Dale A Fisher
Affiliation: National University of Singapore
- Outpatient parenteral antibiotic therapy (OPAT) in Asia: missing an opportunityDale Fisher
Infectious Disease Division, Department of Medicine, National University Hospital, Singapore
J Antimicrob Chemother . 2017..In that survey we also sought to explore the capacity and interest of these facilities in developing systematized OPAT services...
- Medicine and the future of health: reflecting on the past to forge aheadDale Fisher
Infectious Disease Division, Department of Medicine, National University Hospital National University Health Systems, 1E Kent Ridge Rd, Singapore, 119228, Singapore
BMC Med 14:169. 2016..The Medicine and the Future of Health article collection is a joint collection between BMC Medicine and Journal of Pharmaceutical Policy and Practice. Therefore, this Editorial by the guest editors has been published in both journals...
- Progression from new methicillin-resistant Staphylococcus aureus colonisation to infection: an observational study in a hospital cohortMichelle N D Balm
Infection Control Team, National University Hospital, Singapore, Singapore
BMC Infect Dis 13:491. 2013..At present, there are limited data on the duration or magnitude of this risk in a hospital population with a known time of MRSA acquisition...
- Sustained meticillin-resistant Staphylococcus aureus control in a hyper-endemic tertiary acute care hospital with infrastructure challenges in SingaporeD Fisher
Department of Medicine, National University Health System, Singapore Yong Loo Lin School of Medicine, National University of Singapore, Singapore Infection Control Team, National University Health System, Singapore Electronic address
J Hosp Infect 85:141-8. 2013..Approximately 5% of our hospital beds are used as isolation facilities...
- Automated measures of hand hygiene compliance among healthcare workers using ultrasound: validation and a randomized controlled trialDale A Fisher
Department of Medicine, National University Health System, Singapore
Infect Control Hosp Epidemiol 34:919-28. 2013..The secondary objective was to assess the impact of audio reminders and quantified individual feedback...
- Outpatient parenteral antibiotic therapy in SingaporeD A Fisher
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Int J Antimicrob Agents 28:545-50. 2006..Our three services have evolved independently into very similar practices. There is potential for further innovation, including outreach and carer-delivered dosing. However, major financial disincentives require review...
- Confirmed adult dengue deaths in Singapore: 5-year multi-center retrospective studyYee Sin Leo
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore
BMC Infect Dis 11:123. 2011..A new WHO 2009 guideline emphasized warning signs and a wider range of severe dengue manifestations. We aim to evaluate the utility of these two guidelines in confirmed adult dengue fatalities...
- Methicillin-resistant Staphylococcus aureus control in Singapore: moving forwardLynette A Pereira
Yong Loo Lin School of Medicine, National University Singapore, Singapore
Ann Acad Med Singapore 37:891-6. 2008..Currently, efforts are evolving significantly and today, we have a good opportunity to embark on this difficult journey. Implementing infection control initiatives successfully over the next few years will save lives in the future...
- Nephrotoxicity of continuous versus intermittent infusion of vancomycin in outpatient parenteral antimicrobial therapyPaul R Ingram
Department of Medicine, National University Hospital, Singapore Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Int J Antimicrob Agents 34:570-4. 2009..Both groups received a similar cumulative vancomycin dose. In adult OPAT patients with normal renal function, vancomycin CI was associated with a slower onset of nephrotoxicity...
- A cost analysis of Outpatient Parenteral Antibiotic Therapy (OPAT): an Asian perspectiveCandice Yong
Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, 117543 Singapore, Singapore
Int J Antimicrob Agents 33:46-51. 2009..001). There was no difference in outcomes between the two groups. OPAT is a viable alternative to inpatient care as it is safe, effective and results in lower daily costs. The trend to longer treatment courses is worthy of further review...
- Efficacy of continuous infusion of vancomycin for the outpatient treatment of methicillin-resistant Staphylococcus aureus infectionsAyesha J Verrall
University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
J Antimicrob Chemother 67:2970-3. 2012..We compared outcomes of patients treated with continuous infusion and intermittent infusion of vancomycin...
