Michał Nowicki

Summary

Affiliation: University of Medical Sciences
Country: Poland

Publications

  1. pmc Prognostic value of stage IV neuroblastoma metastatic immunophenotype in the bone marrow: preliminary report
    M Nowicki
    Department of Histology and Embryology, Poznan University of Medical Sciences, Swiecickiego 6, 60 781 Poznan, Poland
    J Clin Pathol 59:150-2. 2006
  2. ncbi request reprint Prognostic significance of Ki67-negative blast cell clone in the high risk group of children treated for acute myeloid leukaemia
    Michał Nowicki
    Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
    Folia Histochem Cytobiol 44:49-52. 2006
  3. ncbi request reprint Vascular endothelial growth factor C--a potent risk factor in childhood acute lymphoblastic leukaemia: an immunocytochemical approach
    M Nowicki
    Department of Histology and Embryology, Poznan University of Medical Sciences, Dresden, Germany
    Histopathology 49:170-7. 2006
  4. ncbi request reprint [Wilms tumor as a novel model of angiogenesis in childood nephropathies]
    Michał Nowicki
    Katedra Histologii i Embriologii, Akademii Medycznej w Poznaniu
    Przegl Lek 63:87-9. 2006
  5. pmc The predicting role of substance P in the neoplastic transformation of the hypoplastic bone marrow
    M Nowicki
    Department of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poznan, Poland
    J Clin Pathol 59:935-41. 2006
  6. pmc The significance of substance P in physiological and malignant haematopoiesis
    Michal Nowicki
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poland
    J Clin Pathol 60:749-55. 2007
  7. ncbi request reprint The significance of VEGF-C/VEGFR-2 interaction in the neovascularization and prognosis of nephroblastoma (Wilms' tumour)
    M Nowicki
    Department of Paediatric Oncology, Haematology and Transplantology, Poznan University of Medical Sciences, Poznan, Poland
    Histopathology 50:358-64. 2007
  8. doi request reprint Vascular endothelial growth factor (VEGF)-C - a potent risk factor in children diagnosed with stadium 4 neuroblastoma
    Michal Nowicki
    Departments of Paediatric Oncology, University of Medical Sciences, Poland
    Folia Histochem Cytobiol 46:493-9. 2008
  9. pmc Short-term cultivation of porcine cumulus cells influences the cyclin-dependent kinase 4 (Cdk4) and connexin 43 (Cx43) protein expression--a real-time cell proliferation approach
    Bartosz Kempisty
    Department of Histology and Embryology, Poznan University of Medical Sciences, 60 781 Poznan, Poland
    J Reprod Dev 59:339-45. 2013
  10. pmc Expression of INHβA and INHβB proteins in porcine oocytes cultured in vitro is dependent on the follicle size
    Bartosz Kempisty
    Department of Histology and Embryology, Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland
    Zygote 23:205-11. 2015

Collaborators

Detail Information

Publications40

  1. pmc Prognostic value of stage IV neuroblastoma metastatic immunophenotype in the bone marrow: preliminary report
    M Nowicki
    Department of Histology and Embryology, Poznan University of Medical Sciences, Swiecickiego 6, 60 781 Poznan, Poland
    J Clin Pathol 59:150-2. 2006
    ..To correlate the immunophenotype of metastatic cells in the bone marrow of patients with neuroblastoma with early treatment failure...
  2. ncbi request reprint Prognostic significance of Ki67-negative blast cell clone in the high risk group of children treated for acute myeloid leukaemia
    Michał Nowicki
    Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
    Folia Histochem Cytobiol 44:49-52. 2006
    ..The results indicate a possible correlation between the Ki67-immunonegative blast pattern on day 15 of treatment induction and early decease of AML children assigned to HR group...
  3. ncbi request reprint Vascular endothelial growth factor C--a potent risk factor in childhood acute lymphoblastic leukaemia: an immunocytochemical approach
    M Nowicki
    Department of Histology and Embryology, Poznan University of Medical Sciences, Dresden, Germany
    Histopathology 49:170-7. 2006
    ....
