Maria Barcikowska

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. ncbi request reprint Prediction of deterioration of mild cognitive impairment with CT and SPECT
    Tomasz Gabryelewicz
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Warsaw, Poland
    Med Sci Monit 13:31-7. 2007
  2. doi request reprint Analysis of UBQLN1 variants in a Polish Alzheimer's disease patient: control series
    Maciej P Golan
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Dement Geriatr Cogn Disord 25:366-71. 2008
  3. pmc PIN1 gene variants in Alzheimer's disease
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    BMC Med Genet 10:115. 2009
  4. ncbi request reprint New therapeutic approaches in Alzheimer's disease
    Maria Barcikowska
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Warszawa
    Folia Neuropathol 42:251-5. 2004
  5. ncbi request reprint Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease
    Maria Styczynska
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    Neurosci Lett 344:99-102. 2003
  6. ncbi request reprint Sigma receptor type 1 gene variation in a group of Polish patients with Alzheimer's disease and mild cognitive impairment
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Dement Geriatr Cogn Disord 23:432-8. 2007
  7. doi request reprint Mitochondrial haplogroup H and Alzheimer's disease--is there a connection?
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Polish Academy of Sciences Medical Research Center, 5 Pawinskiego Street, 02 106 Warsaw, Poland
    Neurobiol Aging 30:1749-55. 2009
  8. ncbi request reprint Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: genetic and bioinformatic assessment
    Cezary Zekanowski
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    Exp Neurol 200:82-8. 2006
  9. ncbi request reprint Association between genetic and environmental factors and the risk of Alzheimer's disease
    Maria Styczynska
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego St, 02 106 Warsaw, Poland
    Folia Neuropathol 46:249-54. 2008
  10. ncbi request reprint CYP46: a risk factor for Alzheimer's disease or a coincidence?
    Ewa Golanska
    Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Poland
    Neurosci Lett 383:105-8. 2005

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Prediction of deterioration of mild cognitive impairment with CT and SPECT
    Tomasz Gabryelewicz
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Warsaw, Poland
    Med Sci Monit 13:31-7. 2007
    ..The objective of this study was to examine baseline differences between MCI subjects who did or did not deteriorate at follow-up on measures of cognition and neuroimaging...
  2. doi request reprint Analysis of UBQLN1 variants in a Polish Alzheimer's disease patient: control series
    Maciej P Golan
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Dement Geriatr Cogn Disord 25:366-71. 2008
    ..However, the association observed seems to be driven mostly by rare (<5%) haplotypes. Results suggest a need for additional association studies and in silico analysis of the UBQLN1 locus...
  3. pmc PIN1 gene variants in Alzheimer's disease
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    BMC Med Genet 10:115. 2009
    ..There are confounding results concerning PIN1 activity in AD brains. Also PIN1 genetic variation was inconsistently associated with AD risk...
  4. ncbi request reprint New therapeutic approaches in Alzheimer's disease
    Maria Barcikowska
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Warszawa
    Folia Neuropathol 42:251-5. 2004
    ..There is a great need for finding routine biomarkers and sensitive enough clinical tests for diagnosis of AD in which the lasting pathological process does not destroy too many neurones...
  5. ncbi request reprint Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease
    Maria Styczynska
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego Str, 02 106 Warsaw, Poland
    Neurosci Lett 344:99-102. 2003
    ..Our results suggest that the APOE epsilon 4 allele is the only known genetic risk factor for late-onset, sporadic AD...
  6. ncbi request reprint Sigma receptor type 1 gene variation in a group of Polish patients with Alzheimer's disease and mild cognitive impairment
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Dement Geriatr Cogn Disord 23:432-8. 2007
    ..Multivariate logistic regression analysis showed no interaction between the APOE4 and SIGMAR1 polymorphisms. Further studies using data from different populations are required to elucidate the effect of SIGMAR1 polymorphisms on AD...
  7. doi request reprint Mitochondrial haplogroup H and Alzheimer's disease--is there a connection?
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Polish Academy of Sciences Medical Research Center, 5 Pawinskiego Street, 02 106 Warsaw, Poland
    Neurobiol Aging 30:1749-55. 2009
    ..We conclude that further analysis of subtypes of haplogroup H would be necessary to decipher the relation of HV cluster with AD...
  8. ncbi request reprint Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: genetic and bioinformatic assessment
    Cezary Zekanowski
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    Exp Neurol 200:82-8. 2006
    ..We also propose that PSEN1 mutations should be considered in FTD patients with no MAPT mutations...
  9. ncbi request reprint Association between genetic and environmental factors and the risk of Alzheimer's disease
    Maria Styczynska
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, 5 Pawinskiego St, 02 106 Warsaw, Poland
    Folia Neuropathol 46:249-54. 2008
    ..005). Plasma total homocysteine was increased and vitamin B12 decreased in AD patients (p<0.001). The influence of APOE epsilon4 and NOS3 G alleles on the risk of AD was independent of homocysteine, vitamin B12 levels and MTHFR status...
  10. ncbi request reprint CYP46: a risk factor for Alzheimer's disease or a coincidence?
    Ewa Golanska
    Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Poland
    Neurosci Lett 383:105-8. 2005
    ..However, considering the extreme divergence of results obtained by different authors, a clear connection between the CYP46 gene and AD is questionable...
