A Gzyl

Summary

Affiliation: National Institute of Hygiene
Country: Poland

Publications

  1. ncbi request reprint Temporal nucleotide changes in pertactin and pertussis toxin genes in Bordetella pertussis strains isolated from clinical cases in Poland
    A Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, Chocimska Street 24, 00 791 Warsaw, Poland
    Vaccine 20:299-303. 2001
  2. ncbi request reprint Amplified fragment length polymorphism (AFLP) versus randomly amplified polymorphic DNA (RAPD) as new tools for inter- and intra-species differentiation within Bordetella
    Anna Gzyl
    Department of Sera and Vaccine Evaluation, National Institute of Hygiene, 24 Chocimska Str, 00 791 Warsaw, Poland
    J Med Microbiol 54:333-46. 2005
  3. ncbi request reprint Potency of pertussis component in the DTP vaccine--an overview of three decade study in Poland
    Anna Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, Chocimska Str 24, 00 791 Warsaw, Poland
    Biologicals 32:129-37. 2004
  4. ncbi request reprint [Genetic variability of Bordetella pertussis strains. Part I. Current knowledge]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 57:181-92. 2003
  5. ncbi request reprint [Genetic variability of Bordetella pertussis strains. Part II. Perspectives]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 57:193-200. 2003
  6. ncbi request reprint Sequence variation in pertussis S1 subunit toxin and pertussis genes in Bordetella pertussis strains used for the whole-cell pertussis vaccine produced in Poland since 1960: efficiency of the DTwP vaccine-induced immunity against currently circulating B.
    Anna Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, Chocimska Street 24, 00 791 Warsaw, Poland
    Vaccine 22:2122-8. 2004
  7. ncbi request reprint Pertussis in Poland
    Anna Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, 24 Chocimska Str, 00 791 Warsaw, Poland
    Int J Epidemiol 33:358-65. 2004
  8. ncbi request reprint [Sources of information and knowledge on childhood immunisations among Polish parents]
    Justyna Rogalska
    Zakład Epidemiologii, Narodowego Instytutu Zdrowia Publicznego Państwowego Zakładu Higieny w Warszawie
    Przegl Epidemiol 64:83-90. 2010
  9. ncbi request reprint [Parental attitudes towards childhood immunisations in Poland]
    Justyna Rogalska
    Zakład Epidemiologii, Narodowego Instytutu Zdrowia Publicznego Państwowego Zakładu Higieny w Warszawie
    Przegl Epidemiol 64:91-7. 2010
  10. ncbi request reprint [Phenotype and genotype of Clostridium sp. strains producing botulism neurotoxin]
    Ewa Augustynowicz
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 55:245-52. 2003

