Edyta Paradowska

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. doi request reprint Cytomegalovirus alpha-chemokine genotypes are associated with clinical manifestations in children with congenital or postnatal infections
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland Electronic address
    Virology 462:207-17. 2014
  2. doi request reprint Distribution of cytomegalovirus gN variants and associated clinical sequelae in infants
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    J Clin Virol 58:271-5. 2013
  3. doi request reprint Distribution of UL144, US28 and UL55 genotypes in Polish newborns with congenital cytomegalovirus infections
    E Paradowska
    Institute of Medical Biology, Polish Academy of Sciences, Laboratory of Molecular Virology and Biological Chemistry, Lodowa 106, 93 232, Lodz, Poland
    Eur J Clin Microbiol Infect Dis 31:1335-45. 2012
  4. ncbi request reprint Detection of cytomegalovirus in human placental cells by polymerase chain reaction
    Edyta Paradowska
    Center for Medical Biology, Polish Academy of Sciences, Laboratory of Molecular Virology and Biological Chemistry, Lodz, Poland
    APMIS 114:764-71. 2006
  5. pmc Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children
    Mirosława Studzińska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    PLoS ONE 12:e0169420. 2017
  6. pmc TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    PLoS ONE 11:e0154100. 2016
  7. doi request reprint Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    J Med Virol 86:1421-7. 2014
  8. doi request reprint Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection
    Agnieszka Jabłońska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St, 93 232 Lodz, Poland
    Int J Infect Dis 25:11-5. 2014
  9. doi request reprint Human cytomegalovirus UL55, UL144, and US28 genotype distribution in infants infected congenitally or postnatally
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    J Med Virol 87:1737-48. 2015
  10. doi request reprint Mannan-binding lectin-2 (MBL2) gene polymorphisms in prenatal and perinatal cytomegalovirus infections
    Agnieszka Szala
    Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93 232 Lodz, Poland
    Mol Immunol 48:2203-6. 2011

