Cornel Iancu

Summary

Affiliation: Iuliu Hatieganu University of Medicine and Pharmacy
Country: Romania

Publications

  1. doi Surface plasmon resonance-induced photoactivation of gold nanoparticles as mitochondria-targeted therapeutic agents for pancreatic cancer
    Lucian Mocan
    Iuliu Hatieganu University of Medicine and Pharmacy, Regional Institute of Gastroenterology and Hepatology, Department of Nanomedicine, Croitorilor Street, Cluj Napoca, Romania, 40264 439696 40264 439696
    Expert Opin Ther Targets 17:1383-93. 2013
  2. pmc Enhanced laser thermal ablation for the in vitro treatment of liver cancer by specific delivery of multiwalled carbon nanotubes functionalized with human serum albumin
    Cornel Iancu
    Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Third Surgery Clinic, Cluj Napoca, Romania
    Int J Nanomedicine 6:129-41. 2011
  3. pmc Advances in cancer therapy through the use of carbon nanotube-mediated targeted hyperthermia
    Cornel Iancu
    3rd Surgery Clinic, Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 6:1675-84. 2011
  4. ncbi Long term outcome following surgical treatment for distal gastric cancer
    Lucian Mocan
    Regional Institute of Gastroenterology and Hepatology 3rd Surgical Clinic, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 22:53-8. 2013
  5. pmc Selective ex-vivo photothermal ablation of human pancreatic cancer with albumin functionalized multiwalled carbon nanotubes
    Lucian Mocan
    Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 6:915-28. 2011
  6. pmc Open or laparoscopic treatment for hydatid disease of the liver? A 10-year single-institution experience
    Florin Zaharie
    Department of Surgery, Iuliu Hatieganu, University of Medicine and Pharmacy, Octavian Fodor Regional Institute of Gastroenterology and Hepatology, 19 21 Croitorilor Street, 400162, Cluj Napoca, Romania
    Surg Endosc 27:2110-6. 2013
  7. ncbi Contrast enhanced ultrasound and computer tomography diagnosis of solid and mixed pancreatic tumors - analysis of confounders
    Tudor Andrei Vasile
    Regional Institute of Gastroenterology and Hepatology Prof Dr Octavian Fodor, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 21:285-92. 2012
  8. ncbi Laparoscopic rectal resection versus conventional open approach for rectal cancer - a 4-year experience of a single center
    Florin Zaharie
    Regional Institute of Gastroenterology and Hepatology Octavian Fodor, Cluj Napoca, and University of Medicine and Pharmacy Iuliu Haţieganu, Cluj Napoca, Romania
    J BUON 20:1447-55. 2015
  9. pmc Surface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus
    Lucian Mocan
    3rd Surgery Clinic, Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 9:1453-61. 2014
  10. ncbi Double splenic artery pseudoaneurysm associating splenic infarction in chronic pancreatitis
    Andrada Seicean
    Regional Institute of Gastroenterology and Hepatology, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 21:313-5. 2012

Collaborators

  • Lucian Mocan
  • Florin Zaharie
  • Marcel Tantau
  • Valentin Muntean
  • Liviu Vlad
  • Teodora Mocan
  • Radu Badea
  • Andrada Seicean
  • Adrian Bartos
  • Dana Bartos
  • Tudor Andrei Vasile
  • Mihai Socaciu
  • Andrei Roman
  • Liliana Chiorean
  • Cristian T Matea
  • Flaviu Tabaran
  • Ioana Ilie
  • Claudiu Tomuş
  • Toader Zaharie
  • Roxana Stan-Iuga
  • Radu Seicean
  • Daniela Ionescu
  • Aurel Mironiuc
  • Ofelia Anton
  • Iulian Opincariu
  • Vasile Andreica
  • Roxana Sechel
  • Bianca Szabo
  • Caius Breazu
  • Doris Pelau
  • Tudor Ciuleanu
  • Angelica Mangrău
  • Irinel Oancea
  • Dana Iancu
  • Rareş Buiga
  • Roxana Zaharie
  • Razvan Ilie
  • Al Hajjar Nadim
  • Roxana Stan Iuga
  • Iurie Acalovschi
  • Diana Feier
  • Nadim al Hajjar
  • Ofelia Maria Anton
  • Oliviu Pascu
  • Nadim Al-Hajjar
  • Horatiu Vasian
  • Daniela Ion
  • Delia Deac
  • Simona Margarit
  • Raluca Bodea

