Quarraisha Abdool Karim

Summary

Affiliation: University of KwaZulu-Natal
Country: South Africa

Publications

  1. doi request reprint Empowering women in human immunodeficiency virus prevention
    Quarraisha Abdool Karim
    Department of Epidemiology, Columbia University, New York, USA
    Best Pract Res Clin Obstet Gynaecol 26:487-93. 2012
  2. doi request reprint Topical microbicides--what's new?
    Quarraisha Abdool Karim
    CAPRISA Centre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, University of KwaZulu Natal, South Africa
    J Acquir Immune Defic Syndr 63:S144-9. 2013
  3. doi request reprint The global HIV epidemic: current status and challenges
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Curr HIV/AIDS Rep 10:111-2. 2013
  4. doi request reprint Microbicides for the prevention of sexually transmitted HIV infection
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, University of KwaZulu Natal, South Africa
    Expert Rev Anti Infect Ther 11:13-23. 2013
  5. pmc Gender-sensitive reporting in medical research
    Shirin Heidari
    International AIDS Society, Geneva, Switzerland
    J Int AIDS Soc 15:11. 2012
  6. pmc HIV prevalence among high school learners - opportunities for schools-based HIV testing programmes and sexual reproductive health services
    Ayesha B M Kharsany
    Centre for the AIDS Programme of Research in South Africa CAPRISA, 2nd Floor, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag 7, Congella, Durban 4013, South Africa
    BMC Public Health 12:231. 2012
  7. pmc Time for gender mainstreaming in editorial policies
    Shirin Heidari
    Journal of the International AIDS Society, 1216 Cointrin, Geneva, Switzerland
    J Int AIDS Soc 14:11. 2011
  8. pmc Preventing HIV infection in women: a global health imperative
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Clin Infect Dis 50:S122-9. 2010
  9. pmc Integration of antiretroviral therapy with tuberculosis treatment
    Salim S Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, Durban, South Africa
    N Engl J Med 365:1492-501. 2011
  10. pmc Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Trials 12:67. 2011