- Ertapenem in outpatient parenteral antimicrobial therapy for complicated urinary tract infectionsMohamad Ali Trad
a Division of Infectious Diseases, University Medicine Cluster, National University Hospital, Singapore, Singapore
J Chemother . 2016..We assessed the microbiological and clinical cure rates associated with ertapenem treatment for cUTIs in two outpatient parenteral antimicrobial therapy (OPAT) departments...
- Risk factors for nephrotoxicity associated with continuous vancomycin infusion in outpatient parenteral antibiotic therapyPaul R Ingram
Department of Medicine, National University Hospital, Singapore
J Antimicrob Chemother 62:168-71. 2008..We investigated the risk factors associated with nephrotoxicity in this setting...
- Cost-effectiveness analysis of hospital infection control response to an epidemic respiratory virus threatYock Young Dan
National University Health System, Singapore
Emerg Infect Dis 15:1909-16. 2009..A calibrated approach in accordance with viral characteristics and community risks may help refine responses to future epidemics...
- The global spread of healthcare-associated multidrug-resistant bacteria: a perspective from AsiaJames S Molton
Division of Infectious Diseases, National University Health System, Level 10, Department of Medicine, 1E Kent Ridge Road, Singapore 119228
Clin Infect Dis 56:1310-8. 2013..As the antibiotic pipeline offers little in the short term, our most important tools against the spread of antibiotic resistant organisms are intensified infection control, surveillance, and antimicrobial stewardship...
- A novel approach to improve hand hygiene compliance of student nursesSharon Salmon
Infection Control Team, National University Health System, 1E Kent Ridge Rd, Singapore 119228, Singapore
Antimicrob Resist Infect Control 2:16. 2013..The training was based on the World Health Organisation (WHO) "My 5 moments for hand hygiene" approach. Upon completion students completed an anonymous questionnaire to evaluate their learning experience...
- Carbapenems and subsequent multiresistant bloodstream infection: does treatment duration matter?Annabelle D Donaldson
Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
Int J Antimicrob Agents 34:246-51. 2009..Strategies that depend primarily on reducing broad-spectrum antibiotic duration may be inadequate in preventing the emergence of MDR organisms...
- Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virusChen Yu Tsai
Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Republic of Singapore
J Immunol 194:3890-900. 2015....
- Screening for vancomycin-resistant enterococci using stools sent for Clostridium difficile cytotoxin assay is effective: results of a survey of 300 Patients in a large Singapore Teaching HospitalJoshua K X Tay
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Ann Acad Med Singapore 36:926-9. 2007..To assess the efficacy of screening stools sent for Clostridium difficile cytotoxin assay (CDTA) for surveillance of vancomycin-resistant enterococci (VRE)...
- Risk factors for fatality among confirmed adult dengue inpatients in Singapore: a matched case-control studyTun Linn Thein
Communicable Disease Center, Tan Tock Seng Hospital, Singapore, Singapore, Singapore
PLoS ONE 8:e81060. 2013..To identify demographic, clinical and laboratory risk factors for death due to dengue fever in adult patients in Singapore...
- Dengue management: practical and safe hospital-based outpatient carePaul R Ingram
Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
Trans R Soc Trop Med Hyg 103:203-5. 2009..In the first five months, this predominantly nurse-operated, protocol-based clinic enrolled 118 adults, or 35% of patients who would have ordinarily received inpatient care. This resulted in 207 bed-days saved without adverse events...
- Pseudo-outbreak of Rhizobium radiobacter infection resulting from laboratory contamination of saline solutionLynette A Pereira
Yong Loo Lin School of Medicine, National University Singapore, Singapore
J Clin Microbiol 47:2256-9. 2009..The episode resolved with autoclaving of the dispenser. This demonstrates the importance of timely, thorough investigation of unusual organisms, particularly when they appear as a cluster...