Annemiek B van Spriel

Summary

Affiliation: Shahid Beheshti University

Publications

  1. doi request reprint Tetraspanins in the humoral immune response
    Annemiek B van Spriel
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, 278 TIL, Radboud University Nijmegen Medical Centre, Post Box 9101, 6500HB, Nijmegen, The Netherlands
    Biochem Soc Trans 39:512-7. 2011
  2. ncbi request reprint Novel immunotherapeutic strategies for invasive fungal disease
    A B van Spriel
    Leukocyte Membrane Protein Laboratory, Austin Research Institute, Kronheimer Building, A and RMC, Studley Road, Heidelberg, VIC 3084, Australia
    Curr Drug Targets Cardiovasc Haematol Disord 3:209-17. 2003
  3. doi request reprint The role of tetraspanins in the pathogenesis of infectious diseases
    Annemiek B van Spriel
    Department of Tumor Immunology TIL 278, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands
    Microbes Infect 12:106-12. 2010
  4. doi request reprint Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC
    Kuo Ching Sheng
    The Burnet Institute of Medical Research and Public Health, A and RMC, Heidelberg, Australia
    Eur J Immunol 39:50-5. 2009
  5. pmc The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology
    Angelique L Rops
    Nephrology Research Laboratory and Department of Nephrology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Pathol 176:2188-97. 2010
  6. pmc The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity
    Annemiek B van Spriel
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands
    PLoS Pathog 5:e1000338. 2009
  7. pmc The Y238X stop codon polymorphism in the human β-glucan receptor dectin-1 and susceptibility to invasive aspergillosis
    Louis Y A Chai
    Department of Medicine, Radboud University Nijmegen Medical Centre, The Netherlands
    J Infect Dis 203:736-43. 2011
  8. ncbi request reprint Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production
    Friederike Meyer-Wentrup
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands
    J Immunol 178:154-62. 2007
  9. pmc Human dectin-1 deficiency and mucocutaneous fungal infections
    Bart Ferwerda
    Department of Internal Medicine and the Nijmegen Institute for Infection, Inflammation, and Immunity, Radboud University Nijmegen, Nijmegen, The Netherlands
    N Engl J Med 361:1760-7. 2009
  10. doi request reprint Vitamin D controls murine and human plasmacytoid dendritic cell function
    Nina Karthaus
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands
    J Invest Dermatol 134:1255-64. 2014

