Andre Pascal Kengne

Summary

Affiliation: Medical Research Council
Country: South Africa

Publications

  1. doi request reprint Alternative indices of glucose homeostasis as biochemical diagnostic tests for abnormal glucose tolerance in an African setting
    Andre Pascal Kengne
    Non communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa Department of Medicine, University of Cape Town, Cape Town, South Africa Electronic address
    Prim Care Diabetes . 2017
  2. pmc Proliferator-activated receptor gamma Pro12Ala interacts with the insulin receptor substrate 1 Gly972Arg and increase the risk of insulin resistance and diabetes in the mixed ancestry population from South Africa
    Zelda Vergotine
    Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, PO Box 1906, Bellville 7530, Cape Town, South Africa
    BMC Genet 15:10. 2014
  3. pmc Fasting insulin sensitivity indices are not better than routine clinical variables at predicting insulin sensitivity among Black Africans: a clamp study in sub-Saharan Africans
    Eugene Sobngwi
    Department of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
    BMC Endocr Disord 14:65. 2014
  4. pmc Epidemiology of neurodegenerative diseases in sub-Saharan Africa: a systematic review
    Alain Lekoubou
    Department of Medicine, University of Cape Town, Cape Town, South Africa
    BMC Public Health 14:653. 2014
  5. pmc Polymorphisms in the non-muscle myosin heavy chain gene (MYH9) are associated with lower glomerular filtration rate in mixed ancestry diabetic subjects from South Africa
    Tandi Edith Matsha
    Department of Biomedical Sciences, Faculty of Health and Wellness Science, Cape Peninsula University of Technology, Cape Town, South Africa
    PLoS ONE 7:e52529. 2012
  6. pmc Risk models to predict hypertension: a systematic review
    Justin B Echouffo-Tcheugui
    Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
    PLoS ONE 8:e67370. 2013
  7. doi request reprint Cardiovascular diseases and diabetes as economic and developmental challenges in Africa
    Andre Pascal Kengne
    South African Medical Research Council and University of Cape Town, Cape Town, South Africa The George Institute for Global Health, Sydney, Australia Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Electronic address
    Prog Cardiovasc Dis 56:302-13. 2013
  8. pmc Chronic kidney diseases in mixed ancestry south African populations: prevalence, determinants and concordance between kidney function estimators
    Tandi E Matsha
    Department of Biomedical Sciences, Faculty of Health and Wellness Science, Cape Peninsula University of Technology, Cape Town, South Africa
    BMC Nephrol 14:75. 2013
  9. doi request reprint New insights on diabetes mellitus and obesity in Africa-Part 2: prevention, screening and economic burden
    Andre Pascal Kengne
    Department of Medicine, University of Cape Town and South African Medical Research Council, Cape Town, South Africa
    Heart 99:1072-7. 2013
  10. doi request reprint New insights on diabetes mellitus and obesity in Africa-part 1: prevalence, pathogenesis and comorbidities
    Andre Pascal Kengne
    Department of Medicine, University of Cape Town, Cape Town, South Africa
    Heart 99:979-83. 2013

