. 2012
    ....
  10. ncbi Viability of Iberian x Meishan F2 newborn pigs. II. Survival analysis up to weaning
    J Casellas
    Department de Ciència Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Anim Sci 82:1925-30. 2004
    ..The genetic variance was small compared with those generated by the common environment, for which the genetic improvement of piglet survival seems difficult...
  11. ncbi Genetic and environmental factors influencing mortality up to weaning of Bruna dels Pirineus beef calves in mountain areas. A survival analysis
    J Tarres
    Grup de Recerca en Remugants, Departament de Ciència Animals i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Anim Sci 83:543-51. 2005
    ..Overall, these results show that survival analysis is a powerful tool to analyze the mortality curve until weaning of beef calves...
  12. pmc Segregation analysis of a sex ratio distortion locus in congenic mice
    Joaquim Casellas
    Genetica i Millora Animal, Institut de Recerca i Tecnologia Agroalimentaries Lleida, Lleida, Spain
    J Hered 101:351-9. 2010
    ..3% to 14.4%, respectively. This article provides significant evidence of genetic determinism for sex ratio distortion in the HQ17(hg)(/hg) strain and develops new analytical tools to perform segregation studies on dichotomous traits...
  13. ncbi Skew distribution of founder-specific inbreeding depression effects on the longevity of Landrace sows
    J Casellas
    Genetica i Millora Animal, IRTA Lleida, Alcalde Rovira Roure, 191, 25198 Lleida, Spain
    Genet Res (Camb) 90:499-508. 2008
    ....
  14. ncbi Polymorphisms of the porcine dopamine beta-hydroxylase gene and their relation to reproduction and piglet survivability in an Iberian x Meishan F2 intercross
    A Tomas
    Departament de Ciencia Animal i dels Aliments, Facultat de Veterinaria, UAB, Bellaterra 08193, Spain
    Anim Genet 37:279-82. 2006
    ..The DBH haplotypes significantly affected rectal temperatures 1 h after birth (P = 0.002) and have a suggestive effect on the time to first colostrum intake (P = 0.019) and on birth weight (P = 0.019)...
  15. ncbi Epistasis for founder-specific inbreeding depression in rabbits
    Joaquim Casellas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Spain
    J Hered 102:157-64. 2011
    ..9 and -1.0 g reduction on WW. These results provide the first evidence of epistatic inbreeding depression phenomena in domestic species, emphasizing the complexity of the genetic architecture in mammals...
  16. pmc Bayes factor for testing between different structures of random genetic groups: a case study using weaning weight in Bruna dels Pirineus beef cattle
    Joaquim Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Genet Sel Evol 39:39-53. 2007
    ....
  17. ncbi Viability of Iberian x Meishan F2 newborn pigs. I. Analysis of physiological and vitality variables
    J Casellas
    Department de Ciència Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Anim Sci 82:1919-24. 2004
    ..The recording of physiological variables, birth weight, and viability score may be useful to identify weak piglets quickly and to establish palliative measures...
  18. ncbi Bayesian analysis of quantitative traits using skewed distributions
    L Varona
    Genetica i Millora Animal, IRTA Lleida, Av Rovira Roure 191, 25198 Lleida, Spain
    Genet Res (Camb) 90:179-90. 2008
    ..28 (0.06) for litter size and 0.07 (0.01) for the asymmetry parameter. The posterior mean (standard deviation) of the additive genetic correlation between litter size and the asymmetry parameter was 0.21 (0.07)...
  19. ncbi Accounting for additive genetic mutations on litter size in Ripollesa sheep
    J Casellas
    Genetica i Millora Animal, Institut de Recerca i Tecnologia Agroalimentaries Lleida, 25198 Lleida, Spain
    J Anim Sci 88:1248-55. 2010
    ..This study is the first attempt to estimate mutational variances in a livestock species and thereby contribute to better characterization of the genetic background of productive traits of interest...
  20. ncbi Survival analysis from birth to slaughter of Ripollesa lambs under semi-intensive management
    J Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    J Anim Sci 85:512-7. 2007
    ..61; P < 0.05). The variance component estimated for sire variance (0.07) was clearly lower than that of the common environment (1.87), with a heritability estimate of 0.027...
  21. ncbi Bayes factor analysis for the genetic background of physiological and vitality variables of F2 Iberian x Meishan newborn piglets
    L Varona
    Area de Produccio Animal, Centre UdL IRTA, 25198 Lleida, Spain
    J Anim Sci 83:334-9. 2005
    ..82). Posterior modes (means) of heritabilities were 0.29 (0.32) and 0.40 (0.39), respectively. In addition, substantial evidence of absence of genetic background was detected for arterial oxygen saturation at birth...
  22. ncbi Short communication: Accounting for new mutations in genomic prediction models
    Joaquim Casellas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    J Dairy Sci 96:5398-402. 2013
    ....
  23. ncbi Effect of medium- and long-chain triglyceride supplementation on small newborn-pig survival
    J Casellas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Prev Vet Med 67:213-21. 2005
    ..8, and the HR for litters with >12 piglets born alive was 4.5. There was variation across months, and also piglets from primiparous sows had increased hazard of death (HR=4.0)...
