Yl Lo

Summary

Affiliation: Singapore General Hospital
Country: Singapore

Publications

  1. ncbi request reprint The silent period threshold as a measure of corticospinal inhibition
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Clin Neurophysiol 22:176-9. 2005
  2. doi request reprint Motor and somatosensory abnormalities are significant etiological factors for adolescent idiopathic scoliosis
    Y L Lo
    National Neuroscience Institute, Singapore General Hospital, Singapore Duke NUS Graduate Medical School, Singapore Electronic address
    J Neurol Sci 359:117-23. 2015
  3. doi request reprint A comparison study of repetitive transcranial magnetic stimulation for tinnitus treatment in an Asian population
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore Electronic address
    Clin Neurol Neurosurg 119:96-9. 2014
  4. doi request reprint Outcome prediction value of nerve conduction studies for endoscopic carpal tunnel surgery
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Clin Neuromuscul Dis 13:153-8. 2012
  5. ncbi request reprint Pectoral nerve conduction studies: technique in healthy subjects and evaluation of brachial plexopathy
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    Arch Phys Med Rehabil 86:1702-5. 2005
  6. ncbi request reprint Magnetic brainstem stimulation of the hypoglossal nerve in normal subjects
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore, Singapore
    Eur J Neurol 13:419-22. 2006
  7. ncbi request reprint Presynaptic neuromuscular transmission defect in the Miller Fisher syndrome
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    Neurology 66:148-9. 2006
  8. ncbi request reprint Transcranial magnetic stimulation screening for cord compression in cervical spondylosis
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore 169608, Singapore
    J Neurol Sci 244:17-21. 2006
  9. ncbi request reprint Superficial peroneal sensory and sural nerve conduction studies in peripheral neuropathy
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    J Clin Neurosci 13:547-9. 2006
  10. ncbi request reprint Intraoperative motor-evoked potential monitoring in scoliosis surgery: comparison of desflurane/nitrous oxide with propofol total intravenous anesthetic regimens
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Neurosurg Anesthesiol 18:211-4. 2006

Collaborators

Detail Information

Publications54

  1. ncbi request reprint The silent period threshold as a measure of corticospinal inhibition
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Clin Neurophysiol 22:176-9. 2005
    ..Its value was significantly lower with left-sided transcranial magnetic stimulation and right-hand recordings. The silent period threshold may be a novel parameter useful for future studies of cortical inhibitory function...
  2. doi request reprint Motor and somatosensory abnormalities are significant etiological factors for adolescent idiopathic scoliosis
    Y L Lo
    National Neuroscience Institute, Singapore General Hospital, Singapore Duke NUS Graduate Medical School, Singapore Electronic address
    J Neurol Sci 359:117-23. 2015
    ..In adolescent idiopathic scoliosis (AIS), we explore the role of lateralized motor and somatosensory abnormalities as a possible etiological factor...
  3. doi request reprint A comparison study of repetitive transcranial magnetic stimulation for tinnitus treatment in an Asian population
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore Electronic address
    Clin Neurol Neurosurg 119:96-9. 2014
    ..Tinnitus, a subjective auditory perception of sounds or noise not triggered by external auditory stimuli, carries considerable morbidity. To date, pharmacological, physical or behavioral therapy is the mainstay of management...
  4. doi request reprint Outcome prediction value of nerve conduction studies for endoscopic carpal tunnel surgery
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Clin Neuromuscul Dis 13:153-8. 2012
    ..Carpal tunnel syndrome is the most common entrapment neuropathy. We explore the clinical use of nerve conduction study in the outcome prediction and preoperative selection for endoscopic carpal tunnel syndrome surgery...
  5. ncbi request reprint Pectoral nerve conduction studies: technique in healthy subjects and evaluation of brachial plexopathy
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    Arch Phys Med Rehabil 86:1702-5. 2005
    ..To define the optimal nerve conduction study (NCS) technique of the pectoral nerves and evaluate its clinical utility...
