Roman Pfeifer

Summary

Publications

  1. pmc Restricted duty hours for surgeons and impact on residents quality of life, education, and patient care: a literature review
    Hans Christoph Pape
    Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Kaufmann Medical Building, Suite 1010, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Patient Saf Surg 3:3. 2009
  2. doi request reprint Patterns of mortality and causes of death in polytrauma patients--has anything changed?
    Roman Pfeifer
    Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Kaufmann Medical Building, Pittsburgh, PA 15213, USA
    Injury 40:907-11. 2009
  3. pmc Socio-economic outcome after blunt orthopaedic trauma: Implications on injury prevention
    Roman Pfeifer
    University of Aachen Medical Center, Department of Orthopaedic Trauma, Pauwelsstrase 30, 52074 Aachen, Germany
    Patient Saf Surg 5:9. 2011
  4. ncbi request reprint Impact of isolated acetabular and lower extremity fractures on long-term outcome
    Roman Pfeifer
    Department of Orthopaedic Trauma, University of Aachen Medical Center, Pauwelstrasse 30, Aachen, Germany
    J Trauma Acute Care Surg 72:467-72. 2012
  5. pmc Trends in intubation rates and durations in ventilated severely injured trauma patients: an analysis from the TraumaRegister DGU®
    Khalid Almahmoud
    Department of Orthopedics Trauma Surgery, University of Aachen Medical Center, 52074 Aachen, Germany Harald Tscherne Laboratory, RWTH Aachen University, 52074 Aachen, Germany
    Patient Saf Surg 10:24. 2016
  6. pmc Cumulative effects of bone and soft tissue injury on systemic inflammation: a pilot study
    Roman Pfeifer
    Department of Orthopaedic Surgery, University of Aachen Medical Center, Pauwelsstr 30, 52074, Aachen, Germany
    Clin Orthop Relat Res 471:2815-21. 2013
  7. pmc Impact of Helicopter Emergency Medical Service in Traumatized Patients: Which Patient Benefits Most?
    Hagen Andruszkow
    Department of Orthopedic Trauma at Aachen University and Harald Tscherne Laboratory, University Hospital Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
    PLoS ONE 11:e0146897. 2016
  8. doi request reprint Post-traumatic thrombo-embolic complications in polytrauma patients
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, University Hospital Aachen, Pauwelsstrase 30, 52074, Aachen, Germany
    Int Orthop 39:947-54. 2015
  9. pmc MALP-2 pre-treatment modulates systemic inflammation in hemorrhagic shock
    Roman Pfeifer
    Department of Orthopaedic Trauma Surgery, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    J Inflamm (Lond) 10:17. 2013
  10. pmc Inducible nitric oxide synthase contributes to immune dysfunction following trauma
    Sophie S Darwiche
    Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Shock 38:499-507. 2012