  24. ncbi Bayes factor for testing the genetic background of quantitative threshold traits
    J Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    J Anim Breed Genet 123:301-6. 2006
    ..The method was tested by computer simulations with satisfactory results...
  25. ncbi Parametric bootstrap for testing model fitting in the proportional hazards framework: an application to the survival analysis of Bruna dels Pirineus beef calves
    J Casellas
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Anim Sci 84:2609-16. 2006
    ..Results here highlighted the flexibility of parametric models with time-dependent effects, achieving a fit comparable to nonparametric models...
  26. ncbi An association analysis between a silent C558T polymorphism at the pig vascular cell adhesion molecule 1 locus and sow reproduction and piglet survivability traits
    O Ramirez
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Barcelona, Spain
    Reprod Domest Anim 43:542-6. 2008
    ..013) as well as a significant one with time to make the first ingestion of colostrum (p = 0.003). The biological basis of these associations remains unclear and they should be interpreted with caution...
  27. pmc Modeling skewness in human transcriptomes
    Joaquim Casellas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Spain
    PLoS ONE 7:e38919. 2012
    ..The source code of the program accommodating these analytical developments and additional information about practical aspects on running the program are freely available by request to the corresponding author of this article...
  28. pmc Within-generation mutation variance for litter size in inbred mice
    Joaquim Casellas
    Genetica i Millora Animal, Institut de Recerca i Tecnologia Agroalimentaries Lleida, Lleida, Spain
    Genetics 179:2147-55. 2008
    ....
  29. ncbi An association study between polymorphisms of the porcine bone morphogenetic protein receptor type1beta(BMPR1B) and reproductive performance of Iberian x Meishan F2 sows
    A Tomas
    Departament de Ciencia Animal i dels Aliments, Facultat de Veterinaria, UAB, Bellaterra 08193, Spain
    Anim Genet 37:297-8. 2006
  30. ncbi Bayesian threshold analysis of direct and maternal genetic parameters for piglet mortality at farrowing in Large White, Landrace, and Pietrain populations
    N Ibáñez-Escriche
    Genetica i Millora Animal, Institut de Recerca i Tecnologia Agroalimentaries Lleida, 25198 Lleida, Spain
    J Anim Sci 87:80-7. 2009
    ....
  31. ncbi Analysis of litter size and days to lambing in the Ripollesa ewe. I. Comparison of models with linear and threshold approaches
    J Casellas
    Grup de Recerca en Remugants, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    J Anim Sci 85:618-24. 2007
    ..For the purpose of genetic evaluation of litter size in sheep, use of the threshold-linear model seems justified. In the Ripollesa breed, the evaluation of litter size can benefit from recording birth weight...
  32. ncbi High amino acid variation in the intracellular domain of the pig prolactin receptor (PRLR) and its relation to ovulation rate and piglet survival traits
    A Tomas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Anim Sci 84:1991-8. 2006
    ....
  33. ncbi Bayes factor analyses of heritability for serum and muscle lipid traits in Duroc pigs
    J Casellas
    Genetica i Millora Animal, Institut de Recerca i Tecnologia Agroalimentàries IRTA Lleida, 25198 Lleida, Spain
    J Anim Sci 88:2246-54. 2010
    ..As a whole, these results confirm the complexity of lipid metabolism in pigs...
  34. ncbi Bayesian analysis of additive epistasis arising from new mutations in mice
    Joaquim Casellas
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Genet Res (Camb) 96:e008. 2014
    ..These results contribute new insights on the relevance of epistasis in the genetic architecture of mammals and serve as an important component of an additional source of genetic heterogeneity for inbred strains of laboratory mice. ..
  35. pmc Lack of Socs2 expression reduces lifespan in high-growth mice
    Joaquim Casellas
    , IRTA Lleida, 25198, Lleida, Spain
    Age (Dordr) 30:245-9. 2008
    ..This result is consistent with previous research in dwarf mutant mice and other species, and characterizes the HG mutant mice as a unique and interesting animal model for accelerated aging research...
  36. ncbi Analysis of litter size and days to lambing in the Ripollesa ewe. II. Estimation of variance components and response to phenotypic selection on litter size
    J Casellas
    Grup de Recerca en Remugants, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Anim Sci 85:625-31. 2007
    ..Results indicated that litter size in sheep can be effectively improved through phenotypic selection, even in small flocks; moreover, days to lambing could also be genetically improved, given the estimate obtained for its heritability...
  37. ncbi Association analyses between the prion protein locus and reproductive and lamb weight traits in Ripollesa sheep
    J Casellas
    Grup de Recerca en Remugants, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Anim Sci 85:592-7. 2007
    ..As a consequence, scrapie genotyping needs to be included as a new selection criterion in the breed...
  38. ncbi Retention of different sizes of electronic identification boluses in the forestomachs of sheep
    J J Ghirardi
    Grup de Recerca en Remugants, Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Spain
    J Anim Sci 84:2865-72. 2006
    ..For safe and efficient retention of electronic identification boluses in sheep, boluses of small volume and diameter (e.g., < 15 mm) with specific gravity and weight greater than 3.0 and 20 g, respectively, are recommended...