National University of Singapore

Summary

Organization: National University of Singapore
Country: Singapore

Top Publications

  1. ncbi Facile patterning of upconversion NaYF4:Yb,Er nanoparticles
    Hua Yan Si
    Department of Materials Science and Engineering, National University of Singapore, Singapore 117540, Republic of Singapore
    J Colloid Interface Sci 353:569-73. 2011
  2. doi Practical application of CellML 1.1: The integration of new mechanisms into a human ventricular myocyte model
    David Nickerson
    Division of Bioengineering, Faculty of Engineering, National University of Singapore, Singapore
    Prog Biophys Mol Biol 98:38-51. 2008
  3. pmc Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
    Sudhakar Jonnalagadda
    Department of Chemical and Biomolecular Engineering, National University of Singapore, 10 Kent Ridge Crescent, Singapore
    BMC Bioinformatics 9:267. 2008
  4. doi Positive association between plasma homocysteine level and chronic kidney disease
    Anoop Shankar
    Division of Epidemiology, Department of Community, Occupational, and Family Medicine, National University of Singapore, Singapore
    Kidney Blood Press Res 31:55-62. 2008
  5. ncbi Novel melanocortin 4 receptor gene mutations in severely obese children
    Yung Seng Lee
    Department of Paediatrics, National University of Singapore, and The Children s Medical Institute, National University Hospital, Singapore
    Clin Endocrinol (Oxf) 68:529-35. 2008
  6. ncbi Body mass index, waist circumference, waist-hip ratio and depressive symptoms in Chinese elderly: a population-based study
    Roger C M Ho
    Department of Psychological Medicine, National University of Singapore, Singapore
    Int J Geriatr Psychiatry 23:401-8. 2008
  7. ncbi Liposomal doxorubicin-associated acute hypersensitivity despite appropriate preventive measures
    Alexandre Chan
    Department of Pharmacy, National University of Singapore, Singapore
    J Oncol Pharm Pract 13:105-7. 2007
  8. ncbi Filter performance parameters for high-aperture focusing
    Colin J R Sheppard
    Department of Diagnostic Radiology, National University of Singapore
    Opt Lett 32:1653-5. 2007
  9. ncbi Increased vascular permeability and nitric oxide production in response to hypoxia in the pineal gland
    C Kaur
    Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Pineal Res 42:338-49. 2007
  10. ncbi Direct force measurement of bacteria adhesion on metal in aqueous media
    S Xiaoxia
    Department of Chemical and Bimolecular Engineering, National University of Singapore, 10 Kent Ridge, 119260 Singapore
    Water Sci Technol 54:17-25. 2006

Scientific Experts

Detail Information

Publications62

  1. ncbi Facile patterning of upconversion NaYF4:Yb,Er nanoparticles
    Hua Yan Si
    Department of Materials Science and Engineering, National University of Singapore, Singapore 117540, Republic of Singapore
    J Colloid Interface Sci 353:569-73. 2011
    ..The structures of NaYF(4):Yb,Er particles patterns depended on the dimension of the substrate, the concentration of the NaYF(4):Yb,Er nanoparticles and the water condensation process...
  2. doi Practical application of CellML 1.1: The integration of new mechanisms into a human ventricular myocyte model
    David Nickerson
    Division of Bioengineering, Faculty of Engineering, National University of Singapore, Singapore
    Prog Biophys Mol Biol 98:38-51. 2008
    ..By doing so, all simulations are able to be duplicated by anyone with access to a capable tool. Similarly, identical graphical representations of the numerical simulation results can be produced...
  3. pmc Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
    Sudhakar Jonnalagadda
    Department of Chemical and Biomolecular Engineering, National University of Singapore, 10 Kent Ridge Crescent, Singapore
    BMC Bioinformatics 9:267. 2008
    ..These differentially expressed genes can reveal the changes in biological process due to the change in condition which is essential to understand differences in dynamics...
  4. doi Positive association between plasma homocysteine level and chronic kidney disease
    Anoop Shankar
    Division of Epidemiology, Department of Community, Occupational, and Family Medicine, National University of Singapore, Singapore
    Kidney Blood Press Res 31:55-62. 2008
    ..However, relatively few clinical/epidemiological studies have examined this hypothesis in humans. We examined the relationship between plasma homocysteine level and CKD in a population-based study of older Australians...
