Piotr Ponikowski

Summary

Publications

  1. ncbi request reprint Chronic heart failure. The relationship between increased activity of skeletal muscle ergoreceptors and reduced exercise tolerance
    Agnieszka Kaczmarek
    Department of Cardiology, Military Hospital, Wrocław, Poland
    Kardiol Pol 60:322-32; discussion 333-4. 2004
  2. ncbi request reprint Excessive ventilation during early phase of exercise: a new predictor of poor long-term outcome in patients with chronic heart failure
    Ewa A Jankowska
    Cardiology Department, Military Hospital, Weigla 5, 50 981 Wroclaw, Poland
    Eur J Heart Fail 9:1024-31. 2007
  3. doi request reprint Pathogenesis and clinical presentation of acute heart failure
    Piotr Ponikowski
    Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland Centre for Heart Diseases, Military Hospital, Wroclaw, Poland Electronic address
    Rev Esp Cardiol (Engl Ed) 68:331-7. 2015
  4. pmc Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency†
    Piotr Ponikowski
    Department of Heart Diseases, Medical University, Wroclaw, Poland Department of Cardiology, Center for Heart Diseases, Clinical Military Hospital, Weigla 5 53 114, Wroclaw, Poland
    Eur Heart J 36:657-68. 2015
  5. pmc RHYTHM-AF: design of an international registry on cardioversion of atrial fibrillation and characteristics of participating centers
    Harry J G M Crijns
    Maastricht University Medical Center, Maastricht, Netherlands
    BMC Cardiovasc Disord 12:85. 2012
  6. pmc Transvenous phrenic nerve stimulation for the treatment of central sleep apnoea in heart failure
    Piotr Ponikowski
    4th Military Hospital, Wroclaw, Poland
    Eur Heart J 33:889-94. 2012
  7. doi request reprint Haemodynamic effects of rolofylline in the treatment of patients with heart failure and impaired renal function
    Piotr Ponikowski
    Department of Heart Diseases, Medical University, Clinical Military Hospital, Weigla 5, Wroclaw, Poland
    Eur J Heart Fail 12:1238-46. 2010
  8. doi request reprint Cardiorenal syndromes--recommendations from clinical practice guidelines: the cardiologist's view
    Piotr Ponikowski
    Cardiac Department, Faculty of Public Health, Medical University, Military Hospital, Wroclaw, Poland
    Contrib Nephrol 165:145-52. 2010
  9. doi request reprint Circulating testosterone and estradiol, autonomic balance and baroreflex sensitivity in middle-aged and elderly men with heart failure
    Agnieszka Rydlewska
    Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Aging Male 16:58-66. 2013
  10. doi request reprint Iron deficiency predicts impaired exercise capacity in patients with systolic chronic heart failure
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    J Card Fail 17:899-906. 2011

Detail Information

Publications74

  1. ncbi request reprint Chronic heart failure. The relationship between increased activity of skeletal muscle ergoreceptors and reduced exercise tolerance
    Agnieszka Kaczmarek
    Department of Cardiology, Military Hospital, Wrocław, Poland
    Kardiol Pol 60:322-32; discussion 333-4. 2004
    ..In chronic heart failure (CHF), skeletal muscle abnormalities may lead to the overactivation of ergoreceptors which in turn may cause sympathetic overactivation and increased ventilatory response to exercise...
  2. ncbi request reprint Excessive ventilation during early phase of exercise: a new predictor of poor long-term outcome in patients with chronic heart failure
    Ewa A Jankowska
    Cardiology Department, Military Hospital, Weigla 5, 50 981 Wroclaw, Poland
    Eur J Heart Fail 9:1024-31. 2007
    ..Whether ventilatory response to early phase of exercise is useful for risk stratification in CHF is unknown...
  3. doi request reprint Pathogenesis and clinical presentation of acute heart failure
    Piotr Ponikowski
    Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland Centre for Heart Diseases, Military Hospital, Wroclaw, Poland Electronic address
    Rev Esp Cardiol (Engl Ed) 68:331-7. 2015
    ....
  4. pmc Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency†
    Piotr Ponikowski
    Department of Heart Diseases, Medical University, Wroclaw, Poland Department of Cardiology, Center for Heart Diseases, Clinical Military Hospital, Weigla 5 53 114, Wroclaw, Poland
    Eur Heart J 36:657-68. 2015
    ..The aim of this study was to evaluate the benefits and safety of long-term i.v. iron therapy in iron-deficient patients with heart failure (HF)...
  5. pmc RHYTHM-AF: design of an international registry on cardioversion of atrial fibrillation and characteristics of participating centers
    Harry J G M Crijns
    Maastricht University Medical Center, Maastricht, Netherlands
    BMC Cardiovasc Disord 12:85. 2012
    ..There are limited data on the variation in treatment practice patterns across different countries, healthcare settings and the associated health outcomes...