  11. ncbi request reprint Cognitive deficits and polymorphism of apolipoprotein E in Alzheimer's disease
    Elizbieta Luczywek
    Department of Neurosurgery, Medical Research Center, Nencki Institute of Experimental Biology, Warsaw, Poland
    Dement Geriatr Cogn Disord 13:171-7. 2002
    ..On the other hand, working memory appeared to be more impaired in the epsilon4- group of patients. Independent of the genotype, both groups showed similar impairment of learning ability without, however, deficits in remote memory...
  12. ncbi request reprint The E318G substitution in PSEN1 gene is not connected with Alzheimer's disease in a large Polish cohort
    Cezary Zekanowski
    Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, ul Ksiecia Trojdena 4, PL 02 109 Warszawa, Poland
    Neurosci Lett 357:167-70. 2004
    ..It could be concluded that E318G mutation is not related causally to AD in the Polish population, either as a risk factor or a disease causing mutation...
  13. ncbi request reprint Mutations in presenilin 1, presenilin 2 and amyloid precursor protein genes in patients with early-onset Alzheimer's disease in Poland
    Cezary Zekanowski
    Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, 02 109 Warsaw, Poland
    Exp Neurol 184:991-6. 2003
    ..It could be concluded that screening for mutations in the three genes could be included in a diagnostic program directed at patients with a positive family history or age of onset before 55 years...
  14. ncbi request reprint Strong association between Saitohin gene polymorphism and tau haplotype in the Polish population
    Beata Pepłońska
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warsaw, Poland
    Neurosci Lett 348:163-6. 2003
    ..We found that the R allele of the STH gene is associated with the H2 haplotype of tau in all cases. Additionally we observed no correlation between R allele frequency and AD or PD...
  15. ncbi request reprint [Fronto-temporal dementia and parkinsonism linked to chromosome 17 (FTDP-17): clinical criteria]
    Zbigniew K Wszolek
    Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
    Neurol Neurochir Pol 37:173-84. 2003
    ..Undoubtedly further research into the FTDP-17 will contribute to the development of a successful treatment for these devastating degenerative diseases of the c.n.s...
  16. ncbi request reprint Mutation screening of the MAPT and STH genes in Polish patients with clinically diagnosed frontotemporal dementia
    Cezary Zekanowski
    Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology in Warsaw, Poland
    Dement Geriatr Cogn Disord 16:126-31. 2003
    ..At the STH gene only a common polymorphic change was found. It is postulated that MAPT mutations are not connected with most of the FTD cases in the Polish population...
  17. ncbi request reprint Plasma beta amyloid and cytokine profile in women with Alzheimer's disease
    Agnieszka Baranowska-Bik
    Neuroendocrinology Department, Medical Centre of Postgraduate Education, Warsaw, Poland
    Neuro Endocrinol Lett 29:75-9. 2008
    ..However, those differences were not statistically significant. In addition, we did not detect any correlations between plasma beta amyloid and investigated cytokines...
  18. ncbi request reprint Polish Centenarians Programme. Multidisciplinary studies of successful ageing: aims, methods, and preliminary results
    Malgorzata Mossakowska
    International Institute of Molecular and Cell Biology, Warsaw, Poland
    Exp Gerontol 43:238-44. 2008
    ..In this study, 346 subjects aged 100+ were visited, biological material was collected from 285 subjects, and 153 lymphocyte cell lines were immortalized...
  19. ncbi request reprint Association study of cholesterol-related genes in Alzheimer's disease
    M Axel Wollmer
    Division of Psychiatry Research, University of Zurich, August Forel Str 1, 8008 Zurich, Switzerland
    Neurogenetics 8:179-88. 2007
    ..004). We conclude that genetic variants investigated in this study may be associated with a moderate modification of the risk for AD in some samples...
  20. ncbi request reprint [Alzheimer's disease therapy--theory and practice]
    Tomasz Gabryelewicz
    Z Zakładu Badawczo Leczniczego Chorób Zwyrodnieniowych GUN IMDiK PAN w Warszawie
    Wiad Lek 58:528-35. 2005
    ..Relevant double-blind, randomized, placebo-controlled studies were identified through a comprehensive search of Medline, NICE, Embase and CENTRAL databases...
  21. ncbi request reprint [Lactoferrin in the central nervous system]
    Mariusz Sacharczuk
    Zakład Cytogenetyki Molekularnej, Instytut Genetyki i Hodowli Zwierzat, Polska Akademia Nauk, ul Postepu 1, 05 552 Jastrzebiec
    Neurol Neurochir Pol 39:482-9. 2005
    ..LF suppresses distress perception via opioid mediated mechanism and prevents a decrease of the immune system activity caused by psychosocial stress. Furthermore, LF possibly modulates behavior in man and in animals...
  22. ncbi request reprint An open-label study to evaluate the safety, tolerability and efficacy of rivastigmine in patients with mild to moderate probable Alzheimer's disease in the community setting
    Adam Bilikiewicz
    2nd Clinic of Mental Diseases, Medical University of Gdansk, ul Srebrniki 1, 80 282 Gdańsk, Poland
    Med Sci Monit 8:PI9-15. 2002
    ..Long-term safety and efficacy of Exelon (rivastigmine) was evaluated in a multi-center open-label study of 62 patients with probable mild to moderate Alzheimer's disease living in community setting...