Richard Kaplan

Summary

Affiliation: University of Cape Town
Country: South Africa

Publications

  1. pmc Identification of losses to follow-up in a community-based antiretroviral therapy clinic in South Africa using a computerized pharmacy tracking system
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    BMC Infect Dis 10:329. 2010
  2. pmc Loss to follow-up and mortality among pregnant women referred to a community clinic for antiretroviral treatment
    Richard Kaplan
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS 22:1679-81. 2008
  3. pmc Increasing transfers-out from an antiretroviral treatment service in South Africa: patient characteristics and rates of virological non-suppression
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e57907. 2013
  4. pmc Treatment outcomes in HIV-infected adolescents attending a community-based antiretroviral therapy clinic in South Africa
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925 Cape Town, South Africa
    BMC Infect Dis 12:21. 2012
  5. pmc Changes in programmatic outcomes during 7 years of scale-up at a community-based antiretroviral treatment service in South Africa
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 56:e1-8. 2011
  6. pmc Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    AIDS 23:335-42. 2009
  7. pmc Time to initiation of antiretroviral therapy among patients with HIV-associated tuberculosis in Cape Town, South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 57:136-40. 2011
  8. doi request reprint Low prevalence of renal dysfunction in HIV-infected pregnant women: implications for guidelines for the prevention of mother-to-child transmission of HIV
    Landon Myer
    School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Trop Med Int Health 18:1400-5. 2013
  9. pmc Delays in starting antiretroviral therapy in patients with HIV-associated tuberculosis accessing non-integrated clinical services in a South African township
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 11:258. 2011
  10. pmc Rates of switching antiretroviral drugs in a primary care service in South Africa before and after introduction of tenofovir
    Christine Njuguna
    Desmond Tutu HIV Centre, Institute for Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e63596. 2013

