A Psyrri

Summary

Publications

  1. doi request reprint The promise of immunotherapy in head and neck squamous cell carcinoma
    P Economopoulou
    Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National Kapodistrian University of Athens, School of Medicine, Athens
    Ann Oncol 27:1675-85. 2016
  2. doi request reprint The current and future impact of human papillomavirus on treatment of squamous cell carcinoma of the head and neck
    A Psyrri
    Department of Medicine, Section of Medical Oncology, Attikon University Hospital, Athens, Greece
    Ann Oncol 25:2101-15. 2014
  3. pmc Feasibility of Induction Docetaxel, Cisplatin, 5-Fluorouracil, Cetuximab (TPF-C) Followed by Concurrent Cetuximab Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
    Nikolaos Charalambakis
    Second Department of Internal Medicine Propaedeutic, Oncology Section, Attikon University Hospital, University of Athens Medical School Athens, Greece
    Front Oncol 3:5. 2013
  4. pmc Future directions in research, treatment and prevention of HPV-related squamous cell carcinoma of the head and neck
    Amanda Psyrri
    2nd Department of Internal Medicine, Attikon Hospital, National Kapodistrian University of Athens, 12462 Athens, Greece
    Head Neck Pathol 6:S121-8. 2012
  5. ncbi request reprint Human papillomavirus-related head and neck tumors: clinical and research implication
    Amanda Psyrri
    Second Department of Internal Medicine, Attikon University Hospital, Athens, Greece
    Curr Opin Oncol 21:201-5. 2009
  6. pmc Strategies to promote translational research within the European Organisation for Research and Treatment of Cancer (EORTC) Head and Neck Cancer Group: a report from the Translational Research Subcommittee
    A Psyrri
    Second Department of Internal Medicine, Propaedeutic, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Ann Oncol 21:1952-60. 2010
  7. doi request reprint Prospective, open-label, randomized, phase III study of two dose-dense regimens MVAC versus gemcitabine/cisplatin in patients with inoperable, metastatic or relapsed urothelial cancer: a Hellenic Cooperative Oncology Group study (HE 16/03)
    A Bamias
    Department of Clinical Therapeutics, Alexandra Hospital, Athens University Medical School, Athens, Greece
    Ann Oncol 24:1011-7. 2013
  8. doi request reprint Carboplatin/gemcitabine alternating with carboplatin/pegylated liposomal doxorubicin and carboplatin/cyclophosphamide in platinum-refractory/resistant paclitaxel - pretreated ovarian carcinoma
    D Pectasides
    Second Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, University General Hospital Attikon, Rimini 1, Haidari, Athens, Greece
    Gynecol Oncol 118:52-7. 2010
  9. doi request reprint Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study
    A Psyrri
    Second Department of Internal Medicine, Attikon University Hospital, Athens
    Ann Oncol 23:1422-7. 2012
  10. ncbi request reprint H-RAS and PIK3CA mutations and response to cetuximab in head and neck squamous cell carcinoma (HNSCC)
    T Rampias
    BRFAA, New Haven, CT Attiko hospital, Athens, Greece Yale University, New Haven, CT Hellenic Cooperative Oncology Group HeCOG, Athens, Greece Hellenic Cooperative Oncology Group Data Office, Athens, Greece University of Athens, Athens, Greece
    J Clin Oncol 29:5513. 2011

