D Cizkova

Summary

Affiliation: Slovak Academy of Sciences
Country: Slovakia

Publications

  1. doi request reprint Response of ependymal progenitors to spinal cord injury or enhanced physical activity in adult rat
    Dasa Cizkova
    Institute of Neurobiology, CE, SAS, Kosice, Slovakia
    Cell Mol Neurobiol 29:999-1013. 2009
  2. doi request reprint Enrichment of rat oligodendrocyte progenitor cells by magnetic cell sorting
    D Cizkova
    Institute of Neurobiology, CE SAS, Soltesovej 4 6, 04001 Kosice, Slovakia
    J Neurosci Methods 184:88-94. 2009
  3. doi request reprint Repetitive intrathecal catheter delivery of bone marrow mesenchymal stromal cells improves functional recovery in a rat model of contusive spinal cord injury
    Dasa Cizkova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovakia
    J Neurotrauma 28:1951-61. 2011
  4. ncbi request reprint Transplants of human mesenchymal stem cells improve functional recovery after spinal cord injury in the rat
    Dasa Cizkova
    Institute of Neurobiology, Center of Excellence, SAS, Soltesovej 4, Kosice, 04001, Slovakia
    Cell Mol Neurobiol 26:1167-80. 2006
  5. ncbi request reprint Induction of mesenchymal stem cells leads to HSP72 synthesis and higher resistance to oxidative stress
    Dasa Cizkova
    Tissue culture IHC laboratory, Institute of Neurobiology, Centre of Excellence, SAS, Soltesovej 4, Kosice 04001, Slovakia
    Neurochem Res 31:1011-20. 2006
  6. ncbi request reprint Localization of N-type Ca2+ channels in the rat spinal cord following chronic constrictive nerve injury
    Dasa Cizkova
    Institute of Neurobiology, Slovak Academy of Science, Soltesovej 4, Kosice, 040 01 Kosice, Slovak Republic
    Exp Brain Res 147:456-63. 2002
  7. ncbi request reprint Neuropathic pain is associated with alterations of nitric oxide synthase immunoreactivity and catalytic activity in dorsal root ganglia and spinal dorsal horn
    Dasa Cizkova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovak Republic
    Brain Res Bull 58:161-71. 2002
  8. ncbi request reprint Experimental cauda equina compression induces HSP70 synthesis in dog
    D Cizkova
    Institute of Neurobiology, Slovak Academy of Science, Kosice, Slovak Republic
    Physiol Res 54:349-56. 2005
  9. ncbi request reprint Segmental and laminar distributions of nicotinamide adenine dinucleotide phosphate-diaphorase-expressing and neuronal nitric oxide synthase-immunoreactive neurons versus radioassay detection of catalytic nitric oxide synthase activity in the rabbit spinal
    N Lukacova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovak Republic
    Neuroscience 94:229-37. 1999
  10. doi request reprint IT delivery of ChABC modulates NG2 and promotes GAP-43 axonal regrowth after spinal cord injury
    I Novotna
    Institute of Neurobiology, Slovak Academy of Sciences, Soltesovej 4, 04001 Kosice, Slovakia
    Cell Mol Neurobiol 31:1129-39. 2011

