Lili X Peng

Summary

Publications

  1. pmc Coarse-grained modeling study of nonpeptide RGD ligand density and PEG molecular weight on the conformation of poly(γ-glutamyl-glutamate) paclitaxel conjugates
    Lili X Peng
    Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA
    J Mol Model 17:2973-87. 2011
  2. doi Effects of solution concentration on the physicochemical properties of a polymeric anticancer therapeutic
    Lili X Peng
    Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, USA
    Mol Pharm 9:37-47. 2012
  3. pmc Characterization of a clinical polymer-drug conjugate using multiscale modeling
    Lili X Peng
    Department of Bioengineering, University of California, San Diego, CA, USA
    Biopolymers 93:936-51. 2010
  4. ncbi Aggregation properties of a polymeric anticancer therapeutic: a coarse-grained modeling study
    Lili X Peng
    Department of Bioengineering, Moores Cancer Center, University of California, San Diego, La Jolla, California
    J Chem Inf Model 51:3030-5. 2011

Detail Information

Publications4

  1. pmc Coarse-grained modeling study of nonpeptide RGD ligand density and PEG molecular weight on the conformation of poly(γ-glutamyl-glutamate) paclitaxel conjugates
    Lili X Peng
    Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA
    J Mol Model 17:2973-87. 2011
    ..These results indicate that the PGG-PTX-PEG1000-npRGD(4) and PGG-PTX-PEG1000-npRGD(8) molecules are the most efficacious candidates and are further recommended for experimental preclinical studies...
  2. doi Effects of solution concentration on the physicochemical properties of a polymeric anticancer therapeutic
    Lili X Peng
    Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, USA
    Mol Pharm 9:37-47. 2012
    ..This study demonstrates the practicality of molecular modeling toward understanding structural behavior of an anticancer therapeutic in different solution concentrations...
  3. pmc Characterization of a clinical polymer-drug conjugate using multiscale modeling
    Lili X Peng
    Department of Bioengineering, University of California, San Diego, CA, USA
    Biopolymers 93:936-51. 2010
    ..This multiscale modeling approach may be advantageous for the design of cancer therapeutic delivery systems. © 2010 Wiley Periodicals, Inc. Biopolymers 93: 936-951, 2010...
  4. ncbi Aggregation properties of a polymeric anticancer therapeutic: a coarse-grained modeling study
    Lili X Peng
    Department of Bioengineering, Moores Cancer Center, University of California, San Diego, La Jolla, California
    J Chem Inf Model 51:3030-5. 2011
    ..Overall, the f(PTX) = 0.37 'ends' and f(PTX) = 0.18 'even' PGG-PTX systems exhibit the highest aggregation and the 'middle' and 'side' systems the lowest...