  6. ncbi request reprint Magnetic brainstem stimulation of the hypoglossal nerve in normal subjects
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore, Singapore
    Eur J Neurol 13:419-22. 2006
    ..Our findings suggest activation at or distal to the hypoglossal nuclear level, but proximal to the hypoglossal canal region. Our method can be usefully applied in future studies of brainstem and cranial nerve function...
  7. ncbi request reprint Presynaptic neuromuscular transmission defect in the Miller Fisher syndrome
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    Neurology 66:148-9. 2006
  8. ncbi request reprint Transcranial magnetic stimulation screening for cord compression in cervical spondylosis
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore 169608, Singapore
    J Neurol Sci 244:17-21. 2006
    ..Cervical spondylosis (CS) often results in various degrees of cord compression, which can be evaluated functionally with transcranial magnetic stimulation (TMS). We investigate the use of TMS as a screening tool for myelopathy in CS...
  9. ncbi request reprint Superficial peroneal sensory and sural nerve conduction studies in peripheral neuropathy
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    J Clin Neurosci 13:547-9. 2006
    ..5%) was significantly higher (P<0.001) compared with sural NCS (75%). The superficial peroneal NCS appeared to have a higher detection rate for peripheral neuropathy in our study, and its study can be adjunctive to sural NCS...
  10. ncbi request reprint Intraoperative motor-evoked potential monitoring in scoliosis surgery: comparison of desflurane/nitrous oxide with propofol total intravenous anesthetic regimens
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Neurosurg Anesthesiol 18:211-4. 2006
    ..A prospective, randomized study in a large general hospital setting...
  11. pmc Intraoperative monitoring study of ipsilateral motor evoked potentials in scoliosis surgery
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore, Singapore
    Eur Spine J 15:656-60. 2006
    ..The possible underlying mechanisms are discussed based on current knowledge of corticospinal pathways. Ipsilateral MEPs may provide additional information on the integrity of descending motor tracts during spinal surgery monitoring...
  12. ncbi request reprint Magnetic brainstem stimulation of the facial nerve
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Clin Neurophysiol 24:44-7. 2007
    ..Our findings suggest activation of descending facial fibers proximal to brainstem motoneurons. This method is advocated as an adjunct in the electrodiagnostic workup of facial nerve dysfunction...
  13. ncbi request reprint Cutaneous silent periods in the evaluation of cord compression in cervical spondylosis
    Y L Lo
    Dept of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore
    J Neurol 254:14-9. 2007
    ..The clinical diagnosis of cervical spondylotic myelopathy (CSM) may be challenging in patients with cervical spondylosis (CS). Routine nerve conduction studies (NCS) may not evaluate cord compression adequately...
  14. pmc The value of bilateral ipsilateral and contralateral motor evoked potential monitoring in scoliosis surgery
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, Singapore 169608
    Eur Spine J 17:S236-8. 2008
    ..The use of this easily recordable MEP is thus advocated as a diagnostic adjunct to contralateral MEPs for scoliosis and spinal surgery...
  15. ncbi request reprint Diagnostic utility of F waves in cervical radiculopathy: electrophysiological and magnetic resonance imaging correlation
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    Clin Neurol Neurosurg 110:58-61. 2008
    ..F wave study is a simple, non-invasive method commonly utilized for evaluation of cervical root lesions. Its diagnostic sensitivity is low. There are no large series comparing F wave studies with MRI as a reference standard...
  16. doi request reprint Cerebellar control of motor activation and cancellation in humans: an electrophysiological study
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore
    Cerebellum 8:302-11. 2009
    ..Our findings contribute to the understanding of cerebellar neural networks involvement in movements, in particular, those pertaining to cessation of an ongoing action not previously addressed...
  17. doi request reprint Electrophysiological evidence of cerebellar fiber system involvement in the Miller Fisher syndrome
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Neurol Sci 288:49-53. 2010
    ..In the Miller Fisher syndrome (MFS), ataxia may be due involvement of Ia afferents and the cerebellum. Transcranial magnetic stimulation (TMS) over the cerebellum is known to interfere transiently with normal function...