Collaborators

Detail Information

Publications42

  1. doi request reprint Empowering women in human immunodeficiency virus prevention
    Quarraisha Abdool Karim
    Department of Epidemiology, Columbia University, New York, USA
    Best Pract Res Clin Obstet Gynaecol 26:487-93. 2012
    ..Women are key to turning the tide of the HIV pandemic. Microbicides provide an opportunity to ensure survival of women while addressing the power disparities that underpin women's vulnerability to HIV...
  2. doi request reprint Topical microbicides--what's new?
    Quarraisha Abdool Karim
    CAPRISA Centre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, University of KwaZulu Natal, South Africa
    J Acquir Immune Defic Syndr 63:S144-9. 2013
    ....
  3. doi request reprint The global HIV epidemic: current status and challenges
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Curr HIV/AIDS Rep 10:111-2. 2013
    ..In the current fiscal climate careful thought needs to be given to how to efficiently optimise combinations of what is available to have the biggest impact in the context of limited human and infrastructure resources...
  4. doi request reprint Microbicides for the prevention of sexually transmitted HIV infection
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, University of KwaZulu Natal, South Africa
    Expert Rev Anti Infect Ther 11:13-23. 2013
    ....
  5. pmc Gender-sensitive reporting in medical research
    Shirin Heidari
    International AIDS Society, Geneva, Switzerland
    J Int AIDS Soc 15:11. 2012
    ..Journal editors are also promoters of ethical research and adequate standards of reporting, and requirements for inclusion of gender analyses should be integrated into editorial policies as a matter of urgency...
  6. pmc HIV prevalence among high school learners - opportunities for schools-based HIV testing programmes and sexual reproductive health services
    Ayesha B M Kharsany
    Centre for the AIDS Programme of Research in South Africa CAPRISA, 2nd Floor, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag 7, Congella, Durban 4013, South Africa
    BMC Public Health 12:231. 2012
    ..This study aimed at determining the HIV prevalence and explored the feasibility of HIV testing among high school learners...
  7. pmc Time for gender mainstreaming in editorial policies
    Shirin Heidari
    Journal of the International AIDS Society, 1216 Cointrin, Geneva, Switzerland
    J Int AIDS Soc 14:11. 2011
    ..Editors' associations could play an essential role in facilitating a transition to improved standard editorial policies...
  8. pmc Preventing HIV infection in women: a global health imperative
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Clin Infect Dis 50:S122-9. 2010
    ..Efforts to find a microbicide and HIV vaccine need to be matched with efforts to deepen understanding of acquisition of HIV in the female genital tract to inform development of targeted molecules for prevention of HIV infection...
  9. pmc Integration of antiretroviral therapy with tuberculosis treatment
    Salim S Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, Durban, South Africa
    N Engl J Med 365:1492-501. 2011
    ..We previously reported that integrating antiretroviral therapy (ART) with tuberculosis treatment reduces mortality. However, the timing for the initiation of ART during tuberculosis treatment remains unresolved...
  10. pmc Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Trials 12:67. 2011
    ..Microbicides could fill an important HIV prevention gap for sexually active women who are unable to successfully negotiate mutual monogamy or condom use...
  11. pmc Stabilizing HIV prevalence masks high HIV incidence rates amongst rural and urban women in KwaZulu-Natal, South Africa
    Quarraisha Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Int J Epidemiol 40:922-30. 2011
    ..In mature generalized human immunodeficiency virus (HIV) epidemics, as survival from accessing antiretroviral treatment (ART) increases, HIV prevalence data may be suboptimal and difficult to interpret without HIV incidence rates...
  12. pmc Co-enrollment in multiple HIV prevention trials - experiences from the CAPRISA 004 Tenofovir gel trial
    Quarraisha Abdool Karim
    Centre for the AIDS Program of Research in South Africa CAPRISA, Durban, South Africa
    Contemp Clin Trials 32:333-8. 2011
    ..We describe our experience, remedial action taken, inter-organizational collaboration and lessons learnt following the identification of co-enrolled participants...
  13. pmc High rates of tuberculosis in patients accessing HAART in rural South Africa
    Kogieleum Naidoo
    Centre for the AIDS Programme of Research in South Africa CAPRISA, University of KwaZulu Natal, Durban, South Africa Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY and Oxford Department of Public Health, University of Oxford, Oxford, United Kingdom
    J Acquir Immune Defic Syndr 65:438-46. 2014
    ..The challenge of early tuberculosis (TB) infection among rural patients accessing highly active antiretroviral therapy (HAART) in a resource-limited setting with high HIV and TB burden has not been fully quantified...
  14. pmc Uptake of provider-initiated HIV testing and counseling among women attending an urban sexually transmitted disease clinic in South Africa - missed opportunities for early diagnosis of HIV infection
    Ayesha B M Kharsany
    Centre for the AIDS Programme of Research in South Africa, University of KwaZulu Natal, Private Bag 7 Congella, Durban 4013, South Africa
    AIDS Care 22:533-7. 2010
    ....
  15. ncbi request reprint High prevalence of abnormal Pap smears among young women co-infected with HIV in rural South Africa - implications for cervical cancer screening policies in high HIV prevalence populations
    Asheber Gaym
    Faculty of Medicine, Addis Ababa University, Ethiopia, and Centre for the AIDS Programme of Research in South Africa CAPRISA, University of KwaZulu Natal, Durban, South Africa
    S Afr Med J 97:120-3. 2007
