G J Hofmeyr

Summary

Affiliation: University of the Witwatersrand
Country: South Africa

Publications

  1. doi What (not) to do before delivery? Prevention of fetal meconium release and its consequences
    G J Hofmeyr
    Effective Care Research Unit, Eastern Cape Department of Health, University of the Witwatersrand, University of Fort Hare, South Africa
    Early Hum Dev 85:611-5. 2009
  2. ncbi Side-effects of oral misoprostol in the third stage of labour--a randomised placebo-controlled trial
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and Effective Care Research Unit, University of the Witwatersrand, Johannesburg
    S Afr Med J 91:432-5. 2001
  3. ncbi Uterine massage and postpartum blood loss
    H Abdel-Aleem
    Department of Obstetrics and Gynecology, Assiut University Hospital, Assiut, Egypt
    Int J Gynaecol Obstet 93:238-9. 2006
  4. doi Misoprostol for the prevention and treatment of postpartum haemorrhage
    G Justus Hofmeyr
    Effective Care Research Unit, University of the Witwatersrand University of Fort Hare East London Hospital Complex, South Africa
    Best Pract Res Clin Obstet Gynaecol 22:1025-41. 2008
  5. doi Obstetric care in low-resource settings: what, who, and how to overcome challenges to scale up?
    G Justus Hofmeyr
    Effective Care Research Unit, Eastern Cape Department of Health, Universities of the Witwatersrand and Fort Hare, South Africa
    Int J Gynaecol Obstet 107:S21-44, S44-5. 2009
  6. ncbi Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
    A N Atallah
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2000
  7. ncbi Hands and knees posture in late pregnancy or labour for fetal malposition (lateral or posterior)
    G J Hofmeyr
    University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, Frere and Cecilia Makiwane Hospitals, Private Bag X 9047, East London, Eastern Cape, South Africa, 5200
    Cochrane Database Syst Rev . 2005
  8. ncbi Planned Caesarean section for term breech delivery
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2001
  9. ncbi Vaginal misoprostol for cervical ripening and induction of labour
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2001
  10. ncbi Vaginal misoprostol for cervical ripening and induction of labour
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2003

Collaborators

Detail Information

Publications62

  1. doi What (not) to do before delivery? Prevention of fetal meconium release and its consequences
    G J Hofmeyr
    Effective Care Research Unit, Eastern Cape Department of Health, University of the Witwatersrand, University of Fort Hare, South Africa
    Early Hum Dev 85:611-5. 2009
    ..Meconium-stained amniotic fluid is a common occurrence which places the mother at risk of escalating obstetric interventions, and the baby at risk of meconium aspiration syndrome...
  2. ncbi Side-effects of oral misoprostol in the third stage of labour--a randomised placebo-controlled trial
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and Effective Care Research Unit, University of the Witwatersrand, Johannesburg
    S Afr Med J 91:432-5. 2001
    ..Large randomised trials are needed to assess the effectiveness of misoprostol in the prevention of postpartum haemorrhage, against which the disadvantages demonstrated here can be weighed...
  3. ncbi Uterine massage and postpartum blood loss
    H Abdel-Aleem
    Department of Obstetrics and Gynecology, Assiut University Hospital, Assiut, Egypt
    Int J Gynaecol Obstet 93:238-9. 2006
  4. doi Misoprostol for the prevention and treatment of postpartum haemorrhage
    G Justus Hofmeyr
    Effective Care Research Unit, University of the Witwatersrand University of Fort Hare East London Hospital Complex, South Africa
    Best Pract Res Clin Obstet Gynaecol 22:1025-41. 2008
    ..To date, there is very limited evidence for the effectiveness of misoprostol, the lowest effective dose and the magnitude of adverse effects, both direct and indirect. The need for further research is a matter of great urgency...
  5. doi Obstetric care in low-resource settings: what, who, and how to overcome challenges to scale up?
    G Justus Hofmeyr
    Effective Care Research Unit, Eastern Cape Department of Health, Universities of the Witwatersrand and Fort Hare, South Africa
    Int J Gynaecol Obstet 107:S21-44, S44-5. 2009
    ..Each year, approximately 2 million babies die because of complications of childbirth, primarily in settings where effective care at birth, particularly prompt cesarean delivery, is unavailable...
  6. ncbi Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
    A N Atallah
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2000
    ..Calcium supplementation may prevent high blood pressure through a number of mechanisms and may help to prevent preterm labour...
