Thomas Rimmelé

Summary

Publications

  1. pmc Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study
    Boris Jung
    Intensive Care Unit, Department of Anaesthesia and Critical Care, Saint Eloi Teaching Hospital, Universite Montpellier 1, 80 avenue Augustin Fliche, F 34295 Montpellier, Cedex 5, France
    Crit Care 15:R238. 2011
  2. pmc Clinical review: blood purification for sepsis
    Thomas Rimmelé
    The CRISMA Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Crit Care 15:205. 2011
  3. doi request reprint High-volume hemofiltration in the intensive care unit: a blood purification therapy
    Thomas Rimmelé
    Department of Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, University Claude Bernard Lyon1, Lyon, France
    Anesthesiology 116:1377-87. 2012
  4. ncbi request reprint Pharmacokinetics and intrapulmonary diffusion of levofloxacin in critically ill patients with severe community-acquired pneumonia
    Emmanuel Boselli
    Department of Anesthesiology and Intensive Care, Hotel Dieu Hospital, Lyon, France
    Crit Care Med 33:104-9. 2005
  5. ncbi request reprint Pharmacokinetics and intrapulmonary concentrations of linezolid administered to critically ill patients with ventilator-associated pneumonia
    Emmanuel Boselli
    Department of Anesthesiology and Intensive Care, Edouard Herriot Hospital, Lyon, France
    Crit Care Med 33:1529-33. 2005
  6. pmc Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purification in experimental sepsis
    Zhi Yong Peng
    The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Kidney Int 81:363-9. 2012
  7. doi request reprint Blood purification in sepsis: a new paradigm
    Zhiyong Peng
    Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Contrib Nephrol 165:322-8. 2010
  8. pmc Bactericidal antibiotics temporarily increase inflammation and worsen acute kidney injury in experimental sepsis
    Zhi Yong Peng
    Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 40:538-43. 2012
  9. pmc Development of venovenous extracorporeal blood purification circuits in rodents for sepsis
    Zhi Yong Peng
    The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Electronic address
    J Surg Res 185:790-6. 2013
  10. doi request reprint Alveolar diffusion and pharmacokinetics of linezolid administered in continuous infusion to critically ill patients with ventilator-associated pneumonia
    Emmanuel Boselli
    Department of Anaesthesiology and Intensive Care, Edouard Herriot Hospital, HCL, University of Lyon, Lyon, France
    J Antimicrob Chemother 67:1207-10. 2012