  18. pmc A pilot study of topiramate dosages for migraine prophylaxis in an Asian population
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, Singapore
    J Headache Pain 11:175-8. 2010
    ..Here, we show that a fixed low dose of topiramate 25 mg/day is efficacious in migraine prophylaxis and also attest to advantages in terms of medication cost savings and more favourable side effect profile...
  19. doi request reprint High-resolution ultrasound in the evaluation and prognosis of Bell's palsy
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    Eur J Neurol 17:885-9. 2010
    ..Ultrasound (US) may provide a novel approach for evaluating and prognosticating Bell's palsy, in comparison with known electrophysiological techniques...
  20. pmc Clinical and physiological effects of transcranial electrical stimulation position on motor evoked potentials in scoliosis surgery
    Yl Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    Scoliosis 5:3. 2010
    ..We tested this hypothesis using two stimulating positions. We compared intraoperative MEPs in 14 neurologically normal subjects undergoing scoliosis surgery using total intravenous anesthetic regimens...
  21. doi request reprint A study of acupuncture in Asian patients: clinical aspects and effects on cortical excitability
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore 169608, Singapore
    Acupunct Med 28:74-7. 2010
    ..To determine the effect of acupuncture on the phosphene threshold, by transcranial magnetic stimulation (TMS), and the clinical effect of acupuncture on headache frequency, duration and severity...
  22. doi request reprint Motor root conduction block in the Lewis-Sumner syndrome
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Clin Neuromuscul Dis 12:158-62. 2011
    ..The Lewis-Sumner syndrome (LSS) is a rare immune-mediated peripheral nerve disorder presenting with asymmetric upper limb sensory complaints and motor weakness. Asian patients with LSS have not been reported in the English literature...
  23. pmc Auditory hallucinations and migraine of possible brainstem origin
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore
    J Headache Pain 12:573-5. 2011
    ..Concurrence of migraine and hallucinations is extremely rare and the underlying mechanism is poorly understood...
  24. ncbi request reprint Effect of exercise on repetitive nerve stimulation studies: new appraisal of an old technique
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Clin Neurophysiol 21:110-3. 2004
    ..4% compared with conventional 3-Hz RNS at rest. The standardized use of exercise with RNS is advocated for increasing its diagnostic yield in the neurophysiologic laboratory...
  25. ncbi request reprint Clinical and electrophysiological aspects of distal ulnar neuropathy
    Yew Long Lo
    Department of Neurology, Singapore General Hospital, Outram Road, Singapore 169608
    Acta Neurol Scand 105:390-4. 2002
    ..To evaluate the use of fixed distance side to side comparison of abductor digiti minimi (ADM) and first dorsal interosseous (FDI) compound muscle action potential (CMAP) studies in the diagnosis of distal ulnar neuropathy...
  26. ncbi request reprint Repetitive hypoglossal nerve stimulation in myasthenia gravis
    Y L Lo
    Department of Neurology, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    Clin Neurophysiol 113:1227-30. 2002
    ..To assess the diagnostic efficacy of repetitive nerve stimulation (RNS) of the hypoglossal nerve in patients with myasthenia gravis (MG) and bulbar symptoms (dysphagia, dysarthria)...
  27. pmc Repetitive stimulation of the long thoracic nerve in myasthenia gravis: clinical and electrophysiological correlations
    Y L Lo
    Department of Neurology, Singapore General Hospital, Singapore
    J Neurol Neurosurg Psychiatry 74:379-81. 2003
    ..To investigate repetitive stimulation of the long thoracic nerve as a reliable and technically undemanding method for evaluating respiratory muscle function in myasthenia gravis...
  28. ncbi request reprint Statin therapy and small fibre neuropathy: a serial electrophysiological study
    Y L Lo
    Department of Neurology, Singapore General Hospital, Outram Road, Singapore
    J Neurol Sci 208:105-8. 2003
    ..One patient redeveloped small and large fibre neuropathy when the similar drug was readministered. The SSR is of value in the electrophysiological assessment and follow-up of statin-related small fibre neuropathy...