  7. ncbi Hands and knees posture in late pregnancy or labour for fetal malposition (lateral or posterior)
    G J Hofmeyr
    University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, Frere and Cecilia Makiwane Hospitals, Private Bag X 9047, East London, Eastern Cape, South Africa, 5200
    Cochrane Database Syst Rev . 2005
    ..It is possible that certain positions adopted by the mother may influence the baby's position...
  8. ncbi Planned Caesarean section for term breech delivery
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2001
    ..Routine use of caesarean section for breech presentation is widespread. However, poor outcomes after breech birth might be the result of underlying conditions causing breech presentation rather than damage during delivery...
  9. ncbi Vaginal misoprostol for cervical ripening and induction of labour
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2001
    ..This is one of a series of reviews of methods of cervical ripening and labour induction using standardised methodology...
  10. ncbi Vaginal misoprostol for cervical ripening and induction of labour
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2003
    ..This is one of a series of reviews of methods of cervical ripening and labour induction using standardised methodology...
  11. ncbi Vaginal misoprostol for cervical ripening and induction of labour
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2001
    ..This is one of a series of reviews of methods of cervical ripening and labour induction using standardised methodology...
  12. ncbi External cephalic version facilitation for breech presentation at term
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2001
    ..Tocolytic drugs to relax the uterus as well as other methods have been also used in an attempt to facilitate external cephalic version at term...
  13. ncbi Amnioinfusion for meconium-stained liquor in labour
    G J Hofmeyr
    Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2002
    ..However, it may be that the mechanism of effect is that it corrects oligohydramnios (reduced amniotic fluid), for which thick meconium staining is a marker...
  14. ncbi Maternal hydration for increasing amniotic fluid volume in oligohydramnios and normal amniotic fluid volume
    G J Hofmeyr
    Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2002
    ..Simple maternal hydration has been suggested as a way of increasing amniotic fluid volume in order to reduce some of these problems...
  15. ncbi Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
    A N Atallah
    Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2002
    ..Calcium supplementation may prevent high blood pressure through a number of mechanisms and may help to prevent preterm labour...
  16. ncbi Piracetam for fetal distress in labour
    G J Hofmeyr
    Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2002
    ..Piracetam is thought to promote the metabolism of brain cells when they are hypoxic. It has been used to prevent adverse effects of fetal distress...
  17. ncbi Prophylactic intravenous preloading for regional analgesia in labour
    G J Hofmeyr
    Director, Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2002
    ..Intravenous fluid preloading (volume expansion) may help to reduce maternal hypotension. Newer protocols using weaker solutions of local anaesthetic, and opioid only blocks, may reduce the need for preloading...
  18. ncbi Cephalic version by postural management for breech presentation
    G J Hofmeyr
    Effective Care Research Unit, University of the Witwatersrand, Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2000
    ..It is possible that maternal posture may influence fetal position. Many postural techniques have been used to promote cephalic version...
  19. ncbi Interventions to help external cephalic version for breech presentation at term
    G J Hofmeyr
    Frere Cecilia Makiwane Hospitals, Private Bag 9047, East London 5200, Eastern Cape, South Africa
    Cochrane Database Syst Rev . 2002
    ..Tocolytic drugs to relax the uterus as well as other methods have been also used in an attempt to facilitate external cephalic version at term...
  20. doi Uterine massage for preventing postpartum haemorrhage
    G Justus Hofmeyr
    Department of Obstetrics and Gynaecology, East London Hospital Complex, University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, East London, South Africa
    Cochrane Database Syst Rev . 2008
    ..In addition to the standard known strategies to prevent and treat PPH, there is a need for simple, non-expensive techniques which can be applied in low-resourced settings to prevent or treat PPH...
  21. doi WITHDRAWN: Amnioinfusion for meconium-stained liquor in labour
    G Justus Hofmeyr
    Department of Obstetrics and Gynaecology, East London Hospital Complex, University of the Witwatersrand, University of Fort Hare, East London, Eastern Cape, South Africa, 5200
    Cochrane Database Syst Rev . 2009
    ..However, it may be that the mechanism of effect is that it corrects oligohydramnios (reduced amniotic fluid), for which thick meconium staining is a marker...
  22. doi Techniques for caesarean section
    G J Hofmeyr
    University of the Witwatersrand, Department of Obstetrics and Gynaecology, East London Hospital Complex, Frere and Cecilia Makiwane Hospitals, Private Bag X 9047, East London, Eastern Cape, South Africa, 5200
    Cochrane Database Syst Rev . 2008
    ..Rates of caesarean section (CS) have been rising globally. It is important to use the most effective and safe technique...
