Didier Cabanes

Summary

Affiliation: Rua do Campo Alegre
Country: Portugal

Publications

  1. doi request reprint Animal models of Listeria infection
    Didier Cabanes
    Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular IBMC, Universidade do Porto, Portugal
    Curr Protoc Microbiol . 2008
  2. doi request reprint LapB, a novel Listeria monocytogenes LPXTG surface adhesin, required for entry into eukaryotic cells and virulence
    Olga Reis
    Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
    J Infect Dis 202:551-62. 2010
  3. ncbi request reprint In Vivo Transcriptional Profiling of Listeria monocytogenes and Mutagenesis Identify New Virulence Factors Involved in Infection
    Ana Camejo
    IBMC Instituto de Biologia Molecular e Celular, Group of Molecular Microbiology, Universidade do Porto, Oporto, Portugal
    PLoS Pathog 5:e1000449. 2009
  4. doi request reprint The arsenal of virulence factors deployed by Listeria monocytogenes to promote its cell infection cycle
    Ana Camejo
    Group of Molecular Microbiology, IBMC Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
    Virulence 2:379-94. 2011
  5. doi request reprint Extraction of cell wall-bound teichoic acids and surface proteins from Listeria monocytogenes
    Filipe Carvalho
    Group of Molecular Microbiology, Institute for Molecular and Cell Biology, Porto, Portugal
    Methods Mol Biol 966:289-308. 2013
  6. ncbi request reprint Listeria monocytogenes encodes a functional ESX-1 secretion system whose expression is detrimental to in vivo infection
    Jorge Pinheiro
    a Instituto de Investigação e Inovação em Saúde i3S, Universidade do Porto, Porto, Portugal
    Virulence . 2016
  7. pmc Listeria monocytogenes triggers the cell surface expression of Gp96 protein and interacts with its N terminus to support cellular infection
    Mariana Martins
    Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Universidade do Porto, 4150 180 Porto, Portugal
    J Biol Chem 287:43083-93. 2012
  8. pmc L-Rhamnosylation of Listeria monocytogenes Wall Teichoic Acids Promotes Resistance to Antimicrobial Peptides by Delaying Interaction with the Membrane
    Filipe Carvalho
    Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Porto, Portugal Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal
    PLoS Pathog 11:e1004919. 2015
  9. pmc Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection
    Maria Teresa Almeida
    From the Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200 Porto, Portugal, the Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Universidade do Porto, 4150 180 Porto, Portugal, the Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050 313 Porto, Portugal
    J Biol Chem 290:8383-95. 2015
  10. pmc Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins
    Francisco Sarmento Mesquita
    I3S Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
    EMBO Rep . 2016

Collaborators

  • P Cossart
  • Carmen Buchrieser
  • Marc Lecuit
  • Olivier Dussurget
  • Serge Mostowy
  • Helene Bierne
  • F Garcia-del Portillo
  • Sandra Sousa
  • Filipe Carvalho
  • Ana Camejo
  • Olga Reis
  • Claudia Brito
  • Maria Teresa Almeida
  • Mariana Martins
  • Elsa Leitão
  • Francisco Sarmento Mesquita
  • Jorge Pinheiro
  • Rita Pombinho
  • Rafael Custodio
  • Pierre Ferreira
  • Edith Gouin
  • Valeria Dellaretti Guimarães
  • Christophe Sabet
  • Luisa Zanolli Moreno
  • Ines M Moura
  • Ana Vieira
  • Maria J Mazon Moya
  • M Graciela Pucciarelli
  • Jorge Campos Pinheiro
  • Magda L Atilano
  • Gonçalo Covas
  • David W Holden
  • Hugo Osorio
  • Sergio R Filipe
  • Rui Cruz
  • Richard L Gallo
  • Francisco S Mesquita
  • John M Leong
  • Didier Vingadassalom
  • Lionel Costa
  • Ana Catarina Costa
  • María Graciela Pucciarelli
  • Véronique Villiers
  • Elisabeth Couve
  • Guy Tran-Van-Nhieu
  • Philippe Sansonetti
  • Laurence Bougnères
  • Cristel Archambaud
  • Michel Popoff
  • Vasco Azevedo
  • Pierre Legrain
  • Alexandra Gruss
  • Frederic Colland
  • Stéphanie Boisson-Dupuis
  • Philippe Langella
  • Jane Eyre Gabriel
  • François Lefèvre
  • Emmanuel Lemichez
  • Aziz El-Amraoui
  • Christine Petit

