Nobuhiro Yuki

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. doi request reprint GD1b-specific antibodies may bind to complex of GQ1b and GM1, causing ataxia
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Neurol 261:1565-9. 2014
  2. doi request reprint Complement activation by anti-GQ1b antibodies in Fisher syndrome and its variants
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Neuroimmunol 258:100-1. 2013
  3. doi request reprint Atypical Bickerstaff brainstem encephalitis: ataxic hypersomnolence without ophthalmoplegia
    Benjamin R Wakerley
    Department of Medicine, National University Hospital, Singapore, Singapore
    J Neurol Neurosurg Psychiatry 84:1206-7. 2013
  4. doi request reprint Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?
    Kazuki Miyaji
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Hum Immunol 75:1089-91. 2014
  5. doi request reprint Sialylated IgG-Fc: a novel biomarker of chronic inflammatory demyelinating polyneuropathy
    Anna Hiu Yi Wong
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Neurol Neurosurg Psychiatry 87:275-9. 2016
  6. doi request reprint Autoantibodies to tetraspanins (CD9, CD81 and CD82) in demyelinating diseases
    Kazuki Miyaji
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Neuroimmunol 291:78-81. 2016
  7. doi request reprint Acute and chronic ataxic neuropathies with disialosyl antibodies: a continuous clinical spectrum and a common pathophysiological mechanism
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Unit 09 01, 14 Medical Drive, 117599, Singapore
    Muscle Nerve 49:629-35. 2014
  8. doi request reprint Pharyngeal-cervical-brachial variant of Guillain-Barre syndrome
    Benjamin R Wakerley
    Department of Medicine, National University Hospital, Singapore
    J Neurol Neurosurg Psychiatry 85:339-44. 2014
  9. doi request reprint Lower motor neuron syndrome associated with IgG anti-GM1 antibodies revisited
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Neuroimmunol 272:62-6. 2014
  10. doi request reprint Non-demyelinating, reversible conduction failure in Fisher syndrome and related disorders
    Thirugnanam Umapathi
    Department of Neurology, National Neuroscience Institute, Singapore, Singapore
    J Neurol Neurosurg Psychiatry 83:941-8. 2012

Collaborators

  • Nortina Shahrizaila
  • Norito Kokubun
  • Jérôme J Devaux
  • Masahiro Mori
  • Yee Cheun Chan
  • Kazuki Miyaji
  • Benjamin R Wakerley
  • Anna Hiu Yi Wong
  • Thirugnanam Umapathi
  • Yuki Fukami
  • Makoto Sudo
  • Friedemann Paul
  • Yumako Miura
  • Hwee Li Yeo
  • Amy May Lin Quek
  • Derek Soon
  • Einar Wilder-Smith
  • Shinsuke Hamada
  • Nurul M Sainuddin
  • Aravind Kannan Therimadasamy
  • Constance Manso
  • Chi Wai Lee
  • Jorain Yu Ni Lim
  • Maya Belghazi
  • Koichi Hirata
  • Thomas Paulraj Thamboo
  • Kana Matsumoto-Morita
  • Benjamin K Ong
  • Yoshiki Yamaguchi
  • Peter J Späth
  • Aftab Ahmad
  • Prakash Paliwal
  • Kamal Verma
  • Eyok Yian Tan