Detail Information

Publications28

  1. doi Surface plasmon resonance-induced photoactivation of gold nanoparticles as mitochondria-targeted therapeutic agents for pancreatic cancer
    Lucian Mocan
    Iuliu Hatieganu University of Medicine and Pharmacy, Regional Institute of Gastroenterology and Hepatology, Department of Nanomedicine, Croitorilor Street, Cluj Napoca, Romania, 40264 439696 40264 439696
    Expert Opin Ther Targets 17:1383-93. 2013
    ..This phenomenon is frequently termed as surface plasmon resonance (SPR)...
  2. pmc Enhanced laser thermal ablation for the in vitro treatment of liver cancer by specific delivery of multiwalled carbon nanotubes functionalized with human serum albumin
    Cornel Iancu
    Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Third Surgery Clinic, Cluj Napoca, Romania
    Int J Nanomedicine 6:129-41. 2011
    ..These unique results may represent a major step in liver cancer treatment using nanolocalized thermal ablation by laser heating...
  3. pmc Advances in cancer therapy through the use of carbon nanotube-mediated targeted hyperthermia
    Cornel Iancu
    3rd Surgery Clinic, Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 6:1675-84. 2011
    ..This paper illustrates the potential of engineered CNTs as laser-activated photothermal agents for the selective nanophotothermolysis of cancer cells...
  4. ncbi Long term outcome following surgical treatment for distal gastric cancer
    Lucian Mocan
    Regional Institute of Gastroenterology and Hepatology 3rd Surgical Clinic, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 22:53-8. 2013
    ..This observation justifies the use of this procedure for the surgical therapy of the cancer of distal stomach...
  5. pmc Selective ex-vivo photothermal ablation of human pancreatic cancer with albumin functionalized multiwalled carbon nanotubes
    Lucian Mocan
    Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 6:915-28. 2011
    ..We have obtained a selective photothermal ablation of the malign tissue based on the selective internalization of MWCNTs with HSA cargo inside the pancreatic adenocarcinoma after the ex-vivo intra-arterial perfusion...
  6. pmc Open or laparoscopic treatment for hydatid disease of the liver? A 10-year single-institution experience
    Florin Zaharie
    Department of Surgery, Iuliu Hatieganu, University of Medicine and Pharmacy, Octavian Fodor Regional Institute of Gastroenterology and Hepatology, 19 21 Croitorilor Street, 400162, Cluj Napoca, Romania
    Surg Endosc 27:2110-6. 2013
    ..This study evaluated the results of laparoscopic treatment (compared with the open approach) in the context of a 10-year single-institution experience...
  7. ncbi Contrast enhanced ultrasound and computer tomography diagnosis of solid and mixed pancreatic tumors - analysis of confounders
    Tudor Andrei Vasile
    Regional Institute of Gastroenterology and Hepatology Prof Dr Octavian Fodor, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 21:285-92. 2012
    ..CEUS and CECT showed a good diagnostic performance in differentiating benign from malignant pancreatic tumors. Enhancement pattern and tumor nature (solid vs. cystic) are independent confounders between imaging and histological diagnosis...
  8. ncbi Laparoscopic rectal resection versus conventional open approach for rectal cancer - a 4-year experience of a single center
    Florin Zaharie
    Regional Institute of Gastroenterology and Hepatology Octavian Fodor, Cluj Napoca, and University of Medicine and Pharmacy Iuliu Haţieganu, Cluj Napoca, Romania
    J BUON 20:1447-55. 2015
    ..Another goal was to find the fastest and most accurate method of treatment for rectal cancer, along with establishing the advantages and disadvantages of the two surgical techniques, depending on cancer location and its stage...
  9. pmc Surface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus
    Lucian Mocan
    3rd Surgery Clinic, Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 9:1453-61. 2014
    ..These unique data may represent a step forward in the study of bactericidal effects of various nanomaterials, with applications in biology and medicine. ..
  10. ncbi Double splenic artery pseudoaneurysm associating splenic infarction in chronic pancreatitis
    Andrada Seicean