  5. ncbi Novel melanocortin 4 receptor gene mutations in severely obese children
    Yung Seng Lee
    Department of Paediatrics, National University of Singapore, and The Children s Medical Institute, National University Hospital, Singapore
    Clin Endocrinol (Oxf) 68:529-35. 2008
    ..The significance of MC4R mutations in Asian obese populations has not been adequately examined. The objective of this study was to determine the role of MC4R mutations in severely obese Asian children...
  6. ncbi Body mass index, waist circumference, waist-hip ratio and depressive symptoms in Chinese elderly: a population-based study
    Roger C M Ho
    Department of Psychological Medicine, National University of Singapore, Singapore
    Int J Geriatr Psychiatry 23:401-8. 2008
    ..The use of BMI fails to account for varying proportions of muscle, fat and bone, and few studies have used other measures of central obesity, such as waist-hip ratio (WHR) and waist circumference (WC)...
  7. ncbi Liposomal doxorubicin-associated acute hypersensitivity despite appropriate preventive measures
    Alexandre Chan
    Department of Pharmacy, National University of Singapore, Singapore
    J Oncol Pharm Pract 13:105-7. 2007
    ..Further research should identify patients who are at risk of experiencing such hypersensitivity...
  8. ncbi Filter performance parameters for high-aperture focusing
    Colin J R Sheppard
    Department of Diagnostic Radiology, National University of Singapore
    Opt Lett 32:1653-5. 2007
    ..These measures can be used to investigate focusing properties of different types of focusing systems, including those with apodizers and superresolving masks...
  9. ncbi Increased vascular permeability and nitric oxide production in response to hypoxia in the pineal gland
    C Kaur
    Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Pineal Res 42:338-49. 2007
    ..Administration of exogenous melatonin may be beneficial as it reduced VEGF concentration and NO production significantly in hypoxic rats, and leakage of RhIC was concomitantly reduced...
  10. ncbi Direct force measurement of bacteria adhesion on metal in aqueous media
    S Xiaoxia
    Department of Chemical and Bimolecular Engineering, National University of Singapore, 10 Kent Ridge, 119260 Singapore
    Water Sci Technol 54:17-25. 2006
    ..The adhesion forces were also influenced by the physiological properties of the bacterium, such as the bacterial surface charges and hydrophobicity...
  11. ncbi Transversely isotropic properties of porcine liver tissue: experiments and constitutive modelling
    C Chui
    Department of Mechanical Engineering, Faculty of Engineering, National University of Singapore, Singapore, Singapore
    Med Biol Eng Comput 45:99-106. 2007
    ....
  12. ncbi Apoptosis in the pathophysiology of diabetes mellitus
    Shao Chin Lee
    National University Medical Institutes, National University of Singapore, Singapore 117597, Singapore
    Int J Biochem Cell Biol 39:497-504. 2007
    ..Here, we provide a short review on the apoptotic death circuitry in the pathogenesis of diabetes...
  13. ncbi Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats
    Yi Zhun Zhu
    Department of Pharmacology, National University of Singapore, 10 Kent Ridge Crescent, Singapore 117597
    J Appl Physiol (1985) 102:261-8. 2007
    ..PAG reduced endogenous H(2)S production after MI by inhibiting cystathionine-gamma-lyase. The results suggest that H(2)S might provide a novel approach to the treatment of MI...
  14. ncbi The effect of levonorgestrel-releasing intrauterine system use on menstrual blood loss and the hemostatic, fibrinolytic/inhibitor systems in women with menorrhagia
    S C L Koh
    Department of Obstetrics and Gynaecology, National University of Singapore, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Singapore
    J Thromb Haemost 5:133-8. 2007
    ..The levonorgestrel-releasing intrauterine system (LNG-IUS) ranks higher than medical treatments in terms of efficacy, comparable improvements in quality of life and psychological well-being...
  15. doi Pentachlorophenol dechlorination by an acidogenic sludge
    Cheok Hong Mun
    Division of Environmental Science and Engineering, National University of Singapore, Singapore 117576
    Water Res 42:3789-98. 2008
    ..Overall, acidogenic biotreatment was an effective process in reducing PCP loads prior to downstream biological treatment...
  16. doi Investigating the physiological responses of patients listening to music in the intensive care unit
    Moon Fai Chan
    Alice Lee Centre for Nursing Studies, National University of Singapore, Singapore
    J Clin Nurs 18:1250-7. 2009
    ..To determine whether definable subtypes exist within a cohort of patients listening to music with regard to their physiological patterns and to compare whether associated factors vary between subjects in groups with different profiles...