Detail Information

Publications20

  1. doi request reprint GD1b-specific antibodies may bind to complex of GQ1b and GM1, causing ataxia
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Neurol 261:1565-9. 2014
    ..In conclusion, the GD1b-specific antibodies, which recognizes GQ1b/GM1 or GT1a/GM1 complex, are associated with acute ataxia...
  2. doi request reprint Complement activation by anti-GQ1b antibodies in Fisher syndrome and its variants
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Neuroimmunol 258:100-1. 2013
    ..In the current in vitro study, we could not demonstrate the association of complement activation with disease extension...
  3. doi request reprint Atypical Bickerstaff brainstem encephalitis: ataxic hypersomnolence without ophthalmoplegia
    Benjamin R Wakerley
    Department of Medicine, National University Hospital, Singapore, Singapore
    J Neurol Neurosurg Psychiatry 84:1206-7. 2013
    ..Clinical and immunological evaluation of 'incomplete' Bickerstaff brainstem encephalitis (BBE)...
  4. doi request reprint Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?
    Kazuki Miyaji
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Hum Immunol 75:1089-91. 2014
    ..Ezrin, radixin and moesin are unlikely targets for autoantibodies in AIDP and CIDP, and the association of anti-moesin antibodies with cytomegalovirus-related AIDP was not confirmed. ..
  5. doi request reprint Sialylated IgG-Fc: a novel biomarker of chronic inflammatory demyelinating polyneuropathy
    Anna Hiu Yi Wong
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Neurol Neurosurg Psychiatry 87:275-9. 2016
    ..We aim to test whether IgG-Fc sialylation is a biomarker of disease activity for chronic inflammatory demyelinating polyneuropathy (CIDP)...
  6. doi request reprint Autoantibodies to tetraspanins (CD9, CD81 and CD82) in demyelinating diseases
    Kazuki Miyaji
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Neuroimmunol 291:78-81. 2016
    ..It is unlikely that these autoantibodies are pathogenic or serve as potential biomarkers in demyelinating diseases. ..
  7. doi request reprint Acute and chronic ataxic neuropathies with disialosyl antibodies: a continuous clinical spectrum and a common pathophysiological mechanism
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Unit 09 01, 14 Medical Drive, 117599, Singapore
    Muscle Nerve 49:629-35. 2014
    ....
  8. doi request reprint Pharyngeal-cervical-brachial variant of Guillain-Barre syndrome
    Benjamin R Wakerley
    Department of Medicine, National University Hospital, Singapore
    J Neurol Neurosurg Psychiatry 85:339-44. 2014
    ..In this review, we highlight the clinical features of PCB and outline new diagnostic criteria. ..
  9. doi request reprint Lower motor neuron syndrome associated with IgG anti-GM1 antibodies revisited
    Nobuhiro Yuki
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Neuroimmunol 272:62-6. 2014
    ..Both IgM and IgG anti-GM1 antibodies should be tested in patients who have lower motor neuron syndrome. ..
  10. doi request reprint Non-demyelinating, reversible conduction failure in Fisher syndrome and related disorders
    Thirugnanam Umapathi
    Department of Neurology, National Neuroscience Institute, Singapore, Singapore
    J Neurol Neurosurg Psychiatry 83:941-8. 2012
    ..We hypothesised that such reversible conduction failure would be also observed in FS and related disorders...
  11. doi request reprint Non-demyelinating, reversible conduction failure in a case of pharyngeal-cervical-brachial weakness overlapped by Fisher syndrome
    Yee Cheun Chan
    Division of Neurology, Department of Medicine, National University Hospital, Singapore
    J Neurol Sci 321:103-6. 2012
    ....
  12. doi request reprint Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies?
    Kazuki Miyaji
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Neuroimmunol 276:172-4. 2014
    ..These autoantibodies are unlikely to be biomarkers in acute and chronic inflammatory demyelinating polyneuropathies. ..
  13. doi request reprint Acute-onset chronic inflammatory demyelinating polyneuropathy with focal segmental glomerulosclerosis
    Amy May Lin Quek
    Department of Medicine, National University Health System, Singapore
    J Neurol Sci 341:139-43. 2014
    ..Literature review of cases of concurrent inflammatory neuropathies and nephrotic syndrome revealed similar neuro-renal presentations. This neuro-renal condition may be mediated by autoantibodies targeting myelin and podocytes. ..
  14. doi request reprint Infectious and noninfectious triggers in Guillain-Barré syndrome
    Benjamin R Wakerley
    Department of Medicine, National University Hospital, 1E Kent Ridge Road, Singapore
    Expert Rev Clin Immunol 9:627-39. 2013
    ....
  15. doi request reprint Using Xenopus tissue cultures for the study of myasthenia gravis pathogenesis
    Hwee Li Yeo
    Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
    Dev Biol 408:244-51. 2015
    ....
  16. doi request reprint Autoimmune inflammatory neuropathies: updates in pathogenesis, diagnosis, and treatment
    Anna Hiu Yi Wong
    aDepartment of Medicine bDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore cBrain and Mind Research Institute, The University of Sydney
    Curr Opin Neurol 28:468-73. 2015
    ..The present review aims at discussing the recent advances in pathogenesis, diagnosis, and treatment of major subtypes of autoimmune inflammatory neuropathies...
  17. doi request reprint Serial electrophysiological studies in a Guillain-Barré subtype with bilateral facial neuropathy
    Yee Cheun Chan
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore Division of Neurology, National University Hospital, Singapore Electronic address
    Clin Neurophysiol 127:1694-9. 2016
    ..We retrospectively analyzed the changes on serial NCS of patients with bilateral facial neuropathy...
  18. pmc Different IVIG glycoforms affect in vitro inhibition of anti-ganglioside antibody-mediated complement deposition
    Makoto Sudo
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    PLoS ONE 9:e107772. 2014
    ..Therefore, sialylated and galactosylated IVIGs may be more effective than conventional IVIG in the treatment of complement-dependent autoimmune diseases. ..
  19. pmc Contactin 1 IgG4 associates to chronic inflammatory demyelinating polyneuropathy with sensory ataxia
    Yumako Miura
    1 Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Brain 138:1484-91. 2015
    ..Anti-contactin 1 IgG4 antibodies are a possible biomarker to guide treatment option. ..
  20. pmc Guillain-Barré syndrome and anti-ganglioside antibodies: a clinician-scientist's journey
    Nobuhiro Yuki
    Department of Medicine, National University of Singapore, Singapore
    Proc Jpn Acad Ser B Phys Biol Sci 88:299-326. 2012
    ..In this review, I wanted to share my journey from being a clinician to a clinician-scientist in the hopes of inspiring younger clinicians to follow a similar path...