Collaborators

Detail Information

Publications22

  1. pmc Restricted duty hours for surgeons and impact on residents quality of life, education, and patient care: a literature review
    Hans Christoph Pape
    Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Kaufmann Medical Building, Suite 1010, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Patient Saf Surg 3:3. 2009
    ..In this literature review, data of effects of limited work-hours on the quality of life, surgical education, and patient care was summarized, focusing on surgical subspecialities...
  2. doi request reprint Patterns of mortality and causes of death in polytrauma patients--has anything changed?
    Roman Pfeifer
    Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Kaufmann Medical Building, Pittsburgh, PA 15213, USA
    Injury 40:907-11. 2009
    ..Most of these studies have aimed to improve trauma care and raise awareness of avoidable complications. The aim of the present review is to evaluate whether the distribution of complications and mortality has changed...
  3. pmc Socio-economic outcome after blunt orthopaedic trauma: Implications on injury prevention
    Roman Pfeifer
    University of Aachen Medical Center, Department of Orthopaedic Trauma, Pauwelsstrase 30, 52074 Aachen, Germany
    Patient Saf Surg 5:9. 2011
    ..However, long-term social and economic implications have not been published so far. The aim of this investigation is to study the long-term socio-economic consequences of patients sustaining severe trauma...
  4. ncbi request reprint Impact of isolated acetabular and lower extremity fractures on long-term outcome
    Roman Pfeifer
    Department of Orthopaedic Trauma, University of Aachen Medical Center, Pauwelstrasse 30, Aachen, Germany
    J Trauma Acute Care Surg 72:467-72. 2012
    ..The long-term clinical status of surviving patients with multiple injuries has not been well described. The aim of this study was to evaluate the long-term outcome of acetabular and lower limb injuries...
  5. pmc Trends in intubation rates and durations in ventilated severely injured trauma patients: an analysis from the TraumaRegister DGU®
    Khalid Almahmoud
    Department of Orthopedics Trauma Surgery, University of Aachen Medical Center, 52074 Aachen, Germany Harald Tscherne Laboratory, RWTH Aachen University, 52074 Aachen, Germany
    Patient Saf Surg 10:24. 2016
    ....
  6. pmc Cumulative effects of bone and soft tissue injury on systemic inflammation: a pilot study
    Roman Pfeifer
    Department of Orthopaedic Surgery, University of Aachen Medical Center, Pauwelsstr 30, 52074, Aachen, Germany
    Clin Orthop Relat Res 471:2815-21. 2013
    ..However, it is unclear whether isolated bone or soft tissue injury contributes to the systemic inflammatory response and organ injury after fracture...
  7. pmc Impact of Helicopter Emergency Medical Service in Traumatized Patients: Which Patient Benefits Most?
    Hagen Andruszkow
    Department of Orthopedic Trauma at Aachen University and Harald Tscherne Laboratory, University Hospital Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
    PLoS ONE 11:e0146897. 2016
    ..However, it still remains unknown which group of trauma patients might benefit most from HEMS rescue. Consequently, the unique aim of this study was to reveal which patients might benefit most from HEMS rescue...
  8. doi request reprint Post-traumatic thrombo-embolic complications in polytrauma patients
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, University Hospital Aachen, Pauwelsstrase 30, 52074, Aachen, Germany
    Int Orthop 39:947-54. 2015
    ..Our aim was to determine the incidence of arterial and venous thrombo-embolic events (TE) in severely-injured trauma patients, and its associated risk factors by using a large trauma registry...
  9. pmc MALP-2 pre-treatment modulates systemic inflammation in hemorrhagic shock
    Roman Pfeifer
    Department of Orthopaedic Trauma Surgery, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    J Inflamm (Lond) 10:17. 2013
    ..In this experiment we investigated whether immunostimulation with TLR-2 agonists under conditions of sterile inflammation (hemorrhagic shock (HS)) may affect the immune response and remote organ inflammation...
  10. pmc Inducible nitric oxide synthase contributes to immune dysfunction following trauma
    Sophie S Darwiche
    Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Shock 38:499-507. 2012
    ..These findings support the hypothesis that iNOS regulates immune suppression following trauma and suggest that targeting the sustained production of NO by iNOS may attenuate posttraumatic immune depression...
  11. pmc Outcome after thoracoscopic ventral stabilisation of thoracic and lumbar spine fractures
    Roman Pfeifer
    Department of Orthopaedic and Trauma Surgery, University of Aachen Medical Center, 30 Pauwels Street, Aachen, 52074, Germany
    J Trauma Manag Outcomes 6:10. 2012
    ..However, there are a limited number of studies evaluating late clinical and radiological results after thoracoscopic spinal surgery...
  12. pmc Low back pain during pregnancy caused by a sacral stress fracture: a case report
    Miguel Pishnamaz
    Department of Orthopedic and Trauma Surgery, University of Aachen Medical Center, 30 Pauwels Street, 52074 Aachen, Germany
    J Med Case Rep 6:98. 2012