  4. ncbi request reprint [Wilms tumor as a novel model of angiogenesis in childood nephropathies]
    Michał Nowicki
    Katedra Histologii i Embriologii, Akademii Medycznej w Poznaniu
    Przegl Lek 63:87-9. 2006
    ..It may also explain the process of glomeruli-dependent physiological development of kidney and, what is also probable, the phenomenon of neoangiogenesis described in individual childhood nephropathies...
  5. pmc The predicting role of substance P in the neoplastic transformation of the hypoplastic bone marrow
    M Nowicki
    Department of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poznan, Poland
    J Clin Pathol 59:935-41. 2006
    ..To estimate the expression of substance P in the haematopoietic cells of hypoplastic bone marrow and define its relationship with the course of bone marrow hypoplasia...
  6. pmc The significance of substance P in physiological and malignant haematopoiesis
    Michal Nowicki
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poland
    J Clin Pathol 60:749-55. 2007
    ..In the future, SP antagonists may be used as anti-neoplastic drugs, for example by direct or indirect blocking of tumour cell proliferation through inhibition of growth factor production and interleukin-1b synthesis...
  7. ncbi request reprint The significance of VEGF-C/VEGFR-2 interaction in the neovascularization and prognosis of nephroblastoma (Wilms' tumour)
    M Nowicki
    Department of Paediatric Oncology, Haematology and Transplantology, Poznan University of Medical Sciences, Poznan, Poland
    Histopathology 50:358-64. 2007
    ..To investigate the immunohistochemical expression of vascular endothelial growth factor (VEGF)-C and VEGFR-2 in nephroblastoma tissue and correlate their presence with the survival rate of children diagnosed with stage III Wilms' tumour...
  8. doi request reprint Vascular endothelial growth factor (VEGF)-C - a potent risk factor in children diagnosed with stadium 4 neuroblastoma
    Michal Nowicki
    Departments of Paediatric Oncology, University of Medical Sciences, Poland
    Folia Histochem Cytobiol 46:493-9. 2008
    ..The proximity of VEGF-C and CD34/VEGFR-2 of NB could be the equivalent of a potentially interesting VEGF-C fashion involving a tumour cell invasion into the blood vessels in an early phase of metastases promoting...
  9. pmc Short-term cultivation of porcine cumulus cells influences the cyclin-dependent kinase 4 (Cdk4) and connexin 43 (Cx43) protein expression--a real-time cell proliferation approach
    Bartosz Kempisty
    Department of Histology and Embryology, Poznan University of Medical Sciences, 60 781 Poznan, Poland
    J Reprod Dev 59:339-45. 2013
    ..Translocation of these proteins into the cytoplasm of CCs after 44 h of IVC may be related to the expansion process. ..
  10. pmc Expression of INHβA and INHβB proteins in porcine oocytes cultured in vitro is dependent on the follicle size
    Bartosz Kempisty
    Department of Histology and Embryology, Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland
    Zygote 23:205-11. 2015
    ..Moreover, the current study clearly demonstrated that inhibin expression is substantially associated with porcine follicle growth and development. ..
  11. ncbi request reprint Comparison of the cell immunophenotype of metastatic and primary foci in stage IV-S neuroblastoma
    Michał Nowicki
    Department of Paediatric Haematology and Oncology, Institute of Paediatrics, University of Medical Sciences, Poznan, Poland
    Folia Histochem Cytobiol 40:297-303. 2002
    ....
  12. ncbi request reprint Detection of substance P and its mRNA in human blast cells in childhood lymphoblastic leukaemia using immunocytochemistry and in situ hybridisation
    Michał Nowicki
    Department of Paediatric Haematology and Oncology, Institute of Paediatrics, Karol Marcinkowski University of Medical Sciences, Poznan, Poland
    Folia Histochem Cytobiol 41:33-6. 2003
    ..SP may be involved in auto- and paracrine mechanisms capable of inducing hyperplasia of the neoplastic cells...