Collaborators

Detail Information

Publications32

  1. doi request reprint Response of ependymal progenitors to spinal cord injury or enhanced physical activity in adult rat
    Dasa Cizkova
    Institute of Neurobiology, CE, SAS, Kosice, Slovakia
    Cell Mol Neurobiol 29:999-1013. 2009
    ..These data demonstrate that SCI or enhanced physical activity in adult rats induces an endogenous ependymal cell response leading to increased proliferation and differentiation primarily into macroglia or cells with nestin phenotype...
  2. doi request reprint Enrichment of rat oligodendrocyte progenitor cells by magnetic cell sorting
    D Cizkova
    Institute of Neurobiology, CE SAS, Soltesovej 4 6, 04001 Kosice, Slovakia
    J Neurosci Methods 184:88-94. 2009
    ..These experiments indicate that MACs technology provide a feasible approach for experimental cell enrichment of desired oligodendroglial progeny, which may be used in future trials for cell-based therapies to treat spinal cord injury...
  3. doi request reprint Repetitive intrathecal catheter delivery of bone marrow mesenchymal stromal cells improves functional recovery in a rat model of contusive spinal cord injury
    Dasa Cizkova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovakia
    J Neurotrauma 28:1951-61. 2011
    ..These results suggest that repetitive IT transplantation, which imposes a minimal burden on the animals, may improve behavioral function when the dose, timing, and targeted IT delivery of MSCs towards the lesion cavity are optimized...
  4. ncbi request reprint Transplants of human mesenchymal stem cells improve functional recovery after spinal cord injury in the rat
    Dasa Cizkova
    Institute of Neurobiology, Center of Excellence, SAS, Soltesovej 4, Kosice, 04001, Slovakia
    Cell Mol Neurobiol 26:1167-80. 2006
    ..In addition, low immunogenicity of hMSCs was confirmed by survival of donor cells without immunosuppressive treatment...
  5. ncbi request reprint Induction of mesenchymal stem cells leads to HSP72 synthesis and higher resistance to oxidative stress
    Dasa Cizkova
    Tissue culture IHC laboratory, Institute of Neurobiology, Centre of Excellence, SAS, Soltesovej 4, Kosice 04001, Slovakia
    Neurochem Res 31:1011-20. 2006
    ..In addition, our findings confirm that cultured rMSCs remain competent to be preconditioned by BME, through a pathway that may increase the antioxidant balance or involve activation of HSP72 protein induced tolerance...
  6. ncbi request reprint Localization of N-type Ca2+ channels in the rat spinal cord following chronic constrictive nerve injury
    Dasa Cizkova
    Institute of Neurobiology, Slovak Academy of Science, Soltesovej 4, Kosice, 040 01 Kosice, Slovak Republic
    Exp Brain Res 147:456-63. 2002
    ..These data suggest that upregulation of the spinal alpha(1B)-subunit may play an important role in the initiation and maintenance of pain state after peripheral nerve injury...
  7. ncbi request reprint Neuropathic pain is associated with alterations of nitric oxide synthase immunoreactivity and catalytic activity in dorsal root ganglia and spinal dorsal horn
    Dasa Cizkova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovak Republic
    Brain Res Bull 58:161-71. 2002
    ..The results indicate that marked alterations of nNOS in the DRG cells and in the spinal cord may contribute to spinal sensory processing as well as to the development of neuronal plasticity phenomena in the dorsal horn...
  8. ncbi request reprint Experimental cauda equina compression induces HSP70 synthesis in dog
    D Cizkova
    Institute of Neurobiology, Slovak Academy of Science, Kosice, Slovak Republic
    Physiol Res 54:349-56. 2005
    ..This suggests that HSP70 may play an active role in neuroprotective processes partly by maintaining intracellular protein integrity and preventing the neuronal degeneration in this experimental paradigm...
  9. ncbi request reprint Segmental and laminar distributions of nicotinamide adenine dinucleotide phosphate-diaphorase-expressing and neuronal nitric oxide synthase-immunoreactive neurons versus radioassay detection of catalytic nitric oxide synthase activity in the rabbit spinal
    N Lukacova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovak Republic
    Neuroscience 94:229-37. 1999
    ....
  10. doi request reprint IT delivery of ChABC modulates NG2 and promotes GAP-43 axonal regrowth after spinal cord injury