    Regional Institute of Gastroenterology and Hepatology, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 21:313-5. 2012
    ..Their association with splenic infarction was explained by ischemic pathogenesis...
  11. pmc Minimal invasive treatment of abdominal multiorgan echinococcosis
    Claudiu Tomuş
    Department of Surgery, Octavian Fodor, Regional Institute of Gastro Enterology and Hepatology, Cluj Napoca, Romania Iuliu Hatieganu, University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int Surg 98:61-4. 2013
    ..The postoperative images at 6 and 12 months showed a decrease in size of the remnant cystic cavities...
  12. doi Laparoscopic low anterior resection with total mesorectal excision for rectal cancer
    Florin Zaharie
    Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Hepatogastroenterology 59:405-8. 2012
    ..Here, we present a laparoscopic approach for rectal cancer treatment consisting in a wide resection of the rectum, including the entire fascia with the enclosed mesentery of the rectum...
  13. pmc Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus-ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor
    Lucian Mocan
    Nanomedicine Department, Regional Institute of Gastroenterology and Hepatology Octavian Fodor, University of Medicine and Pharmacy, Iuliu Hatieganu, Croitorilor, Cluj Napoca, Romania Department of Surgery, University of Medicine and Pharmacy, Iuliu Hatieganu, Croitorilor, Cluj Napoca, Romania
    Int J Nanomedicine 10:5435-45. 2015
    ..The presented results may become a new method of treating cancer cells by selective therapeutic vectors using nanolocalized thermal ablation by laser heating. ..
  14. pmc In Vitro Administration of Gold Nanoparticles Functionalized with MUC-1 Protein Fragment Generates Anticancer Vaccine Response via Macrophage Activation and Polarization Mechanism
    Teodora Mocan
    2 Department of Nanomedicine, Institute of Gastroenterology and Hepatology, 19 21 Croitorilor St, 400162 Cluj Napoca, Romania 3 Department of Physiology, Iuliu Hatieganu University of Medicine and Pharmacy, no 1 Clinicilor Street, 400006 Cluj Napoca, Romania
    J Cancer 6:583-92. 2015
    ..To our best knowledge this is the first study to evaluate the anticancer effects of a newly designed nano-biocompound on the complex antigen- processing apparatus of peritoneal macrophages. ..
  15. doi Malignant familial adenomatous polyposis treated by laparoscopic colectomy and ileal pouch anal anastomosis: a case report
    Florin Zaharie
    3rd Surgical Clinic, Iuliu Hatieganu University of Medicine and Pharmacy Prof Dr Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 23:445-8. 2014
    ..The histopathological report described a well differentiated rectal adenocarcinoma T1N1aMx developed on a tubulo-villous adenoma located on the rectosigmoid jonction, the rest of the polyps with benign histology...
  16. doi Implementing fast-track protocol for colorectal surgery: a prospective randomized clinical trial
    Daniela Ionescu
    Department of Anesthesia and Intensive Care, University of Medicine and Pharmacy, Iuliu Hatieganu, Cluj Napoca, Romania
    World J Surg 33:2433-8. 2009
    ..Fast-track protocols are followed by an enhanced recovery, early return to bowel function and to complete nutrition, and a reduced hospital stay. Our study was designed to implement fast-track protocol in our university hospital...
  17. doi Neuroendocrine tumor of gallbladder with liver and retroperitoneal metastases and a good response to the chemotherapeutical treatment
    Liliana Chiorean
    Department of Ultrasonography, Octavian Fodor Institute of Gastroenterology and Hepatology, Cluj Napoca, Romania
    J Med Ultrason (2001) 42:271-6. 2015
    ..The patient received chemotherapy with good response, followed by surgery with cholecystectomy and partial hepatectomy. ..
  18. pmc Nicotinamide-functionalized multiwalled carbon nanotubes increase insulin production in pancreatic beta cells via MIF pathway
    Ioana Ilie
    Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 8:3345-53. 2013
    ..The application and potential of NA combined with MWCNTs as an antidiabetic agent may represent the beginning of a new chapter in the nanomediated treatment of diabetes mellitus. ..
  19. ncbi Added value of intravenous contrast-enhanced ultrasound for characterization of cystic pancreatic masses: a prospective study on 37 patients