Collaborators

Detail Information

Publications25

  1. doi request reprint Alternative indices of glucose homeostasis as biochemical diagnostic tests for abnormal glucose tolerance in an African setting
    Andre Pascal Kengne
    Non communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa Department of Medicine, University of Cape Town, Cape Town, South Africa Electronic address
    Prim Care Diabetes . 2017
    ..We assessed the ability of fasting plasma glucose (FPG), HbA1c and fructosamine, to diagnose OGTT-based abnormal glucose tolerance in mixed-ancestry South Africans...
  2. pmc Proliferator-activated receptor gamma Pro12Ala interacts with the insulin receptor substrate 1 Gly972Arg and increase the risk of insulin resistance and diabetes in the mixed ancestry population from South Africa
    Zelda Vergotine
    Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, PO Box 1906, Bellville 7530, Cape Town, South Africa
    BMC Genet 15:10. 2014
    ..Glucose tolerance status and insulin resistance/sensitivity were assessed...
  3. pmc Fasting insulin sensitivity indices are not better than routine clinical variables at predicting insulin sensitivity among Black Africans: a clamp study in sub-Saharan Africans
    Eugene Sobngwi
    Department of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
    BMC Endocr Disord 14:65. 2014
    ..We aimed to evaluate the predictive utility of common fasting insulin sensitivity indices, and non-laboratory surrogates [BMI, waist circumference (WC) and waist-to-height ratio (WHtR)] in sub-Saharan Africans without diabetes...
  4. pmc Epidemiology of neurodegenerative diseases in sub-Saharan Africa: a systematic review
    Alain Lekoubou
    Department of Medicine, University of Cape Town, Cape Town, South Africa
    BMC Public Health 14:653. 2014
    ..We conducted a systematic review of published studies on common neurodegenerative diseases, and HIV-related neurocognitive impairment in SSA, in order to identify research gaps and inform prevention and control solutions...
  5. pmc Polymorphisms in the non-muscle myosin heavy chain gene (MYH9) are associated with lower glomerular filtration rate in mixed ancestry diabetic subjects from South Africa
    Tandi Edith Matsha
    Department of Biomedical Sciences, Faculty of Health and Wellness Science, Cape Peninsula University of Technology, Cape Town, South Africa
    PLoS ONE 7:e52529. 2012
    ..We investigated the association of MYH9 SNPs with renal traits in a mixed-ancestry South African population prone to diabetes...
  6. pmc Risk models to predict hypertension: a systematic review
    Justin B Echouffo-Tcheugui
    Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
    PLoS ONE 8:e67370. 2013
    ..Risk prediction models may be of value in identifying those individuals at risk of developing hypertension who are likely to benefit most from interventions...
  7. doi request reprint Cardiovascular diseases and diabetes as economic and developmental challenges in Africa
    Andre Pascal Kengne
    South African Medical Research Council and University of Cape Town, Cape Town, South Africa The George Institute for Global Health, Sydney, Australia Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Electronic address
    Prog Cardiovasc Dis 56:302-13. 2013
    ..Structural, logistic, human capacity and organizational challenges to be surmounted during the implementations of these strategies will be reviewed. ..
  8. pmc Chronic kidney diseases in mixed ancestry south African populations: prevalence, determinants and concordance between kidney function estimators
    Tandi E Matsha
    Department of Biomedical Sciences, Faculty of Health and Wellness Science, Cape Peninsula University of Technology, Cape Town, South Africa
    BMC Nephrol 14:75. 2013
    ..We assessed the prevalence and determinants of CKD, and evaluated the concordance of commonly advocated estimators of glomerular filtration rate (eGFR) in a mixed ancestry population from South Africa...
  9. doi request reprint New insights on diabetes mellitus and obesity in Africa-Part 2: prevention, screening and economic burden
    Andre Pascal Kengne
    Department of Medicine, University of Cape Town and South African Medical Research Council, Cape Town, South Africa
    Heart 99:1072-7. 2013
    ..Moreover, translation strategies to prevent and control diabetes and obesity, on the continent, are still to be evaluated. ..
  10. doi request reprint New insights on diabetes mellitus and obesity in Africa-part 1: prevalence, pathogenesis and comorbidities
    Andre Pascal Kengne
    Department of Medicine, University of Cape Town, Cape Town, South Africa
    Heart 99:979-83. 2013
    ..The health consequences of diabetes are manifold, and include a complex interaction with other conditions like HIV infection and sickle cell disease/trait. ..
  11. doi request reprint Fibrinogen and future cardiovascular disease in people with diabetes: aetiological associations and risk prediction using individual participant data from nine community-based prospective cohort studies
    Andre P Kengne
    NCRP for Cardiovascular and Metabolic Disease, South African Medical Research Council and University of Cape Town, South Africa
    Diab Vasc Dis Res 10:143-51. 2013
    ..We assessed the associations of fibrinogen levels with cardiovascular disease (CVD) risks in people with and without diabetes, and quantified the value of adding fibrinogen to the established predictive algorithms for CVD...
