L Solnica Krezel

Summary

Publications

  1. ncbi request reprint The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures
    K Fekany
    Department of Molecular Biology, Vanderbilt University, Box 1820, Station B, Nashville, TN 37235, USA
    Development 126:1427-38. 1999
  2. ncbi request reprint Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors
    J M Topczewska
    Department of Cell Biology and Howard Hughes Medical Institute, Vanderbilt Medical Center, Nashville, TN 37232 2175, USA
    Mech Dev 100:343-7. 2001
  3. pmc Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino
    E M Gonzalez
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Genes Dev 14:3087-92. 2000
  4. ncbi request reprint Zebrafish nodal-related 2 encodes an early mesendodermal inducer signaling from the extraembryonic yolk syncytial layer
    C E Erter
    Department of Molecular Biology, Vanderbilt University, 1161 21st Avenue South, Nashville, Tennessee, 37232 2175, USA
    Dev Biol 204:361-72. 1998
  5. ncbi request reprint Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish
    F Marlow
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    Dev Biol 203:382-99. 1998
  6. ncbi request reprint The role of the homeodomain protein Bozozok in zebrafish axis formation
    L Solnica-Krezel
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    Int J Dev Biol 45:299-310. 2001
  7. ncbi request reprint Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension
    D S Sepich
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235 1634, USA
    Genesis 27:159-73. 2000
  8. ncbi request reprint The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension
    J Topczewski
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Dev Cell 1:251-64. 2001
  9. pmc The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish
    J M Topczewska
    Department of Cell Biology and Howard Hughes Medical Institute, Vanderbilt Medical Center, Nashville, Tennessee 37232 2175, USA
    Genes Dev 15:2483-93. 2001
  10. ncbi request reprint Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
    I A Drummond
    Renal Unit, Massachusetts General Hospital, Charlestown MA 02129, USA
    Development 125:4655-67. 1998

Collaborators

  • C V Wright
  • Lilianna Solnica-Krezel
  • A F Schier
  • M Hammerschmidt
  • Jarema J Malicki
  • I A Drummond
  • D S Sepich
  • Igor B Dawid
  • W Driever
  • Didier Y Stainier
  • J Topczewski
  • J M Topczewska
  • C E Erter
  • D L Stemple
  • E M Gonzalez
  • S C Neuhauss
  • F Zwartkruis
  • S Abdelilah
  • B L Hogan
  • H M Pogoda
  • H Hashimoto
  • A Kawahara
  • C A Henry
  • M Hibi
  • A Carmany-Rampey
  • T Hirano
  • Y Yamanaka
  • K Fekany
  • V Miller-Bertoglio
  • F Marlow
  • E Mountcastle-Shah
  • B M Weinstein
  • M Pack
  • M C Fishman
  • Z Rangini
  • D C Myers
  • A Shostak
  • T Kume
  • Z Lele
  • C Walker
  • A Amores
  • N Basler
  • T P Wilm
  • J Postlethwait
  • M Itoh
  • T Shimizu
  • K Fekany-Lee
  • D Meyer
  • M Burr Hille
  • L A Hall
  • T Wilm
  • M S Cooper
  • S Yamashita
  • C Erter
  • D Stemple
  • M A Gates
  • A Renucci
  • A Radbill
  • M E Halpern
  • T Leung
  • M Fürthauer
  • B Thisse
  • H I Sirotkin
  • W S Talbot
  • C Thisse
  • L Abbas
  • M Weaver
  • M Harvey