    I Novotna
    Institute of Neurobiology, Slovak Academy of Sciences, Soltesovej 4, 04001 Kosice, Slovakia
    Cell Mol Neurobiol 31:1129-39. 2011
    ....
  11. ncbi request reprint Fos protein expression in sacral spinal cord in relation to early phase of cauda equina syndrome in dogs
    J Orendacova
    Institute of Neurobiology, SAS, Kosice, Slovak Republic
    Cell Mol Neurobiol 21:413-9. 2001
    ..e., fibers of sacral primary afferents, unlike those using various stimulations of the peripheral fibres offers an unusual pattern of Fos-like immunoreactivity...
  12. ncbi request reprint Cauda equina syndrome
    J Orendacova
    Institute of Neurobiology, Slovak Academy of Sciences, 040 01 Kosice, Slovak Republic
    Prog Neurobiol 64:613-37. 2001
    ..Developments in the diagnosis and treatment of patients with back pain, sciatica and with a herniated lumbar disc are mentioned, including many treatment options available...
  13. ncbi request reprint Effect of midthoracic spinal cord constriction on catalytic nitric oxide synthase activity in the white matter columns of rabbit
    N Lukacova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovak Republic
    Neurochem Res 25:1139-48. 2000
    ....
  14. ncbi request reprint A simple and reproducible model of spinal cord injury induced by epidural balloon inflation in the rat
    I Vanicky
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovak Republic
    J Neurotrauma 18:1399-407. 2001
    ..We conclude that 15 microl volume produced submaximal injury that will be useful for studying the pathophysiology and effects of protective therapies with this compression-injury model...
  15. ncbi request reprint Chondroitinase ABC treatment and the phenotype of neural progenitor cells isolated from injured rat spinal cord
    L Slovinska
    Institute of Neurobiology, CE, Slovak Academy of Sciences, Kosice, Slovakia
    Physiol Res 60:705-8. 2011
    ..The present findings indicate that the impact of SCI resulted in a decrease of all NPCs phenotypes and the ChABC treatment, on the contrary, caused an opposite effect...
  16. pmc Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells
    D Cizkova
    Institute of Neurobiology, Centrum of Excellence, Slovak Academy of Science, Kosice, Soltesovej 4, Slovakia
    Neuroscience 147:546-60. 2007
    ..These data indicate that spinal grafting of hSSCs can represent an effective therapy for patients with spinal ischemic paraplegia...
  17. ncbi request reprint Cauda equina syndrome and nitric oxide synthase immunoreactivity in the spinal cord of the dog
    J Marsala
    Institute of Neurobiology, Slovak Academy of Sciences, Soltesovej 4, 040 01 Kosice, Slovak Republic
    Physiol Res 52:481-96. 2003
    ....
  18. ncbi request reprint Fluoro-Jade B evidence of induced ischemic tolerance in the rat spinal cord ischemia: physiological, neurological and histopathological consequences
    J Orendacova
    Institute of Neurobiology, Center of Excellence, Slovak Academy of Sciences, Soltesovej 4, 040 01 Kosice, Slovakia
    Gen Physiol Biophys 24:75-87. 2005
    ..Our results are consistent with the previously published silver impregnation method for histopathological demonstration of ischemic degeneration...
  19. ncbi request reprint Time course of brain neuronal degeneration and heat shock protein (72) expression following neck tourniquet-induced cerebral ischemia in the rat
    D Cizkova
    Institute of Neurobiology, SAS, Kosice, Slovak Republic
    Cell Mol Neurobiol 20:367-81. 2000
    ....
  20. doi request reprint Longitudinal enlargement of the lesion after spinal cord injury in the rat: a consequence of malignant edema?
    P Tomko
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovakia
    Spinal Cord . 2016
    ..Experimental animal study...
  21. pmc Delivery of Alginate Scaffold Releasing Two Trophic Factors for Spinal Cord Injury Repair
    I Grulova
    Institute of Neurobiology, Center of Excellence for Brain Research, Department of Regenerative Medicine and Stem Cell Therapy, Slovak Academy of Sciences, Soltesovej 4 6, 040 01 Kosice, Slovakia
    Sci Rep 5:13702. 2015
    ....
  22. ncbi request reprint Long-term changes of c-Fos expression in the rat spinal cord following chronic constriction injury
    Stanislava Jergova
    Institute of Neurobiology, Slovak Academy of Sciences, Kosice
    Eur J Pain 9:345-54. 2005