    ..To establish the relationship between HIV infection and cervical dysplasia in young women in rural South Africa...
  16. pmc HIV infection in high school students in rural South Africa: role of transmissions among students
    Ayesha B M Kharsany
    1 Centre for the AIDS Programme of Research in South Africa CAPRISA, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Congella, Durban, South Africa
    AIDS Res Hum Retroviruses 30:956-65. 2014
    ..The high burden of HIV infection among students was not associated with intraschool transmission in this rural setting. Lack of a living parent is an important factor defining high risk in this group of adolescents...
  17. ncbi request reprint HIV prevalence among high school learners - opportunities for school-based HIV testing programmes and sexual reproductive health services
    Ayesha B M Kharsany
    Centre for the AIDS Programme of Research in South Africa, Doris Duke Medical Research, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Confella, Durban, South Africa
    World Health Popul 13:43-50. 2012
    ..This study aimed at determining the HIV prevalence and explored the feasibility of HIV testing among high school learners...
  18. pmc Contraceptive choices, pregnancy rates, and outcomes in a microbicide trial
    Sengeziwe Sibeko
    Centre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Obstet Gynecol 118:895-904. 2011
    ....
  19. pmc High Burden of Human Papillomavirus (HPV) Infection among Young Women in KwaZulu-Natal, South Africa
    Sumayyah Ebrahim
    Department of Surgery, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    PLoS ONE 11:e0146603. 2016
    ..This study describes the prevalence of HPV genotypes and risk factors associated with HPV among young women ≤ 30 years of age in KwaZulu-Natal (KZN), South Africa...
  20. pmc Lower concentrations of chemotactic cytokines and soluble innate factors in the lower female genital tract associated with the use of injectable hormonal contraceptive
    Sinaye Ngcapu
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    J Reprod Immunol 110:14-21. 2015
    ..While the relationship between injectable HC use and STI or HIV risk is yet to be resolved, our data suggest that the effects of injectable HCs were similar in STI-positive and STI-negative participants. ..
  21. pmc Implementation of adolescent-friendly voluntary medical male circumcision using a school based recruitment program in rural KwaZulu-Natal, South Africa
    Carl Montague
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    PLoS ONE 9:e96468. 2014
    ..This study assessed the feasibility of recruiting male high school students for VMMC in such a setting in rural KwaZulu-Natal...
  22. pmc Measuring adherence by visual inspection of returned empty gel applicators in the CAPRISA 004 microbicide trial
    Tanuja N Gengiah
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Doris Duke Medical Research Institute 2nd Floor, University of KwaZulu Natal, 719 Umbilo Road, Durban, South Africa
    AIDS Behav 18:820-5. 2014
    ..Visual inspection enhanced both the accuracy of the adherence measurement and aided identification of mechanical problems with applicator use experienced by women in the trial...
  23. pmc HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response
    Salim S Abdool Karim
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Lancet 374:921-33. 2009
    ..Strong leadership, political will, social mobilisation, adequate human and financial resources, and sustainable development of health-care services are needed for successful implementation of these approaches...
  24. pmc Patients' readiness to start highly active antiretroviral treatment for HIV
    Hirut T Gebrekristos
    Centre for AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela, School of Medicine, Durban, South Africa
    BMJ 331:772-5. 2005
  25. ncbi request reprint Knowledge and acceptability of HAART among TB patients in Durban, South Africa
    Hirut T Gebrekristos
    Centre for AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, Durban, South Africa
    AIDS Care 17:767-72. 2005
    ..As access to HAART is expanded, information about HIV treatment options will need to be disseminated. TB centres may present unique opportunities for disseminating HIV prevention, care, and treatment options...
  26. pmc Timing of initiation of antiretroviral drugs during tuberculosis therapy
    Salim S Abdool Karim
    Centre for the AIDS Programme of Research in South Africa, University of KwaZulu Natal, Durban, South Africa
    N Engl J Med 362:697-706. 2010
    ..The optimal timing for the initiation of antiretroviral therapy in relation to tuberculosis therapy remains controversial...
  27. pmc Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    Quarraisha Abdool Karim
    Centre for the AIDS Program of Research in South Africa CAPRISA, Durban 4013, South Africa
    Science 329:1168-74. 2010
    ..Tenofovir gel could potentially fill an important HIV prevention gap, especially for women unable to successfully negotiate mutual monogamy or condom use...
  28. doi request reprint Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study
    Tulio de Oliveira
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Durban, South Africa University of KwaZulu Natal, Durban, South Africa Africa Centre for Population Health, Hlabisa, South Africa
    Lancet HIV 4:e41-e50. 2017
    ..We did a large-scale community-wide phylogenetic study to examine the underlying HIV transmission dynamics and the source and consequences of high rates of HIV infection in young women in South Africa...
  29. pmc No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial
    Denis R Chopera
    HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa KwaZulu Natal Research Institute for Tuberculosis and HIV, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Institute of Infectious Disease and Molecular Medicine, and the Division of Medical Virology, University of Cape Town and National Health Laboratory Services, Cape Town, South Africa Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada British Columbia Centre for Excellence in HIV AIDS, Vancouver, British Columbia, Canada