  6. pmc Transvenous phrenic nerve stimulation for the treatment of central sleep apnoea in heart failure
    Piotr Ponikowski
    4th Military Hospital, Wroclaw, Poland
    Eur Heart J 33:889-94. 2012
    ..We conducted a prospective, non-randomized, acute study to determine the feasibility of using unilateral transvenous phrenic nerve stimulation for the treatment of CSA in heart failure patients...
  7. doi request reprint Haemodynamic effects of rolofylline in the treatment of patients with heart failure and impaired renal function
    Piotr Ponikowski
    Department of Heart Diseases, Medical University, Clinical Military Hospital, Weigla 5, Wroclaw, Poland
    Eur J Heart Fail 12:1238-46. 2010
    ..The direct effects of adenosine A1 receptor antagonists on haemodynamic parameters in patients with acute heart failure (HF) remain largely unknown...
  8. doi request reprint Cardiorenal syndromes--recommendations from clinical practice guidelines: the cardiologist's view
    Piotr Ponikowski
    Cardiac Department, Faculty of Public Health, Medical University, Military Hospital, Wroclaw, Poland
    Contrib Nephrol 165:145-52. 2010
    ..Future research trials in heart failure should include patients with renal insufficiency to allow better understanding of the impact of the current treatments available in patients with cardiorenal syndromes...
  9. doi request reprint Circulating testosterone and estradiol, autonomic balance and baroreflex sensitivity in middle-aged and elderly men with heart failure
    Agnieszka Rydlewska
    Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Aging Male 16:58-66. 2013
    ..We investigated the relations between autonomic status, baroreflex sensitivity (BRS) and hormone status in men with mild systolic HF...
  10. doi request reprint Iron deficiency predicts impaired exercise capacity in patients with systolic chronic heart failure
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    J Card Fail 17:899-906. 2011
    ..Hence, iron deficiency (ID) is anticipated to limit exercise capacity. We investigated whether ID predicted exercise intolerance in patients with systolic chronic heart failure (CHF)...
  11. ncbi request reprint Could gonadal and adrenal androgen deficiencies contribute to the depressive symptoms in men with systolic heart failure?
    Katarzyna Kulej-Lyko
    a Centre for Heart Diseases, Military Hospital, Wroclaw, Poland
    Aging Male 19:221-230. 2016
    ..We investigated the link between hypogonadism and depression in accordance with age and concomitant diseases in men with systolic HF using the novel scale previously dedicated for elderly population...
  12. doi request reprint Deficiencies in circulating testosterone and dehydroepiandrosterone sulphate, and depression in men with systolic chronic heart failure
    Ewa A Jankowska
    Department of Heart Diseases, Faculty of Health Sciences, Wroclaw Medical University Military Hospital, Wroclaw, Poland
    Eur J Heart Fail 12:966-73. 2010
    ..Elderly men with androgen deficiencies are prone to develop late-onset depression. We investigated links between circulating androgens and depression, and their combined impact on outcome in men with chronic heart failure (CHF)...
  13. pmc Expression and complex formation of MMP9, MMP2, NGAL, and TIMP1 in porcine myocardium but not in skeletal muscles in male pigs with tachycardia-induced systolic heart failure
    Liliana Kiczak
    Regional Specialist Hospital in Wroclaw, Research and Development Centre, Wroclaw, Poland
    Biomed Res Int 2013:283856. 2013
    ..In skeletal muscles from both diseased and healthy animals, in nonreducing and nondenaturing conditions, we found no HMW complexes, and proteolytic activity was associated with the presence of 72 and 68 kDa bands (proMMP2 and MMP2)...
  14. doi request reprint Changes in autonomic balance in patients with decompensated chronic heart failure
    Agnieszka Rydlewska
    Centre for Heart Diseases, Military Hospital, Weigla 5, Wroclaw, Poland
    Clin Auton Res 21:47-54. 2011
    ..In chronic heart failure (CHF) episodes of decompensation may be linked to derangements within cardiovascular reflex control. We investigated changes in autonomic tone in patients with decompensated CHF...
  15. doi request reprint Gonadal and adrenal androgen deficiencies as independent predictors of increased cardiovascular mortality in men with type II diabetes mellitus and stable coronary artery disease
    Beata Ponikowska
    Department of Physiology, Wroclaw Medical University, and Centre for Heart Disease, Cardiology Department, Military Hospital, Wroclaw, Poland
    Int J Cardiol 143:343-8. 2010
    ..Age-related decline in circulating androgens in men is associated with poor cardiovascular (CV) outcome. Men with type II diabetes mellitus (DM) are prone to develop androgen deficiency...
