L Struzynska

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. doi Aroclor 1254 selectively inhibits expression of glial GLT-1 glutamate transporter in the forebrain of chronically exposed adult rat
    Lidia Struzynska
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    Toxicology 300:12-8. 2012
  2. ncbi The protective role of astroglia in the early period of experimental lead toxicity in the rat
    L Struzynska
    Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Acta Neurobiol Exp (Wars) 60:167-73. 2000
  3. doi A glutamatergic component of lead toxicity in adult brain: the role of astrocytic glutamate transporters
    Lidia Struzynska
    Department of Neurochemistry, Laboratory of Pathoneurochemistry, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Neurochem Int 55:151-6. 2009
  4. ncbi Changes in expression of neuronal and glial glutamate transporters in lead-exposed adult rat brain
    Lidia Struzynska
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Neurochem Int 47:326-33. 2005
  5. ncbi The role of astroglia in Pb-exposed adult rat brain with respect to glutamate toxicity
    Lidia Struzynska
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    Toxicology 212:185-94. 2005
  6. ncbi Relationships between glutamine, glutamate, and GABA in nerve endings under Pb-toxicity conditions
    Lidia Struzynska
    Laboratory of Pathobiochemistry of the Central Nervous System, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    J Inorg Biochem 98:951-8. 2004
  7. ncbi Lead stimulates the glutathione system in selective regions of rat brain
    Lidia Struzynska
    Laboratory of Pathobiochemistry of the Central Nervous System, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    Folia Neuropathol 40:203-9. 2002
  8. ncbi Astroglial reaction during the early phase of acute lead toxicity in the adult rat brain
    L Struzynska
    Department of Neurochemistry, Laboratory of Pathobiochemistry of the Central Nervous System, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego St, 02 106, Warsaw, Poland
    Toxicology 165:121-31. 2001
  9. ncbi Myelin glycoproteins targeted by lead in the rodent model of prolonged exposure
    B Dabrowska-Bouta
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Warsaw, Poland
    Food Chem Toxicol 46:961-6. 2008
  10. ncbi The influence of glutamatergic receptor antagonists on biochemical and ultrastructural changes in myelin membranes of rats subjected to experimental autoimmune encephalomyelitis
    Beata Dabrowska-Bouta
    Grzegorz Sulkowski, Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Centre Polish Academy of Sciences, 5 Pawinskiego St, 02 106 Warsaw, Poland, phone 48 22 608 65 30, fax 48 22 608 54 23, E mail
    Folia Neuropathol 53:317-26. 2015

Collaborators

Detail Information

Publications11

  1. doi Aroclor 1254 selectively inhibits expression of glial GLT-1 glutamate transporter in the forebrain of chronically exposed adult rat
    Lidia Struzynska
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    Toxicology 300:12-8. 2012
    ..Conversely, we observed enhanced glutamate uptake into nerve-endings fractions paralleled by increased EAAC1 protein expression. This may reflect the induction of protective mechanisms...
  2. ncbi The protective role of astroglia in the early period of experimental lead toxicity in the rat
    L Struzynska
    Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Acta Neurobiol Exp (Wars) 60:167-73. 2000
    ..The activity of the marker enzyme--glutamine synthetase (GS) was also significantly increased in the GPV fraction. The activation of glial functions suggest a regulatory role for these cells in the early period of acute lead toxicity...
  3. doi A glutamatergic component of lead toxicity in adult brain: the role of astrocytic glutamate transporters
    Lidia Struzynska
    Department of Neurochemistry, Laboratory of Pathoneurochemistry, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Neurochem Int 55:151-6. 2009
    ..Our observations are viewed against a background of other results...
  4. ncbi Changes in expression of neuronal and glial glutamate transporters in lead-exposed adult rat brain
    Lidia Struzynska
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Neurochem Int 47:326-33. 2005
    ..This observation suggests that under conditions of Pb toxicity in adult rat brain, the hippocampus is most vulnerable to the excitotoxic cell damage arising from impaired clearance of the released glutamate...
  5. ncbi The role of astroglia in Pb-exposed adult rat brain with respect to glutamate toxicity
    Lidia Struzynska
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    Toxicology 212:185-94. 2005
    ....
  6. ncbi Relationships between glutamine, glutamate, and GABA in nerve endings under Pb-toxicity conditions
    Lidia Struzynska
    Laboratory of Pathobiochemistry of the Central Nervous System, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    J Inorg Biochem 98:951-8. 2004
    ....
  7. ncbi Lead stimulates the glutathione system in selective regions of rat brain
    Lidia Struzynska
    Laboratory of Pathobiochemistry of the Central Nervous System, Department of Neurochemistry, Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    Folia Neuropathol 40:203-9. 2002
    ..Regional differences in the pattern of these changes may coincide with different susceptibility to Pb. Present results suggest also that mitochondrial mechanisms might account for lead toxicity...
  8. ncbi Astroglial reaction during the early phase of acute lead toxicity in the adult rat brain
    L Struzynska
    Department of Neurochemistry, Laboratory of Pathobiochemistry of the Central Nervous System, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego St, 02 106, Warsaw, Poland
    Toxicology 165:121-31. 2001
    ..It may indicate lead-induced neuronal injury. At the same time, a regional enhancement of detoxicative mechanisms (GSH) was noticed, suggesting activation of astrocyte-mediated neuroprotection against toxic Pb action...
  9. ncbi Myelin glycoproteins targeted by lead in the rodent model of prolonged exposure
    B Dabrowska-Bouta
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Warsaw, Poland
    Food Chem Toxicol 46:961-6. 2008
    ..These results suggest that Pb influences the integrity of the myelin sheath in brain of adult rats and decreased level of both glycoproteins may significantly contribute to that effect...
  10. ncbi The influence of glutamatergic receptor antagonists on biochemical and ultrastructural changes in myelin membranes of rats subjected to experimental autoimmune encephalomyelitis
    Beata Dabrowska-Bouta
    Grzegorz Sulkowski, Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Centre Polish Academy of Sciences, 5 Pawinskiego St, 02 106 Warsaw, Poland, phone 48 22 608 65 30, fax 48 22 608 54 23, E mail
    Folia Neuropathol 53:317-26. 2015
    ..The results reveal that glutamate receptor antagonists have a positive effect on the expression of mRNA MBP and glycoproteins MAG and MOG but not on myelin ultrastructure. ..
  11. ncbi Expression of purinergic P2X7 receptor in rat brain during the symptomatic phase of experimental autoimmune encephalomyelitis and after recovery of neurological deficits
    Tomasz Grygorowicz
    Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Acta Neurobiol Exp (Wars) 71:65-73. 2011
    ..Results suggest the involvement of P2X(7)R-mediated signaling in the pathomechanisms of EAE with the possible relevance of astrocytic pool of cells...