  23. pmc Misoprostol for treating postpartum haemorrhage: a randomized controlled trial [ISRCTN72263357]
    G Justus Hofmeyr
    Effective Care Research Unit, University of Witwatersrand and Fort Hare, and East London Hospital Complex, East London, South Africa
    BMC Pregnancy Childbirth 4:16. 2004
    ..Larger studies are needed to assess substantive outcomes and risks before misoprostol enters routine use...
  24. pmc Making stillbirths count, making numbers talk - issues in data collection for stillbirths
    J Frederik Frøen
    Department of Genes and Environment, Division of Epidemiology, Norwegian Institute of Public Health, P O Box 4404 Nydalen, N 0403 Oslo, Norway
    BMC Pregnancy Childbirth 9:58. 2009
    ..This information will guide efforts to prevent stillbirths and improve quality of care...
  25. pmc Promoting childbirth companions in South Africa: a randomised pilot study
    Heather Brown
    Worthing Hospital, Lyndhurst Road, Worthing, W Sussex, UK
    BMC Med 5:7. 2007
    ..We piloted a multi-faceted intervention to encourage uptake of childbirth companions in state hospitals, and hypothesised that lay carers would improve the behaviour of health professionals...
  26. pmc Misoprostol to prevent and treat postpartum haemorrhage: a systematic review and meta-analysis of maternal deaths and dose-related effects
    G Justus Hofmeyr
    East London Hospital Complex and University of the Witwatersrand, East London, South Africa
    Bull World Health Organ 87:666-77. 2009
    ..To review maternal deaths and the dose-related effects of misoprostol on blood loss and pyrexia in randomized trials of misoprostol use for the prevention or treatment of postpartum haemorrhage...
  27. pmc Proteinuria as a predictor of complications of pre-eclampsia
    G Justus Hofmeyr
    Effective Care Research Unit, Eastern Cape Department of Health, Universities of the Witwatersrand and Fort Hare, South Africa
    BMC Med 7:11. 2009
    ..The systematic review of 16 primary papers including over 6700 patients by Thangaratinam and colleagues published this month in BMC Medicine suggests otherwise. This finding may influence our management of pre-eclampsia...
  28. ncbi Evidence-based intrapartum care
    G J Hofmeyr
    Effective Care Research Unit, East London Hospital Complex, University of the Witwatersrand University of Fort Hare Eastern Cape Department of Health, P Bag X9047, East London 5201, South Africa
    Best Pract Res Clin Obstet Gynaecol 19:103-15. 2005
    ....
  29. doi Calcium supplementation during pregnancy for preventing hypertensive disorders is not associated with changes in platelet count, urate, and urinary protein: a randomized control trial
    G J Hofmeyr
    Effective Care Research Unit, East London Hospital Complex University of the Witwatersrand University of Fort Hare, East London, South Africa
    Hypertens Pregnancy 27:299-304. 2008
    ..To test the hypothesis that calcium supplementation inhibits the underlying pathological processes in women with preeclampsia...
  30. ncbi Induction of labour with an unfavourable cervix
    G Justus Hofmeyr
    East London Hospital Complex, South Africa Effective Care Research Unit, Frere Maternity Hospital, University of the Witwatersrand, East London
    Best Pract Res Clin Obstet Gynaecol 17:777-94. 2003
    ..Very large trials are needed to evaluate rare adverse outcomes.Extra-amniotic saline infusion is an effective method which appears to reduce the risk of uterine hyperstimulation that occurs with the use of exogenous uterotonics...
  31. ncbi Obstructed labor: using better technologies to reduce mortality
    G J Hofmeyr
    East London Hospital Complex, Effective Care Research Unit, University of Witwatersrand, South Africa
    Int J Gynaecol Obstet 85:S62-72. 2004
    ..To identify, from the best available evidence, underutilized and promising technologies that may reduce maternal mortality from obstructed labor...
  32. ncbi Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
    G J Hofmeyr
    University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, Frere and Cecilia Makiwane Hospitals, Private Bag X 9047, East London, Eastern Cape, South Africa 5200
    Cochrane Database Syst Rev . 2006
    ..Pre-eclampsia and eclampsia are common causes of serious morbidity and death. Calcium supplementation may reduce the risk of pre-eclampsia through a number of mechanisms, and may help to prevent preterm labour...
  33. ncbi Dietary calcium supplementation for prevention of pre-eclampsia and related problems: a systematic review and commentary
    G J Hofmeyr
    Effective Care Research Unit, East London Hospital Complex, University of the Witwatersrand University of Fort Hare, East London, South Africa
    BJOG 114:933-43. 2007
    ..Calcium supplementation during pregnancy may reduce the risk of hypertensive disorders of pregnancy...