  12. pmc Anaemia, haemoglobin level and cause-specific mortality in people with and without diabetes
    Andre Pascal Kengne
    National Collaborative Research Programme on Cardiovascular and Metabolic Disease, South African Medical Research Council and University of Cape Town, Cape Town, South Africa
    PLoS ONE 7:e41875. 2012
    ..We draw comparison of these effects with those apparent in diabetes-free individuals...
  13. doi request reprint Gamma-glutamyltransferase and risk of cardiovascular disease mortality in people with and without diabetes: pooling of three British Health Surveys
    Andre Pascal Kengne
    South African Medical Research Council and University of Cape Town, South Africa
    J Hepatol 57:1083-9. 2012
    ..We examined (a) the association of GGT with cardiovascular disease (CVD) and all-cause mortality in people with and without diabetes; and (b) the predictive validity observed when adding GGT to a CVD risk algorithm...
  14. pmc Association of C-reactive protein with cardiovascular disease mortality according to diabetes status: pooled analyses of 25,979 participants from four U.K. prospective cohort studies
    Andre Pascal Kengne
    NCRP for Cardiovascular and Metabolic Diseases, South African Medical Research Council and University of Cape Town, Cape Town, South Africa
    Diabetes Care 35:396-403. 2012
    ..This study investigated these issues and assessed the added value of CRP to predictions...
  15. doi request reprint Risk predictive modelling for diabetes and cardiovascular disease
    Andre Pascal Kengne
    Non Communicable Disease Research Unit, South African Medical Research Council and University of Cape Town, Cape Town, South Africa
    Crit Rev Clin Lab Sci 51:1-12. 2014
    ..A shift of focus from developing new CVD or diabetes prediction models to validating the existing ones will improve their adoption in routine practice...
  16. pmc The Distribution of Obesity Phenotypes in HIV-Infected African Population
    Kim Anh Nguyen
    Non communicable Diseases Research Unit, South African Medical Research Council, Cape Town 7505, South Africa
    Nutrients 8:. 2016
    ..This highlights the importance of general measures targeting an overall improvement in cardiometabolic risk profile across the spectrum of BMI distribution in all adults with HIV. ..
  17. pmc Optimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girls
    Tandi E Matsha
    Department of Biomedical Technology, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Cape Town, South Africa
    PLoS ONE 8:e71133. 2013
    ..The purpose of this study was to determine the optimal WHtR for children from South Africa, and investigate variations by gender, ethnicity and residence in the achieved value...
  18. pmc The ADVANCE cardiovascular risk model and current strategies for cardiovascular disease risk evaluation in people with diabetes
    Andre Pascal Kengne
    South African Medical Research Council, Tygerberg, Cape Town, South Africa
    Cardiovasc J Afr 24:376-81. 2013
    ....
  19. pmc An assessment of discriminatory power of office blood pressure measurements in predicting optimal ambulatory blood pressure control in people with type 2 diabetes
    Andre Pascal Kengne
    South African Medical Research Council and University of Cape Town, Cape Town, South Africa
    Pan Afr Med J 19:231. 2014
    ..We assessed the performance of office BP in predicting optimal ambulatory BP control in sub-Saharan Africans with type 2 diabetes (T2DM)...
  20. doi request reprint Diabetes in the Africa Region: an update
    Nasheeta Peer
    Chronic Diseases of Lifestyle Research Unit, South African Medical Research Council, Durban, South Africa
    Diabetes Res Clin Pract 103:197-205. 2014
    ..1%) compared to lower- and upper-middle income AFR countries (46.0%). This highlights the inadequate response of local health systems which need to provide accessible, affordable and optimal care for diabetes. ..
  21. ncbi request reprint Burden, Determinants, and Pharmacological Management of Hypertension in HIV-Positive Patients and Populations: A Systematic Narrative Review
    Kim Anh Nguyen
    Non communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa
    AIDS Rev 17:83-95. 2015
    ..Further research examining the development of hypertension and its associated care in HIV-positive patients is required to optimize management of the dual conditions. ..
  22. pmc Coincidence of diabetes mellitus and hypertension in a semi-urban Cameroonian population: a cross-sectional study
    Jean Claude Katte
    Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMC Public Health 14:696. 2014
    ..We determined the rate of coincident diabetes and hypertension and assessed the levels of co-awareness, treatment and control in a semi-urban population in Cameroon...
  23. pmc Predictors of hospitalisations for heart failure and mortality in patients with pulmonary hypertension associated with left heart disease: a systematic review
    Anastase Dzudie
    Douala General Hospital and Buea Faculty of Health Sciences, Douala, Cameroon Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    BMJ Open 4:e004843. 2014
    ..We conducted a systematic review to investigate the predictors of hospitalisations for heart failure and mortality in patients with PH-LHD...