Collaborators

Detail Information

Publications24

  1. pmc Identification of losses to follow-up in a community-based antiretroviral therapy clinic in South Africa using a computerized pharmacy tracking system
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    BMC Infect Dis 10:329. 2010
    ..We determined the duration of pharmacy delay that optimally identified true LTFU...
  2. pmc Loss to follow-up and mortality among pregnant women referred to a community clinic for antiretroviral treatment
    Richard Kaplan
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS 22:1679-81. 2008
    ..This finding highlights the need for programmatic interventions to address retention in care for this patient population...
  3. pmc Increasing transfers-out from an antiretroviral treatment service in South Africa: patient characteristics and rates of virological non-suppression
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e57907. 2013
    ..To determine the proportion, characteristics and outcomes of patients who transfer-out from an antiretroviral therapy (ART) service in a South African township...
  4. pmc Treatment outcomes in HIV-infected adolescents attending a community-based antiretroviral therapy clinic in South Africa
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925 Cape Town, South Africa
    BMC Infect Dis 12:21. 2012
    ..The present study therefore compared the treatment outcomes in adolescents with those of young adults at a public sector community-based ART programme in Cape Town, South Africa...
  5. pmc Changes in programmatic outcomes during 7 years of scale-up at a community-based antiretroviral treatment service in South Africa
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 56:e1-8. 2011
    ..To assess sustainability of programmatic outcomes in a community-based antiretroviral therapy (ART) service in South Africa during 7 years of scale-up...
  6. pmc Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    AIDS 23:335-42. 2009
    ..To determine the relationship between mortality risk and the CD4 cell response to antiretroviral therapy (ART)...
  7. pmc Time to initiation of antiretroviral therapy among patients with HIV-associated tuberculosis in Cape Town, South Africa
    Stephen D Lawn
    The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 57:136-40. 2011
    ..7%, and 51.1% of patients started ART within 2, 4, and 8 weeks of tuberculosis treatment, respectively. Operational barriers must be tackled to permit further acceleration of ART initiation as recommended by 2010 WHO ART guidelines...
  8. doi request reprint Low prevalence of renal dysfunction in HIV-infected pregnant women: implications for guidelines for the prevention of mother-to-child transmission of HIV
    Landon Myer
    School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Trop Med Int Health 18:1400-5. 2013
    ....
  9. pmc Delays in starting antiretroviral therapy in patients with HIV-associated tuberculosis accessing non-integrated clinical services in a South African township
    Stephen D Lawn
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 11:258. 2011
    ..We examined the timing of ART among patients receiving care provided by non-integrated TB and ART services in Cape Town, South Africa...
  10. pmc Rates of switching antiretroviral drugs in a primary care service in South Africa before and after introduction of tenofovir
    Christine Njuguna
    Desmond Tutu HIV Centre, Institute for Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e63596. 2013
    ..This study describes the patterns and risk factors for drug changes of these antiretroviral drugs in adults...
  11. pmc Antiretroviral treatment uptake in patients with HIV-associated TB attending co-located TB and ART services
    Mweete Debra Nglazi
    University of Cape Town, South Africa
    S Afr Med J 102:936-9. 2012
    ..Delivery of integrated care for patients with HIV-associated TB is challenging. We assessed the uptake and timing of antiretroviral treatment (ART) among eligible patients attending a primary care service with co-located ART and TB clinics...
  12. pmc The impact of gender and income on survival and retention in a South African antiretroviral therapy programme
    Morna Cornell
    University of Cape Town, South Africa
    Trop Med Int Health 14:722-31. 2009
    ..We investigated the association of gender and income with survival and retention in a South African ART programme...
  13. pmc Nurse versus doctor management of HIV-infected patients receiving antiretroviral therapy (CIPRA-SA): a randomised non-inferiority trial
    Ian Sanne
    Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Lancet 376:33-40. 2010
    ..We compared outcomes of nurse versus doctor management of ART care for HIV-infected patients...
  14. ncbi request reprint Conservation of first-line antiretroviral treatment regimen where therapeutic options are limited
    Catherine Orrell
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
    Antivir Ther 12:83-8. 2007
    ....
  15. pmc Mother-to-child transmission of HIV in a community-based antiretroviral clinic in South Africa
    Felicity C Fitzgerald
    Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town
    S Afr Med J 100:827-31. 2010
    ..To examine the uptake of ART among pregnant women referred to an ART service and the associated rates and risk factors for vertical HIV transmission...
  16. doi request reprint Renal impairment in HIV-infected patients initiating tenofovir-containing antiretroviral therapy regimens in a Primary Healthcare Setting in South Africa
    Monika Kamkuemah
    Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Trop Med Int Health 20:518-26. 2015
    ..We aimed to assess the prevalence and incidence of renal impairment in a primary care setting in sub-Saharan Africa...
  17. pmc Impact of ART on TB case fatality stratified by CD4 count for HIV-positive TB patients in Cape Town, South Africa (2009-2011)
    Richard Kaplan
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Science, University of Cape Town, Cape Town, South Africa City Health Directorate, City of Cape Town, South Africa and Department of Medicine, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 66:487-94. 2014
    ..To identify determinants of tuberculosis (TB) case fatality including the impact of antiretroviral therapy (ART) at different CD4 thresholds for HIV-positive adult and adolescent TB patients...
  18. pmc Burden of new and recurrent tuberculosis in a major South African city stratified by age and HIV-status
    Robin Wood
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    PLoS ONE 6:e25098. 2011
    ....
  19. pmc The impact of HIV status and antiretroviral treatment on TB treatment outcomes of new tuberculosis patients attending co-located TB and ART services in South Africa: a retrospective cohort study
    Mweete D Nglazi
    The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and the Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 15:536. 2015
    ..We, therefore, assessed TB treatment outcomes in relation to HIV infection and antiretroviral therapy (ART) among TB patients attending a primary care service with co-located ART and TB clinics in Cape Town, South Africa...
  20. pmc Virological breakthrough: a risk factor for loss to followup in a large community-based cohort on antiretroviral therapy
    Catherine Orrell
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town 7925, South Africa
    AIDS Res Treat 2011:469127. 2011
    ..While 67% of those who experience initial virological breakthrough resuppress after an adherence intervention, these individuals are significantly less likely be retained in care than those who remain virologically suppressed throughout...
  21. ncbi request reprint Substitutions due to antiretroviral toxicity or contraindication in the first 3 years of antiretroviral therapy in a large South African cohort
    Andrew Boulle
    Infectious Disease Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Antivir Ther 12:753-60. 2007
    ..The patterns and reasons for antiretroviral therapy (ART) drug substitutions are poorly described in resource-limited settings...
  22. doi request reprint Outcomes of a nurse-managed service for stable HIV-positive patients in a large South African public sector antiretroviral therapy programme
    Anna Grimsrud
    Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    Trop Med Int Health 19:1029-39. 2014
    ..Models of care utilizing task shifting and decentralization are needed to support growing ART programmes. We compared patient outcomes between a doctor-managed clinic and a nurse-managed down-referral site in Cape Town, South Africa...
  23. ncbi request reprint Promoting retention in care: an effective model in an antiretroviral treatment service in South Africa
    Stephen D Lawn
    Clin Infect Dis 45:803. 2007
  24. ncbi request reprint Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma
    Jennifer A Quinn
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Oncol 20:2277-83. 2002
    ....