  29. ncbi request reprint Decrement in area of muscle responses to repetitive nerve stimulation
    Y L Lo
    Department of Neurology, Singapore General Hospital, Outram Road, Singapore
    Muscle Nerve 27:494-6. 2003
    ..Decrement of response area provided additional diagnostic yields of 5.3% to 30% depending on the muscle examined and disease severity, and is recommended as a diagnostic adjunct to measurement of amplitude decrement during RNS...
  30. ncbi request reprint Acupuncture and the modulation of cortical excitability
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore 169608
    Neuroreport 14:1229-31. 2003
    ..These findings provide new neurophysiological evidence of cortical excitability modulation complementary to findings derived from functional neuroimaging studies...
  31. ncbi request reprint Corticobulbar dysfunction in the Miller Fisher syndrome
    Y L Lo
    Department of Neurology, Singapore General Hospital, Outram Road, 169608, Singapore, Singapore
    Clin Neurol Neurosurg 105:156-8. 2003
    ..Transcranial magnetic stimulation studies give an evidence of a reversible corticobulbar conduction abnormality which resolved with clinical improvement...
  32. ncbi request reprint Cortical excitability changes associated with musical tasks: a transcranial magnetic stimulation study in humans
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 160608, Singapore
    Neurosci Lett 352:85-8. 2003
    ..The findings complement those from neuroimaging and support the existence of separate bilateral deep-seated neural networks, as distinct from those for vocalization...
  33. ncbi request reprint An electrophysiological study of the deep peroneal sensory nerve
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    Eur Neurol 50:244-7. 2003
    ....
  34. pmc Acute ophthalmoparesis in the anti-GQ1b antibody syndrome: electrophysiological evidence of neuromuscular transmission defect in the orbicularis oculi
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Neurol Neurosurg Psychiatry 75:436-40. 2004
    ..To prospectively study anti-GQ1b antibody positive cases of acute ophthalmoparesis (AO) clinically and electrophysiologically...
  35. ncbi request reprint Systematic correlation of transcranial magnetic stimulation and magnetic resonance imaging in cervical spondylotic myelopathy
    Y L Lo
    Department of Neurology, Singapore General Hospital, Singapore
    Spine (Phila Pa 1976) 29:1137-45. 2004
    ..A prospective study over a 3.5-year period involving transcranial magnetic stimulation and magnetic resonance imaging...
  36. ncbi request reprint Pectoralis major motor evoked potentials in cervical spondylosis
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Neurol Sci 235:55-9. 2005
    ..Our findings show that CMCT measurement with PM recordings is of value as a diagnostic adjunct in the electrophysiological evaluation of myelopathy in CS...
  37. ncbi request reprint Posterior antebrachial cutaneous nerve conduction study in radial neuropathy
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    J Neurol Sci 223:199-202. 2004
    ..Conversely, PACN abnormality was correlated with radial motor axon loss and a poorer prognosis. The PACN study is a simple adjunct which provides additional information relating to the diagnosis and prognosis of radial lesions...
  38. ncbi request reprint A transcranial magnetic stimulation study of the ipsilateral silent period in lower limb muscles
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    Neurosci Lett 368:337-40. 2004
    ..Our results highlight the feasibilty of eliciting ISPs in the lower limbs, relevant for future studies of interhemispheric interaction in clinical and research settings...
  39. ncbi request reprint Ipsilateral and contralateral motor inhibitory control in musical and vocalization tasks
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, 169608, Singapore, Singapore
    Exp Brain Res 159:258-62. 2004
    ..The findings support the presence of enhanced interhemispheric inhibitory motor interaction during singing, as opposed to reading tasks, in dynamic word generation coupled with production of melody...
  40. ncbi request reprint Overriding fifth finger: an unusual sign in lower brachial plexopathy
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    J Clin Neurosci 11:902-4. 2004
    ..The unusual physical sign occurred in association with neuralgic amyotrophy. Its occurrence can be explained in terms of transient patchy involvement of nerve fascicles in the brachial plexus...