Collaborators

Detail Information

Publications26

  1. doi request reprint The promise of immunotherapy in head and neck squamous cell carcinoma
    P Economopoulou
    Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National Kapodistrian University of Athens, School of Medicine, Athens
    Ann Oncol 27:1675-85. 2016
    ..Herein, we provide a comprehensive review of immune escape mechanisms in HNSCC, as well as current immunotherapy approaches under investigation. ..
  2. doi request reprint The current and future impact of human papillomavirus on treatment of squamous cell carcinoma of the head and neck
    A Psyrri
    Department of Medicine, Section of Medical Oncology, Attikon University Hospital, Athens, Greece
    Ann Oncol 25:2101-15. 2014
    ..Furthermore, HPV-associated oropharyngeal carcinoma (OPC) appears to be a distinct entity with different epidemiology, biology, and clinical outcomes...
  3. pmc Feasibility of Induction Docetaxel, Cisplatin, 5-Fluorouracil, Cetuximab (TPF-C) Followed by Concurrent Cetuximab Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
    Nikolaos Charalambakis
    Second Department of Internal Medicine Propaedeutic, Oncology Section, Attikon University Hospital, University of Athens Medical School Athens, Greece
    Front Oncol 3:5. 2013
    ..Conclusion: The combination of induction TPF-C with concurrent cetuximab radioimmunotherapy in patients with locally advanced HNSCC is tolerable, with encouraging efficacy...
  4. pmc Future directions in research, treatment and prevention of HPV-related squamous cell carcinoma of the head and neck
    Amanda Psyrri
    2nd Department of Internal Medicine, Attikon Hospital, National Kapodistrian University of Athens, 12462 Athens, Greece
    Head Neck Pathol 6:S121-8. 2012
    ..This review summarizes the main events of HPV-induced carcinogenesis with an emphasis on the implications of these carcinogenic mechanisms on research, treatment and prevention of HPV-associated OSCC...
  5. ncbi request reprint Human papillomavirus-related head and neck tumors: clinical and research implication
    Amanda Psyrri
    Second Department of Internal Medicine, Attikon University Hospital, Athens, Greece
    Curr Opin Oncol 21:201-5. 2009
    ..The demonstration that HPV is causally associated with a subset of HNSCC has tremendous clinical and research implications...
  6. pmc Strategies to promote translational research within the European Organisation for Research and Treatment of Cancer (EORTC) Head and Neck Cancer Group: a report from the Translational Research Subcommittee
    A Psyrri
    Second Department of Internal Medicine, Propaedeutic, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Ann Oncol 21:1952-60. 2010
    ..In the present report, we summarize our strategic plans to promote head and neck cancer research within the EORTC framework...
  7. doi request reprint Prospective, open-label, randomized, phase III study of two dose-dense regimens MVAC versus gemcitabine/cisplatin in patients with inoperable, metastatic or relapsed urothelial cancer: a Hellenic Cooperative Oncology Group study (HE 16/03)
    A Bamias
    Department of Clinical Therapeutics, Alexandra Hospital, Athens University Medical School, Athens, Greece
    Ann Oncol 24:1011-7. 2013
    ..However, the role of GC intensification has not been studied. We conducted a randomized, phase III study comparing a DD-GC regimen with DD-MVAC in advanced UC...
  8. doi request reprint Carboplatin/gemcitabine alternating with carboplatin/pegylated liposomal doxorubicin and carboplatin/cyclophosphamide in platinum-refractory/resistant paclitaxel - pretreated ovarian carcinoma
    D Pectasides
    Second Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, University General Hospital Attikon, Rimini 1, Haidari, Athens, Greece
    Gynecol Oncol 118:52-7. 2010
    ..In this phase II study the efficacy and toxicity of an alternating chemotherapy regimen was examined in platinum-resistant relapsed epithelial ovarian cancer (EOC) patients...
  9. doi request reprint Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study
    A Psyrri
    Second Department of Internal Medicine, Attikon University Hospital, Athens
    Ann Oncol 23:1422-7. 2012
    ..In the present study, we sought to explore the prognostic and/or predictive significance of UBE2C messenger RNA (mRNA) expression on disease-free survival (DFS) and overall survival (OS) in high-risk operable breast cancer patients...
  10. ncbi request reprint H-RAS and PIK3CA mutations and response to cetuximab in head and neck squamous cell carcinoma (HNSCC)
    T Rampias
    BRFAA, New Haven, CT Attiko hospital, Athens, Greece Yale University, New Haven, CT Hellenic Cooperative Oncology Group HeCOG, Athens, Greece Hellenic Cooperative Oncology Group Data Office, Athens, Greece University of Athens, Athens, Greece
    J Clin Oncol 29:5513. 2011
    ..The prevalence of H-RAS and PIK3CA mutations has not been studied extensively in Caucasian populations. We sought to determine the impact of H-ras and PIK3CA gene mutations on resistance to cetuximab in head and neck cancer...
  11. ncbi request reprint Gastric metastases originating from breast cancer: report of 8 cases and review of the literature
    D Pectasides
    Second Department of Internal Medicine, Attikon University Hospital, Rimini 1, Haidari, Athens, Greece
    Anticancer Res 29:4759-63. 2009
    ....
  12. ncbi request reprint PIK3CA as a molecular target in mantle cell lymphoma
    S Papageorgiou
    University of Athens Medical School, University General Hospital, Haidari, Greece University of Athens, Athens, Greece Evangelismos Hospital, Athens, Greece University General Hospital, Haidari, Greece
    J Clin Oncol 26:8612. 2008
    ..8612 Background: We sought to determine the contribution of PIK3CA gene alterations to the pathogenesis of mantle cell lymphoma (MCL). PIK3CA is known to be involved in the PI 3-kinase/AKT signaling pathway, which is activated in MCL...