  16. doi request reprint Iron deficiency: an ominous sign in patients with systolic chronic heart failure
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Medical University, Centre for Heart Diseases, Military Hospital, ul Weigla 5, Wroclaw, Poland
    Eur Heart J 31:1872-80. 2010
    ..We sought to examine the relationship between ID and survival in patients with systolic CHF...
  17. doi request reprint Anabolic deficiencies in men with systolic heart failure: do co-morbidities and therapies really contribute significantly?
    Elżbieta Kalicińska
    Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Aging Male 16:123-31. 2013
    ..It remains unclear whether the deranged metabolism of these hormones is the pathophysiological element of HF itself or is the consequence of co-morbidities or/and treatment in HF...
  18. doi request reprint Changes in parasympathetic system in medulla oblongata in male pigs in the course of tachycardia-induced cardiomyopathy
    Alicja Tomaszek
    Regional Specialist Hospital in Wroclaw, Research and Development Centre, Wroclaw, Poland Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Auton Neurosci 177:253-9. 2013
    ..7 nicotinic acetylcholine receptor (α7nAChR) and enzymes metabolizing acetylcholine (acetylcholinesterase, AChE, choline acetyltransferase, ChAT) in medulla oblongata (MO) of male pigs with chronic tachycardia-induced cardiomyopathy...
  19. ncbi request reprint Abnormal indices of autonomic function are no longer predictors of poor outcome in diabetic patients without neuropathy but with coexisting coronary artery disease who receive optimal pharmacological therapy
    Beata Ponikowska
    Department of Physiology, Medical University, Wroclaw, Poland
    Kardiol Pol 67:1325-32. 2009
    ..Cardiovascular autonomic neuropathy (CAN) is a complication of diabetes mellitus (DM) and has been regarded as a parameter associated with a poor outcome...
  20. ncbi request reprint Determinants of physical fitness in males with systolic heart failure
    Kinga Wegrzynowska-Teodorczyk
    Department of Physiotherapy in Conservative and Interventional Medicine, The Faculty of Physiotherapy, University School of Physical Education, and Heart Diseases Center, IV Clinical Military Hospital, Wroclaw, Poland
    Kardiol Pol 68:146-54. 2010
    ..So far no study on the impact of HF on physical fitness in men, regardless of disease severity, has been reported...
  21. doi request reprint Reduction in circulating testosterone relates to exercise capacity in men with chronic heart failure
    Ewa A Jankowska
    Cardiology Department, Military Hospital, Wroclaw, Poland
    J Card Fail 15:442-50. 2009
    ..Anabolic hormones (testosterone, dehydroepiandrosterone sulfate, insulin-like growth factor 1 [IGF1]) contribute to exercise capacity in healthy men. This issue remains unclear in CHF...
  22. doi request reprint Bone mineral status and bone loss over time in men with chronic systolic heart failure and their clinical and hormonal determinants
    Ewa A Jankowska
    Cardiology Department, Military Hospital, ul Weigla 5, 50 981 Wroclaw, Poland
    Eur J Heart Fail 11:28-38. 2009
    ..Bone status has not been comprehensively studied in chronic heart failure (CHF). In CHF men, we evaluated bone status, bone loss over time, and their clinical and hormonal determinants...
  23. pmc Effects of selective carotid body stimulation with adenosine in conscious humans
    Stanislaw Tubek
    Department of Cardiology, Centre for Heart Diseases, 4th Military Hospital, Wroclaw, Poland
    J Physiol 594:6225-6240. 2016
    ..Intra-carotid adenosine administration may provide a novel method for perioperative assessment of the effectiveness of carotid body ablation, which has been recently proposed as a treatment strategy for sympathetically-mediated diseases...
  24. ncbi request reprint Liver function tests in patients with acute heart failure
    Jan Biegus
    Centre for Heart Diseases, 4th Military Hospital, Wrocław, Poland
    Pol Arch Med Wewn 122:471-9. 2012
    ..Acute heart failure (AHF) is associated with multiorgan dysfunction, which may unfavorably affect prognosis...
  25. pmc Iron status in patients with chronic heart failure
    Ewa A Jankowska
    Laboratory for Applied Research of Cardiovascular System, Department of Heart Diseases, Faculty of Health Sciences, Wroclaw Medical University, ul Weigla 5, 50 981 Wroclaw, Poland
    Eur Heart J 34:827-34. 2013
    ..We investigated iron status in a broad spectrum of patients with systolic HF in order to determine the changes in iron status in parallel with disease progression, and to associate iron status with long-term prognosis...
  26. doi request reprint Circulating estradiol and mortality in men with systolic chronic heart failure
    Ewa A Jankowska
    Center for Heart Disease, Cardiology Department, Military Hospital, ul Weigla 5, 50 981 Wroclaw, Poland
    JAMA 301:1892-901. 2009
    ..Estrogens are formed by the aromatization of androgens; therefore, abnormal estrogen metabolism would be anticipated in HF...