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Temporal nucleotide changes in pertactin and pertussis toxin genes in Bordetella pertussis strains isolated from clinical cases in Poland
    A Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, Chocimska Street 24, 00 791 Warsaw, Poland
    Vaccine 20:299-303. 2001
    ..pertussis in Poland and resulted in antigenic shift in both genes analyzed. Our findings may have implications for the composition of polish WCV and the currently licensed acellular pertussis vaccines...
  2. ncbi request reprint Amplified fragment length polymorphism (AFLP) versus randomly amplified polymorphic DNA (RAPD) as new tools for inter- and intra-species differentiation within Bordetella
    Anna Gzyl
    Department of Sera and Vaccine Evaluation, National Institute of Hygiene, 24 Chocimska Str, 00 791 Warsaw, Poland
    J Med Microbiol 54:333-46. 2005
    ....
  3. ncbi request reprint Potency of pertussis component in the DTP vaccine--an overview of three decade study in Poland
    Anna Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, Chocimska Str 24, 00 791 Warsaw, Poland
    Biologicals 32:129-37. 2004
    ..This might in turn explain the increase in pertussis cases among children aged 5-15 years which is presently being observed in Poland...
  4. ncbi request reprint [Genetic variability of Bordetella pertussis strains. Part I. Current knowledge]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 57:181-92. 2003
    ..Different ptxS1 and prn allele distribution for different countries needs further careful monitoring...
  5. ncbi request reprint [Genetic variability of Bordetella pertussis strains. Part II. Perspectives]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek Państwowego Zakładu Higieny ul Chocimska 24, 00 791 Warszawa
    Przegl Epidemiol 57:193-200. 2003
    ..pertussis strains harbouring different gene variants in a particular country might indicate a need for a change of B. pertussis strains used for production of the vaccine against pertussis...
  6. ncbi request reprint Sequence variation in pertussis S1 subunit toxin and pertussis genes in Bordetella pertussis strains used for the whole-cell pertussis vaccine produced in Poland since 1960: efficiency of the DTwP vaccine-induced immunity against currently circulating B.
    Anna Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, Chocimska Street 24, 00 791 Warsaw, Poland
    Vaccine 22:2122-8. 2004
    ..pertussis vaccine strains, since isolates with gene variants different from those observed in vaccine strains were eliminated from the lungs of the immunized animals with lower efficiency...
  7. ncbi request reprint Pertussis in Poland
    Anna Gzyl
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, 24 Chocimska Str, 00 791 Warsaw, Poland
    Int J Epidemiol 33:358-65. 2004
    ..The aim of the study was to analyse all available data on pertussis in Poland to identify the risks associated with its re-emergence...
  8. ncbi request reprint [Sources of information and knowledge on childhood immunisations among Polish parents]
    Justyna Rogalska
    Zakład Epidemiologii, Narodowego Instytutu Zdrowia Publicznego Państwowego Zakładu Higieny w Warszawie
    Przegl Epidemiol 64:83-90. 2010
    ..Poor knowledge on childhood immunisations among Polish parents needs to be addressed by improvement of reliable information on vaccines and vaccine safety...
  9. ncbi request reprint [Parental attitudes towards childhood immunisations in Poland]
    Justyna Rogalska
    Zakład Epidemiologii, Narodowego Instytutu Zdrowia Publicznego Państwowego Zakładu Higieny w Warszawie
    Przegl Epidemiol 64:91-7. 2010
    ..Systematic monitoring of parents' attitudes towards vaccination would help to address public health actions more adequately...
  10. ncbi request reprint [Phenotype and genotype of Clostridium sp. strains producing botulism neurotoxin]
    Ewa Augustynowicz
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 55:245-52. 2003
    ..Phenotype and genotype analysis indicated co-presence of B phenotype together with be genotype and A phenotype together with ae genotype among C. botulinum strains...
  11. ncbi request reprint Comparison of usefulness of randomly amplified polymorphic DNA and amplified-fragment length polymorphism techniques in epidemiological studies on nasopharyngeal carriage of non-typable Haemophilus influenzae
    Ewa Augustynowicz
    Department of Sera and Vaccine Evaluation, National Institute of Hygiene, Chocimska 24 St, 00 791 Warsaw, Poland
    J Med Microbiol 52:1005-14. 2003
    ..AFLP can efficiently access NTHI strain diversity and can monitor their turn-over for comparative typing in local and inter-local epidemiological investigations...
  12. ncbi request reprint Detection of enterotoxigenic Clostridium perfringens with a duplex PCR
    E Augustynowicz
    Department of Sera and Vaccines Evaluation, National Institute of Hygiene, Warsaw, Poland
    J Med Microbiol 51:169-72. 2002
    ..perfringens from vegetative cultures can be a useful tool as fresh isolates often sporulate poorly or not all, giving rise to the possibility of false negative results by serological analysis...
  13. pmc Bordetella pertussis strains circulating in Europe in 1999 to 2004 as determined by pulsed-field gel electrophoresis
    Hans Hallander
    Department of Immunology Vaccinology, Swedish Institute for Infectious Disease Control, Solna, Sweden
    J Clin Microbiol 45:3257-62. 2007
    ..It is therefore of major interest to continue with surveillance programs of B. pertussis isolates, as both waning vaccine-derived immunity and strain variation may play a role in the persistence of pertussis...
  14. ncbi request reprint [Occurrence of potentially invasive nontypeable Haemophilus influenzae strains isolating from children attending day-care centres and orphanages]
    Ewa Augustynowicz
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 59:103-12. 2007
    ..It has been shown, that potentially invasive NTHi strains appear with different frequency in day-care centres and orphanages. It also points out that dissemination NTHi is easy in such an environment...
  15. ncbi request reprint [Study of genetic diversity of nontypeable Haemophilus influenzae strains isolated from healthy children and patients with infection symptoms]
    Ewa Augustynowicz
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 59:113-22. 2007