  13. doi request reprint Expression and cellular distribution of estrogen and progesterone receptors and the real-time proliferation of porcine cumulus cells
    Bartosz Kempisty
    Department of Histology and Embryology, Department of Anatomy, PoznanUniversity of Medical Sciences, 6 Swiecickiego St, 60 781 Poznan, Poland
    Zygote 23:836-45. 2015
    ....
  14. doi request reprint Nuclear localization of P-glycoprotein is responsible for protection of the nucleus from doxorubicin in the resistant LoVo cell line
    Witold Szaflarski
    Department of Histology and Embryology, Poznan University of Medical Sciences, H Święcickiego 6, 60 781 Poznan, Poland
    Biomed Pharmacother 67:497-502. 2013
    ..It suggests that the glycoside chain plays a role in the intracellular trafficking of P-gp and may decide about the destination place in the cell. ..
  15. doi request reprint Real-time proliferation of porcine cumulus cells is related to the protein levels and cellular distribution of Cdk4 and Cx43
    Bartosz Kempisty
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
    Theriogenology 80:411-20. 2013
    ..The protein distribution is presumably related to different protein functions during bidirectional communication via gap junction communication...
  16. doi request reprint Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
    Radosław Januchowski
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poland Electronic address
    Int J Biochem Cell Biol 78:248-59. 2016
    ..Our results indicate that ALDH1A1-positive cancer cells can be responsible for drug resistance development in ovarian cancer. Developing more specific ALDH1A1 inhibitors can increase chemotherapy effectiveness in ovarian cancer. ..
  17. doi request reprint Cytokeratin 8 in venous grafts: a factor of unfavorable long-term prognosis in coronary artery bypass grafting patients
    Bartłomiej Perek
    Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, Poznan, Poland
    Cardiol J 20:583-91. 2013
    ....
  18. doi request reprint Effect of brefeldin A and castanospermine on resistant cell lines as supplements in anticancer therapy
    Karolina Wojtowicz
    Department of Histology and Embryology, Poznan University of Medical Sciences, 60 781 Poznan, Poland
    Oncol Rep 35:2896-906. 2016
    ..BFA had no effect on the MFI of W1TR, but CAS led to an increase in the level of intracellular H33342 in W1TR and A2780T1 cells. These results suggest that these compounds are likely to be useful as supplements in anticancer therapy...
  19. doi request reprint Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
    Radosław Januchowski
    Department of Histology and Embryology, Poznan University of Medical Sciences, Święcickiego 6St, Post code 61 781, Poznan, Poland Electronic address
    Biomed Pharmacother 68:447-53. 2014
    ..Identifying correlations between specific drug transporters and cytostatic drug resistance will require further investigation. ..
  20. ncbi request reprint Substance P--a potent risk factor in childhood lymphoblastic leukaemia
    M Nowicki
    Department of Paediatric Haematology and Oncology, Institute of Paediatrics, Poznan, Poland
    Leukemia 17:1096-9. 2003
    ..The results showed a connection between the presence of SP-positive blasts and leukaemia relapse. This may indicate that SP expression, involved in the proliferation of the tumour cells, may represent a novel risk factor in ALL...
  21. pmc Increased Expression of Several Collagen Genes is Associated with Drug Resistance in Ovarian Cancer Cell Lines
    Radosław Januchowski
    1 Department of Histology and Embryology, Poznan University of Medical Sciences, Poland
    J Cancer 7:1295-310. 2016
    ..The expression pattern of COL genes provide a preliminary view into the role of these proteins in cytostatic drug resistance of cancer cells. The exact role of these COL genes in drug resistance requires further investigation. ..
  22. pmc Microfluidic method of pig oocyte quality assessment in relation to different follicular size based on lab-on-chip technology
    Bartosz Kempisty
    Department of Histology and Embryology, Poznan University of Medical Sciences, 6 Swiecickiego Street, 60 781 Poznan, Poland Department of Anatomy, Poznan University of Medical Science, 6 Swiecickiego Street, 60 781 Poznan, Poland
    Biomed Res Int 2014:467063. 2014
    ..Further investigations with functional-biological assays and comparing LOC analyses with fertilization and pregnancy success and the outcome of healthy offspring must be performed. ..
