M Zembala

Summary

Country: Poland

Publications

  1. pmc Properties of monocytes generated from haematopoietic CD34(+) stem cells from bone marrow of colon cancer patients
    Malgorzata Stec
    Department of Clinical Immunology and Transplantation, Polish American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka Str 265, 30 663, Cracow, Poland
    Cancer Immunol Immunother 62:705-13. 2013
  2. ncbi request reprint Chemokine receptors and chemokine production by CD34+ stem cell-derived monocytes in response to cancer cells
    Malgorzata Stec
    Department of Clinical Immunology, Polish American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka Str 265, 30 663 Cracow, Poland
    Anticancer Res 32:4749-53. 2012
  3. pmc Biological activity of dendritic cells generated from cord blood CD34+ hematopoietic progenitors in IL-7- and IL-13-conditioned cultures
    Bozenna Mytar
    Department of Clinical Immunology, Polish American Institute of Pediatrics, Jagiellonian University Medical College, Cracow, Poland
    Arch Immunol Ther Exp (Warsz) 57:67-74. 2009
  4. ncbi request reprint Phenotypic changes of monocytes induced by HIV-1 gp120 molecule and its fragments
    M Zembala
    Department of Clinical Immunology, Jagiellonian University Medical School, Cracow, Poland
    Immunobiology 197:110-21. 1997
  5. ncbi request reprint Demonstration of iNOS-mRNA and iNOS in human monocytes stimulated with cancer cells in vitro
    M Siedlar
    Department of Clinical Immunology, Polish American Institute of Pediatrics, Krakow, Poland
    J Leukoc Biol 65:597-604. 1999
  6. pmc Three-color flow cytometry detection of intracellular cytokines in peripheral blood mononuclear cells: comparative analysis of phorbol myristate acetate-ionomycin and phytohemagglutinin stimulation
    J Baran
    Department of Clinical Immunology, Polish-American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka Str. 265, 30-663 Cracow, Poland
    Clin Diagn Lab Immunol 8:303-13. 2001
  7. pmc Induction of reactive oxygen intermediates in human monocytes by tumour cells and their role in spontaneous monocyte cytotoxicity
    B Mytar
    Department of Clinical Immunology, Polish American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka, Cracow, Poland
    Br J Cancer 79:737-43. 1999
  8. ncbi request reprint Involvement of protein kinases in signalling for nitric oxide (NO) and tumour necrosis factor alpha (TNF) production by monocytes stimulated with colorectal DeTa cancer cells: the lack of evidence for the role of TNF in the regulation of NO production
    M Siedlar
    Department of Clinical Immunology, Polish American Institute of Paediatrics, Jagiellonian University Medical Faculty, Cracow, Poland
    Immunol Lett 65:189-95. 1999
  9. doi request reprint Peripheral blood CD14high CD16+ monocytes are main producers of IL-10
    J Skrzeczynska-Moncznik
    Department of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland
    Scand J Immunol 67:152-9. 2008
  10. ncbi request reprint CD14+CD16+ monocytes in the course of sepsis in neonates and small children: monitoring and functional studies
    J Skrzeczynska
    Department of Immunology, Institute of Molecular Biology, Jagiellonian University, Medical College, Cracow, Poland
    Scand J Immunol 55:629-38. 2002

Collaborators

  • M Ernst
  • R Lauterbach
  • E Grage-Griebenow
  • M Siedlar
  • Malgorzata Stec
  • B Mytar
  • Bozenna Mytar
  • J Pryjma
  • W Jedrychowski
  • Kazimierz Weglarczyk
  • J Skrzeczynska-Moncznik
  • D Kowalczyk
  • J Baran
  • J Skrzeczynska
  • Antoni Szczepanik
  • Antoni Czupryna
  • Marzena Lenart
  • Jarosław Baran
  • I Ruggiero
  • Rafał Szatanek
  • M Klimaszewska-Rembiasz
  • U Maugeri
  • Jaroslaw Baran
  • E Flak
  • R Jacek
  • E Mroz
  • Monika Baj-Krzyworzeka
  • A Sowa
  • Jolanta Gozdzik
  • Małgorzata Stec
  • M Bzowska
  • S Loseke
  • M Wołoszyn
  • M Gawlicka
  • B Piekarska
  • R Szatanek
  • K Kobylarz
  • Z Hartwich
  • A D B Webster
  • M Woloszyn
  • V Colizzi
  • H D Flad