  17. pmc New insights on classification, identification, and clinical relevance of Blastocystis spp
    Kevin S W Tan
    Department of Microbiology, Laboratory of Molecular and Cellular Parasitology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore
    Clin Microbiol Rev 21:639-65. 2008
    ..This review focuses on such recent advances and also provides updates on laboratory and clinical aspects of Blastocystis spp...
  18. pmc MCL-CAw: a refinement of MCL for detecting yeast complexes from weighted PPI networks by incorporating core-attachment structure
    Sriganesh Srihari
    Department of Computer Science, National University of Singapore, Singapore
    BMC Bioinformatics 11:504. 2010
    ..However, MCL produces many noisy clusters, which either do not match known complexes or have additional proteins that reduce the accuracies of correctly predicted complexes...
  19. doi Deformation of nasal septum during nasal trauma
    Shu Jin Lee
    Division of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital, Singapore
    Laryngoscope 120:1931-9. 2010
    ..Injury to the nasal septum is commonly found in most nasal fractures. The nasal septum deforms and crumples, leading to nasal deviation and internal nasal obstruction...
  20. doi Cross-cultural application of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): performances of elderly Chinese Singaporeans
    May Li Lim
    Department of Psychological Medicine, National University of Singapore, Singapore
    Clin Neuropsychol 24:811-26. 2010
    ....
  21. doi Procedure-related myonecrosis after bare and drug-eluting stent implantation
    Chi Hang Lee
    Cardiac Department, National University Heart Center, 5 Lower Kent Ridge Road, Singapore
    Asian Cardiovasc Thorac Ann 18:272-8. 2010
    ..In this study, bare metal stents and the 4 drug-eluting stents were associated with similar low incidences of myonecrosis, myocardial infarction, and large myocardial infarction...
  22. doi Changes in brain cholesterol metabolome after excitotoxicity
    Wei Yi Ong
    Department of Anatomy, National University of Singapore, Singapore, 119260, Singapore
    Mol Neurobiol 41:299-313. 2010
    ..Together, the findings suggest that increased cholesterol and COPs after KA excitotoxicity could themselves lead to disturbed neuronal ion homeostasis, increased neurotransmitter release, and propagation of excitotoxicity...
  23. doi An S-shaped relationship between changes in appraisals and changes in emotions
    Eddie M W Tong
    Department of Psychology, National University of Singapore
    Emotion 9:821-37. 2009
    ....
  24. ncbi A novel "in-situ tulip-bud deployment" method for transcatheter closure of secundum atrial septal defect
    Swee Chye Quek
    Department of Paediatrics, National University of Singapore, Singapore and the Gleneagles Hospital, Singapore
    J Invasive Cardiol 21:623-6. 2009
    ..We devised a new technique for interventional closure of atrial septal defect (ASD) using the Amplatzer Septal Occluder (ASO), and validated this by comparing it with a cohort using the conventional method...
  25. pmc MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis
    T Narasaraju
    Infectious Diseases Program, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Kent Ridge 117597, Singapore
    Am J Respir Cell Mol Biol 42:732-43. 2010
    ....
  26. doi Ex utero harvest of hematopoietic stem cells from placenta/umbilical cord with an automated collection system
    K K Tan
    Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117576, Singapore
    IEEE Trans Biomed Eng 56:2331-4. 2009
    ..Results, in terms of mononucleated cells (MNCs) count, CD34+ cells count, as well as flow cytometry, will be furnished to verify the effectiveness of the developed system...
  27. pmc Dynamic regulation of RNA editing of ion channels and receptors in the mammalian nervous system
    Bao Zhen Tan
    Department of Physiology, Yong Loo Lin School Medicine, National University of Singapore, 117597, Singapore
    Mol Brain 2:13. 2009
    ..Here, we review the mechanisms that could regulate adenosine-to-inosine RNA editing and the impact of dysregulation in clinical conditions...
  28. doi Injury and recovery: severe amnestic syndrome following traumatic brain injury
    Simon L Collinson
    Department of Psychology, National University of Singapore, Singapore
    Brain Inj 23:71-6. 2009
    ..To illustrate the clinical course of a patient with a marked amnestic syndrome resulting from a closed head injury that had significant effects on frontal and thalamic memory structures...