  23. ncbi request reprint Expression of intermediate filaments of podocytes within nephrotic syndrome glomerulopathies in children
    Danuta Ostalska-Nowicka
    Department of Pediatric Cardiology, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Histochem Cell Biol 121:109-13. 2004
    ..The application of antibodies against intermediate filaments may help to differentiate between mature and immature forms of MesGN...
  24. pmc Analysis of MDR genes expression and cross-resistance in eight drug resistant ovarian cancer cell lines
    Radosław Januchowski
    Department of Histology and Embryology, Poznan University of Medical Sciences, Swiecickiego 6 St, 61 781, Poznan, Poland
    J Ovarian Res 9:65. 2016
    ..Flow cytometry was used to determine the activity of drug transporters...
  25. doi request reprint Expression and cellular distribution of zona pellucida glycoproteins in canine oocytes before and after in vitro maturation
    Bartosz Kempisty
    Department of Histology and Embryology, Department of Anatomy, Poznan University of Medical Sciences, 6 Swiecickiego St, 60 781 Poznan, Poland
    Zygote 23:863-73. 2015
    ..However, a decreased expression of ZP3 and ZP4 proteins after IVM suggests maturation-dependent down-regulation of these protein translations, which may result in disturbed fertilization. ..
  26. doi request reprint Expression profiles of vault components MVP, TEP1 and vPARP and their correlation to other multidrug resistance proteins in ovarian cancer
    Witold Szaflarski
    Department of Histology and Embryology, Poznan University of Medical Sciences, 60 781 Poznan, Poland
    Int J Oncol 43:513-20. 2013
    ..Surprisingly, the protein levels of MVP, TEP1 and vPARP are actually increased in the higher‑grade tumors suggesting existence of post-transcriptional regulation of vault component production...
  27. ncbi request reprint Molecular basis of mechanisms of steroid resistance in children with nephrotic syndrome
    Monika Swierczewska
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
    Acta Biochim Pol 60:339-44. 2013
    ..Moreover, we presented genetic defects, which can lead to various effects of treatment and, in a longer perspective, enable clinicians to individualize therapies...
  28. ncbi request reprint In vitro substance P-dependent induction of bone marrow cells in common (CD10) acute lymphoblastic leukaemia
    M Nowicki
    Department of Histology and Embryology, University of Medical Sciences in Poznan, Swiecickiego 6, 60 781 Poznan, Poland
    Leuk Res 32:97-102. 2008
    ..These findings suggest the novel possible role of SP in blasts proliferation in childhood ALL of common (CD10) origin...
  29. doi request reprint SOCS3 is epigenetically up-regulated in steroid resistant nephrotic children
    Katarzyna Zaorska
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
    Acta Biochim Pol 63:131-138. 2016
    ..Here, we investigate genetic and epigenetic mechanisms of regulation of SOCS3 and SOCS5 transcription in nephrotic children...
  30. pmc Influence of Estradiol-17beta on Progesterone and Estrogen Receptor mRNA Expression in Porcine Follicular Granulosa Cells during Short-Term, In Vitro Real-Time Cell Proliferation
    Sylwia Ciesiółka
    Department of Histology and Embryology, Poznan University of Medical Sciences, 6 Swiecickiego St, 60 781 Poznan, Poland
    Biomed Res Int 2016:8431018. 2016
    ..Since esrrb3 expression is stimulated by E2 in both an acute and prolonged manner, estradiol may be recognized as a potential estrogen receptor agonist in GCs...
  31. doi request reprint Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
    Karolina Wojtowicz
    Department of Histology and Embryology, Poznan University of Medical Sciences, 60 781 Poznan, Poland Electronic address
    Biomed Pharmacother 74:49-56. 2015
    ..Tunicamycin blocks the first step of P-gp (glycoprotein P) and BCRP (breast cancer resistance protein) N-glycosylation, which is a very important modification for the activity and cellular localisation of these proteins...