  41. ncbi request reprint Motor root conduction block in traumatic brachial plexopathy
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    J Neurol Sci 227:91-4. 2004
    ..Electrical stimulation demonstrated multilevel motor root conduction block, which reversed after a 4-month period. Motor root conduction studies are useful diagnostic and prognostic adjuncts in the management of brachial plexopathy...
  42. ncbi request reprint Short-segment nerve conduction studies in the localization of ulnar neuropathy of the elbow: use of flexor carpi ulnaris recordings
    Y L Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, 169608, Singapore
    Muscle Nerve 31:633-6. 2005
    ..4% when recording from abductor digiti minimi. The rationale underlying the technique is discussed. This approach should be of value as a diagnostic adjunct in technically challenging cases of ulnar neuropathy at the elbow...
  43. ncbi request reprint The effect of acupuncture on motor cortex excitability and plasticity
    Yew Long Lo
    National Neuroscience Institute, Singapore General Hospital, Department of NeurologyOutram Road, Singapore 169608, Singapore
    Neurosci Lett 384:145-9. 2005
    ....
  44. ncbi request reprint Role of spinal inhibitory mechanisms in whiplash injuries
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    J Neurotrauma 24:1055-67. 2007
    ..The use of this simple, quick, and sensitive method is advocated in the diagnostic work up of whiplash injury...
  45. ncbi request reprint The role of electrophysiology in the diagnosis and management of cervical spondylotic myelopathy
    Yew Long Lo
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore 169608
    Ann Acad Med Singapore 36:886-93. 2007
    ..We have previously established the role of TMS in diagnosis and screening of CSM. In this study, we further investigate the use MEPs obtained with TMS in the outcome prediction of severe CSM patients requiring operative intervention...
  46. ncbi request reprint "Myorhythmia" slow facial tremor from chronic interferon alpha-2a usage
    Eng King Tan
    Department of Neurology, Singapore General Hospital
    Neurology 61:1302-3. 2003
  47. ncbi request reprint Isolated facial myorhythmia
    Eng King Tan
    Department of Neurology, Singapore General Hospital, Singapore
    J Neurol Sci 252:36-8. 2007
    ..However, the pathological basis why the facial region was selectively involved in our patient is unclear. Early recognition of the symptoms and signs would facilitate investigations for an underlying cause...
  48. ncbi request reprint Mixed nerve potentials in brachial plexopathy
    Siew Ju See
    Department of Neurology, Singapore General Hospital, Outram Road, S 169608, Singapore, Singapore
    Clin Neurol Neurosurg 104:16-9. 2002
    ..Eleven out of 14 patients had a Erb's point amplitude ratio less than that of controls. This method is a simple and useful adjunct in the electrophysiological assessment of brachial plexopathy...
  49. ncbi request reprint Acute ataxia, Graves' disease, and stiff person syndrome
    Su Ynn Chia
    Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore
    Mov Disord 22:1969-71. 2007
    ..Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow-up period of 3 years...
  50. pmc Bilateral trapezius hypertrophy with dystonia and atrophy
    Eng King Tan
    Department of Neurology, Singapore General Hospital, National Neuroscience Institute, Singapore
    CMAJ 176:1702-3. 2007
  51. ncbi request reprint Impaired motor imagery in patients with essential tremor: a case control study
    Yew Long Lo
    Department of Neurology, Singapore General Hospital, Singapore
    Mov Disord 22:504-8. 2007
    ..The basis for this novel finding is unclear, and further studies are warranted to determine whether it is related to cerebellar or motor cortical dysfunction...
  52. ncbi request reprint Vocal fold paralysis following radiotherapy for nasopharyngeal carcinoma: laryngeal electromyography findings
    David P C Lau
    Department of Otolaryngology, Singapore General Hospital, Singapore
    J Voice 17:82-7. 2003
    ..This is the first report describing the use of electromyography to determine the pattern of nerve injury in patients with vocal fold paralysis following head and neck radiotherapy...