    ..It has been shown that NTHi strains colonizing nasopharyngeal of healthy children present higher polymorphism level than strains isolated from patient with clinical symptoms of NTHi infection...
  16. ncbi request reprint [Evaluation of whole-cell and acellular pertussis vaccines effectiveness in clearance of experimental B. pertussis infection in mice]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 59:123-35. 2007
    ..The study indicated for lowered efficiency of whole-cell and acellular pertussis vaccines in elimination of mutated strains of B. pertussis from animal lung tissue in comparison with strains currently used for vaccine production...
  17. ncbi request reprint [Analysis of chosen parameters of immuno response in mice immunized with whole-cell or acellular pertussis vaccines and challenged with B. pertussis strains harbouring different ptxS1/prn allele genes combinations]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 59:137-47. 2007
    ..There were no quantitative differences of analysed factors involved in the immune response among mice challenged B. pertussis strains containing different ptxS1/prn composition...
  18. ncbi request reprint [Application of DNA microcarriers for evaluation of mice splenocytes genes expression after immunization with pertussis vaccines and challenged with different B. pertussis strains]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 59:149-59. 2007
    ..pertussis strains variant's for statistical evaluation of functional differences detected in presented study...
  19. ncbi request reprint [Study on genetic diversity of genes encoding main adhesins among nontypeable Haemophilus influenzae strains isolated from children in Poland]
    Ewa Augustynowicz
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 58:291-301. 2006
    ..Analysis of strains harbouring main adhesins profiles might be a useful screening method in monitoring strains circulating among children, in order to determine the most invasive NTHi strains...
  20. ncbi request reprint [Genetic diversity analysis of isolates belonging to Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica species]
    Ewa Mosiej
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 58:143-53. 2006
    ..pertussis strains. In case of B. bronchiseptica or B. parapertussis species-specific classification, SpeI/ApaI procedure has been found more precise than EcoRI/MseI one...
  21. ncbi request reprint [Genetic diversity analysis of isolates belonging to Bordetella genus]
    Ewa Mosiej
    Zakłład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 57:395-407. 2005
    ..bronchiseptica and B. hinzii isolates. Additionally RAPD method has been found to be useful for confirming B. avium and B. holmesii identification...
  22. ncbi request reprint [Diagnostic difficulties in identification of Haemophilus influenzae colonising the nasopharynx of children]
    Ewa Augustynowicz
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 57:29-37. 2005
    ..Due to perspectives of the wider use of Hib Immunisation in the future, more efficient diagnosis scheme for identification/differentiation of capsulated and non-capsulated H. influenzae strain should be undertaken...
  23. ncbi request reprint [Increase in the incidence of pertussis and quality of whole-cell pertussis component of the DTP vaccine produced in Poland. Part II. Consistency of control and production]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek PZH, Warszawa
    Przegl Epidemiol 58:641-8. 2004
    ..Obtained results showed high consistency of the production and control tests confirming relevant quality of country-produced DTP vaccine...
  24. ncbi request reprint [Immunity of children aged 6-8 against pertussis, tetanus and diphtheria]
    Janusz Slusarczyk
    Zakład Badania Surowic i Szczepionek, Państwowy Zakład Higieny, Warszawa
    Przegl Epidemiol 56:39-48. 2002
    ..Taking into consideration our results, it seems necessary to introduce additional dose of pertussis vaccine among children aged 5 years. The level of tetanus and diphtheria antibodies was high in all tested groups...
  25. ncbi request reprint Development of broad-range polymerase chain reaction (PCR) bacterial identification in diagnosis of infective endocarditis
    Tomasz Hryniewiecki
    National Institute of Cardiology, Warsaw, Poland
    J Heart Valve Dis 11:870-4. 2002
    ..The study aim was to identify the value of broad-range bacterial PCR in infective endocarditis (IE) of bacterial etiology, and to determine its specificity and sensitivity...
  26. ncbi request reprint [Increase in the incidence of pertussis and quality of whole-cell pertussis component of the DTP vaccine produced in Poland. Part I. Potency of DTP vaccine]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek PZH, Warszawa
    Przegl Epidemiol 58:629-39. 2004
    ..Additionally, the comparisons performed revealed a down trend in potency levels within 1992-1999 correlating to the lowering of the number of IOU/dose...
  27. ncbi request reprint [Transmission of Haemophilus influenzae type b strains among children attending day-care centers and orphanages]
    Ewa Augustynowicz
    Zakład Badania Surowic i Szczepionek PZH w Warszawie
    Med Dosw Mikrobiol 57:39-49. 2005
    ..Results obtained show that healthy children might be colonizing with genotypes characteristic for Hib strains isolated from invasive infections. In this view wider Hib vaccination seems be expected, as Hib circulation is common...
  28. ncbi request reprint [Broad-range fungal PCR in diagnosis of complicated infective endocarditis]
    Tomasz Hryniewiecki
    Klinika Wad Nabytych Serca Instytutu Kardiologii w Warszawie
    Pol Arch Med Wewn 108:941-6. 2002
    ..Amplification products were analyzed by gel electrophoresis. Fungal DNA was found in 2 patients with fungal super-infection of bacterial IE confirmed by culture. In the remaining patients with IE and controls no fungal DNA was found...
  29. ncbi request reprint [Laboratory assessment problems of the efficacy of acellular pertussis vaccines]
    Anna Gzyl
    Zakład Badania Surowic i Szczepionek Państwowego Zakładu Higieny, Warszawa
    Przegl Epidemiol 58:361-7. 2004
    ..g. Hib) both before and after conjugation. Mechanisms of interactions seen after conjugation inducing weaker immunogenicity or efficacy are still poorly recognized...