Detail Information

Publications17

  1. pmc Properties of monocytes generated from haematopoietic CD34(+) stem cells from bone marrow of colon cancer patients
    Malgorzata Stec
    Department of Clinical Immunology and Transplantation, Polish American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka Str 265, 30 663, Cracow, Poland
    Cancer Immunol Immunother 62:705-13. 2013
    ..To our knowledge, it is the first demonstration of such approach that may open a way to obtain autologous monocytes for alternative forms of adaptive and adoptive cellular immunotherapy of cancer...
  2. ncbi request reprint Chemokine receptors and chemokine production by CD34+ stem cell-derived monocytes in response to cancer cells
    Malgorzata Stec
    Department of Clinical Immunology, Polish American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka Str 265, 30 663 Cracow, Poland
    Anticancer Res 32:4749-53. 2012
    ..This study explored the expression of some CR and chemokine production by cord blood stem cell-derived CD34(+) monocytes and their novel CD14(++)CD16(+) and CD14(+)CD16(-) subsets in response to tumour cells...
  3. pmc Biological activity of dendritic cells generated from cord blood CD34+ hematopoietic progenitors in IL-7- and IL-13-conditioned cultures
    Bozenna Mytar
    Department of Clinical Immunology, Polish American Institute of Pediatrics, Jagiellonian University Medical College, Cracow, Poland
    Arch Immunol Ther Exp (Warsz) 57:67-74. 2009
    ..The present study was designed to obtain mDCs from CD34+ hematopoietic progenitors by culturing them in different media...
  4. ncbi request reprint Phenotypic changes of monocytes induced by HIV-1 gp120 molecule and its fragments
    M Zembala
    Department of Clinical Immunology, Jagiellonian University Medical School, Cracow, Poland
    Immunobiology 197:110-21. 1997
    ..These results provide further evidence for variable response of M phi to gp120 which may explain the variability of phenotypic changes and heterogeneity of M phi subsets seen in HIV-1 disease...
  5. ncbi request reprint Demonstration of iNOS-mRNA and iNOS in human monocytes stimulated with cancer cells in vitro
    M Siedlar
    Department of Clinical Immunology, Polish American Institute of Pediatrics, Krakow, Poland
    J Leukoc Biol 65:597-604. 1999
    ..However, because only some tumor cells are able to induce NO production in a small proportion of Mphi, its role in the anti-tumor response of the host is probably limited...
  6. pmc Three-color flow cytometry detection of intracellular cytokines in peripheral blood mononuclear cells: comparative analysis of phorbol myristate acetate-ionomycin and phytohemagglutinin stimulation
    J Baran
    Department of Clinical Immunology, Polish-American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka Str. 265, 30-663 Cracow, Poland
    Clin Diagn Lab Immunol 8:303-13. 2001
    ..We conclude that the use of PHA for cell activation may limit in vitro artifacts and allow more precise analysis of intracellular cytokine production in various disease states...
  7. pmc Induction of reactive oxygen intermediates in human monocytes by tumour cells and their role in spontaneous monocyte cytotoxicity
    B Mytar
    Department of Clinical Immunology, Polish American Institute of Paediatrics, Jagiellonian University Medical College, Wielicka, Cracow, Poland
    Br J Cancer 79:737-43. 1999
    ....
  8. ncbi request reprint Involvement of protein kinases in signalling for nitric oxide (NO) and tumour necrosis factor alpha (TNF) production by monocytes stimulated with colorectal DeTa cancer cells: the lack of evidence for the role of TNF in the regulation of NO production
    M Siedlar
    Department of Clinical Immunology, Polish American Institute of Paediatrics, Jagiellonian University Medical Faculty, Cracow, Poland
    Immunol Lett 65:189-95. 1999
    ..Therefore, signal transduction pathways operating in MO during NO induction seem to be different from these engaged in TNF production, and both regulatory pathways probably operate in MO independently...
  9. doi request reprint Peripheral blood CD14high CD16+ monocytes are main producers of IL-10
    J Skrzeczynska-Moncznik