Detail Information

Publications25

  1. ncbi request reprint The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures
    K Fekany
    Department of Molecular Biology, Vanderbilt University, Box 1820, Station B, Nashville, TN 37235, USA
    Development 126:1427-38. 1999
    ....
  2. ncbi request reprint Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors
    J M Topczewska
    Department of Cell Biology and Howard Hughes Medical Institute, Vanderbilt Medical Center, Nashville, TN 37232 2175, USA
    Mech Dev 100:343-7. 2001
    ..Early expression of foxc1a in the paraxial mesoderm is modified in chordino, swirl, somitabun, and spadetail mutants...
  3. pmc Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino
    E M Gonzalez
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Genes Dev 14:3087-92. 2000
    ..Thus, a remarkably simple genetic mechanism, involving a coinhibition of BMP function by the partially overlapping bozozok and chordino pathways is used to specify vertebrate head and trunk...
  4. ncbi request reprint Zebrafish nodal-related 2 encodes an early mesendodermal inducer signaling from the extraembryonic yolk syncytial layer
    C E Erter
    Department of Molecular Biology, Vanderbilt University, 1161 21st Avenue South, Nashville, Tennessee, 37232 2175, USA
    Dev Biol 204:361-72. 1998
    ..Our results suggest that znr2 encodes a robust mesendodermal inducer that signals nonautonomously during the earliest stages of embryonic patterning, and that part of this activity arises from within the YSL...
  5. ncbi request reprint Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish
    F Marlow
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    Dev Biol 203:382-99. 1998
    ..Furthermore, tri and kny have overlapping functions in establishing proper alignment of the anterior neural plate and midline cells expressing shh and twhh genes when the partitioning of the eye primordium takes place...
  6. ncbi request reprint The role of the homeodomain protein Bozozok in zebrafish axis formation
    L Solnica-Krezel
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    Int J Dev Biol 45:299-310. 2001
    ..Notably, Bozozok appears to function by repressing transcription of target genes such as swr (bmp2b) gene, and as such is the earliest acting repressor that the nascent dorsal axis is using to antagonize ventral influences...
  7. ncbi request reprint Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension
    D S Sepich
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235 1634, USA
    Genesis 27:159-73. 2000
    ..We propose that trilobite function is required for cell properties that promote increased speed of converging cells and extension movements in the dorsal regions of the zebrafish gastrula...
  8. ncbi request reprint The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension
    J Topczewski
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Dev Cell 1:251-64. 2001
    ....
  9. pmc The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish
    J M Topczewska
    Department of Cell Biology and Howard Hughes Medical Institute, Vanderbilt Medical Center, Nashville, Tennessee 37232 2175, USA
    Genes Dev 15:2483-93. 2001
    ..Therefore, zebrafish foxc1a plays an essential and conserved role in somite formation, regulating both the expression of paraxis and the A/P patterning of somite primordia...
  10. ncbi request reprint Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
    I A Drummond
    Renal Unit, Massachusetts General Hospital, Charlestown MA 02129, USA
    Development 125:4655-67. 1998
    ..These studies reveal the similarity of normal pronephric development to kidney organogenesis in all vertebrates and allow for a genetic dissection of genes needed to establish the earliest renal function...
  11. ncbi request reprint Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo
    C E Erter
    Department of Cell Biology, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232 2175, USA
    Development 128:3571-83. 2001
    ....
  12. ncbi request reprint Mutations affecting development of the notochord in zebrafish
    D L Stemple
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:117-28. 1996
    ....
  13. ncbi request reprint Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation
    H Hashimoto
    Division of Molecular Oncology, Biomedical Research Center, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita, Osaka, 565 0871, Japan
    Dev Biol 217:138-52. 2000
    ..These data indicate that Dkk1, expressed in dorsal mesendoderm, functions in the formation of both the anterior nervous system and the axial mesendoderm in zebrafish...
  14. ncbi request reprint Mutations affecting the development of the embryonic zebrafish brain
    A F Schier
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:165-78. 1996
    ..The identified loci establish the genetic foundation for a further analysis of the development of the zebrafish embryonic brain...
  15. ncbi request reprint Functional interaction of vega2 and goosecoid homeobox genes in zebrafish
    A Kawahara
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genesis 28:58-67. 2000
    ..We suggest that vega2, in cooperation with vega1, functions as a negative regulator of organizer genes including gsc, and participates in the refinement of the gastrula organizer domain...
  16. ncbi request reprint Mutations affecting development of zebrafish digestive organs
    M Pack
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:321-8. 1996
    ..These gastrointestinal mutations may be informative with regard to patterning and crucial lineage decisions during organogenesis, and may be relevant to diabetes, congenital dysmorphogenesis and disorders of cell proliferation...
  17. ncbi request reprint Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish
    L Solnica-Krezel
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:67-80. 1996
    ..These mutations provide an approach to understanding the genetic control of gastrulation in vertebrates...
  18. ncbi request reprint Somites in zebrafish doubly mutant for knypek and trilobite form without internal mesenchymal cells or compaction
    C A Henry
    Department of Zoology, University of Washington, Seattle, 98195 1800, USA
    Curr Biol 10:1063-6. 2000
    ..Thus, intersomitic boundary formation in zebrafish involves short-range movements of presumptive border cells that do not require mechanical forces generated by internal cells or compaction of the presomitic mesoderm...
  19. ncbi request reprint The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of nodal signaling required for organizer formation
    H M Pogoda
    Abteilung für Entwicklungsbiologie, Biologie I, Universitat Freiburg, Hauptstrasse1, D 79104 Freiburg, Germany
    Curr Biol 10:1041-9. 2000
    ..The forkhead transcription factor FoxH1 (also known as Fast1) is a component of the Nodal signaling pathway. Although different roles have been suggested for FoxH1, its specific function during development is still unclear...
  20. ncbi request reprint Mutations affecting neural survival in the zebrafish Danio rerio
    S Abdelilah
    Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
    Development 123:217-27. 1996
    ..The mutations presented here might provide a genetic framework to aid in the understanding of the etiology of degenerative and physiological disorders within the CNS and the activation of inappropriate programmed cell death...
  21. ncbi request reprint Maternal and zygotic activity of the zebrafish ogon locus antagonizes BMP signaling
    V Miller-Bertoglio
    Department of Embryology, Carnegie Institution of Washington, Johns Hopkins University, Baltimore, MD, USA
    Dev Biol 214:72-86. 1999
    ..The results suggest that ogo encodes an as yet unidentified dorsalizing factor that mediates dorsoventral patterning by directly or indirectly antagonizing BMP activity...
  22. ncbi request reprint Mutations affecting development of the zebrafish retina
    J Malicki
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:263-73. 1996
    ....
  23. ncbi request reprint Mutations affecting development of the zebrafish ear
    J Malicki
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:275-83. 1996
    ..Analysis of mutations presented here will strengthen our understanding of vertebrate ear morphogenesis and provide novel entry points to its genetic analysis...
  24. ncbi request reprint Hematopoietic mutations in the zebrafish
    B M Weinstein
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:303-9. 1996
    ..Some cause defects in precursor generation, others defects in differentiation, and others an increase in cellular photosensitivity...
  25. ncbi request reprint A genetic screen for mutations affecting embryogenesis in zebrafish
    W Driever
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129, USA
    Development 123:37-46. 1996
    ..This screen demonstrates that mutations affecting a variety of developmental processes can be efficiently recovered from zebrafish...