Avy Violari

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. pmc Early antiretroviral therapy and mortality among HIV-infected infants
    Avy Violari
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    N Engl J Med 359:2233-44. 2008
  2. pmc Early Antiretroviral Therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy: Evidence from the Children with HIV Early Antiretroviral Therapy (CHER) Study
    Clotilde Hainline
    Department of Paediatrics and Child Health and Children s Infectious Diseases Clinical Research Unit KID CRU, Tygerberg Children s Hospital and Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa
    BMC Res Notes 4:448. 2011
  3. pmc Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study
    Heather B Jaspan
    Children s Infectious Diseases Clinical Research Unit, Department of Paediatrics and Child Health and Centre for Infectious Diseases, Stellenbosch University, Tygerberg, South Africa
    BMC Pediatr 11:104. 2011
  4. pmc Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization
    Shabir A Madhi
    University of the Witwatersrand, Department of Science and Technology National Research Foundation Vaccine Preventable Diseases and Respiratory and Meningeal Pathogens Research Unit, Johannesburg, South Africa
    Vaccine 29:6994-7001. 2011
  5. pmc Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children
    Avy Violari
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    N Engl J Med 366:2380-9. 2012
  6. pmc Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants
    Shabir A Madhi
    Department of Science National Research Foundation, Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa
    J Infect Dis 202:355-61. 2010
  7. pmc Primary isoniazid prophylaxis against tuberculosis in HIV-exposed children
    Shabir A Madhi
    Department of Science and Technology National Research Foundation Vaccine Preventable Diseases and the Medical Research Council Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    N Engl J Med 365:21-31. 2011
  8. pmc Predictors of virologic and clinical response to nevirapine versus lopinavir/ritonavir-based antiretroviral therapy in young children with and without prior nevirapine exposure for the prevention of mother-to-child HIV transmission
    Jane C Lindsey
    From the Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA University of Witwatersrand, Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, Johannesburg, South Africa Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD Department of Epidemiology, ICAP, Mailman School of Public Health and College of Physicians and Surgeons, Columbia University, New York, NY Department of Paediatrics and Child Health, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe Makerere University Johns Hopkins University Research Collaboration, Kampala, Uganda University of North Carolina Project, Lilongwe, Malawi University Teaching Hospital, Lusaka, Zambia Division of Paediatrics and Infectious Diseases, Tygerberg Children s Hospital, Stellenbosch University, Tygerberg University of the Witwatersrand Reproductive Health and HIV Institute, Faculty of Health Sciences, Johannesburg, South Africa Department of Pediatrics, BJ Medical College and Sassoon General Hospital, Pune, India Duke University Kilimanjaro Christian Medical Center Collaboration, Moshi, Tanzania Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Frontier Science and Technology Research Foundation, USA
    Pediatr Infect Dis J 33:846-54. 2014
  9. ncbi request reprint Combining PMTCT with active case finding for tuberculosis
    Paula B N Kali
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 42:379-81. 2006
  10. pmc Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention
    Mary G Fowler
    From the Department of Pathology, Johns Hopkins University School of Medicine M G F, and the Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health T E T, Baltimore, and the Division of AIDS, National Institute of Allergy and Infectious Diseases D G, K L K, R Browning, L P, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development G K S, National Institutes of Health, Bethesda all in Maryland the Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston M Q, T F, D E S the Retrovirology Core Laboratory, University of North Carolina School of Medicine, Chapel Hill S A F, A J L, and FHI 360, Durham A S C both in North Carolina the UCLA Center for Clinical AIDS Research and Education, Los Angeles J S C St Jude Children s Research Hospital, Memphis, TN P M F the Department of Obstetrics and Gynecology, College of Health Sciences, University of Zimbabwe, Harare T C Anova Health Institute J M, Perinatal HIV Research Unit, University of the Witwatersrand, Faculty of Health Sciences A V, and Empilweni Services and Research Unit R S, Johannesburg, School of Public Health and Family Medicine, University of Cape Town J M, and the Department of Obstetrics and Gynaecology
    N Engl J Med 375:1726-1737. 2016