  34. ncbi Titrated oral misoprostol solution for induction of labour: a multi-centre, randomised trial
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Frere/Cecilia Makiwane Hospitals and Effective Care Research Unit, University of Witwatersrand, South Africa
    BJOG 108:952-9. 2001
    ..Misoprostol is not registered for use in pregnant women, and further research is needed to confirm optimal and safe dosages...
  35. ncbi Calcium supplementation to prevent pre-eclampsia--a systematic review
    G J Hofmeyr
    Effective Care Research Unit, East London Hospital Complex, University of the Witwatersrand, Johannesburg Fort Hare University, East London, E Cape
    S Afr Med J 93:224-8. 2003
    ..Calcium supplementation during pregnancy may prevent high blood pressure and preterm labour...
  36. ncbi Amnioinfusion
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, Johannesburg, South Africa
    Eur J Obstet Gynecol Reprod Biol 64:159-65. 1996
    ..Larger trials are needed to determine whether amnioinfusion is associated with an effect on perinatal mortality, and whether complications such as umbilical cord prolapse are increased...
  37. ncbi Titrated oral misoprostol solution--a new method of labour induction
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital, Effective Care Research Unit, University of the Witwatersrand, Johannesburg
    S Afr Med J 91:775-6. 2001
    ..A multicentre randomised trial of this method is underway. We emphasise the dangers inherent in the current unregistered use of misoprostol in clinical practice...
  38. ncbi Induction of labour with misoprostol
    G J Hofmeyr
    East London Hospital Complex, East London 5200, South Africa
    Curr Opin Obstet Gynecol 13:577-81. 2001
    ..Using small dosages appears to reduce adverse outcomes. Very large trials are needed to evaluate rare adverse outcomes...
  39. ncbi Hypovolaemic shock
    G J Hofmeyr
    Effective Care Research Unit, Cecilia Makiwane and Frere Hospitals, University of the Witwatersrand, East London 5200, Eastern Cape, South Africa
    Best Pract Res Clin Obstet Gynaecol 15:645-62. 2001
    ..Bedside diagnostic ultrasound has several applications in the evaluation of obstetric hypovolaemic shock...
  40. ncbi Labor induction and meconium: in vitro effects of oxytocin, dinoprostone and misoprostol on rat ileum relative to myometrium
    Baron B Matonhodze
    Effective Care Research Unit, University of the Witwatersrand, Parktown, Johannesburg, South Africa
    J Perinat Med 30:405-10. 2002
    ..These adverse effects may be caused by stimulation of bowel smooth muscle in the mother and in the fetus...
  41. ncbi Misoprostol to treat postpartum haemorrhage: a systematic review
    G Justus Hofmeyr
    Effective Care Research Unit, University of the Witwatersrand University of Fort Hare, East London Hospital Complex, South Africa
    BJOG 112:547-53. 2005
  42. ncbi Abdominal decompression in normal pregnancy
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Abdominal decompression was developed as a means of pain relief during labour. It has also been used for complications of pregnancy, and in healthy pregnant women in an attempt to improve fetal wellbeing and intellectual development...
  43. ncbi Planned caesarean section for term breech delivery
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Routine use of caesarean section for breech presentation is widespread. However poor outcomes after breech birth may be the result of underlying conditions causing breech presentation rather than damage during delivery...
  44. ncbi Maternal hydration for increasing amniotic fluid volume in oligohydramnios and normal amniotic fluid volume
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Simple maternal hydration has been suggested as a way of increasing amniotic fluid volume in order to reduce some of these problems...
  45. ncbi External cephalic version for breech presentation at term
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..External cephalic version may reduce the number of breech presentations and caesarean sections, but there also have been reports of increased perinatal mortality with the procedure...
  46. ncbi Expedited versus conservative approaches for vaginal delivery in breech presentation
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..In a vaginal breech birth there may be benefit from rapid delivery of the baby to prevent progressive acidosis. However, this needs to be weighed against the potential trauma of a quick delivery...
  47. ncbi Cephalic version by postural management for breech presentation
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..It is possible that maternal posture may influence fetal position. Many postural techniques have been used to promote cephalic version...
  48. ncbi Early compared with delayed oral fluids and food after caesarean section
    L Mangesi
    Effective Care Research Group, Frere Maternity Hospital, Private Bag X9047, East London, South Africa, 5200
    Cochrane Database Syst Rev . 2002
    ..It is customary for fluids and/or food to be withheld for a period of time after abdominal operations. After caesarean section, practices vary considerably. These discrepancies raise concern as to the bases of different practices...
  49. ncbi Tocolysis for preventing fetal distress in second stage of labour
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Uterine relaxation may improve placental blood flow and therefore fetal oxygenation. However there may also be adverse maternal cardiovascular effects...