  29. doi Inhibition of cough-reflex sensitivity by benzonatate and guaifenesin in acute viral cough
    Peter V Dicpinigaitis
    Albert Einstein College of Medicine and Montefiore Medical Center, 1825 Eastchester Road, Bronx, NY 10461, USA
    Respir Med 103:902-6. 2009
    ..008). The mechanism by which the combination of B+G causes a potentiation of antitussive effect remains to be elucidated. Our results suggest that B+G may be an effective therapy for acute cough due to the common cold (URI)...
  30. doi Inter-individual variation in expression: a missing link in biomarker biology?
    Peter F R Little
    University Hall, National University of Singapore, 119077 Singapore
    Trends Biotechnol 27:5-10. 2009
    ..We argue that a consideration of genetics, in conjunction with proteomic biomarker discovery projects, should improve the proportion of biomarkers that can accurately classify patients...
  31. ncbi Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration
    Jerry Chan
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, United Kingdom
    Stem Cells 24:1879-91. 2006
    ..The high degree of myogenic conversion achieved by this method has relevance for the development of therapies for muscular dystrophies...
  32. ncbi Evaluating the pharmacoeconomic effect of adding tiotropium bromide to the management of chronic obstructive pulmonary disease patients in Singapore
    Kang Hoe Lee
    Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Respir Med 100:2190-6. 2006
    ..To perform a pharmacoeconomic analysis on the treatment of chronic obstructive pulmonary disease (COPD) with the addition of tiotropium bromide...
  33. ncbi Immunocytochemistry versus molecular fingerprinting of metastases
    M Salto-Tellez
    Department of Pathology, National University of Singapore, Singapore, Republic of Singapore
    Cytopathology 14:186-90. 2003
    ..We conclude that immunocytochemical and molecular biology approaches to the diagnosis of tumours may give rise to contradictory results...
  34. ncbi What is true community-acquired urinary tract infection? Comparison of pathogens identified in urine from routine outpatient specimens and from community clinics in a prospective study
    T Y Ti
    Department of Pharmacology, Faculty of Medicine, MD2, National University of Singapore, 18 Medical Drive, 117597 Singapore
    Eur J Clin Microbiol Infect Dis 22:242-5. 2003
    ..Hence, surveys based on laboratory data alone may overestimate resistance rates, leading to misinformed choices being made when treatment is empirical...
  35. ncbi Can social marketing be applied to leprosy programmes?
    Mee Lian Wong
    Department of Community, Occupational and Family Medicine MD 3, Faculty of Medicine, National University of Singapore, Lower Kent Ridge Road, Singapore 119260
    Lepr Rev 73:308-18. 2002
    ..The paper concludes with a discussion of the opportunities for using social marketing principles to enhance the success of current leprosy community heath education programmes and leprosy treatment services...
  36. pmc Review of recent epidemiological studies on paternal occupations and birth defects
    S E Chia
    Department of Community, Occupational and Family Medicine, MD3, Faculty of Medicine, National University of Singapore, 16 Medical Drive, Singapore 117597, Republic of Singapore
    Occup Environ Med 59:149-55. 2002
    ..Future studies could be focused on these specific, rather than general, occupational groups so that causative agents may be confirmed and thus enable appropriate preventive measures to be taken...
  37. ncbi Prediction of potential toxicity and side effect protein targets of a small molecule by a ligand-protein inverse docking approach
    Y Z Chen
    Department of Computational Science, National University of Singapore
    J Mol Graph Model 20:199-218. 2001
    ..There are additional 30 predicted targets yet to be validated experimentally. Application of this computer approach can potentially facilitate the prediction of toxicity and side effect of a drug or drug lead...
  38. ncbi Optimization of stacked half-hitch knots for arthroscopic surgery
    K C Chan
    Department of Orthopaedic Surgery, National University Hospital, National University of Singapore, Republic of Singapore
    Arthroscopy 17:752-9. 2001
    ..This study was conducted to determine the optimal configuration of stacked half-hitch knots that would give the maximum knot-holding capacity (KHC). Type of Study: Mechanical testing study...
  39. ncbi Chinese proprietary medicine in Singapore: regulatory control of toxic heavy metals and undeclared drugs
    H L Koh
    Department of Pharmacy, National University of Singapore
    Drug Saf 23:351-62. 2000
    ....
