Anna Rosell

Summary

Publications

  1. pmc Interleukin-1beta augments angiogenic responses of murine endothelial progenitor cells in vitro
    Anna Rosell
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Cereb Blood Flow Metab 29:933-43. 2009
  2. doi request reprint Multiphasic roles for matrix metalloproteinases after stroke
    Anna Rosell
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Pharmacol 8:82-9. 2008
  3. pmc Neuroprotective effects of overexpressing tissue inhibitor of metalloproteinase TIMP-1
    Emiri Tejima
    Program in Neuroscience, Harvard Medical School, Charlestown, Massachusetts, USA
    J Neurotrauma 26:1935-41. 2009
  4. pmc Extension of the thrombolytic time window with minocycline in experimental stroke
    Yoshihiro Murata
    Neuroprotection Res Lab, Charlestown, MA 02129, USA
    Stroke 39:3372-7. 2008
  5. pmc Neuregulin-1 signaling in brain endothelial cells
    Josephine Lok
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    J Cereb Blood Flow Metab 29:39-43. 2009
  6. pmc Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats
    Kyung Pil Park
    Neuroprotection Research Laboratory, MGH East 149 2401 Charlestown, MA 02129, USA
    Stroke 40:2836-42. 2009
  7. ncbi request reprint Targeting extracellular matrix proteolysis for hemorrhagic complications of tPA stroke therapy
    Xiaoying Wang
    Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    CNS Neurol Disord Drug Targets 7:235-42. 2008
  8. ncbi request reprint Astrocytic induction of matrix metalloproteinase-9 and edema in brain hemorrhage
    Emiri Tejima
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, and Program in Neuroscience, Harvard Medical School, Boston, MA, USA
    J Cereb Blood Flow Metab 27:460-8. 2007
  9. doi request reprint Etiologic diagnosis of ischemic stroke subtypes with plasma biomarkers
    Joan Montaner
    Neurovascular Research Laboratory, Neurovascular Unit, Neurology Department, Vall d Hebron Hospital, Barcelona, Spain
    Stroke 39:2280-7. 2008
  10. doi request reprint Fas system activation in perihematomal areas after spontaneous intracerebral hemorrhage
    Pilar Delgado
    Neurovascular Research Laboratory Hospital Vall d Hebron, Passeig Vall d Hebron 119 129, 08035 Barcelona, Spain
    Stroke 39:1730-4. 2008

