Amanda M Schrand

Summary

Publications

  1. doi request reprint Assessment of cytotoxicity of carbon nanoparticles using 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) cell viability assay
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright Patterson Air Force Base, OH, USA
    Methods Mol Biol 906:395-402. 2012
  2. ncbi request reprint Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique
    Richard C Murdock
    Applied Biotechnology Branch, Human Effectiveness Directorate Air Force Research Laboratory HEPB, Wright Patterson Air Force Board, Ohio 45433, USA
    Toxicol Sci 101:239-53. 2008
  3. doi request reprint Toxicity testing of nanomaterials
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright Patterson AFB, Ohio, USA
    Adv Exp Med Biol 745:58-75. 2012
  4. doi request reprint Surface charge of gold nanoparticles mediates mechanism of toxicity
    Nicole M Schaeublin
    Applied Biotechnology Branch, Human Effectiveness Directorate, 711 Human Performance Wing, Air Force Research Laboratory, Area B, R Street, Bldg 837, Wright Patterson AFB, OH 45433 5707, USA
    Nanoscale 3:410-20. 2011
  5. doi request reprint Metal-based nanoparticles and their toxicity assessment
    Amanda M Schrand
    Wright Patterson Air Force Base, Dayton, OH 45433, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 2:544-68. 2010
  6. doi request reprint Preparation of cells for assessing ultrastructural localization of nanoparticles with transmission electron microscopy
    Amanda M Schrand
    AFRL 711 HPW RHPB, Wright Patterson Air Force Base, Dayton, Ohio, USA
    Nat Protoc 5:744-57. 2010
  7. ncbi request reprint Cellular interaction of different forms of aluminum nanoparticles in rat alveolar macrophages
    Andrew J Wagner
    Air Force Institute of Technology, Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force, Research Laboratory, Wright Patterson AFB, Ohio, USA
    J Phys Chem B 111:7353-9. 2007
  8. ncbi request reprint Can silver nanoparticles be useful as potential biological labels?
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright Patterson AFB, OH, 45433 5707, USA Department of Chemical and Materials Engineering, University of Dayton, 300 College Park, Dayton, OH 45469 0160, USA
    Nanotechnology 19:235104. 2008
  9. doi request reprint Fundamental examination of nanoparticle heating kinetics upon near infrared (NIR) irradiation
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness and Protection Directorate, 711th Human Performance Wing, Wright Patterson Air Force Base, Ohio 45433 5707, USA
    ACS Appl Mater Interfaces 3:3971-80. 2011
  10. doi request reprint Temporal and mechanistic tracking of cellular uptake dynamics with novel surface fluorophore-bound nanodiamonds
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, AFRL RHPB, 2729 R Street, Bldg 837, Wright Patterson AFB, OH 45433 5707, USA
    Nanoscale 3:435-45. 2011

Collaborators

  • Liming Dai
  • Saber M Hussain
  • John J Schlager
  • Richard C Murdock
  • Nicole M Schaeublin
  • Laura K Braydich-Stolle
  • Janice L Speshock
  • Andrew J Wagner
  • Jeanne E Skebo
  • Jim Hutchison
  • John M Miller
  • Laura Braydich-Stolle
  • Christin M Grabinski
  • Charles A Bleckmann
  • Helen M Duhart
  • Syed F Ali
  • Amanda K Javorina