Detail Information

Publications22

  1. doi request reprint Animal models of Listeria infection
    Didier Cabanes
    Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular IBMC, Universidade do Porto, Portugal
    Curr Protoc Microbiol . 2008
    ..Although mice and guinea pigs can be infected with Listeria by a variety of routes, the intragastric route is the most relevant to the human foodborne listeriosis...
  2. doi request reprint LapB, a novel Listeria monocytogenes LPXTG surface adhesin, required for entry into eukaryotic cells and virulence
    Olga Reis
    Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
    J Infect Dis 202:551-62. 2010
    ..Our results highlight LapB as a new L. monocytogenes virulence adhesin with a function that is supported by its unique N-terminal domain through the probable interaction with a cellular receptor...
  3. ncbi request reprint In Vivo Transcriptional Profiling of Listeria monocytogenes and Mutagenesis Identify New Virulence Factors Involved in Infection
    Ana Camejo
    IBMC Instituto de Biologia Molecular e Celular, Group of Molecular Microbiology, Universidade do Porto, Oporto, Portugal
    PLoS Pathog 5:e1000449. 2009
    ..monocytogenes virulence factors, including an LPXTG surface protein, suggesting a role for S-layer glycoproteins and for cadmium efflux system in Listeria virulence...
  4. doi request reprint The arsenal of virulence factors deployed by Listeria monocytogenes to promote its cell infection cycle
    Ana Camejo
    Group of Molecular Microbiology, IBMC Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
    Virulence 2:379-94. 2011
    ..In this review, we summarize the current knowledge on nearly 50 molecules deployed by L. monocytogenes to promote its cell infection cycle...
  5. doi request reprint Extraction of cell wall-bound teichoic acids and surface proteins from Listeria monocytogenes
    Filipe Carvalho
    Group of Molecular Microbiology, Institute for Molecular and Cell Biology, Porto, Portugal
    Methods Mol Biol 966:289-308. 2013
    ..In this chapter, we describe methods for the extraction and analysis of (i) WTAs, (ii) covalently, and (iii) non-covalently cell wall-bound surface proteins from the Gram-positive pathogen Listeria monocytogenes...
  6. ncbi request reprint Listeria monocytogenes encodes a functional ESX-1 secretion system whose expression is detrimental to in vivo infection
    Jorge Pinheiro
    a Instituto de Investigação e Inovação em Saúde i3S, Universidade do Porto, Porto, Portugal
    Virulence . 2016
    ..Surprisingly, we found that the EssC-dependent secretion of EsxA has a detrimental effect on L. monocytogenes in vivo infection...
  7. pmc Listeria monocytogenes triggers the cell surface expression of Gp96 protein and interacts with its N terminus to support cellular infection
    Mariana Martins
    Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Universidade do Porto, 4150 180 Porto, Portugal
    J Biol Chem 287:43083-93. 2012
    ..Our findings unravel the Listeria-induced surface expression of Gp96 and the topology of its insertion on the plasma membrane and improve our knowledge on the Vip-Gp96 interaction during Listeria infection...
  8. pmc L-Rhamnosylation of Listeria monocytogenes Wall Teichoic Acids Promotes Resistance to Antimicrobial Peptides by Delaying Interaction with the Membrane
    Filipe Carvalho
    Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Porto, Portugal Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal
    PLoS Pathog 11:e1004919. 2015
    ..Strikingly, we reveal a key contribution of WTA L-rhamnosylation for L. monocytogenes virulence in a mouse model of infection. ..
  9. pmc Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection
    Maria Teresa Almeida
    From the Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200 Porto, Portugal, the Group of Molecular Microbiology, Instituto de Biologia Molecular e Celular, Universidade do Porto, 4150 180 Porto, Portugal, the Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050 313 Porto, Portugal
    J Biol Chem 290:8383-95. 2015
    ..monocytogenes, and this is dependent on the phosphorylation of Tyr-158. Our data suggest a novel mechanism of regulation of NMHC-IIA activity relying on the phosphorylation of Tyr-158 by Src. ..
  10. pmc Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins
    Francisco Sarmento Mesquita
    I3S Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
    EMBO Rep . 2016
    ..Finally, we validate the association between Gp96 and NMHCIIA in vivo and show that Gp96 is required to protect hosts from LLO-dependent killing...
  11. pmc In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection
    Ana Camejo
    IBMC, Instituto de Biologia Molecular e Celular, Group of Molecular Microbiology, Universidade do Porto, Porto, Portugal
    PLoS Pathog 5:e1000449. 2009
    ..monocytogenes virulence factors, including an LPXTG surface protein, suggesting a role for S-layer glycoproteins and for cadmium efflux system in Listeria virulence...
  12. pmc How Listeria monocytogenes organizes its surface for virulence
    Filipe Carvalho