    Tudor Andrei Vasile
    Radiology Department, Regional Institute of Hepatology and Gastroenterology Octavian Fodor, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj Napoca, Romania
    Med Ultrason 14:108-14. 2012
    ..The aim of this study was to evaluate the added value of contrast-enhanced ultrasound (CEUS) in the pancreatic cystic mass (PCM) diagnosis by using a qualitative and quantitative analysis in order to make a relevant characterization...
  20. doi Splenic cystic lymphangioma with atypical ultrasound findings
    Andrei Roman
    Department of Ultrasonography, Octavian Fodor Institute of Gastroenterology and Hepatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    J Med Ultrason (2001) 43:99-105. 2016
    ..The tumor received histopathological confirmation after splenectomy. Various CT and MRI findings in splenic lymphangiomas have been described, but very few reports regarding CEUS exist to this point. ..
  21. doi Recent achievements in colorectal cancer diagnostic and therapy by the use of nanoparticles
    Adrian Bartos
    a Department of Surgery, Prof Dr Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj Napoca, Romania
    Drug Metab Rev 48:27-46. 2016
    ..The purpose of this review is to highlight the recent achievements of cancer research by use of nanomaterials, in the idea of finding the ideal composite, capable to simultaneous diagnostic and treat cancer. ..
  22. pmc Rational design of gold nanocarrier for the delivery of JAG-1 peptide
    Cristian T Matea
    3rd Surgery Clinic, Department of Nanomedicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    J Nanobiotechnology 13:41. 2015
    ....
  23. ncbi Biliary plastic stent as a matrix core for lithogenesis in the common bile duct: a rare cause of jaundice
    Dana Bartos
    Department of Surgery, Prof Octavian Fodor Regional Institute of Gastroeneterology and Hepatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 21:427-9. 2012
    ..We have not found referrals concerning the stone formation as a complication at the level of a biliary stent...
  24. doi Thoracoscopic and laparoscopic esophagectomy with cervical manual anastomosis for esophageal cancer
    Florin Zaharie
    Third Surgery Clinic, luliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Hepatogastroenterology 59:1835-9. 2012
    ....
  25. pmc Effective colon cancer prophylaxis in mice using embryonic stem cells and carbon nanotubes
    Teodora Mocan
    Department of Physiology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Int J Nanomedicine 6:1945-54. 2011
    ..However, at present, a true anticancer vaccine remains elusive. There are several lines of evidence showing that carbon nanotubes may be used to initiate and maintain immune responses...
  26. ncbi The role of i.v. and oral contrast enhanced ultrasonography in the characterization of gastric tumors. A preliminary study
    Radu Badea
    Department of Ultrasonography, 3rd Medical Clinic, Institute of Gastroenterology and Hepatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
    Med Ultrason 14:197-203. 2012
    ..To identify the diagnosis benefits of harmonics optimized i.v. contrast enhanced ultrasonography (CEUS) in the detection and characterization of several gastric neoplasms...
  27. ncbi The safety of endoscopic ultrasonography-guided drainage of pancreatic fluid collections without fluoroscopic control: a single tertiary center experience
    Andrada Seicean
    Third Medical Clinic, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj Napoca, Romania
    J Gastrointestin Liver Dis 20:39-45. 2011
    ..When fluoroscopy cannot be used, drainage can still be performed, but no data regarding the safety of such a procedure have yet been published...
  28. ncbi Host-related predictive factors for anastomotic leakage following large bowel resections for colorectal cancer
    Cornel Iancu
    Department of Surgical Disciplines, University of Medicine and Pharmacy Iuliu Hatieganu, 3rd Surgery Clinic, Croitorilor Str 19 21, 400162 Cluj Napoca, Romania
    J Gastrointestin Liver Dis 17:299-303. 2008
    ..To identify the risk, the host-related prognostic factors and their predictive value for anastomotic leakage after colorectal resections following cancer...