Detail Information

Publications13

  1. doi request reprint Assessment of cytotoxicity of carbon nanoparticles using 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) cell viability assay
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright Patterson Air Force Base, OH, USA
    Methods Mol Biol 906:395-402. 2012
    ....
  2. ncbi request reprint Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique
    Richard C Murdock
    Applied Biotechnology Branch, Human Effectiveness Directorate Air Force Research Laboratory HEPB, Wright Patterson Air Force Board, Ohio 45433, USA
    Toxicol Sci 101:239-53. 2008
    ..It was also observed that sonication slightly reduces agglomeration and has minimal effect on particle surface charge. Finally, the stock solution experienced significant changes in particle agglomeration and surface charge over time...
  3. doi request reprint Toxicity testing of nanomaterials
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright Patterson AFB, Ohio, USA
    Adv Exp Med Biol 745:58-75. 2012
    ..Further investigation into the characteristics, uptake and mechanisms of nanomaterial toxicity will continue to elucidate this fascinating and rapidly growing area of science...
  4. doi request reprint Surface charge of gold nanoparticles mediates mechanism of toxicity
    Nicole M Schaeublin
    Applied Biotechnology Branch, Human Effectiveness Directorate, 711 Human Performance Wing, Air Force Research Laboratory, Area B, R Street, Bldg 837, Wright Patterson AFB, OH 45433 5707, USA
    Nanoscale 3:410-20. 2011
    ..In conclusion, these results indicate that surface charge is a major determinant of how Au NPs impact cellular processes, with the charged NPs inducing cell death through apoptosis and neutral NPs leading to necrosis...
  5. doi request reprint Metal-based nanoparticles and their toxicity assessment
    Amanda M Schrand
    Wright Patterson Air Force Base, Dayton, OH 45433, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 2:544-68. 2010
    ..As a result, there are many challenges to overcome before we can determine if the benefits outweigh the risks associated with NPs...
  6. doi request reprint Preparation of cells for assessing ultrastructural localization of nanoparticles with transmission electron microscopy
    Amanda M Schrand
    AFRL 711 HPW RHPB, Wright Patterson Air Force Base, Dayton, Ohio, USA
    Nat Protoc 5:744-57. 2010
    ..This protocol takes approximately 1 week...
  7. ncbi request reprint Cellular interaction of different forms of aluminum nanoparticles in rat alveolar macrophages
    Andrew J Wagner
    Air Force Institute of Technology, Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force, Research Laboratory, Wright Patterson AFB, Ohio, USA
    J Phys Chem B 111:7353-9. 2007
    ..In summary, these results show that Al-NP exhibit greater toxicity and more significantly diminish the phagocytotic ability of macrophages after 24 h of exposure when compared to Al2O3-NP...
  8. ncbi request reprint Can silver nanoparticles be useful as potential biological labels?
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright Patterson AFB, OH, 45433 5707, USA Department of Chemical and Materials Engineering, University of Dayton, 300 College Park, Dayton, OH 45469 0160, USA
    Nanotechnology 19:235104. 2008
    ..Therefore, the use of Ag nanoparticles as potential biological labels, even if the surface is chemically modified with a biocompatible material, should be approached with caution...
  9. doi request reprint Fundamental examination of nanoparticle heating kinetics upon near infrared (NIR) irradiation
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness and Protection Directorate, 711th Human Performance Wing, Wright Patterson Air Force Base, Ohio 45433 5707, USA
    ACS Appl Mater Interfaces 3:3971-80. 2011
    ..Therefore, this study reveals the differential heating kinetics of NPs excited with NIR with implications in the development of novel NIR-NP-based systems...
  10. doi request reprint Temporal and mechanistic tracking of cellular uptake dynamics with novel surface fluorophore-bound nanodiamonds
    Amanda M Schrand
    Applied Biotechnology Branch, Human Effectiveness Directorate, AFRL RHPB, 2729 R Street, Bldg 837, Wright Patterson AFB, OH 45433 5707, USA
    Nanoscale 3:435-45. 2011
    ....
  11. pmc Interaction of silver nanoparticles with Tacaribe virus
    Janice L Speshock
    Applied Biotechnology Branch, Human Effectiveness Directorate, 711th Human Performance Wing, U, S, Air Force Research Laboratory, 2729 R Street, Wright Patterson Air Force Base, OH, 45433 5707, USA
    J Nanobiotechnology 8:19. 2010
    ..abstract:..
  12. ncbi request reprint Assessment of metal nanoparticle agglomeration, uptake, and interaction using high-illuminating system
    Jeanne E Skebo
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory HEPB, Wright Patterson Air Force Base, Ohio 45433 5707, USA
    Int J Toxicol 26:135-41. 2007
    ..Additionally, an example application of nanoparticle labeling onto the surface and neurite extensions of murine neuroblastoma cells (N2A) is presented as a potential imaging tool...
  13. ncbi request reprint The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion
    Saber M Hussain
    Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force Research Laboratory, Wright Patterson AFB, Ohio 45431, USA
    Toxicol Sci 92:456-63. 2006
    ....