    Department of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland
    Scand J Immunol 67:152-9. 2008
    ..In conclusion, our data show that human peripheral blood CD16(+) MO are heterogeneous in function and consist of two subpopulations: CD14(dim) CD16(+) pro-inflammatory and CD14(high) CD16(+) with anti-inflammatory potential...
  10. ncbi request reprint CD14+CD16+ monocytes in the course of sepsis in neonates and small children: monitoring and functional studies
    J Skrzeczynska
    Department of Immunology, Institute of Molecular Biology, Jagiellonian University, Medical College, Cracow, Poland
    Scand J Immunol 55:629-38. 2002
    ..The reduced interleukin (IL)-1 but rather increased IL-10 production was associated with sepsis. The differences between CD14+CD16+ monocytes of healthy donors and patients with sepsis are discussed...
  11. ncbi request reprint Induction of intracellular cytokine production in human monocytes/macrophages stimulated with ligands of pattern recognition receptors
    B Mytar
    Department of Clinical Immunology, Polish American Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265, 30 663 Cracow, Poland
    Inflamm Res 53:100-6. 2004
    ....
  12. ncbi request reprint Preactivation and phenotype of monocytes have no influence on their elimination from culture by activated T lymphocytes
    J Pryjma
    Department of Clinical Immunology and Microbiology, Polish American Institute of Pediatrics, Jagiellonian University Medical College, Cracow, Poland
    Arch Immunol Ther Exp (Warsz) 43:31-5. 1995
    ..In conclusion, our data indicate that elimination of monocytes by activated T lymphocytes does not depend on the state of activation of monocytes...
  13. ncbi request reprint Interaction of HIV-1 gp120 molecule fragments with human monocytes: different requirements for tumor necrosis factor-alpha and IL-6 production
    M Zembala
    Department of Clinical Immunology, Polish American Institute of Pediatrics, Jagiellonian University Medical College, Cracow
    Clin Immunol Immunopathol 75:131-9. 1995
    ..The enhanced production of TNF in HIV infection and AIDS may involve distinct cellular sources and different mechanisms...
  14. ncbi request reprint Cross-talk between human monocytes and cancer cells during reactive oxygen intermediates generation: the essential role of hyaluronan
    B Mytar
    Department of Clinical Immunology, Polish-American Institute of Pediatrics, Jagiellonian University Medical College, Cracow, Poland
    Int J Cancer 94:727-32. 2001
    ..Taken together, these observations suggest that the presence of HA in the tumor stroma may modulate effector functions of infiltrating macrophages and their interactions with cancer cells in situ...
  15. ncbi request reprint Maternal allergy as a potential source of variability of exhaled nitric oxide in children non-sensitized to common domestic allergens
    W Jedrychowski
    Jagiellonian University Medical College, Cracow, Poland
    J Physiol Pharmacol 63:257-62. 2012
    ..The data should be considered in the interpretation of FeNO levels in clinical practice and setting up FeNO screening criteria for identification of eosinophilic airway inflammation...
  16. ncbi request reprint Pentoxyfylline in and prevention and treatment of chronic lung disease
    R Lauterbach
    Department of Neonatology, Medical College Jagiellonian University, Cracow, Poland
    Acta Paediatr Suppl 93:20-2. 2004
    ..Interim analysis of a prophylactic trial suggests pentoxyfylline may reduce treatment requirements after the neonatal period and that, in established BPD, pentoxyfylline and dexamethasone may be of similar efficacy...
  17. pmc Intracellular cytokine production by Th1/Th2 lymphocytes and monocytes of children with symptomatic transient hypogammaglobulinaemia of infancy (THI) and selective IgA deficiency (SIgAD)
    D Kowalczyk
    Department of Clinical Immunology, Polish American Institute of Paediatrics, Jagiellonian University Medical College, Cracow, Poland
    Clin Exp Immunol 127:507-12. 2002
    ..Up-regulation of IL-12 may be the essential factor in the patomechanism(s) of these diseases as already described in common variable immunodeficiency (CVID)...