Roger Pique-Regi

Summary

Publications

  1. pmc Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 25:1223-30. 2009
  2. pmc R-Gada: a fast and flexible pipeline for copy number analysis in association studies
    Roger Pique-Regi
    Signal and Image Processing Institute, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    BMC Bioinformatics 11:380. 2010
  3. pmc Sparse representation and Bayesian detection of genome copy number alterations from microarray data
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 24:309-18. 2008
  4. pmc Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma
    Shahab Asgharzadeh
    Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
    J Clin Oncol 30:3525-32. 2012
  5. doi Bioinformatics for copy number variation data
    Melissa Warden
    Department of Pediatrics and Pathology, Keck School of Medicine, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA
    Methods Mol Biol 719:235-49. 2011
  6. pmc Copy number variation signature to predict human ancestry
    Melissa Pronold
    Department of Pediatrics, Children s Hospital Los Angeles and the Saban Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    BMC Bioinformatics 13:336. 2012
  7. ncbi Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification
    Shahab Asgharzadeh
    Department of Pediatrics, Division of Hematology Oncology, Childrens Hospital Los Angeles and Saban Research Institute, University of Southern California, Los Angeles, CA, USA
    J Natl Cancer Inst 98:1193-203. 2006

Detail Information

Publications7

  1. pmc Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 25:1223-30. 2009
    ..New approaches capable of jointly modeling the copy number and the non-copy number (noise) hybridization effects across multiple samples will potentially lead to more accurate results...
  2. pmc R-Gada: a fast and flexible pipeline for copy number analysis in association studies
    Roger Pique-Regi
    Signal and Image Processing Institute, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    BMC Bioinformatics 11:380. 2010
    ..CNVs have successfully provided target genome regions for some disease conditions where simple genetic variation (i.e., SNPs) has previously failed to provide a clear association...
  3. pmc Sparse representation and Bayesian detection of genome copy number alterations from microarray data
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 24:309-18. 2008
    ..This article proposes a novel detection technique that exploits the use of piece wise constant (PWC) vectors to represent genome copy number and sparse Bayesian learning (SBL) to detect CNA breakpoints...
  4. pmc Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma
    Shahab Asgharzadeh
    Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
    J Clin Oncol 30:3525-32. 2012
    ..In this study, we investigated the hypothesis that expression of genes related to tumor-associated inflammatory cells correlates with the observed differences in survival by age at diagnosis and contributes to a prognostic signature...
  5. doi Bioinformatics for copy number variation data
    Melissa Warden
    Department of Pediatrics and Pathology, Keck School of Medicine, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA
    Methods Mol Biol 719:235-49. 2011
    ..Here we describe a practical introduction to the copy number variation technology and available analysis methods, and demonstrate the analysis flow on an example case...
  6. pmc Copy number variation signature to predict human ancestry
    Melissa Pronold
    Department of Pediatrics, Children s Hospital Los Angeles and the Saban Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    BMC Bioinformatics 13:336. 2012
    ..Here we describe a simple and novel approach to locate genome-wide CNVs common to a specific population, using human ancestry as the phenotype...
  7. ncbi Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification
    Shahab Asgharzadeh
    Department of Pediatrics, Division of Hematology Oncology, Childrens Hospital Los Angeles and Saban Research Institute, University of Southern California, Los Angeles, CA, USA
    J Natl Cancer Inst 98:1193-203. 2006
    ..We examined whether molecular classification of metastatic neuroblastomas without MYCN gene amplification at diagnosis using gene expression profiling could improve the prediction of risk of disease progression...