Genomes and Genes

Species

Fabiola M Ribeiro

Summary

Publications

  1. doi request reprint Metabotropic glutamate receptor 5 as a potential therapeutic target in Huntington's disease
    Fabiola M Ribeiro
    Universidade Federal de Minas Gerais, Departamento de Bioquimica e Imunologia, ICB, Belo Horizonte 31270 901, Brazil
    Expert Opin Ther Targets 18:1293-304. 2014
  2. pmc Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis
    Maryse Paquet
    J, Allyn Taylor Centre for Cell Biology, Robarts Research Institute, Department of Physiology and Pharmacology, The University of Western Ontario, 100 Perth Drive, London, ON, N6A 5K8, Canada
    Mol Brain 6:9. 2013
  3. pmc The metabotropic glutamate receptor 5 role on motor behavior involves specific neural substrates
    Isabella M Guimaraes
    Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270 901, Brazil
    Mol Brain 8:24. 2015
  4. pmc Alzheimer's disease: Targeting the Cholinergic System
    Talita H Ferreira-Vieira
    Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Curr Neuropharmacol 14:101-15. 2016
  5. doi request reprint Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease
    Fabiola M Ribeiro
    Departamento de Bioquimica e Imunologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte 31270 901, Brazil
    Hum Mol Genet 23:2030-42. 2014
  6. doi request reprint The Phoneutria nigriventer spider toxin, PnTx4-5-5, promotes neuronal survival by blocking NMDA receptors
    Flavia R Silva
    Department of Biochemistry and Immunology, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Toxicon 112:16-21. 2016
  7. doi request reprint Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity
    Luciano R Vilela
    Graduate Program in Neuroscience, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    Toxicol Appl Pharmacol 286:178-87. 2015

Collaborators

  • Flavia R Silva
  • Talita H Ferreira-Vieira
  • Isabella M Guimaraes
  • Grace S Pereira
  • Luciano R Vilela
  • Maryse Paquet
  • Christopher Kushmerick
  • Marcus V Gomez
  • Edleusa M L Batista
  • Luciene B Vieira
  • Marta N Cordeiro
  • Juliana F da Silva
  • Antonio Carlos P de Oliveira
  • Daniele C Aguiar
  • Flávia Rodrigues
  • Stephen Sg Ferguson
  • Pedro H Gobira
  • Fabricio A Moreira
  • Toniana G Carvalho
  • Marcio F D Moraes
  • Daniel C Medeiros
  • André R Massessini
  • Thercia G Viana
  • Juliana G Doria
  • Jessica L Esseltine
  • Jennifer Guadagno
  • Sean P Cregan
  • Stephen S G Ferguson

Detail Information

Publications7

  1. doi request reprint Metabotropic glutamate receptor 5 as a potential therapeutic target in Huntington's disease
    Fabiola M Ribeiro
    Universidade Federal de Minas Gerais, Departamento de Bioquimica e Imunologia, ICB, Belo Horizonte 31270 901, Brazil
    Expert Opin Ther Targets 18:1293-304. 2014
    ..Glutamate has been implicated in a number of neurodegenerative diseases, and several studies suggest that the metabotropic glutamate receptor 5 (mGluR5) may represent a target for the treatment of HD...
  2. pmc Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis
    Maryse Paquet
    J, Allyn Taylor Centre for Cell Biology, Robarts Research Institute, Department of Physiology and Pharmacology, The University of Western Ontario, 100 Perth Drive, London, ON, N6A 5K8, Canada
    Mol Brain 6:9. 2013
    ..The expression of mGluR5 in astrocytes has been shown to be increased in several acute and chronic neurodegenerative conditions, but little is known about the functional relevance of mGluR5 up-regulation in astrocytes following injury...
  3. pmc The metabotropic glutamate receptor 5 role on motor behavior involves specific neural substrates
    Isabella M Guimaraes
    Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270 901, Brazil
    Mol Brain 8:24. 2015
    ..Moreover, increased locomotor activity can also be observed in mice following the genetic deletion of mGluR5. However, it is still unclear which specific brain substrates contribute to mGluR5-mediated regulation of motor function...
  4. pmc Alzheimer's disease: Targeting the Cholinergic System
    Talita H Ferreira-Vieira
    Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Curr Neuropharmacol 14:101-15. 2016
    ..Thus, drugs that act on the cholinergic system represent a promising option to treat AD patients. ..
  5. doi request reprint Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease
    Fabiola M Ribeiro
    Departamento de Bioquimica e Imunologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte 31270 901, Brazil
    Hum Mol Genet 23:2030-42. 2014
    ..Thus, our data suggest that mutant huntingtin protein and mGluR5 exhibit a functional interaction that may be important for HD-mediated alterations in locomotor behavior and the development of intranuclear inclusions. ..
  6. doi request reprint The Phoneutria nigriventer spider toxin, PnTx4-5-5, promotes neuronal survival by blocking NMDA receptors
    Flavia R Silva
    Department of Biochemistry and Immunology, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Toxicon 112:16-21. 2016
    ..Moreover, the toxin is also able to protect WT neurons against amyloid β (Aβ) peptide toxicity. These results indicate that the toxin PnTx4-5-5 is a potential neuroprotective drug. ..
  7. doi request reprint Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity
    Luciano R Vilela
    Graduate Program in Neuroscience, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    Toxicol Appl Pharmacol 286:178-87. 2015
    ..This strategy may be further explored in the development of treatments for drug-induced neurotoxicity. ..