- A reanalysis of IgM Western blot criteria for the diagnosis of early Lyme diseaseR Porwancher
Department of Medicine, St Francis Medical Center, Trenton, NJ 08629, USA
J Infect Dis 179:1021-4. 1999..The value of the two-step approach for diagnosis of early Lyme disease may be limited in populations at lower risk of disease or when patients present with atypical signs and symptoms...
- Multiplex immunoassay for Lyme disease using VlsE1-IgG and pepC10-IgM antibodies: improving test performance through bioinformaticsRichard B Porwancher
Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ, USA
Clin Vaccine Immunol 18:851-9. 2011..1% to 17.1%). As a second-tier test, a multiplex assay for VlsE1-IgG and pepC10-IgM antibodies performed as well as or better than Western blotting for Lyme disease diagnosis. Prospective validation studies appear to be warranted...
- Improving Lyme disease diagnosis through bioinformaticsRichard Porwancher; Fiscal Year: 2008..This bioinformatic approach has the potential for integrating clinical and serologic diagnostic approaches using a standardized serum bank. ..