    ..This type of fracture has also been observed as a postpartum complication. To date, no cases of intrapartum sacral stress fractures have been described in the literature...
  13. pmc Inhalative IL-10 attenuates pulmonary inflammation following hemorrhagic shock without major alterations of the systemic inflammatory response
    Philipp Kobbe
    Department of Orthopaedic Trauma Surgery, Faculty of Medicine, RWTH Aachen University, Pauwelsstraβe 30, 52074 Aachen, Germany
    Mediators Inflamm 2012:512974. 2012
    ....
  14. doi request reprint Scoring systems for outcome after knee injuries
    Bernhard Schmidt-Rohlfing
    University of Aachen Medical Center, Department of Orthopaedic and Trauma Surgery, 30 Pauwels Street, 52074 Aachen, Germany
    Injury 42:271-5. 2011
    ..In conclusion, the outcomes of knee injuries in poly-traumatized patients are rather heterogeneous, but generally are worse than in those with lower extremity injuries that spare the knee joint...
  15. doi request reprint The timing of definitive fixation for major fractures in polytrauma--a matched-pair comparison between a US and European level I centres: analysis of current fracture management practice in polytrauma
    Verena M Schreiber
    Department of Orthopaedic Surgery, Division of Trauma, University of Pittsburgh, Pittsburgh, USA
    Injury 42:650-4. 2011
    ..The current study investigates whether the timing of fracture treatment is different in different trauma systems...
  16. pmc Impaired Fracture Healing after Hemorrhagic Shock
    Philipp Lichte
    Harald Tscherne Research Laboratory for Orthopedic Trauma, Department of Orthopaedic Trauma Surgery, University Hospital RWTH Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
    Mediators Inflamm 2015:132451. 2015
    ..This may be due to significantly diminished osteoclast recruitment. The exact mechanisms should be studied further, particularly during earlier stages of fracture healing. ..
  17. doi request reprint Do stable multiply injured patients with bilateral femur fractures have higher complication rates? An investigation by the EPOFF study group
    Roman Pfeifer
    Department of Orthopaedic Surgery, University of Aachen Medical Center, 30 Pauwels Street, 52074, Aachen, Germany
    Eur J Trauma Emerg Surg 38:185-90. 2012
    ..The current study tests the hypothesis that the high incidence of posttraumatic complications in patients who do not have a severe head or chest injury is caused by accompanying injuries rather than by the additional femur fracture...
  18. pmc Knowledge transfer of spinal manipulation skills by student-teachers: a randomised controlled trial
    Matthias Knobe
    Department of Orthopedic and Trauma Surgery, Medical Faculty, RWTH Aachen University, Pauwelsstrase 30, 52074 Aachen, Germany
    Eur Spine J 21:992-8. 2012
    ..To assess the use of peer-assisted learning (PAL) of complex manipulative motor skills with respect to gender in medical students...
  19. doi request reprint Predictors of late clinical outcome following orthopedic injuries after multiple trauma
    Hans Christoph Pape
    Department of Orthopaedic Trauma, University of Aachen Medical Center, Aachen, Germany
    J Trauma 69:1243-51. 2010
    ..The aim of this study was to evaluate whether certain injury patterns predispose a patient to a poor clinical outcome 10 or more years after multiple injuries...
  20. ncbi request reprint Induced Hypothermia Preserves the Functional Enterocyte Mass in A Porcine Multiple Trauma Model: Retracted
    Matthias Fröhlich
    Department of Orthopaedic Surgery, Traumatology and Sports Traumatology, Cologne Merheim Medical Centre CMMC, Witten Herdecke University, Ostmerheimer Str 200, D 51109 Cologne, Germany IFOM Institute for Research in Operative Medicine, Witten Herdecke University, Germany Department of Orthopaedic Trauma and Reconstructive Surgery, University Hospital Aachen, Germany Department of Orthopaedic Trauma Surgery, University of Schleswig Holstein, Kiel, Germany Trauma Department, Hannover Medical School, Germany Department of Orthopaedic Trauma Surgery, University of Magdeburg, Germany Department of Traumatology, Orthopaedic and Hand Surgery, Hospital Solingen, Germany Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria Department of Oral Biology, St James s University Hospital, University of Leeds, Leeds, UK Department of Experimental Trauma Surgery, Klinikum rechts der Isar, Technical University Munich, Ismaninger Strasse 22, 81675 Munich, Germany
    Shock . 2016
    ..As mild therapeutic hypothermia has been found to have protective effects on post-traumatic organ injuries, we analysed its effects on the intestine...
  21. pmc Models of lower extremity damage in mice: time course of organ damage and immune response
    Christoph L Menzel
    Department of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, USA
    J Surg Res 166:e149-56. 2011
    ..This follow-up study tests the hypothesis that inflammatory responses are comparable between a novel trauma model ("pseudofracture", PFx) and a bilateral femur fracture (BFF) model...
  22. pmc Missed injuries in trauma patients: A literature review
    Roman Pfeifer
    Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Kaufmann Medical Building, Suite 1010, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Patient Saf Surg 2:20. 2008
    ..This review summarizes the available literature on missed injuries, focusing on overlooked muscoloskeletal injuries...