  50. ncbi Hands/knees posture in late pregnancy or labour for fetal malposition (lateral or posterior)
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Lateral and posterior position of the fetal presenting parts may be associated with more painful, prolonged or obstructed labour and difficult delivery. It is possible that maternal posture may influence fetal position...
  51. ncbi Amnioinfusion for meconium-stained liquor
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, Parktown, Johannesburg, South Africa
    Curr Opin Obstet Gynecol 12:129-32. 2000
    ..The addition of antibiotics to the infusate has not been shown to reduce the risk of sepsis related to meconium...
  52. ncbi Hands and knees posture in late pregnancy or labour for fetal malposition (lateral or posterior)
    S Hunter
    Eastern Cape Department of Health University of the Witwatersrand Fort Hare, Effective Care Research Unit, East London, South Africa
    Cochrane Database Syst Rev . 2007
    ..It is possible that certain positions adopted by the mother may influence the baby's position...
  53. ncbi Piracetam for fetal distress in labour
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Piracetam is thought to promote the metabolism of brain cells when they are hypoxic. It has been used to prevent adverse effects of fetal distress...
  54. ncbi Operative versus conservative management for 'fetal distress' in labour
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Even with a correct diagnosis it is not clear whether an operative or conservative approach is better...
  55. ncbi Fetal movement counting for assessment of fetal wellbeing
    L Mangesi
    Frere Maternity Hospital, Effective Care Research Group, Private Bag X9047, East London, South Africa, 5200
    Cochrane Database Syst Rev . 2007
    ..Some clinicians believe that fetal movement counting is a good method as it allows the clinician to make appropriate interventions in good time. On the other hand, fetal movement counting may cause anxiety to women...
  56. ncbi Vaginal misoprostol for cervical ripening and labour induction in late pregnancy
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    Cochrane Database Syst Rev . 2000
    ..Although not yet registered for such use, misoprostol has been widely used for obstetric and gynaecological indications, such as induction of abortion and of labour...
  57. doi The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: An exploratory, randomized placebo controlled study
    G J Hofmeyr
    Department of Obstetrics and Gynaecology, East London Hospital Complex, University of the Witwatersrand, South Africa University of Fort Hare, Eastern Cape Department of Health, East London, South Africa Electronic address
    Pregnancy Hypertens 5:273-9. 2015
    ..Epidemiological findings suggest that the link between poverty and pre-eclampsia might be dietary calcium deficiency. Calcium supplementation has been associated with a modest reduction in pre-eclampsia, and also in blood pressure (BP)...
  58. ncbi WHO systematic review of maternal mortality and morbidity: the prevalence of uterine rupture
    G Justus Hofmeyr
    Effective Care Research Unit, Eastern Cape Department of Health University of Witwatersrand University of Fort Hare, South Africa
    BJOG 112:1221-8. 2005
    ..To determine the prevalence of uterine rupture worldwide...
  59. doi Chlorhexidine maternal-vaginal and neonate body wipes in sepsis and vertical transmission of pathogenic bacteria in South Africa: a randomised, controlled trial
    Clare L Cutland
    Department of Science and Technology National Research Foundation, Vaccine Preventable Diseases and Medical Research Council, Respiratory and Meningeal Pathogens Research Unit, University of Witwatersrand, Soweto, South Africa
    Lancet 374:1909-16. 2009
    ..We therefore assessed the efficacy of chlorhexidine in early-onset neonatal sepsis and vertical transmission of group B streptococcus...
  60. ncbi Misoprostol for induction of labor with a live fetus
    A Weeks
    School of Reproductive and Developmental Medicine, University of Liverpool, Liverpool Women s Hospital, Liverpool, UK
    Int J Gynaecol Obstet 99:S194-7. 2007
    ..Reports of uterine rupture in women with previous cesarean sections mean that it remains contraindicated in this group...
  61. ncbi Caesarean section for non-medical reasons at term
    T Lavender
    University of Central Lancashire, Department of Midwifery Studies, Preston, UK PR1 2HE
    Cochrane Database Syst Rev . 2006
    ..An unbiased assessment of advantages and disadvantages would assist discussion of what has become a contentious issue in modern obstetrics...
  62. ncbi Management of breech presentation in areas with high prevalence of HIV infection
    W R Holmes
    Centre for International Health, Macfarlane Burnet Institute for Medical Research and Public Health, GPO Box 2284, Melbourne 3001, Australia
    Int J Gynaecol Obstet 87:272-6. 2004
    ..To provide recommendations for the management of breech presentation in areas of high prevalence of human immunodeficiency virus (HIV) infection...