  27. doi request reprint Central Chemoreceptor Sensitivity Is Not Enhanced in Contemporary Patients With Chronic Systolic Heart Failure Receiving Optimal Treatment
    Bartłomiej Paleczny
    Department of Physiology, Wroclaw Medical University, Wroclaw, Poland Department of Cardiology, Centre for Heart Diseases, 4th Military Hospital, Wroclaw, Poland Electronic address
    J Card Fail 23:83-87. 2017
    ..Clinical and prognostic consequences of enhanced central chemosensitivity in the contemporary optimally treated patients with chronic heart failure (CHF) are unknown...
  28. doi request reprint Effects of intravenous iron therapy in iron-deficient patients with systolic heart failure: a meta-analysis of randomized controlled trials
    Ewa A Jankowska
    Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Eur J Heart Fail 18:786-95. 2016
    ..The aim of this study was to assess the net clinical and prognostic effects of intravenous (i.v.) iron therapy in patients with systolic heart failure (HF) and iron deficiency (ID)...
  29. doi request reprint Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure
    Jozine M Ter Maaten
    From the Departments of Cardiology J M t M, M A E V, K D, D J v V, P v d M, H L H, A A V and Epidemiology H L H, University of Groningen, University Medical Center Groningen, The Netherlands University of Hull, Kingston upon Hull, United Kingdom J G C Brigham and Women s Hospital, Boston, MA M M G University of Brescia, Italy M M Inova Heart and Vascular Institute, Falls Church, VA C M O C University of California at San Francisco, San Francisco Veterans Affairs Medical Center, CA J R T Medical University, Clinical Military Hospital, Wroclaw, Poland P P Merck Research Laboratories, Rahway, NJ D M B Momentum Research, Durham, NC G C, B D University of Iowa Carver College of Medicine Cardiovascular Research Center Iowa City, IA H S, M G and Center for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, Chicago, IL H S, M G
    Circ Heart Fail 9:. 2016
    ..This study examines the value of combining diuretic response and hemoconcentration to better predict patients at low risk for rehospitalization after admission for acute HF...
  30. doi request reprint Carotid body resection for sympathetic modulation in systolic heart failure: results from first-in-man study
    Piotr Niewiński
    Department of Cardiology, Centre for Heart Disease, 4th Military Hospital, Wroclaw, Poland
    Eur J Heart Fail . 2016
    ..We investigated whether surgical resection of CBs in these patients can be performed safely to decrease sympathetic tone...
  31. ncbi request reprint Andropausal syndrome in men with systolic heart failure
    Michał Tkaczyszyn
    Students Scientific Association, Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wrocław, Poland
    Pol Arch Med Wewn 123:156-69. 2013
    ..Andropausal syndrome (AS) is an element of male aging, being associated with the age-related decline in circulating androgens...
  32. ncbi request reprint Comparison of drug-eluting stents to bare-metal stents in ST-elevation myocardial infarction in long-term follow-up
    Piotr Kubler
    Department of Cardiology, Clinical Military Hospital, Wroclaw, Poland
    Kardiol Pol 71:25-31. 2013
    ..Recent data from "real world" registries and some randomised trials concerning the safety and efficacy of drug-eluting stents (DES) in patients with acute ST-elevation myocardial infarction (STEMI) are equivocal...
  33. ncbi request reprint Lack of decrease in plasma N-terminal pro-brain natriuretic peptide identifies acute heart failure patients with very poor outcome
    Piotr Kubler
    Cardiology Department, Military Hospital, Wroclaw, Poland
    Int J Cardiol 129:373-8. 2008
    ..We investigated whether a lack of significant decrease in plasma levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) during hospital stay can identify patients at high risk of poor outcome...
  34. ncbi request reprint Clinical characteristics and predictors of in-hospital mortality in 270 consecutive patients hospitalised due to acute heart failure in a single cardiology centre during one year
    Jan Biegus
    Cardiology Department, 4th Military Hospital, Wroclaw, Poland
    Kardiol Pol 69:997-1005. 2011
    ..Acute heart failure (HF) is an emerging problem in clinical practice, associated with high in-hospital mortality and a high short-term readmission rate...
  35. doi request reprint Late Cardiac Tamponade as a Result of Parietal Pericardium Erosion
    Stanislaw Tubek
    Department of Cardiology, 4 th Military Hospital, Wroclaw, Poland Department of Heart Disease, Faculty of Health Sciences, Medical University in Wroclaw, Wroclaw, Poland Electronic address
    Ann Thorac Surg 100:715-7. 2015
    ..Conservative management in the described clinical scenario could be fatal, thus awareness of this pathomechanism of tamponade is critical. ..