    PLoS ONE 8:e71758. 2013
    ..To investigate this, we assessed the in vitro function of gag-protease and nef sequences from participants who acquired HIV-1 during the CAPRISA 004 1% tenofovir microbicide gel trial...
  30. pmc Changes in Natural Killer cell activation and function during primary HIV-1 Infection
    Vivek Naranbhai
    CAPRISA Centre for the AIDS Programme of Research in South Africa, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    PLoS ONE 8:e53251. 2013
    ..However, HIV dysregulates NK-cell responses. We dissected this bi-directional relationship to understand how HIV impacts NK-cell responses during primary HIV-1 infection...
  31. doi request reprint Relationship between levels of inflammatory cytokines in the genital tract and CD4+ cell counts in women with acute HIV-1 infection
    Lisa M Bebell
    Centre for the AIDS Programme of Research in South Africa, University of KwaZulu Natal, Durban, South Africa
    J Infect Dis 198:710-4. 2008
    ....
  32. pmc Preliminary outcomes of a paediatric highly active antiretroviral therapy cohort from KwaZulu-Natal, South Africa
    Anand Reddi
    Sinikithemba HIV AIDS Clinic, McCord Hospital, Durban, South Africa
    BMC Pediatr 7:13. 2007
    ..Few studies address the use of paediatric highly active antiretroviral therapy (HAART) in Africa...
  33. pmc Initiating antiretrovirals during tuberculosis treatment: a drug safety review
    Tanuja N Gengiah
    University of KwaZulu Natal, Centre for the AIDS Programme of Research in South Africa, 719 Umbilo Rd, Durban, 4013, South Africa
    Expert Opin Drug Saf 10:559-74. 2011
    ..Altered therapeutic concentrations may influence the chances of treatment success or toxicity...
  34. ncbi request reprint Global epidemiology of HIV-AIDS
    Salim S Abdool Karim
    Centre for the AIDS Program of Research in South Africa CAPRISA, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag X7, Congella, 4013 Durban, South Africa
    Infect Dis Clin North Am 21:1-17, vii. 2007
    ..This article describes the modes of HIV transmission, geographic distribution of the evolving AIDS pandemic, and case studies of each of the three types of HIV epidemics, and presents global trends in AIDS and mortality...
  35. ncbi request reprint HIV treatment in South Africa: overcoming impediments to get started
    Quarraisha Abdool Karim
    CAPRISA, University of KwaZulu Natal, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban 4013, South Africa
    Lancet 363:1394. 2004
  36. pmc Broadly neutralizing antibody specificities detected in the genital tract of HIV-1 infected women
    Nonhlanhla N Mkhize
    aNational Institute for Communicable DiseasesbUniversity of the Witwatersrand, Johannesburg, South AfricacDuke Human Vaccine Institute and Departments of Surgery, Immunology and Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USAdCentre for the AIDS Programme of Research in South Africa CAPRISA, University of KwaZulu Natal, DurbaneUniversity of Cape Town, Cape TownfNational Health Laboratory Services, Johannesburg, South Africa
    AIDS 30:1005-14. 2016
    ..We investigated whether antibodies in the genital tract from these women share similar epitope specificities and functional profiles as those in blood...
  37. doi request reprint Factors Driving the HIV Epidemic in Southern Africa
    Lyle R McKinnon
    Centre for the AIDS Programme of Research in South Africa CAPRISA, University of KwaZulu Natal, Nelson R Mandela School of Medicine, 719 Umbilo Road, Private Bag X7, Congella, Durban, 4013, South Africa
    Curr HIV/AIDS Rep 13:158-69. 2016
    ..In particular, we focus on young women as a key population in need of HIV prevention and highlight factors that increase their risk on several levels. ..
  38. pmc Asking the right questions: developing evidence-based strategies for treating HIV in women and children
    Quarraisha Abdool Karim
    Department of Epidemiology, Columbia University, New York, USA
    BMC Public Health 11:388. 2011
    ..The guideline's new goals present an opportunity for advancing the women and children's agenda outlined in the Consensus Statement...
  39. ncbi request reprint Direct questioning of genital symptoms: increasing opportunities for identifying and treating sexually transmitted infections in primary health-care settings
    Ayesha B M Kharsany
    Centre for the AIDS Programme of Research in South Africa CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa
    Afr J Reprod Health 10:105-12. 2006
    ....
  40. ncbi request reprint A pilot study of once-daily antiretroviral therapy integrated with tuberculosis directly observed therapy in a resource-limited setting
    Christopher Jack
    Nelson R Mandela School of Medicine, University of Kwa Zulu Natal, Durban, South Africa
    J Acquir Immune Defic Syndr 36:929-34. 2004
    ..This pilot study demonstrates that TB/DOT programs can be feasible and effective sites for HIV identification and the introduction and monitoring of a once-daily HAART regimen in resource-limited settings...
  41. pmc Impact of an adherence intervention on the effectiveness of tenofovir gel in the CAPRISA 004 trial
    Leila Essop Mansoor
    Centre for the AIDS Programme of Research in South Africa, 2nd Floor, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag X7, Congella, 4013, South Africa
    AIDS Behav 18:841-8. 2014
    ..Following implementation of the ASP, microbicide adherence improved with a concomitant increase in the effectiveness of tenofovir gel...
  42. pmc Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study
    Francois van Loggerenberg
    Centre for the AIDS Programme of Research in South Africa CAPRISA, University of KwaZulu Natal, Durban, South Africa
    PLoS ONE 3:e1954. 2008
    ..To describe the baseline demographic data, clinical characteristics and HIV-incidence rates of a cohort at high risk for HIV infection in South Africa as well as the challenges experienced in establishing and maintaining the cohort...