  13. ncbi request reprint Molecular prognostic markers in squamous cell carcinoma of the head and neck: the role of E-cadherin
    P Kountourakis
    Yale University, New Haven, CT Fox Chase Cancer Center, Philadelphia, PA University of Athens, Athens, Greece University of Thessaloniki, Thessaloniki, Greece
    J Clin Oncol 26:6040. 2008
    ..In the present study we investigated the relationship between membranous E-cadherin expression and outcome in patients with head and neck squamous cell carcinoma (HNSCC)...
  14. doi request reprint Beyond BRCA: new hereditary breast cancer susceptibility genes
    P Economopoulou
    Oncology Unit, 2nd Department of Internal Medicine, Attikon University Hospital, National Kapodistrian University of Athens, Greece Electronic address
    Cancer Treat Rev 41:1-8. 2015
    ..This review will summarize current data on new findings in breast cancer susceptibility genes. ..
  15. doi request reprint The mutational spectrum of squamous-cell carcinoma of the head and neck: targetable genetic events and clinical impact
    G Mountzios
    Department of Medical Oncology, University of Athens School of Medicine, Athens, Greece
    Ann Oncol 25:1889-900. 2014
    ..We also discuss the potential integration of new data within the framework of precision cancer medicine. ..
  16. doi request reprint RAS/PI3K crosstalk and cetuximab resistance in head and neck squamous cell carcinoma
    T Rampias
    Authors Affiliations Department of Surgery, Yale University School of Medicine, New Haven, Connecticut Department of Medicine, Attikon Hospital and Department of Biochemistry and Molecular Biology, Faculty of Biology, National Kapodistrian University of Athens, University of Athens, Greece
    Clin Cancer Res 20:2933-46. 2014
    ..Despite great clinical promise, intrinsic or acquired cetuximab resistance hinders successful treatment outcomes but little is known about the underlying mechanism...
  17. ncbi request reprint Radiotherapy for Hodgkin's lymphoma: too hard to die?
    A G Zygogianni
    Iaso Private Hospital, Radiotherapy Department, Athens, Greece
    J BUON 17:116-23. 2012
    ..Analysis of randomized studies supports the inclusion of reduced-field and dose of RT in the radiotherapeutic treatment options for HL. RT is an integral part of the combined-modality therapy (CMT) of HL...
  18. doi request reprint Testicular function in poor-risk nonseminomatous germ cell tumors treated with methotrexate, paclitaxel, ifosfamide, and cisplatin combination chemotherapy
    D Pectasides
    Second Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Rimini 1, Haidari, Athens, Greece
    J Androl 30:280-6. 2009
    ..The majority of men with poor-risk germ cell tumors who were treated with the M-TIP regimen demonstrated recovery spermatogenesis after treatment, and Leydig cell function was unaffected...
  19. doi request reprint Optimizing approaches to head-and-neck cancers. Viruses in head-and-neck cancers: prevention and therapy
    A Psyrri
    Second Department of Internal Medicine, Attikon University Hospital, Athens, Greece
    Ann Oncol 19:vii189-94. 2008
  20. doi request reprint Carboplatin and paclitaxel in metastatic or recurrent cervical cancer
    Dimitrios Pectasides
    2nd Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Athens, Greece
    Int J Gynecol Cancer 19:777-81. 2009
    ..The purpose of this study was to evaluate the activity and toxicity of carboplatin and paclitaxel combination in advanced or recurrent carcinoma of the cervix...
  21. ncbi request reprint Loss of tumour suppressor p16 expression in initial stages of oral oncogenesis
    Eleftherios Vairaktaris
    Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
    Anticancer Res 27:979-84. 2007
    ..p16 expression in sequential histological stages of oral squamous cell carcinoma (OSCC) formation was investigated using an experimental model of induced oral carcinogenesis in Syrian golden hamsters...
  22. ncbi request reprint Gemcitabine and pegylated liposomal doxorubicin alternating with cisplatin plus cyclophosphamide in platinum refractory/resistant, paclitaxel-pretreated, ovarian carcinoma
    Dimitrios Pectasides
    2nd Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Haidari, 1 Rimini, Athens, Greece
    Gynecol Oncol 108:47-52. 2008
    ....
  23. ncbi request reprint Treatment issues in clear cell carcinoma of the ovary: a different entity?
    Dimitrios Pectasides
    Second Department of Internal Medicine, Oncology Section, University of Athens, Greece
    Oncologist 11:1089-94. 2006
    ..Our goal was to review the clinical features and management of patients with OCCC...
  24. ncbi request reprint Combination chemotherapy with docetaxel, vinorelbine and estramustine phosphate in metastatic androgen-resistant prostate cancer: a single institution experience
    Dimitrios Pectasides
    Second Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Haidari, Athens, Greece
    Anticancer Res 29:769-75. 2009
    ..The aim of this study was to evaluate the activity and toxicity of docetaxel, vinorelbine and oral estramustine in androgen-resistant prostate cancer (ARPC)...
  25. pmc Hybrid capture vs. PCR screening of cervical human papilloma virus infections. Cytological and histological associations in 1270 women
    Sotirios Tsiodras
    Department of Cytopathology, Attikon University Hospital, University of Athens Med, Sch, Athens, Greece
    BMC Cancer 10:53. 2010
    ..We evaluated two molecular methods of HPV detection and their correlation with cytological and histological diagnosis in a large sample of Greek women...
  26. doi request reprint Activation of Wnt signaling pathway by human papillomavirus E6 and E7 oncogenes in HPV16-positive oropharyngeal squamous carcinoma cells
    Theodore Rampias
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Mol Cancer Res 8:433-43. 2010
    ..In addition, we show the significance of the endogenous Siah-1-dependent ubiquitin/proteasome pathway for beta-catenin degradation and its regulation by E6/E7 viral oncoproteins in HPV16-positive oropharyngeal cancer cells...