Killian O'Rourke

Summary

Publications

  1. doi request reprint Phenotypic diversity associated with the mitochondrial m.8313G>A point mutation
    Killian O'Rourke
    Department of Neurology, St Vincent s University Hospital, Dublin 4, Ireland
    Muscle Nerve 40:648-51. 2009
  2. doi request reprint Impact of stroke units on mortality: a Bayesian analysis
    K O'Rourke
    Neurovascular Clinical Science Unit, Mater University Hospital, Dublin, Ireland
    Eur J Neurol 17:247-51. 2010
  3. doi request reprint Safety and efficacy of IV-TPA for ischaemic stroke in clinical practice--a Bayesian analysis
    Killian E T O'Rourke
    Stroke Service, Department of Neurology, and Neurovascular Clinical Science Unit, Mater University Hospital and University College Dublin, 1 Nelson Street, Dublin 7, Ireland
    Cerebrovasc Dis 28:572-81. 2009
  4. doi request reprint Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) in a sibling pair with a homozygous p.A467T POLG mutation
    John C McHugh
    Department of Neurology, St Vincent s University Hospital, Dublin, Ireland
    Muscle Nerve 41:265-9. 2010

Collaborators

Detail Information

Publications4

  1. doi request reprint Phenotypic diversity associated with the mitochondrial m.8313G>A point mutation
    Killian O'Rourke
    Department of Neurology, St Vincent s University Hospital, Dublin 4, Ireland
    Muscle Nerve 40:648-51. 2009
    ..This report of a second case, together with single muscle fiber mutation analysis that shows clear segregation of mutation load with cytochrome c oxidase deficiency, confirms that the mutation is pathologic...
  2. doi request reprint Impact of stroke units on mortality: a Bayesian analysis
    K O'Rourke
    Neurovascular Clinical Science Unit, Mater University Hospital, Dublin, Ireland
    Eur J Neurol 17:247-51. 2010
    ..Observational studies of the impact of care delivered in stroke units on mortality after acute stroke have been difficult to interpret because of bias...
  3. doi request reprint Safety and efficacy of IV-TPA for ischaemic stroke in clinical practice--a Bayesian analysis
    Killian E T O'Rourke
    Stroke Service, Department of Neurology, and Neurovascular Clinical Science Unit, Mater University Hospital and University College Dublin, 1 Nelson Street, Dublin 7, Ireland
    Cerebrovasc Dis 28:572-81. 2009
    ..We used a Bayesian approach to interpret and sequentially combine phase 4 studies of IV-TPA within 3 h for acute ischaemic stroke to quantify the cumulative evidence for the efficacy and safety of this therapy in clinical practice...
  4. doi request reprint Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) in a sibling pair with a homozygous p.A467T POLG mutation
    John C McHugh
    Department of Neurology, St Vincent s University Hospital, Dublin, Ireland
    Muscle Nerve 41:265-9. 2010
    ..The enlarging spectrum of sensory ataxic neuropathies associated with mitochondrial DNA (mtDNA) instability and POLG mutations should be recognized and considered in the differential diagnosis of this unusual presentation...