Collaborators

Detail Information

Publications23

  1. pmc Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study
    Boris Jung
    Intensive Care Unit, Department of Anaesthesia and Critical Care, Saint Eloi Teaching Hospital, Universite Montpellier 1, 80 avenue Augustin Fliche, F 34295 Montpellier, Cedex 5, France
    Crit Care 15:R238. 2011
    ..In this study, we sought describe the incidence and outcomes of severe metabolic or mixed acidemia in critically ill patients as well as the use of sodium bicarbonate therapy to treat these illnesses...
  2. pmc Clinical review: blood purification for sepsis
    Thomas Rimmelé
    The CRISMA Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Crit Care 15:205. 2011
    ....
  3. doi request reprint High-volume hemofiltration in the intensive care unit: a blood purification therapy
    Thomas Rimmelé
    Department of Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, University Claude Bernard Lyon1, Lyon, France
    Anesthesiology 116:1377-87. 2012
    ..Conversely, much experimental and some clinical evidence suggest that high-volume hemofiltration can be beneficial for the subset of critically ill patients with severe inflammatory states such as septic shock...
  4. ncbi request reprint Pharmacokinetics and intrapulmonary diffusion of levofloxacin in critically ill patients with severe community-acquired pneumonia
    Emmanuel Boselli
    Department of Anesthesiology and Intensive Care, Hotel Dieu Hospital, Lyon, France
    Crit Care Med 33:104-9. 2005
    ..To determine the steady-state plasma and epithelial lining fluid concentrations of intravenous levofloxacin, 500 mg, administered once or twice daily in critically ill patients with severe community-acquired pneumonia...
  5. ncbi request reprint Pharmacokinetics and intrapulmonary concentrations of linezolid administered to critically ill patients with ventilator-associated pneumonia
    Emmanuel Boselli
    Department of Anesthesiology and Intensive Care, Edouard Herriot Hospital, Lyon, France
    Crit Care Med 33:1529-33. 2005
    ..To determine the steady-state plasma pharmacokinetic variables and epithelial lining fluid concentrations of linezolid administered to critically ill patients with ventilator-associated pneumonia...
  6. pmc Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purification in experimental sepsis
    Zhi Yong Peng
    The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Kidney Int 81:363-9. 2012
    ..These results may have important implications for the design and conduct of future trials in sepsis including defining alternative targets for extracorporeal blood purification and other therapies...
  7. doi request reprint Blood purification in sepsis: a new paradigm
    Zhiyong Peng
    Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Contrib Nephrol 165:322-8. 2010
    ..Finally, the emerging paradigm of sepsis-induced immune suppression provides additional rationale for the development of extracorporeal blood purification therapy for sepsis...
  8. pmc Bactericidal antibiotics temporarily increase inflammation and worsen acute kidney injury in experimental sepsis
    Zhi Yong Peng
    Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 40:538-43. 2012
    ..To explore the relationships among bactericidal antimicrobial treatment of sepsis, inflammatory response, severity of acute kidney injury, and outcomes...
  9. pmc Development of venovenous extracorporeal blood purification circuits in rodents for sepsis
    Zhi Yong Peng
    The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Electronic address
    J Surg Res 185:790-6. 2013
    ..We developed a venovenous (VV) purification model in the rat as an adjunct for the treatment of sepsis...
  10. doi request reprint Alveolar diffusion and pharmacokinetics of linezolid administered in continuous infusion to critically ill patients with ventilator-associated pneumonia
    Emmanuel Boselli
    Department of Anaesthesiology and Intensive Care, Edouard Herriot Hospital, HCL, University of Lyon, Lyon, France
    J Antimicrob Chemother 67:1207-10. 2012
    ..This study aimed to determine the steady-state serum and alveolar concentrations of linezolid administered by continuous infusion to critically ill patients with ventilator-associated pneumonia (VAP)...
  11. doi request reprint In vivo antibiotic removal during coupled plasma filtration adsorption: a retrospective study
    Mathieu Page
    From the Department of Anesthesiology and Critical Care Medicine, Pavilion P, Edouard Herriot Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon 1, Lyon, France Laboratory of Toxicology and Biochemistry, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Claude Bernard University Lyon 1, Pierre Benite, France and The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    ASAIO J 60:70-5. 2014
    ..Thus, as opposed to tazobactam, we report high adsorption of piperacillin and vancomycin on the CPFA resin but with no reduction in serum concentrations...
  12. ncbi request reprint Comparison of inflammatory response during on-pump and off-pump coronary artery bypass surgery
    Thomas Rimmelé
    The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 1526, USA
    Int J Artif Organs 33:131-8. 2010
    ..However with the development of polymer-coated biocompatible extracorporeal circuits, we wanted to see if cardiopulmonary bypass still played an important role in triggering this inflammatory response...
  13. pmc What blood temperature for an ex vivo extracorporeal circuit?
    Thomas Rimmelé
    The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Artif Organs 35:593-601. 2011
    ..Investigators in this field must be aware of the fact that blood temperature is a crucial confounding parameter and the type of "background noise" they will face depending on the strategy adopted...
  14. doi request reprint Use of loop diuretics in the critically ill
    Thomas Rimmelé
    The Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Contrib Nephrol 165:219-25. 2010
    ..We will briefly review the available evidence for and against the use of diuretics in the critically ill, including cardiorenal syndromes...
  15. ncbi request reprint Immediate postoperative refeeding in orthopedic surgery is safe
    Thomas Rimmelé
    Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, 5 Place d Arsonval, 69003 Lyon, France
    J Anesth 19:323-4. 2005
    ..Our results suggest that immediate postoperative refeeding after orthopedic surgery is safe, does not increase postoperative nausea and vomiting, and probably increases the comfort of patients...
  16. pmc Isolation of Aspergillus in three 2009 H1N1 influenza patients
    Amesh A Adalja
    Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15212, USA
    Influenza Other Respir Viruses 5:225-9. 2011
    ..To describe the association of Aspergillus with influenza...
  17. ncbi request reprint Background infusion is not beneficial during labor patient-controlled analgesia with 0.1% ropivacaine plus 0.5 microg/ml sufentanil
    Emmanuel Boselli
    Service d Anesthesie Reanimation, Hotel Dieu, Lyon, France
    Anesthesiology 100:968-72. 2004
    ....
  18. doi request reprint Optimal remifentanil dose for laryngeal mask airway insertion when co-administered with a single standard dose of propofol
    Lionel Bouvet
    Department of Anesthesia and Intensive Care, Edouard Herriot Hospital, Hospices Civils de Lyon, 5 Place d Arsonval, Lyon, France
    Can J Anaesth 57:222-9. 2010
    ..This dose-response study aimed to determine the optimal dose of remifentanil combined with propofol 2.5 mg.kg(-1) iv in order to achieve excellent conditions for laryngeal mask airway (LMA) insertion in 95% of adult female patients...
  19. doi request reprint Oliguria and fluid overload
    Thomas Rimmelé
    The CRISMA Clinical Research, Investigation, and Systems Modeling of Acute Illness Laboratory, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Contrib Nephrol 164:39-45. 2010
    ..The aim of this short review is to point out the deleterious effects of these two related clinical situations emphasizing their pathophysiology...
  20. ncbi request reprint Early relaparotomy after simultaneous pancreas-kidney transplantation
    Mathieu Page
    Department of Anesthesiology and Intensive Care Medicine, Pavilion P, Edouard Herriot Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon 1, Lyon, France
    Transplantation 94:159-64. 2012
    ..The aim of this study was to assess the incidence, causes, and risk factors of early relaparotomy after SPKT...
  21. doi request reprint High-volume haemofiltration with a new haemofiltration membrane having enhanced adsorption properties in septic pigs
    Thomas Rimmelé
    Department of Anesthesiology and Intensive Care, Pavilion P, Edouard Herriot Hospital, Lyon, France
    Nephrol Dial Transplant 24:421-7. 2009
    ..The aim of this study was to determine the haemodynamic and immunological effects of a new haemofiltration membrane, which has enhanced adsorption properties due to a special surface treatment, allowing the adsorption of endotoxins...
  22. pmc N-acetylcysteine is effective for prevention but not for treatment of folic acid-induced acute kidney injury in mice
    Hong zhi Wang
    Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Crit Care Med 39:2487-94. 2011
    ..There is controversy regarding the benefits of N-acetylcysteine in acute kidney injury. This study was to compare three commonly used regimens and explore which regimen is best for the protection of acute kidney injury...