    ..Our results suggest that, at least in the CCI model, the c-Fos protein expression should not be considered as a reliable index of pain sensation disorders...
  23. ncbi request reprint Effects of chronic intrathecal infusion of a partial differential opioid agonist in dogs
    Kjersti Horais
    Department of Anesthesiology, University of California, San Diego, San Diego, California 92103, USA
    Toxicol Sci 71:263-75. 2003
    ..6 +/- 4.0 micro g/ml for 3 mg/ml and 6 mg/ml infusions respectively. These results indicate that this partial differential opioid agonist DPDPE produces a concentration and time-dependent formation of an intrathecal inflammatory mass...
  24. ncbi request reprint Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat
    Joho Tokumine
    Department of Anesthesiology, Faculty of Medicine, University of the Ryukyus, Japan
    J Neurosci Res 74:552-61. 2003
    ..Increased astrocyte-derived BDNF/GDNF expression corresponds with transient activation of astrocytes and may play an active role in neuronal plasticity after non-injurious intervals of spinal ischemia...
  25. ncbi request reprint Synaptogenesis and amino acid release from long term embryonic rat spinal cord neuronal culture using tissue culture inserts
    Martin Marsala
    Anesthesiology Research Laboratory 0818, 9500 Gilman Drive, University of California, San Diego, La Jolla, CA 92093, USA
    J Neurosci Methods 141:21-7. 2005
    ....
  26. ncbi request reprint Expression of c-Fos in the parabrachial nucleus following peripheral nerve injury in rats
    Stanislava Jergova
    Institute of Neurobiology, Centre of Excellence, Slovak Academy of Sciences, Soltesovej 4, 04001 Kosice, Slovak Republic
    Eur J Pain 12:172-9. 2008
    ..The specific activation of brain stem neurons during onset of mechanical allodynia could underlie the changes in central nociceptive processing following peripheral nerve injury...
  27. ncbi request reprint Region-specific cell grafting into cervical and lumbar spinal cord in rat: a qualitative and quantitative stereological study
    Osamu Kakinohana
    Anesthesiology Research Laboratory, University of California San Diego 0818, La Jolla, CA 92093, USA
    Exp Neurol 190:122-32. 2004
    ..Good survival of implanted cells for the three different cell lines used indicate that this grafting technique coupled with a systematic analysis of the individual grafting sites can represent a valuable implantation-analytical system...
  28. ncbi request reprint Spinal implantation of hNT neurons and neuronal precursors: graft survival and functional effects in rats with ischemic spastic paraplegia
    Martin Marsala
    Department of Anaesthesiology 0818, University of California, San Diego, CA 92093, USA
    Eur J Neurosci 20:2401-14. 2004
    ....
  29. ncbi request reprint Safety evaluation of intrathecal substance P-saporin, a targeted neurotoxin, in dogs
    Jeffrey W Allen
    Department of Anesthesiology, University of California, San Diego, La Jolla, California 92093 0818, USA
    Toxicol Sci 91:286-98. 2006
    ..These data indicate no adverse toxicity at doses up to 10 times those necessary for producing loss of superficial NK1r-bearing neurons in a large animal model...
  30. ncbi request reprint Spinal heat shock protein (70) expression: effect of spinal ischemia, hyperthermia (42 degrees C)/hypothermia (27 degrees C), NMDA receptor activation and potassium evoked depolarization on the induction
    Takeshi Sasara
    Department of Anesthesiology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Neurochem Int 44:53-64. 2004
    ..This effect corresponds with the observed ischemic tolerance state induced by short-lasting preconditioning spinal ischemia...
  31. ncbi request reprint A double-lumen intrathecal catheter for studies of modulation of spinal opiate tolerance
    Carol S Hayes
    Department of Anesthesiology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0818, USA
    J Neurosci Methods 126:165-73. 2003
    ..Using the double-lumen catheter model expands the range of possibility for studies of spinal opiate tolerance and spinal drug delivery...
  32. ncbi request reprint Characterization of spinal HSP72 induction and development of ischemic tolerance after spinal ischemia in rats
    Dasa Cizkova
    Institute of Neurobiology, SAS, 040 01 Kosice, Slovak Republic
    Exp Neurol 185:97-108. 2004
    ....