Collaborators

Detail Information

Publications16

  1. doi request reprint Cytomegalovirus alpha-chemokine genotypes are associated with clinical manifestations in children with congenital or postnatal infections
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland Electronic address
    Virology 462:207-17. 2014
    ..There was a strong correlation between HCMV genotypes determined through the UL146 and UL147 sequences (ĸ=0.794). In conclusion, we found that certain vCXCL genotypes are associated with clinical sequelae following HCMV infection. ..
  2. doi request reprint Distribution of cytomegalovirus gN variants and associated clinical sequelae in infants
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    J Clin Virol 58:271-5. 2013
    ..Human cytomegalovirus (HCMV) is the most widespread cause of congenital infection. The effects of various viral strains and viral loads on the infection outcome have been under debate...
  3. doi request reprint Distribution of UL144, US28 and UL55 genotypes in Polish newborns with congenital cytomegalovirus infections
    E Paradowska
    Institute of Medical Biology, Polish Academy of Sciences, Laboratory of Molecular Virology and Biological Chemistry, Lodowa 106, 93 232, Lodz, Poland
    Eur J Clin Microbiol Infect Dis 31:1335-45. 2012
    ..0002 and p=0.040 respectively). There was no association between specific gB subtypes in all patients groups (p=0.463). There was no correlation between HCMV genotypes and the outcome...
  4. ncbi request reprint Detection of cytomegalovirus in human placental cells by polymerase chain reaction
    Edyta Paradowska
    Center for Medical Biology, Polish Academy of Sciences, Laboratory of Molecular Virology and Biological Chemistry, Lodz, Poland
    APMIS 114:764-71. 2006
    ..Our results demonstrated that detection of HCMV DNA in placental tissues by DNA amplification provides a specific and sensitive method for diagnosis of intrauterine HCMV infection...
  5. pmc Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children
    Mirosława Studzińska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    PLoS ONE 12:e0169420. 2017
    ..A moderate linkage disequilibrium (LD) was observed between the SNPs rs3775291 and rs3775296 (r2 = 0.514). We suggest that the L412F polymorphism in the TLR3 gene could be a genetic risk factor for the development of HCMV disease...
  6. pmc TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    PLoS ONE 11:e0154100. 2016
    ..We found no evidence for linkage disequilibrium with the four examined TLR9 SNPs. The findings suggest that the TLR9 -1486T/C and 2848C/T polymorphisms could be a genetic risk factor for the development of HCMV disease. ..
  7. doi request reprint Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    J Med Virol 86:1421-7. 2014
    ..However, these results suggest that the gH genotype might be associated with hearing loss in children...
  8. doi request reprint Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection
    Agnieszka Jabłońska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St, 93 232 Lodz, Poland
    Int J Infect Dis 25:11-5. 2014
    ..The association among specific single-nucleotide polymorphisms (SNPs) in TLR2 (Arg677Trp, Arg753Gln) and TLR4 (Asp299Gln) and human cytomegalovirus (CMV) infection was studied in infants and adults...
  9. doi request reprint Human cytomegalovirus UL55, UL144, and US28 genotype distribution in infants infected congenitally or postnatally
    Edyta Paradowska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
    J Med Virol 87:1737-48. 2015
    ..The results revealed that UL55, UL144, and US28 polymorphisms are not associated with the outcome of CMV infection in infants, but the presence of UL144 B1 genotype might be virological marker of asymptomatic infection at birth...
  10. doi request reprint Mannan-binding lectin-2 (MBL2) gene polymorphisms in prenatal and perinatal cytomegalovirus infections
    Agnieszka Szala
    Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93 232 Lodz, Poland
    Mol Immunol 48:2203-6. 2011
    ..The distribution of MBL2 haplotypes was similar between the groups studied. These data suggest MBL does not have a major influence on susceptibility to prenatal or perinatal CMV infections...
  11. pmc TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus
    Wioletta Wujcicka
    Scientific Laboratory of Center of Medical Laboratory Diagnostics, Polish Mother s Memorial Hospital Research Institute, Lodz, Poland
    PLoS ONE 10:e0122831. 2015
    ..The study was aimed to assess the correlation of SNPs at TLR4 and TLR9 genes with the occurrence of congenital cytomegaly, based on available samples...
  12. ncbi request reprint Modification of selected anti-HCMV drugs with lipophilic boron cluster modulator
    Agnieszka B Olejniczak
    Institute of Medical Biology, Polish Academy of Sciences, Laboratory of Molecular Virology and Biological Chemistry, 106 Lodowa St, 93 232 Lodz, Poland
    Acta Pol Pharm 70:489-504. 2013
    ..The compounds were active against HCMV or HSV-1 by cytopathic effect or plaque reduction assays. None of the tested compounds had activity against HPIV-3 or VSV...
  13. pmc TLR2 2258 G>A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus
    Wioletta Wujcicka
    Scientific Laboratory of the Center of Medical Laboratory Diagnostics and Screening, Polish Mother s Memorial Hospital Research Institute, 281 289 Rzgowska Street, Lodz, 93 338, Poland
    Virol J 14:12. 2017
    ....
  14. doi request reprint Anti-mycobacterial activity of thymine derivatives bearing boron clusters
    Anna Adamska
    Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology PAS, 106 Lodowa St, 93 232 Lodz, Poland
    Eur J Med Chem 121:71-81. 2016
    ..Both compounds completely inhibited M. smegmatis proliferation at a concentration of 100 μg/mL (0.25 mM and 0.15 mM, respectively). ..
  15. ncbi request reprint Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their nucleoside conjugates
    Zbigniew J Lesnikowski
    Center of Medical Biology, Laboratory of Molecular Virology and Biological Chemistry, Polish Academy of Sciences, 106 Lodowa Street, Lodz 93 232, Poland
    Bioorg Med Chem 13:4168-75. 2005
    ..The low toxicity of conjugate type of 6 together with its high partition coefficient suggest that judicially designed derivatives of metallacarboranes can be considered as potential boron carriers for BNCT...
  16. ncbi request reprint [Drugs against human cytomegalovirus]
    Zbigniew J Lesnikowski
    Department of Virology, Royal Free and University College Medical School, London
    Pol Merkur Lekarski 13:242-9. 2002
    ..In this outline we present anti-CMV drugs currently in clinical use and give examples of new molecules under laboratory and clinical development...