Collaborators

Detail Information

Publications15

  1. pmc Interleukin-1beta augments angiogenic responses of murine endothelial progenitor cells in vitro
    Anna Rosell
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Cereb Blood Flow Metab 29:933-43. 2009
    ..Further studies are warranted to assess how interactions between proinflammatory environments and EPC responses may be leveraged to enhance therapeutic angiogenesis...
  2. doi request reprint Multiphasic roles for matrix metalloproteinases after stroke
    Anna Rosell
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Pharmacol 8:82-9. 2008
    ....
  3. pmc Neuroprotective effects of overexpressing tissue inhibitor of metalloproteinase TIMP-1
    Emiri Tejima
    Program in Neuroscience, Harvard Medical School, Charlestown, Massachusetts, USA
    J Neurotrauma 26:1935-41. 2009
    ..Taken together, these cell culture and in vivo data provide initial proof-of-principle that TIMP-1 is neuroprotective against traumatic and ischemic brain injury in mice...
  4. pmc Extension of the thrombolytic time window with minocycline in experimental stroke
    Yoshihiro Murata
    Neuroprotection Res Lab, Charlestown, MA 02129, USA
    Stroke 39:3372-7. 2008
    ..In this study, we ask whether minocycline can prevent tPA-associated cerebral hemorrhage and extend the reperfusion window in an experimental stroke model in rats...
  5. pmc Neuregulin-1 signaling in brain endothelial cells
    Josephine Lok
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    J Cereb Blood Flow Metab 29:39-43. 2009
    ..These data suggest that NRG1 signaling is functional and cytoprotective in BMECs...
  6. pmc Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats
    Kyung Pil Park
    Neuroprotection Research Laboratory, MGH East 149 2401 Charlestown, MA 02129, USA
    Stroke 40:2836-42. 2009
    ..Here, we examined the temporal profiles of MMP-9 in blood and brain using a rat model of acute focal cerebral ischemia...
  7. ncbi request reprint Targeting extracellular matrix proteolysis for hemorrhagic complications of tPA stroke therapy
    Xiaoying Wang
    Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    CNS Neurol Disord Drug Targets 7:235-42. 2008
    ..The data strongly suggest that targeting the extracellular matrix proteolytic imbalance within the neurovascular unit may provide new approaches for improving the safety and efficacy of thrombolytic reperfusion therapy of stroke...
  8. ncbi request reprint Astrocytic induction of matrix metalloproteinase-9 and edema in brain hemorrhage
    Emiri Tejima
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, and Program in Neuroscience, Harvard Medical School, Boston, MA, USA
    J Cereb Blood Flow Metab 27:460-8. 2007
    ....
  9. doi request reprint Etiologic diagnosis of ischemic stroke subtypes with plasma biomarkers
    Joan Montaner
    Neurovascular Research Laboratory, Neurovascular Unit, Neurology Department, Vall d Hebron Hospital, Barcelona, Spain
    Stroke 39:2280-7. 2008
    ..Because there is no biologic marker offering precise information about stroke etiology, many patients receive a diagnosis of undetermined stroke even after all available diagnostic tests are done, precluding correct treatment...
  10. doi request reprint Fas system activation in perihematomal areas after spontaneous intracerebral hemorrhage
    Pilar Delgado
    Neurovascular Research Laboratory Hospital Vall d Hebron, Passeig Vall d Hebron 119 129, 08035 Barcelona, Spain
    Stroke 39:1730-4. 2008
    ....
  11. doi request reprint MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke
    Anna Rosell
    Neurovascular Research Laboratory, Neurovascular Unit, Department of Neurology, Universitat Autonoma de Barcelona, Institut de Recerca, Hospital Vall d Hebron, Barcelona, Spain
    Stroke 39:1121-6. 2008
    ..Our aim was to investigate MMP-2 and MMP-9 in the ischemic brain and its relation with blood-brain barrier breakdown after hemorrhagic transformation in human stroke...
  12. ncbi request reprint Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke
    Anna Rosell
    Department of Neurology, Vall d Hebron University Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain
    Stroke 37:1399-406. 2006
    ..We aimed to investigate MMP-2 (gelatinase A) and MMP-9 (gelatinase B) in brain parenchyma in both ischemic and hemorrhagic strokes...
  13. ncbi request reprint Poststroke C-reactive protein is a powerful prognostic tool among candidates for thrombolysis
    Joan Montaner
    Departament de Medicina Interna, Vall d Hebron Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain
    Stroke 37:1205-10. 2006
    ..We sought to investigate whether CRP measured before tissue plasminogen activator (tPA) treatments may add prognostic information to guide stroke thrombolysis...
  14. ncbi request reprint A matrix metalloproteinase protein array reveals a strong relation between MMP-9 and MMP-13 with diffusion-weighted image lesion increase in human stroke
    Anna Rosell
    Neurology Department, Universitat Autonoma de Barcelona, Hospital Vall d Hebron, Barcelona, Spain
    Stroke 36:1415-20. 2005
    ..In the present study we use an MMP array to investigate the blood levels of several MMPs in stroke patients and its relation with brain tissue damage and neurological outcome...
  15. ncbi request reprint Angiogenesis in symptomatic intracranial atherosclerosis: predominance of the inhibitor endostatin is related to a greater extent and risk of recurrence
    Juan F Arenillas
    Neurovascular Unit and Neurovascular Research Laboratory, Department of Neurology, Vall d Hebron Hospital, Universitat Autonoma de Barcelona, Passeig Vall d Hebron 119 129, 08035 Barcelona, Spain
    Stroke 36:92-7. 2005
    ..We aimed to investigate the relationship between the pro-angiogenic vascular endothelial growth factor (VEGF) and the anti-angiogenic endostatin, and the extent and risk of recurrence of symptomatic intracranial atherosclerosis...