M M Dobrzyńska

Summary

Affiliation: National Institute of Hygiene
Country: Poland

Publications

  1. doi The effect of in vivo resveratrol supplementation in irradiated mice on the induction of micronuclei in peripheral blood and bone marrow reticulocytes
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health National Institute of Hygiene, 24 Chocimska Street, 00 791 Warsaw, Poland
    Mutagenesis 31:393-9. 2016
  2. doi Male-mediated F1 effects in mice exposed to bisphenol A, either alone or in combination with X-irradiation
    Małgorzata M Dobrzyńska
    National Institute of Public Health National Institute of Hygiene, Warsaw, Poland Electronic address
    Mutat Res Genet Toxicol Environ Mutagen 789:36-45. 2015
  3. doi DNA damage in organs of female and male mice exposed to nonylphenol, as a single agent or in combination with ionizing irradiation: a comet assay study
    Małgorzata M Dobrzyńska
    Department of Radiation Hygiene and Radiobiology, National Institute of Public Health National Institute of Hygiene, 24, Chocimska Str, 00 791 Warsaw, Poland Electronic address
    Mutat Res Genet Toxicol Environ Mutagen 772:14-9. 2014
  4. doi Genotoxicity of silver and titanium dioxide nanoparticles in bone marrow cells of rats in vivo
    Małgorzata M Dobrzyńska
    National Institute of Public Health National Institute of Hygiene, Warsaw, Poland Electronic address
    Toxicology 315:86-91. 2014
  5. ncbi [DNA damage to somatic cells of mice exposed to nonylphenol and to a combination of ionizing radiation and nonylphenol]
    Małgorzata M Dobrzyńska
    Zakład Higieny Radiacyjnej i Radiobiologii, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, Warszawa
    Rocz Panstw Zakl Hig 63:417-24. 2012
  6. doi Genotoxicity and reproductive toxicity of bisphenol A and X-ray/bisphenol A combination in male mice
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health National Institute of Hygiene, Warsaw, Poland
    Drug Chem Toxicol 36:19-26. 2013
  7. ncbi Two generation reproductive and developmental toxicity following subchronic exposure of pubescent male mice to di(2-ethylhexyl)phthalate
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health, Warsaw, Poland
    Ann Agric Environ Med 19:31-7. 2012
  8. ncbi [Frequency of micronuclei in reticulocytes of male mice exposed to bisphenol A and to a combination of x-rays and bisphenol A]
    Małgorzata M Dobrzyńska
    Zakład Ochrony Radiologicznej i Radiobiologii, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, Warszawa
    Rocz Panstw Zakl Hig 61:129-33. 2010
  9. ncbi [The effects of di-n-butyl phthalate on the somatic cells of laboratory mice]
    Małgorzata M Dobrzyńska
    Zakład Ochrony Radiologicznej i Radiobiologii, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, Warszawa
    Rocz Panstw Zakl Hig 61:13-9. 2010
  10. ncbi Is concentration and motility of male gametes related to DNA damage measured by comet assay?
    Malgorzata M Dobrzynska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health National Institute of Hygiene, Warsaw, Poland
    Ann Agric Environ Med 17:73-7. 2010

