- Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42Soren Prag
Richard Dimbleby Department of Cancer Research, King s College London, Guy s Medical School Campus, London SE1 1UL, United Kingdom
Mol Biol Cell 18:2935-48. 2007..Together these data suggest a mechanism whereby precise spatial guanine nucleotide exchange of Cdc42 by Dbl is dependent on functional ERM proteins and is important for directional cell migration...
- Novel role of the muskelin-RanBP9 complex as a nucleocytoplasmic mediator of cell morphology regulationManojkumar Valiyaveettil
Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
J Cell Biol 182:727-39. 2008..Knockdown of RanBP9 resulted in equivalent morphological alterations. These novel findings identify a role for muskelin-RanBP9 complex in pathways that integrate cell morphology regulation and nucleocytoplasmic communication...
- Fascins, and their roles in cell structure and functionNina Kureishy
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London
Bioessays 24:350-61. 2002..The supplementary material referred to in this section can be found at http://www.interscience.wiley.com/jpages/0265-9247/suppmat/2002/v24.350.html..
- Molecular analysis of muskelin identifies a conserved discoidin-like domain that contributes to protein self-associationSoren Prag
Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Biochem J 381:547-59. 2004..We obtained evidence for cis- and trans-interactions between the two domains. These studies provide evidence that muskelin self-associates through a head-to-tail mechanism involving the discoidin-like domain...