    Group of Molecular Microbiology, Unit of Infection and Immunity, Instituto de Biologia Molecular e Celular, University of Porto Porto, Portugal
    Front Cell Infect Microbiol 4:48. 2014
    ..monocytogenes to organize its surface for virulence, with special focus on those proteins that work "behind the frontline", either supporting virulence effectors or ensuring the survival of the bacterium within its host. ..
  13. pmc Listeria monocytogenes induces host DNA damage and delays the host cell cycle to promote infection
    Elsa Leitão
    Group of Molecular Microbiology, Infection and Immunity IBMC Instituto de Biologia Molecular e Celular Universidade do Porto Porto, Portugal
    Cell Cycle 13:928-40. 2014
    ..We propose that host DNA replication disturbed by Lm infection culminates in DNA strand breaks, triggering DNA damage/replication responses, and ensuring a cell cycle delay that favors Lm propagation. ..
  14. ncbi request reprint Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis
    Olivier Dussurget
    Unité des Interactions Bactéries Cellules, Institut Pasteur, Paris, France
    Mol Microbiol 45:1095-106. 2002
    ..Taken together, these results demonstrate that BSH is a novel PrfA-regulated L. monocytogenes virulence factor involved in the intestinal and hepatic phases of listeriosis...
  15. pmc LPXTG protein InlJ, a newly identified internalin involved in Listeria monocytogenes virulence
    Christophe Sabet
    Unité des Interactions Bactéries Cellules, Institut Pasteur, INSERM U604, INRA USC2020, Paris, France
    Infect Immun 73:6912-22. 2005
    ..In conclusion, this postgenomic approach identified InlJ as a new virulence factor among the proteins belonging to the internalin family in L. monocytogenes...
  16. ncbi request reprint Auto, a surface associated autolysin of Listeria monocytogenes required for entry into eukaryotic cells and virulence
    Didier Cabanes
    Unité des Interactions Bactéries Cellules, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 51:1601-14. 2004
    ..During infection, the autolytic activity of Auto may also be critical. Auto appears thus as a novel type of L. monocytogenes virulence factor...
  17. ncbi request reprint Unconventional myosin VIIa and vezatin, two proteins crucial for Listeria entry into epithelial cells
    Sandra Sousa
    Unité des Interactions Bactéries Cellules, Institut Pasteur, 25 28 Rue du Dr Roux, 75724 Paris Cedex 15, France
    J Cell Sci 117:2121-30. 2004
    ..These results provide the first evidence for the role of an unconventional myosin in bacterial internalization and a novel example of the exploitation of mammalian proteins, by a pathogen, to establish a successful infection...
  18. ncbi request reprint Src, cortactin and Arp2/3 complex are required for E-cadherin-mediated internalization of Listeria into cells
    Sandra Sousa
    Institut Pasteur, Unité des Interactions Bactéries Cellules Inserm, U604 and INRA, USC2020, Paris F 75015, France
    Cell Microbiol 9:2629-43. 2007
    ..Together, these data suggest a model in which Src tyrosine kinase and Rac1 promote recruitment of cortactin and activation of Arp2/3 at Listeria entry site, mimicking events that occur during adherens junction formation...
  19. ncbi request reprint Internalin-expressing Lactococcus lactis is able to invade small intestine of guinea pigs and deliver DNA into mammalian epithelial cells
    Valeria Dellaretti Guimarães
    Unité de Recherches Laitières et de Génétique Appliquée, Institut National de la Recherche Agronomique, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
    Microbes Infect 7:836-44. 2005
    ..The L. lactis inlA+ strain will be a useful bacterial vector for the development of new live oral DNA vaccines. It also constitutes an interesting new model to study the role of internalin in bacterial localization in the animal host...
  20. pmc Gp96 is a receptor for a novel Listeria monocytogenes virulence factor, Vip, a surface protein
    Didier Cabanes
    Unité des Interactions Bactéries Cellules Institut Pasteur, INSERM U604, INRA USC 2020, Paris, France
    EMBO J 24:2827-38. 2005
    ..Vip thus appears as a new virulence factor exploiting Gp96 as a receptor for cell invasion and/or signalling events that may interfere with the host immune response in the course of the infection...
  21. ncbi request reprint ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasion
    Sandra Sousa
    Unité des Interactions Bactéries Cellules Institut Pasteur, INSERM U604, INRA USC2020, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Nat Cell Biol 7:954-60. 2005
    ..monocytogenes entry. Altogether, our results show that ARHGAP10 is a new component of cell-cell junctions that controls alpha-catenin recruitment and has a key role during L. monocytogenes uptake...
  22. ncbi request reprint Surface proteins and the pathogenic potential of Listeria monocytogenes
    Didier Cabanes
    Unité des Interactions Bactéries Cellules, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    Trends Microbiol 10:238-45. 2002
    ..We describe these families and discuss their putative implications for host-pathogen interactions...