Collaborators

Detail Information

Publications19

  1. pmc Early antiretroviral therapy and mortality among HIV-infected infants
    Avy Violari
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    N Engl J Med 359:2233-44. 2008
    ..We investigated antiretroviral-treatment strategies in the Children with HIV Early Antiretroviral Therapy (CHER) trial...
  2. pmc Early Antiretroviral Therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy: Evidence from the Children with HIV Early Antiretroviral Therapy (CHER) Study
    Clotilde Hainline
    Department of Paediatrics and Child Health and Children s Infectious Diseases Clinical Research Unit KID CRU, Tygerberg Children s Hospital and Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa
    BMC Res Notes 4:448. 2011
    ..Medical records from one study site were reviewed for otorrhea...
  3. pmc Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study
    Heather B Jaspan
    Children s Infectious Diseases Clinical Research Unit, Department of Paediatrics and Child Health and Centre for Infectious Diseases, Stellenbosch University, Tygerberg, South Africa
    BMC Pediatr 11:104. 2011
    ..Receiver Operating Characteristic (ROC) curves were compiled using combinations of clinical findings...
  4. pmc Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization
    Shabir A Madhi
    University of the Witwatersrand, Department of Science and Technology National Research Foundation Vaccine Preventable Diseases and Respiratory and Meningeal Pathogens Research Unit, Johannesburg, South Africa
    Vaccine 29:6994-7001. 2011
    ....
  5. pmc Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children
    Avy Violari
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    N Engl J Med 366:2380-9. 2012
    ..Regardless of whether there has been prior exposure to nevirapine, the performance of nevirapine versus ritonavir-boosted lopinavir in young children has not been rigorously established...
  6. pmc Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants
    Shabir A Madhi
    Department of Science National Research Foundation, Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa
    J Infect Dis 202:355-61. 2010
    ..Nevertheless, M-/I- infants had superior OPA responses, compared with those in HIV+/ART+ infants, who in turn had better OPA responses, compared with those in HIV+/ART- infants...
  7. pmc Primary isoniazid prophylaxis against tuberculosis in HIV-exposed children
    Shabir A Madhi
    Department of Science and Technology National Research Foundation Vaccine Preventable Diseases and the Medical Research Council Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    N Engl J Med 365:21-31. 2011
    ..We conducted a double-blind, randomized, placebo-controlled trial of preexposure isoniazid prophylaxis against tuberculosis in HIV-infected children and uninfected children exposed to HIV during the perinatal period...
  8. pmc Predictors of virologic and clinical response to nevirapine versus lopinavir/ritonavir-based antiretroviral therapy in young children with and without prior nevirapine exposure for the prevention of mother-to-child HIV transmission
    Jane C Lindsey
    From the Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA University of Witwatersrand, Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, Johannesburg, South Africa Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD Department of Epidemiology, ICAP, Mailman School of Public Health and College of Physicians and Surgeons, Columbia University, New York, NY Department of Paediatrics and Child Health, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe Makerere University Johns Hopkins University Research Collaboration, Kampala, Uganda University of North Carolina Project, Lilongwe, Malawi University Teaching Hospital, Lusaka, Zambia Division of Paediatrics and Infectious Diseases, Tygerberg Children s Hospital, Stellenbosch University, Tygerberg University of the Witwatersrand Reproductive Health and HIV Institute, Faculty of Health Sciences, Johannesburg, South Africa Department of Pediatrics, BJ Medical College and Sassoon General Hospital, Pune, India Duke University Kilimanjaro Christian Medical Center Collaboration, Moshi, Tanzania Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Frontier Science and Technology Research Foundation, USA
    Pediatr Infect Dis J 33:846-54. 2014
    ....
  9. ncbi request reprint Combining PMTCT with active case finding for tuberculosis
    Paula B N Kali
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 42:379-81. 2006
    ..We conclude that rates of TB in HIV-infected pregnant women are high, and screening for TB during routine antenatal care should be implemented in high HIV-prevalence settings...
  10. pmc Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention
    Mary G Fowler
    From the Department of Pathology, Johns Hopkins University School of Medicine M G F, and the Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health T E T, Baltimore, and the Division of AIDS, National Institute of Allergy and Infectious Diseases D G, K L K, R Browning, L P, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development G K S, National Institutes of Health, Bethesda all in Maryland the Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston M Q, T F, D E S the Retrovirology Core Laboratory, University of North Carolina School of Medicine, Chapel Hill S A F, A J L, and FHI 360, Durham A S C both in North Carolina the UCLA Center for Clinical AIDS Research and Education, Los Angeles J S C St Jude Children s Research Hospital, Memphis, TN P M F the Department of Obstetrics and Gynecology, College of Health Sciences, University of Zimbabwe, Harare T C Anova Health Institute J M, Perinatal HIV Research Unit, University of the Witwatersrand, Faculty of Health Sciences A V, and Empilweni Services and Research Unit R S, Johannesburg, School of Public Health and Family Medicine, University of Cape Town J M, and the Department of Obstetrics and Gynaecology
    N Engl J Med 375:1726-1737. 2016
    ..Funded by the National Institutes of Health; PROMISE ClinicalTrials.gov numbers, NCT01061151 and NCT01253538 .)...