  40. ncbi Effects of aging on repair of resin-modified glass-ionomer cements
    A U Yap
    Faculty of Dentistry, National University of Singapore, Singapore
    J Oral Rehabil 27:422-7. 2000
    ..There appears to be a general decrease in repair bond strengths for all treatment groups after 3 months storage. The clinical repair of resin-modified glass-ionomer cements after this period of time is therefore not recommended...
  41. ncbi Effects of inhibitors of guanine nucleotide synthesis on membrane potential and cytosolic free Ca2+ levels in insulin-secreting cells
    G D Li
    Cardiovascular Research Institute, National University Medical Institutes, National University of Singapore, Singapore
    Biochem Pharmacol 59:545-56. 2000
    ..In addition, GN depletion appeared to be able to reduce stimulated insulin secretion by a mechanism largely independent of the changes of ion fluxes observed above...
  42. ncbi Surface laser scanning of the cleft palate deformity--validation of the method
    K W Foong
    Department of Preventive Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
    Ann Acad Med Singapore 28:642-9. 1999
    ..05). While landmarks could be localised repeatedly without the aid of a visual marker, landmarks well defined by a clearly visible visual cue on the three-dimensional image were more reliable...
  43. ncbi Evacuation interval after vaginal misoprostol for preabortion cervical priming: a randomized trial
    K Singh
    Department of Obstetrics and Gynaecology, National University Hospital, Singapore
    Obstet Gynecol 94:431-4. 1999
    ..To determine the optimal interval for evacuation after preabortion cervical priming with vaginal misoprostol...
  44. ncbi Pharmacist-operated drug information centres in Singapore
    L Y Lim
    Department of Pharmacy, National University of Singapore, Singapore
    J Clin Pharm Ther 24:33-42. 1999
    ..Here we evaluate the four pharmacist-operated DICs in Singapore and compare them with published information on DICs located in Australia, the U.K. and the U.S., and with established guidelines for quality assurance of DICs...
  45. ncbi Symptomatic gastro-oesophageal reflux in pregnancy: a prospective study among Singaporean women
    K Y Ho
    Department of Medicine, National University of Singapore, Singapore
    J Gastroenterol Hepatol 13:1020-6. 1998
    ..Reflux-type symptoms were related to nausea and vomiting, both in frequency and time pattern of onset and disappearance of symptoms. The association suggested either a common mechanism or a cause and effect relationship...
  46. ncbi Flexible chitin films as potential wound-dressing materials: wound model studies
    Nealda Leila Binte Muhammad Yusof
    Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543
    J Biomed Mater Res A 66:224-32. 2003
    ..Based on histological examination, wound sites dressed with the chitin films stabilized and healed faster, and appeared stronger than those dressed with Opsite trade mark and gauze dressings after 7 days of healing...
  47. ncbi beta-Phenylethyl isothiocyanate-mediated apoptosis in hepatoma HepG2 cells
    P Rose
    Department of Community, Occupational and Family Medicine, MD3, National University of Singapore, 16 Medical Drive, 117597 Singapore
    Cell Mol Life Sci 60:1489-503. 2003
    ..Taken together, these results suggest that PEITC potently induces apoptosis and cell cycle arrest in HepG2 cells and that the generation of reactive oxygen species appears to be a secondary effect...
  48. ncbi Identification and molecular phylogeny of Epulorhiza isolates from tropical orchids
    Ming Ma
    Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Kent Ridge, 117543 Singapore
    Mycol Res 107:1041-9. 2003
    ..No matching sequences have been found in the GenBank database for the ITS region of E. repens and E. calendulina-like Rhizoctonia...
  49. ncbi Partial urethral obstruction enhances NADPH-diaphorase activity in the monkey (Macaca fascicularis) bladder: light and electron microscopic studies
    S D Kumar
    Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Histol Histopathol 21:383-91. 2006
    ..However, it warrants further investigation to understand the mechanism of neuronal cell death after partial urethral obstruction...
  50. ncbi A hypothesis matrix for studying biomechanical factors associated with the initiation and progression of posttraumatic osteoarthritis
    Ashvin Thambyah
    Department of Orthopaedic Surgery, National University of Singapore, Singapore 119074, Singapore
    Med Hypotheses 64:1157-61. 2005
    ..The biomechanical events are therefore used to predict the risk of mechanically driven OA and the rapidity in which it progresses in relation to joint loading...