  36. doi request reprint Dissociation between blood pressure and heart rate response to hypoxia after bilateral carotid body removal in men with systolic heart failure
    Piotr Niewiński
    Department of Cardiology, Centre for Heart Disease, 4th Military Hospital, 4 Wojskowy Szpital Kliniczny, ul Weigla 5, Wroclaw 50 981, Poland
    Exp Physiol 99:552-61. 2014
    ..The significant reduction of the blood pressure response to hypoxia after CBR suggests a decrease in sympathetic tone, which is of particular clinical relevance in congestive heart failure. ..
  37. doi request reprint Clinical predictors and hemodynamic consequences of elevated peripheral chemosensitivity in optimally treated men with chronic systolic heart failure
    Piotr Niewiński
    Department of Cardiology, Center for Heart Disease, 4th Military Hospital, Wroclaw, Poland
    J Card Fail 19:408-15. 2013
    ..This study characterizes prevalence and clinical predictors of this phenomenon in optimally managed male CHF patients, and seeks to describe the hemodynamic consequences of chemoreceptor hypersensitivity...
  38. pmc Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Medical University, ul Weigla 5, 50 981 Wroclaw, Poland
    Eur Heart J 34:816-29. 2013
    ..v. iron on the functional status, quality of life, and exercise capacity in HF patients. It is hypothesized that i.v. iron supplementation may become a novel therapy in HF patients with iron deficiency...
  39. doi request reprint Comparison of invasive and non-invasive measurements of haemodynamic parameters in patients with advanced heart failure
    Mateusz Sokolski
    Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    J Cardiovasc Med (Hagerstown) 12:773-8. 2011
    ..The aim of the study was to estimate the concordance between invasive and non-invasive measurements of haemodynamic parameters in patients with advanced heart failure...
  40. pmc Identification of chronic heart failure patients with a high 12-month mortality risk using biomarkers including plasma C-terminal pro-endothelin-1
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Military Hospital, Wroclaw, Poland
    PLoS ONE 6:e14506. 2011
    ....
  41. ncbi request reprint Activation of the NF-kappaB system in peripheral blood leukocytes from patients with chronic heart failure
    Ewa A Jankowska
    Cardiology Department, Military Hospital, ul Weigla 5, 50 981 Wroclaw, Poland
    Eur J Heart Fail 7:984-90. 2005
    ..In vitro experiments were used to elucidate the role of lipopolysaccharide (LPS) as a stimulus for the NF-kappaB system in PBL...
  42. ncbi request reprint Hyperuricaemia predicts poor outcome in patients with mild to moderate chronic heart failure
    Ewa A Jankowska
    Cardiology Department, Military Hospital, ul Weigla 5, 50 981 Wroclaw, Poland
    Int J Cardiol 115:151-5. 2007
    ..This study investigates whether hyperuricaemia (defined as serum UA level > or = 6.5 mg/dL) extends its prognostic value on population with less advanced CHF...
  43. doi request reprint Urinary levels of novel kidney biomarkers and risk of true worsening renal function and mortality in patients with acute heart failure
    Mateusz Sokolski
    Wroclaw Medical University, Department of Heart Diseases, Wroclaw, Poland
    Eur J Heart Fail . 2017
    ..We evaluated the usefulness of serial assessment of urinary levels of neutrophil gelatinase-associated lipocalin (uNGAL), kidney injury molecule-1 (uKIM-1), and cystatin C (uCysC) for prediction of 'true WRF'...
  44. doi request reprint Both iron excess and iron depletion impair viability of rat H9C2 cardiomyocytes and L6G8C5 myocytes
    Monika Kasztura
    Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Kardiol Pol . 2016
    ..There is some clinical evidence demonstrating that iron deficiency has serious negative prognostic consequence in heart failure (HF) patients and its correction brought clinical benefit...
  45. doi request reprint Impaired hepato-renal function defined by the MELD XI score as prognosticator in acute heart failure
    Jan Biegus
    Centre for Heart Diseases, Military Hospital, Wroclaw, Poland
    Eur J Heart Fail 18:1518-1521. 2016
    ..The aim of this study was to assess the prognostic utility of the MELD score in patients with AHF...