Detail Information

Publications19

  1. doi The effect of in vivo resveratrol supplementation in irradiated mice on the induction of micronuclei in peripheral blood and bone marrow reticulocytes
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health National Institute of Hygiene, 24 Chocimska Street, 00 791 Warsaw, Poland
    Mutagenesis 31:393-9. 2016
    ..RSV should be supplemented as soon as possible. Supplementation of RSV after termination of irradiation significantly speed up the recovery. Current results confirmed the ability of RSV to mitigate the effect of irradiation. ..
  2. doi Male-mediated F1 effects in mice exposed to bisphenol A, either alone or in combination with X-irradiation
    Małgorzata M Dobrzyńska
    National Institute of Public Health National Institute of Hygiene, Warsaw, Poland Electronic address
    Mutat Res Genet Toxicol Environ Mutagen 789:36-45. 2015
    ..Combined exposure induced two-fold higher postnatal mortality than BPA the alone, whereas BPA exposure caused reduced body weight and diminished sperm quality in F1 generation. ..
  3. doi DNA damage in organs of female and male mice exposed to nonylphenol, as a single agent or in combination with ionizing irradiation: a comet assay study
    Małgorzata M Dobrzyńska
    Department of Radiation Hygiene and Radiobiology, National Institute of Public Health National Institute of Hygiene, 24, Chocimska Str, 00 791 Warsaw, Poland Electronic address
    Mutat Res Genet Toxicol Environ Mutagen 772:14-9. 2014
    ..In contrast, in male mice, damage was reduced after combined irradiation-NP exposure, compared to NP alone...
  4. doi Genotoxicity of silver and titanium dioxide nanoparticles in bone marrow cells of rats in vivo
    Małgorzata M Dobrzyńska
    National Institute of Public Health National Institute of Hygiene, Warsaw, Poland Electronic address
    Toxicology 315:86-91. 2014
    ..The use of materials containing nanoparticles and the potential health implication of them should be monitored...
  5. ncbi [DNA damage to somatic cells of mice exposed to nonylphenol and to a combination of ionizing radiation and nonylphenol]
    Małgorzata M Dobrzyńska
    Zakład Higieny Radiacyjnej i Radiobiologii, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, Warszawa
    Rocz Panstw Zakl Hig 63:417-24. 2012
    ..Radiation comes from natural and man-made sources, and is used in medicine, science and industry. Both agents are widely present in environment, therefore human exposure to their combined effect seems to be highly probable...
  6. doi Genotoxicity and reproductive toxicity of bisphenol A and X-ray/bisphenol A combination in male mice
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health National Institute of Hygiene, Warsaw, Poland
    Drug Chem Toxicol 36:19-26. 2013
    ..Results confirmed the mutagenic ability of BPA. Combined exposure to X-rays and BPA leads to the prevention of DNA damage in somatic and germ cells of mice...
  7. ncbi Two generation reproductive and developmental toxicity following subchronic exposure of pubescent male mice to di(2-ethylhexyl)phthalate
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health, Warsaw, Poland
    Ann Agric Environ Med 19:31-7. 2012
    ..The results may suggest that diminished spermaozoa quality induced by DEHP may be coincidental with mutations leading to intrauterine deaths and skeletal abnormalities in the offspring...
  8. ncbi [Frequency of micronuclei in reticulocytes of male mice exposed to bisphenol A and to a combination of x-rays and bisphenol A]
    Małgorzata M Dobrzyńska
    Zakład Ochrony Radiologicznej i Radiobiologii, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, Warszawa
    Rocz Panstw Zakl Hig 61:129-33. 2010
    ..Ionising radiation is probably the agent which decided about damage and/or unequal distribution of chromosomes following combined exposure together with bisphenol A, which seems to be weak mutagen...
  9. ncbi [The effects of di-n-butyl phthalate on the somatic cells of laboratory mice]
    Małgorzata M Dobrzyńska
    Zakład Ochrony Radiologicznej i Radiobiologii, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, Warszawa
    Rocz Panstw Zakl Hig 61:13-9. 2010
    ..Results confirmed that DBP acts as a weak mutagen for DNA of somatic cells. However, following prolonged exposure this compound seems to undergo slower metabolism and was reaching temporarily higher levels in peripheral blood...
  10. ncbi Is concentration and motility of male gametes related to DNA damage measured by comet assay?