  11. ncbi request reprint Genotypic and phenotypic characterization of viral isolates from HIV-1 subtype C-infected children with slow and rapid disease progression
    Isaac Choge
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    AIDS Res Hum Retroviruses 22:458-65. 2006
    ..Similar to adults, CXCR4 usage was uncommon among HIV-1 subtype C isolates from pediatric infections...
  12. ncbi request reprint A randomized trial of two postexposure prophylaxis regimens to reduce mother-to-child HIV-1 transmission in infants of untreated mothers
    Glenda E Gray
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg South Africa
    AIDS 19:1289-97. 2005
    ..Where women do not access antenatal care or HIV testing, postexposure prophylaxis to the infant may be an important preventative strategy...
  13. doi request reprint Temporal Changes in Pneumococcal Colonization in HIV-infected and HIV-uninfected Mother-Child Pairs Following Transitioning From 7-valent to 13-valent Pneumococcal Conjugate Vaccine, Soweto, South Africa
    Susan A Nzenze
    Medical Research Council Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand Department of Science and Technology National Research Foundation Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg
    J Infect Dis 212:1082-92. 2015
    ..We investigated the impact of infant pneumococcal conjugate vaccine (PCV) immunization on pneumococcal colonization among human immunodeficiency virus (HIV)-infected and HIV-uninfected mother-child pairs...
  14. doi request reprint Influenza vaccination of pregnant women and protection of their infants
    Shabir A Madhi
    From the Medical Research Council, Respiratory and Meningeal Pathogens Research Unit S A M, C L C, L K, A H, S J, P V A, N N, K P K, M C N, the Department of Science and Technology National Research Foundation, Vaccine Preventable Diseases S A M, C L C, L K, A H, S J, P V A, N N, M C N, and the Perinatal HIV Research Unit A V, University of the Witwatersrand, the National Institute for Communicable Diseases, the National Health Laboratory Service, Centre for Vaccines and Immunology S A M, F T, M V, Johannesburg, and the Department of Medical Virology, University of Pretoria, Pretoria M V all in South Africa the School of Medicine and Children s Hospital, University of Colorado A W, The Department of Pediatrics, Medicine and Pathology, Germany
    N Engl J Med 371:918-31. 2014
    ..There are limited data on the efficacy of vaccination against confirmed influenza in pregnant women with and those without human immunodeficiency virus (HIV) infection and protection of their infants...
  15. pmc Promoting safe infant feeding practices - the importance of structural, social and contextual factors in Southern Africa
    Ray Lazarus
    Perinatal HIV Research Unit, University of the Witwatersrand Chris Hani Baragwanath Hospital, Soweto, South Africa
    J Int AIDS Soc 16:18037. 2013
    ..This commentary highlights structural, social and contextual barriers to effective implementation of the guidelines and suggests ways to address some of these barriers...
  16. doi request reprint Effect of HIV-1 exposure and antiretroviral treatment strategies in HIV-infected children on immunogenicity of vaccines during infancy
    Omphile E Simani
    aDepartment of Science and Technology National Research Foundation Vaccine Preventable Diseases Johannesburg bMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty Health Sciences University of the Witwatersrand, Faculty of Health Sciences, Johannesburg cPerinatal HIV Research Unit, University of the Witwatersrand, Faculty of Health Sciences dStellenbosch University, Children s Infectious Diseases Clinical Research Unit, Tygerberg eDivision of National Health Laboratory Service, National Institute for Communicable Diseases, Centre for Vaccines and Immunology, Sandringham, South Africa
    AIDS 28:531-41. 2014
    ....
  17. doi request reprint Second and Third Line Antiretroviral Therapy for Children and Adolescents: A Scoping Review
    Erica Lazarus
    1 Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa 2 FAMCRU, Children s Infectious Diseases Clinical Research Unit, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa 3 World Health Organization, HIV Department, Treatment and Care Unit, Geneva, Switzerland 4 Centre for Evidence based Health Care, Department of Interdisciplinary Health, Faculty of Medicine and Health Sciences, Stellenbosch University
    Pediatr Infect Dis J . 2016
    ..We performed an in-depth scoping review of all available literature on second and subsequent line ART regimens in children younger than 18 years...
  18. pmc Single Genome Analysis for the Detection of Linked Multiclass Drug Resistance Mutations in HIV-1-Infected Children After Failure of Protease Inhibitor-Based First-Line Therapy
    Camille Marie Lange
    Division of Infection and Immunity, University College London, London United Kingdom Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Children s Infectious Diseases Clinical Research Unit, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom HJF DAIDS, a Division of the Henry M Jackson Foundation for the Advancement of Military Medicine Inc, Contractor, NIAID, NIH, Department of Health and Human Services, Bethesda, MD Anova Health Institute, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa and Africa Centre for Health and Population Studies, University of KwaZulu Natal
    J Acquir Immune Defic Syndr 69:138-44. 2015
    ..These observations highlight a future therapeutic challenge for vertically infected children where antiretroviral drug classes are limited. ..
  19. doi request reprint Prospective cohort study comparing seasonal and H1N1(2009) pandemic influenza virus illnesses in HIV-infected children during 2009
    Shabir A Madhi
    University of the Witwatersrand, Johannesburg, South Africa
    Pediatr Infect Dis J 33:174-6. 2014
    ..7 vs. 0.2 per 100 child-weeks, respectively; P = 0.0001), and the clinical presentations were similar. Illnesses due to seasonal and A(H1N1p)2009 influenza were self-limiting without neuraminidase inhibitor therapy. ..