  46. doi request reprint Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure
    Jozine M Ter Maaten
    From the University Medical Center, University of Groningen, The Netherlands J M t M, K D, H L H, D J v V, A A V Program of Applied Translational Research, Yale University School of Medicine, New Haven, CT J M t M, J S H, J M T Brigham and Women s Hospital, Boston, MA M M G University of Brescia, Italy M M Inova Heart and Vascular Institute, Falls Church, VA C M O University of California at San Francisco and San Francisco Veterans Affairs Medical Center J R T Medical University, Clinical Military Hospital, Wroclaw, Poland P P Momentum Research, Durham, NC G C, B D University of Hull, Kingston upon Hull, United Kingdom J G C Merck Research Laboratories, Rahway, NJ D M B Department of Internal Medicine, Yale University School of Medicine, New Haven, CT J M T
    Circ Heart Fail 9:. 2016
    ..AHF therapies, such as diuretics, alter chloride homeostasis. We studied the association between (changes in) chloride levels and diuretic responsiveness, decongestion, and mortality in patients with AHF...
  47. doi request reprint Nordic Walking May Safely Increase the Intensity of Exercise Training in Healthy Subjects and in Patients with Chronic Heart Failure
    Andrzej Lejczak
    Department of Cardiac Rehabilitation, Center for Heart Diseases, 4th Military Hospital, Wrocław, Poland Department of Physiotherapy, University School of Physical Education, Wrocław, Poland
    Adv Clin Exp Med 25:145-9. 2016
    ....
  48. doi request reprint Iron deficiency defined as depleted iron stores accompanied by unmet cellular iron requirements identifies patients at the highest risk of death after an episode of acute heart failure
    Ewa A Jankowska
    Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wrocław Medical University, Wrocław, Poland Cardiology Department, Centre for Heart Diseases, Military Hospital, ul Weigla 5, Wrocław 50 981, Poland
    Eur Heart J 35:2468-76. 2014
    ..Iron is a key micronutrient for homoeostasis maintenance. We hypothesized that iron deficiency (ID) defined as depleted iron stores accompanied by unmet cellular iron requirements would in this setting predict the poor outcome...
  49. pmc Normal electrocardiographic and echocardiographic (M-mode and two-dimensional) values in Polish Landrace pigs
    Urszula Paslawska
    Regional Specialist Hospital in Wroclaw, Research and Development Centre, Kamienskiego Street 73a, Wroclaw, 51 124, Poland
    Acta Vet Scand 56:54. 2014
    ..All electrocardiographic and echocardiographic measurements in all swine were done under general anaesthesia...
  50. doi request reprint Design of the RELAXin in acute heart failure study
    Piotr Ponikowski
    Department of Heart Diseases, Medical University, Military Hospital, Wroclaw, Poland
    Am Heart J 163:149-55.e1. 2012
    ..The RELAX-AHF-1 study will evaluate the effect of RLX030 (recombinant form of human relaxin 2) on symptom relief and clinical outcomes in patients with AHF...
  51. doi request reprint Carotid body removal for treatment of chronic systolic heart failure
    Piotr Niewiński
    Department of Cardiology, Centre for Heart Disease, 4th Military Hospital, Wroclaw, Poland Electronic address
    Int J Cardiol 168:2506-9. 2013
    ..Augmented reflex response from peripheral chemoreceptors characterises chronic heart failure (CHF), contributes to autonomic imbalance and exercise intolerance and predicts poor outcome...
  52. ncbi request reprint Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial
    Piotr Ponikowski
    Cardiac Department, Military Hospital, Wroclaw, Poland
    J Am Coll Cardiol 49:753-62. 2007
    ..This study sought to investigate whether darbepoetin alfa, an erythropoiesis-stimulating protein (ESP), improves exercise capacity in patients with symptomatic chronic heart failure (CHF) and anemia...
  53. ncbi request reprint Autonomic imbalance and immune activation in chronic heart failure - pathophysiological links
    Ewa A Jankowska
    Cardiology Department, Military Hospital, Wroclaw, Poland
    Cardiovasc Res 70:434-45. 2006
    ..Diminished cholinergic signalling (mainly nicotinergic) activates inflammation and stimulates immune response. These two phenomena predict prognosis and represent therapeutic targets in the syndrome of CHF...
  54. ncbi request reprint Anabolic deficiency in men with chronic heart failure: prevalence and detrimental impact on survival
    Ewa A Jankowska
    Cardiology Department, Military Hospital, ul Weigla 5, 50 981 Wroclaw, Poland
    Circulation 114:1829-37. 2006
    ....
  55. ncbi request reprint Chronotropic response during exercise and recovery in men with mild systolic chronic heart failure
    Bartosz Krakowiak
    Heart Diseases Center, 4th Clinical Military Hospital, Department of Heart Diseases, Medical University, Wroclaw, Poland
    Kardiol Pol 68:1323-30. 2010
    ..This issue has been poorly examined in patients with chronic heart failure (CHF), particularly in the early stages of this syndrome...
  56. doi request reprint Could an analysis of mean corpuscular volume help to improve a risk stratification in non-anemic patients with acute myocardial infarction?