Collaborators

Detail Information

Publications24

  1. doi request reprint Tetraspanins in the humoral immune response
    Annemiek B van Spriel
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, 278 TIL, Radboud University Nijmegen Medical Centre, Post Box 9101, 6500HB, Nijmegen, The Netherlands
    Biochem Soc Trans 39:512-7. 2011
    ..The present review focuses on tetraspanins expressed by B-lymphocytes and discusses novel insights into the function of tetraspanins in the humoral immune response...
  2. ncbi request reprint Novel immunotherapeutic strategies for invasive fungal disease
    A B van Spriel
    Leukocyte Membrane Protein Laboratory, Austin Research Institute, Kronheimer Building, A and RMC, Studley Road, Heidelberg, VIC 3084, Australia
    Curr Drug Targets Cardiovasc Haematol Disord 3:209-17. 2003
    ..Controlled comparative clinical research is needed to evaluate the efficacy of novel immunotherapies, which provide prospects for the future management of invasive fungal disease...
  3. doi request reprint The role of tetraspanins in the pathogenesis of infectious diseases
    Annemiek B van Spriel
    Department of Tumor Immunology TIL 278, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands
    Microbes Infect 12:106-12. 2010
    ..In this review, we will focus on tetraspanins expressed in the immune system and the role they play in the defense to viral, bacterial, parasitic and fungal infections...
  4. doi request reprint Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC
    Kuo Ching Sheng
    The Burnet Institute of Medical Research and Public Health, A and RMC, Heidelberg, Australia
    Eur J Immunol 39:50-5. 2009
    ..The implications of these results on the model suggesting that tetraspanins promote MHC multimerisation are discussed...
  5. pmc The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology
    Angelique L Rops
    Nephrology Research Laboratory and Department of Nephrology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Pathol 176:2188-97. 2010
    ..Therefore, CD37 may protect against the development of IgA nephropathy...
  6. pmc The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity
    Annemiek B van Spriel
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands
    PLoS Pathog 5:e1000338. 2009
    ..Taken together, tetraspanin protein CD37 inhibits IgA responses and regulates the anti-fungal immune response...
  7. pmc The Y238X stop codon polymorphism in the human β-glucan receptor dectin-1 and susceptibility to invasive aspergillosis
    Louis Y A Chai
    Department of Medicine, Radboud University Nijmegen Medical Centre, The Netherlands
    J Infect Dis 203:736-43. 2011
    ..We investigated whether defective Dectin-1 receptor function, because of the early stop codon polymorphism Y238X, enhances susceptibility to invasive aspergillosis (IA) in at-risk patients...
  8. ncbi request reprint Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production
    Friederike Meyer-Wentrup
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands
    J Immunol 178:154-62. 2007
    ..Taken together, these findings show that tetraspanin CD37 is important for dectin-1 stabilization in APC membranes and controls dectin-1-mediated IL-6 production...
  9. pmc Human dectin-1 deficiency and mucocutaneous fungal infections
    Bart Ferwerda
    Department of Internal Medicine and the Nijmegen Institute for Infection, Inflammation, and Immunity, Radboud University Nijmegen, Nijmegen, The Netherlands
    N Engl J Med 361:1760-7. 2009
    ....
  10. doi request reprint Vitamin D controls murine and human plasmacytoid dendritic cell function
    Nina Karthaus
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands
    J Invest Dermatol 134:1255-64. 2014
    ..This study demonstrates that VitD signaling can act as a natural inhibitory mechanism on both cDCs and pDCs, which may instigate the development of VitD-based therapeutic applications for psoriasis and other inflammatory skin diseases. ..
  11. doi request reprint The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival
    Annemiek B van Spriel
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen 6525 GA, The Netherlands
    Sci Signal 5:ra82. 2012
    ..CD37 was required for the mobility and clustering of α(4)β(1) integrins in the plasma membrane, thus regulating the membrane distribution of α(4)β(1) integrin necessary for activation of the Akt survival pathway in the immune system...
  12. pmc Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs
    Charlotte M de Winde
    Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein Zuid 26, 6525 GA, Nijmegen, The Netherlands
    Histochem Cell Biol 144:133-46. 2015
    ..This study provides a solid basis for better insight into the function of tetraspanins in the human immune response. ..
  13. doi request reprint Tetraspanins in the immune response against cancer
    Sharon Veenbergen
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB, Nijmegen, The Netherlands
    Immunol Lett 138:129-36. 2011
    ..In this review, we discuss novel insights into tetraspanin function in immune cells, and describe how this may control anti-tumor immunity...
  14. doi request reprint Fungal pattern-recognition receptors and tetraspanins: partners on antigen-presenting cells
    Carl G Figdor
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Trends Immunol 31:91-6. 2010
    ..We postulate that upon fungal binding tetraspanins modulate the function of F-PRRs by their recruitment into tetraspanin microdomains, leading to immune activation or tolerance...
  15. doi request reprint Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients
    Theo S Plantinga
    Departments of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Clin Infect Dis 49:724-32. 2009
    ....
  16. doi request reprint Microdomains in the membrane landscape shape antigen-presenting cell function
    Malou Zuidscherwoude
    1 Nijmegen Centre for Molecular Life Sciences 278 TIL, Radboud University Medical Centre, Geert Grooteplein 28, 6525GA, Nijmegen, The Netherlands
    J Leukoc Biol 95:251-63. 2014
    ....
  17. doi request reprint Nuclear receptor expression patterns in murine plasmacytoid and conventional dendritic cells
    Nina Karthaus
    Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mol Immunol 55:409-17. 2013
    ..Expression levels, however, differed between the two subsets, especially upon maturation of DCs. These data imply that NR ligands do impact pDC function and that their activity might be regulated in a DC-specific manner...
  18. doi request reprint Binding and uptake of Candida albicans by human monocyte-derived dendritic cells
    Annemiek B van Spriel
    Department of Tumor Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Methods Mol Biol 845:319-31. 2012
    ..albicans using fluorescently labeled antibodies and confocal microscopy. Both methods can be applied to determine binding and uptake of other pathogens by different types of immune cells...
  19. pmc The tetraspanin web revisited by super-resolution microscopy
    Malou Zuidscherwoude
    Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
    Sci Rep 5:12201. 2015
    ..This study increases the molecular understanding of TEMs at the nanoscale level which is essential for comprehending tetraspanin function in cell biology. ..
  20. doi request reprint Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration
    Anoek van Rijn
    Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands
    J Immunol 196:459-68. 2016
    ..This study demonstrates that Sema7A controls the assembly of actin-based protrusions that drive DC migration in response to CCL21. ..
  21. doi request reprint Interleukin-21 receptor deficiency increases the initial toll-like receptor 2 response but protects against joint pathology by reducing Th1 and Th17 cells during streptococcal cell wall arthritis
    Renoud J Marijnissen
    Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Arthritis Rheumatol 66:886-95. 2014
    ..The cytokine interleukin-21 (IL-21) can have both proinflammatory and immunosuppressive effects. The purpose of this study was to investigate the potential dual role of IL-21 in experimental arthritis in relation to Th17 cells...
  22. doi request reprint Dendritic cell science: more than 40 years of history
    Annemiek B van Spriel
    Nijmegen Centre for Molecular Life Sciences, Geert Grooteplein 28, Nijmegen, The Netherlands
    J Leukoc Biol 93:33-8. 2013
    ..Beutler and Jules A. Hoffmann (for their discoveries in innate immune recognition) and Ralph M. Steinman (for his discovery of the DC)...
  23. ncbi request reprint A regulatory role for CD37 in T cell proliferation
    Annemiek B van Spriel
    Leukocyte Membrane Protein Laboratory, Austin Research Institute, Victoria, Australia
    J Immunol 172:2953-61. 2004
    ..In the presence of CD28 costimulation, CD37 engagement still significantly reduced proliferation. Taken together, these results demonstrate a regulatory role for CD37 in T cell proliferation by influencing early events of TCR signaling...
  24. ncbi request reprint Neutrophil Fc gamma RI as target for immunotherapy of invasive candidiasis
    A B van Spriel
    Immunotherapy Laboratory, Medarex Europe, and Genmab, University Medical Center, Utrecht, The Netherlands
    J Immunol 166:7019-22. 2001
    ..These findings document the capacity of FcgammaRI to initiate potent anti-C. albicans immunity and support the development of FcgammaRI-directed immunotherapy of invasive fungal disease...