    Malgorzata M Dobrzynska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health National Institute of Hygiene, Warsaw, Poland
    Ann Agric Environ Med 17:73-7. 2010
    ..The highest DNA damage was noted in samples with low sperm concentration. In gametes from this group, the lowest percent of DNA in comet head, the highest mean tail length, and the highest tail moment were observed...
  11. ncbi Micronucleus formation induced by the combination of low doses of X-rays and antineoplastic drugs in bone marrow of male mice
    M M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Hygiene, Poland
    Teratog Carcinog Mutagen 20:321-7. 2000
    ..The combined treatment of X-rays and mitomycin C enhanced the mutagenic effect at 72 h. The combination of X-rays + vinblastine slightly potentiated the mutagenic effect at 24 h and 48 h...
  12. ncbi The effects in mice of combined treatments to X-rays and antineoplastic drugs in the Comet assay
    Małgorzata M Dobrzyńska
    National Institute of Hygiene, Department of Radiation Protection and Radiobiology, 24 Chocimska Street, 00 791 Warsaw, Poland
    Toxicology 207:331-8. 2005
    ..There were slightly different responses in bone marrow lymphocytes and in germ cells, but effects were observed over a similar dose range...
  13. ncbi Reproductive effects after exposure of male mice to vincristine and to a combination of X-rays and vincristine
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Hygiene, 24 Chocimska Street, 00 791 Warsaw, Poland
    Reprod Fertil Dev 17:759-67. 2005
    ..The results of this study demonstrated the reproductive genotoxicity of VCR with or without X-rays, but did not unequivocally confirm their ability to cause external malformations in offspring...
  14. ncbi Male-mediated developmental toxicity in mice after 8 weeks'exposure to low doses of X-rays
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Hygiene, Warsaw, Poland
    Int J Radiat Biol 81:793-9. 2005
    ..The aim of the study was to investigate the effects of subchronic irradiation of male mice on reproduction ability and induction of male-mediated teratogenesis...
  15. ncbi Assessment of DNA damage in multiple organs from mice exposed to X-rays or acrylamide or a combination of both using the comet assay
    Małgorzata Maria Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Hygiene, Warsaw, Poland
    In Vivo 21:657-62. 2007
    ..X-rays and acrylamide (AA) are present in the general environment and workplace and are potential hazards for human health. Combined exposure to both agents is possible, especially at low doses...
  16. ncbi [Frequency of micronuclei in erythrocytes of mice subchronic exposed to ionising radiation and nonylphenol]
    Małgorzata M Dobrzyńska
    Zakład Ochrony Radiologicznej i Radiobiologii, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, 00 791 Warszawa, ul Chocimska 24
    Rocz Panstw Zakl Hig 59:309-18. 2008
    ..05 Gy + 25 mg/kg bw NP) induced enhanced mutagenic effect. Contrary, after combined exposure to both agents in higher doses (0.10 Gy + 50 mg/kg bw NP), nonylphenol may protected DNA of reticulocytes against damage induced by X-rays...
  17. ncbi The effects of di-n-butyl phthalate on the germ cells of laboratory mice
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology National Institute of Public Health National Institute of Hygiene, Warsaw
    Rocz Panstw Zakl Hig 60:317-24. 2009
    ..There were no bioacumulation of DBP in mice. Results suggest that DBP may affect the male mice germ cells...
  18. ncbi Induction of micronuclei in bone marrow and sperm head abnormalities after combined exposure of mice to low doses of X-rays and acrylamide
    M M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Hygiene, Warsaw, Poland
    Teratog Carcinog Mutagen 20:133-40. 2000
    ..Combined exposure to 0.05 Gy + 75 mg/kg bw of AA induced micronuclei in polychromatic erythrocytes of bone marrow although each dose did not produce a mutagenic effect. Teratogenesis Carcinog. Mutagen. 20:133-140, 2000...
  19. doi Male-mediated F1 effects in mice exposed to nonylphenol or to a combination of X-rays and nonylphenol
    Małgorzata M Dobrzyńska
    Department of Radiation Protection and Radiobiology, National Institute of Public Health National Institute of Hygiene, Warsaw, Poland
    Drug Chem Toxicol 35:36-42. 2012
    ..Results showed that mutations induced in germ cells by subchronic exposure to NP and to combined X-ray/NP exposure may be transmitted to the F1 generation via sperm...