  32. ncbi request reprint Polymorphic variants of MIF gene and prognosis in steroid therapy in children with idiopathic nephrotic syndrome
    Monika Swierczewska
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poland
    Acta Biochim Pol 61:67-75. 2014
    ..The aim of this study was looking for a correlation between MIF polymorphisms and genetic susceptibility to steroid resistance in children with INS (Idiopathic NS)...
  33. pmc Extracellular matrix proteins expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
    Radosław Januchowski
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poland Święcickiego 6 Street, 61 781 Poznan, Poland
    Biomed Res Int 2014:365867. 2014
    ..Identifying correlations between investigated genes and drug resistance will require further analysis...
  34. ncbi request reprint Correlation between early treatment failure and Ki67 antigen expression in blast cells of children with acute lymphoblastic leukaemia before commencing treatment. A retrospective study
    Michał Nowicki
    Department of Paediatric Haematology and Oncology, Institute of Paediatrics, Karol Marcinkowski University of Medical Sciences, Poznan, Poland
    Oncology 62:55-9. 2002
    ....
  35. doi request reprint Acute and subacute (28-day) toxicity studies of ionic liquid, didecyldimethyl ammonium acesulfamate, in rats
    Jadwiga Jodynis-Liebert
    Department of Toxicology, University of Medical Sciences, Poznan, Poland
    Drug Chem Toxicol 32:395-404. 2009
    ..No treatment-related microscopic changes were observed. Under the conditions of this study, the lowest-observed-adverse-effect level of [DDA][Ace] was considered to be 10 mg/kg/day...
  36. pmc Expression and cellular distribution of INHA and INHB before and after in vitro cultivation of porcine oocytes isolated from follicles of different size
    Bartosz Kempisty
    Department of Histology and Embryology, Poznan University of Medical Sciences, 6 Swiecickiego St, 60 781 Poznan, Poland
    J Biomed Biotechnol 2012:742829. 2012
    ..Similarly and both before and after IVM, INHB protein was highly expressed in small follicle oocytes and within the cytoplasm. In summary, INHs can be recognized as a marker of porcine oocyte quality...
  37. ncbi request reprint Inhibitors of N-glycosylation as a potential tool for analysis of the mechanism of action and cellular localisation of glycoprotein P
    Karolina Wojtowicz
    Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
    Acta Biochim Pol 59:445-50. 2012
    ..Here, we review the basic knowledge on N-glycosylation inhibitors, their effect on glycoprotein P and their therapeutic potential...
  38. pmc Histological evaluation of age-related variations in saphenous vein grafts used for coronary artery bypass grafting
    Bartłomiej Perek
    Department of Cardiac Surgery, Poznan University of Medical Sciences, Poland
    Arch Med Sci 8:1041-7. 2012
    ..The aim of the study was to assess histological representative features of saphenous vein reconstruction in aging as well as to establish optimal patients' age limits applicable for optimal selection of grafts...
  39. ncbi request reprint Vascular endothelial growth factor (VEGF-C1)-dependent inflammatory response of podocytes in nephrotic syndrome glomerulopathies in children: an immunohistochemical approach
    D Ostalska-Nowicka
    Department of Paediatric Cardiology and Nephrology, Poznan University of Medical Sciences, Poland
    Histopathology 46:176-83. 2005
    ..To analyse expression and distribution of vascular endothelial growth factor (VEGF-C1), podocalyxin and synaptopodin within renal tissue in nephrotic syndrome glomerulopathies in children...
  40. pmc Ezrin--a useful factor in the prognosis of nephrotic syndrome in children: an immunohistochemical approach
    D Ostalska-Nowicka
    Department of Pediatric Cardiology and Nephrology, Poznan University of Medical Sciences, Poznan, Poland
    J Clin Pathol 59:916-20. 2006
    ..Although the clinical processes of DMP-S and DMP-R are initially identical, resistance to steroids may be foreseen by the immunohistochemical expression of cytoskeleton-associated proteins in podocytes...