    Paweł Franczuk
    Cardiology Department, Centre for Heart Diseases, 4th Military Hospital, Wroclaw, Poland Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Cardiol J . 2015
    ..The aim of the study was to estimate the prevalence of high mean corpuscular volume (MCV, defined as MCV >92 fL) and to establish its prognostic value in non-anemic patients with AMI...
  57. pmc Increased body fat is associated with potentiation of blood pressure response to hypoxia in healthy men: relations with insulin and leptin
    Bartłomiej Paleczny
    Department of Physiology, Wroclaw Medical University, ul Chałubińskiego 10, 50 368, Wroclaw, Poland
    Clin Auton Res 26:107-16. 2016
    ..However, human data on PChS in obesity are scarce. Therefore, we explored this issue in a sample of 41 healthy men aged 30-59 years, divided according to body fat percentage (fat %) into two groups: <25 and ≥25 %...
  58. doi request reprint Bone marrow iron depletion is common in patients with coronary artery disease
    Ewa A Jankowska
    Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland Centre for Heart Diseases, Military Hospital, Wroclaw, Poland Electronic address
    Int J Cardiol 182:517-22. 2015
    ..Accordingly, we investigated the relationship between blood tests for ID and iron stores in bone marrow aspirates, the diagnostic gold-standard for ID, in patients with stable coronary artery disease (CAD)...
  59. ncbi request reprint The 12-week progressive quadriceps resistance training improves muscle strength, exercise capacity and quality of life in patients with stable chronic heart failure
    Ewa A Jankowska
    Cardiology Department, Military Hospital, Wroclaw, Poland
    Int J Cardiol 130:36-43. 2008
    ..We investigated, whether in CHF selective resistance training without accompanying aerobic regime favourably affects muscle strength, muscle mass and improves exercise capacity...
  60. ncbi request reprint Borderline coronary lesions may lead to serious coronary events--long-term outcome in 65 conservatively treated patients
    Krzysztof Rzeczuch
    Department of Cardiology, 4th Military Hospital, Wrocław, Poland
    Kardiol Pol 63:50-6; discussion 57. 2005
    ..The choice of optimal therapy in a patient with borderline coronary lesion is difficult. The long-term outcome of conservatively treated patients has not yet been well defined...
  61. doi request reprint Influence of the availability of iron during hypoxia on the genes associated with apoptotic activity and local iron metabolism in rat H9C2 cardiomyocytes and L6G8C5 skeletal myocytes
    Magdalena Dziegala
    Students Scientific Organization, Department of Heart Diseases, Wrocław Medical University, 50 367 Wrocław, Poland
    Mol Med Rep 14:3969-77. 2016
    ..In myocytes, during hypoxia iron may act in a protective manner, since the level of atrophy is decreased in the iron‑salt‑treated cells. ..
  62. doi request reprint Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure
    Koen W Streng
    From the Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands K W S, J M t M, H L H, D J v V, A A V, P v d M National Heart and Lung Institute, Royal Brompton and Harefield Hospitals, Imperial College, London, United Kingdom J G C Inova Heart and Vascular Institute, Falls Church, VA C M O C Momentum Research, Durham, NC B A D University of Brescia, Italy M M Brigham and Women s Hospital, Boston, MA M M G University of California at San Francisco and San Francisco Veterans Affairs Medical Center J R T Medical University, Clinical Military Hospital, Wroclaw, Poland P P Merck Research Laboratories, Rahway, NJ D M B and University of Iowa Carver College of Medicine Cardiovascular Research Center H C D
    Circ Heart Fail 10:. 2017
    ..Whether this is true for other biomarkers is unknown. We investigated a wide range of biomarker profiles in acute heart failure across the body mass index (BMI) spectrum...
  63. doi request reprint Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study
    Jan Biegus
    Department of Heart Diseases, Medical University, Wroclaw, Poland
    Eur J Heart Fail 18:830-9. 2016
    ..We investigated the prevalence and clinical consequences of abnormal liver function tests (LFTs) in AHF patients enrolled in the PROTECT study...
  64. pmc Skeletal myopathy in patients with chronic heart failure: significance of anabolic-androgenic hormones
    Krystian Josiak
    Clinic for Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    J Cachexia Sarcopenia Muscle 5:287-96. 2014
    ....
  65. pmc Consequences of peripheral chemoreflex inhibition with low-dose dopamine in humans
    Piotr Niewiński
    Department of Cardiology, Centre for Heart Diseases, 4 Military Hospital, ul Weigla 5, 50 981, Wroclaw, Poland
    J Physiol 592:1295-308. 2014
    ..The ventilatory reaction to dopamine withdrawal constitutes a novel index of peripheral chemoreceptor function. ..