  51. ncbi Radiolabelling of egg meals for gastric emptying studies: a comparison of 99mTc sulfur and 99mTc stannous colloids
    Borys Shuter
    Department of Diagnostic Imaging, National University Hospital, Singapore
    Nucl Med Commun 26:369-74. 2005
    ....
  52. ncbi Development of a flow cytometry based method for rapid and sensitive detection of a novel marine fish iridovirus in cell culture
    Qi Wei Qin
    State Key Laboratory for Biocontrol, College of Life Science, Zhongshan University, 135 West Xingang Road, Guangzhou 510275, PR China
    J Virol Methods 125:49-54. 2005
    ..The maximum level of infection was obtained at 72 h. The efficiency and reliability of the FCM procedure were compared with those of the standard methods of immunofluorescence microscopy and PCR...
  53. ncbi Geometrical interpretation and architecture selection of MLP
    Cheng Xiang
    Department of Electrical and Computer Engineering, National University of Singapore, Singapore 119260
    IEEE Trans Neural Netw 16:84-96. 2005
    ..e., the number of the hidden neurons and the hidden layers, are proposed based upon this interpretation and the controversial issue of whether four-layered MLP is superior to the three-layered MLP is also carefully examined...
  54. ncbi Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia
    S Thameem Dheen
    Department of Anatomy, Molecular Neurobiology Laboratory, Faculty of Medicine, National University of Singapore, Singapore
    Glia 50:21-31. 2005
    ..These results suggest that RA may inhibit the neurotoxic effect of activated microglia by suppressing the production of inflammatory cytokines and cytotoxic molecules...
  55. ncbi Electron-acoustic and surface electron beam induced voltage signal formation in scanning electron microscopy analysis of semiconducting samples
    W K Wong
    Department of Electrical and Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117576, Singapore
    Ultramicroscopy 101:183-95. 2004
    ....
  56. ncbi Remote homolog detection using local sequence-structure correlations
    Yuna Hou
    School of Computing, National University of Singapore, Singapore
    Proteins 57:518-30. 2004
    ..Tests using the Structural Classification of Proteins (SCOP) 1.53 data set show that the SVM-HMMSTR gives a significant improvement over several current methods...
  57. ncbi Antisense knockdown of sphingosine kinase 1 in human macrophages inhibits C5a receptor-dependent signal transduction, Ca2+ signals, enzyme release, cytokine production, and chemotaxis
    Alirio J Melendez
    Department of Physiology, National University of Singapore, Singapore
    J Immunol 173:1596-603. 2004
    ....
  58. ncbi The impact of diabetes mellitus on the prognostic value of a normal dobutamine stress echocardiogram in patients with intermediate to high cardiovascular risk
    A F Low
    Cardiac Department, National University of Singapore, National University Hospital, Singapore
    Singapore Med J 45:161-5. 2004
    ..The impact of diabetes mellitus, recently recognised as a cardiovascular risk-equivalent, has not been previously evaluated. This study aims to determine the prognostic value of a normal DSE in these patients...
  59. ncbi Neuroprotective role of aminoguanidine in behavioral changes after blast injury
    Shabbir M Moochhala
    Defence Medical Research Institute, Defence Science and Technology Agency, National University of Singapore, Singapore
    J Trauma 56:393-403. 2004
    ..The present study investigated the neuroprotective role of aminoguanidine, a known inducible nitric oxide synthase inhibitor, in both behavioral and morphologic changes in rats subjected to nonpenetrative blast injury...
  60. ncbi Influence of storage conditions and type of plasticizers on ethylcellulose and acrylate films formed from aqueous dispersions
    Paul W S Heng
    Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore
    J Pharm Pharm Sci 6:334-44. 2003
    ..To investigate the influence of storage conditions and types of plasticizers on the properties and stability of ethylcellulose and polymethacrylate films and to elucidate the mechanism for the changes observed...
  61. ncbi Mineralized bone loss in partially edentulous trabeculae of ovariectomized rabbit mandibles
    T Cao
    Faculty of Dentistry, National University of Singapore, National University Hospital, 119074
    J Periodontal Res 39:37-41. 2004
    ..The purpose of this study was to evaluate trabeculae changes in partially edentulous bone in ovariectomized rabbits...
  62. ncbi Vasorelaxation of rat thoracic aorta caused by 14-deoxyandrographolide
    C Y Zhang
    Department of Pharmacology, Faculty of Medicine, National University of Singapore, Singapore
    Clin Exp Pharmacol Physiol 25:424-9. 1998
    ....