  66. doi request reprint Comparison of clinical profile and management of outpatients with heart failure with reduced left ventricular ejection fraction treated by general practitioners and cardiologists in contemporary Poland: the results from the DATA-HELP registry
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland Cardiology Department, Centre for Heart Diseases, Military Hospital, Wroclaw, Poland Electronic address
    Int J Cardiol 176:852-8. 2014
    ..We sought to determine and compare clinical profile and management of outpatients with heart failure with reduced ejection fraction (HFREF) treated by cardiologists and general practitioners (GPs) in Poland...
  67. pmc A randomized, double-blind, placebo-controlled, multicentre study to assess haemodynamic effects of serelaxin in patients with acute heart failure
    Piotr Ponikowski
    Department of Heart Diseases, Medical University, Military Hospital, Weigla 5, 50 981 Wroclaw, Poland
    Eur Heart J 35:431-41. 2014
    ..The aim of this study was to evaluate the haemodynamic effects of serelaxin (30 µg/kg/day 20-h infusion and 4-h post-infusion period) in patients with acute heart failure (AHF)...
  68. pmc Health locus of control and the sense of self-efficacy in patients with systolic heart failure: a pilot study
    Agnieszka Rydlewska
    Centre for Heart Diseases, Department of Cardiology, Military Hospital, Wroclaw, Poland Department of Heart Diseases, Wroclaw Medical University, Wroclaw Poland
    Patient Prefer Adherence 7:337-43. 2013
    ....
  69. doi request reprint Molecular changes in myocardium in the course of anemia or iron deficiency
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Medical University, Centre for Heart Diseases, Military Hospital, ul Weigla 5, Wroclaw 50 981, Poland
    Heart Fail Clin 6:295-304. 2010
    ..Most of the data come from experimental models. Further studies, in particular performed in clinical settings, are warranted...
  70. doi request reprint Heart failure classifications - guidelines
    Ewa A Jankowska
    Department of Heart Diseases, Wroclaw Medical University, and Centre for Heart Diseases, Military Hospital, Wroclaw, Poland
    Contrib Nephrol 164:11-23. 2010
    ..Classifications are based on the time course of the clinical presentation of heart failure, severity of symptoms and signs of heart failure, structural changes within the heart, predominant etiology and comorbidities...
  71. doi request reprint Sexual dimorphism in socioeconomic differences regarding the risk factors, symptomatology and management of patients with stable coronary artery disease in Poland
    Stanislaw Tubek
    Department of Cardiology, Center for Heart Diseases, 4th Military Hospital, Wroclaw, Poland Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
    Cardiol J 22:487-94. 2015
    ..The aim of the study was to investigate SES gradients regarding the risk factors, symptoms and management of patients with stable CAD in Poland, separately in men and women...
  72. doi request reprint Effect on mode of death of heart failure treatment started with bisoprolol followed by Enalapril, compared to the opposite order: results of the randomized CIBIS III trial
    Henry Krum
    Departments of Epidemiology and Preventive Medicine and Medicine, Monash University, Alfred Hospital, Melbourne, Australia Thoraxcenter, Department of Cardiology, University Hospital Groningen, The Netherlands UPMC AP HP INSERM CIC9304, Department of Pharmacology, Pitie Salpetriere Hospital, Paris, France Department of Cardiology, University of Pavia and Policlinico di Monza, Italy Department of Pharmacology and Therapeutics, Trinity Centre, St James Hospital, Dublin, Ireland Medizinische Klinik III, University of Cologne, Germany Medicine A, University Hospital Zurich, Switzerland Department of Heart Diseases, Medical University, Wroclaw, Poland Worldwide Clinical Trials, Nottingham, UK Merck KGaA, Darmstadt, Germany Service de Pharmacologie, Hopital Pitie Salpetriere, Paris, France Lund University and Heart Health Group, Malmo, Sweden
    Cardiovasc Ther 29:89-98. 2011
    ..Sudden death is particularly common in patients with early and/or mild/moderate CHF. β-Blockade may provide better protection against sudden death than ACE inhibition (ACEI) in this setting...
  73. pmc The impact of intravenous ferric carboxymaltose on renal function: an analysis of the FAIR-HF study
    Piotr Ponikowski
    Medical University, Wroclaw, Poland
    Eur J Heart Fail 17:329-39. 2015
    ..We investigated the effects of i.v. iron in iron-deficient CHF patients on renal function, and the efficacy and safety of this therapy in patients with renal dysfunction...
  74. doi request reprint Development of porcine model of chronic tachycardia-induced cardiomyopathy
    Urszula Paslawska
    Regional Specialist Hospital in Wroclaw, Research and Development Centre, Wroclaw, Poland
    Int J Cardiol 153:36-41. 2011
    ..There are few experimental models of heart failure (HF) in large animals, despite structural and functional similarities to human myocardium. We have developed a porcine model of chronic tachycardia-induced cardiomyopathy...