Arnfinn Sundsfjord

Summary

Affiliation: University of Troms
Country: Norway

Publications

  1. ncbi request reprint Human infections caused by glycopeptide-resistant Enterococcus spp: are they a zoonosis?
    A Sundsfjord
    Unite des Agents Antibacteriens, Institut Pasteur, Paris, France
    Clin Microbiol Infect 7:16-33. 2001
  2. ncbi request reprint [Antimicrobial resistance after antibiotic use in animals--impact on human health]
    Arnfinn Sundsfjord
    Avdeling for mikrobiologi og virologi Institutt for medisinsk biologi Det medisinske fakultet Universitetet i Tromsø 9037 Tromsø
    Tidsskr Nor Laegeforen 128:2457-61. 2008
  3. ncbi request reprint [Broad-spectrum beta-lactamases in Gram-negative bacteria]
    Arnfinn Sundsfjord
    Avdeling for mikrobiologi og virologi Institutt for medisinsk biologi Det medisinske fakultet Universitetet i Tromsø 9037 Tromsø
    Tidsskr Nor Laegeforen 128:2741-5. 2008
  4. ncbi request reprint Genetic methods for detection of antimicrobial resistance
    Arnfinn Sundsfjord
    Department of Microbiology and Virology, University of Tromsø, Norway
    APMIS 112:815-37. 2004
  5. doi request reprint PCR-based plasmid typing in Enterococcus faecium strains reveals widely distributed pRE25-, pRUM-, pIP501- and pHTbeta-related replicons associated with glycopeptide resistance and stabilizing toxin-antitoxin systems
    Torill C S Rosvoll
    Department of Medical Biology, University of Tromsø, Tromsø, Norway
    FEMS Immunol Med Microbiol 58:254-68. 2010
  6. doi request reprint Species identification and molecular characterization of Acinetobacter spp. blood culture isolates from Norway
    Nabil Karah
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, and Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    J Antimicrob Chemother 66:738-44. 2011
  7. pmc ICESluvan, a 94-kilobase mosaic integrative conjugative element conferring interspecies transfer of VanB-type glycopeptide resistance, a novel bacitracin resistance locus, and a toxin-antitoxin stabilization system
    Eva K Bjørkeng
    Research Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    J Bacteriol 195:5381-90. 2013
  8. ncbi request reprint mef(A), mef(E) and a new mef allele in macrolide-resistant Streptococcus spp. isolates from Norway
    Maria Sangvik
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology, University Hospital of North Norway, University of Tromsø, N 9037 Tromsø, Norway
    J Antimicrob Chemother 56:841-6. 2005
  9. doi request reprint Clustering of polyclonal VanB-type vancomycin-resistant Enterococcus faecium in a low-endemic area was associated with CC17-genogroup strains harbouring transferable vanB2-Tn5382 and pRUM-like repA containing plasmids with axe-txe plasmid addiction system
    Eva Bjørkeng
    Research Group for Host Microbe Interactions, Department of Medical Biology, University of Tromsø, Norway
    APMIS 119:247-58. 2011
  10. pmc Transferable vanB2 Tn5382-containing elements in fecal streptococcal strains from veal calves
    Kristin H Dahl
    Department of Microbiology and Virology, University of Tromsø, Norway
    Antimicrob Agents Chemother 47:2579-83. 2003

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Human infections caused by glycopeptide-resistant Enterococcus spp: are they a zoonosis?
    A Sundsfjord
    Unite des Agents Antibacteriens, Institut Pasteur, Paris, France
    Clin Microbiol Infect 7:16-33. 2001
    ....
  2. ncbi request reprint [Antimicrobial resistance after antibiotic use in animals--impact on human health]
    Arnfinn Sundsfjord
    Avdeling for mikrobiologi og virologi Institutt for medisinsk biologi Det medisinske fakultet Universitetet i Tromsø 9037 Tromsø
    Tidsskr Nor Laegeforen 128:2457-61. 2008
    ..The clinically most important resistance problems in human medicine that are associated with antimicrobial resistance in animals, are discussed in a global perspective...
  3. ncbi request reprint [Broad-spectrum beta-lactamases in Gram-negative bacteria]
    Arnfinn Sundsfjord
    Avdeling for mikrobiologi og virologi Institutt for medisinsk biologi Det medisinske fakultet Universitetet i Tromsø 9037 Tromsø
    Tidsskr Nor Laegeforen 128:2741-5. 2008
    ..Resistance towards them, in both Gram-positive and Gram-negative bacteria, challenges their antimicrobial effect. beta-lactamases are the most important resistance mechanism against beta-lactams in Gram-negative bacteria...
  4. ncbi request reprint Genetic methods for detection of antimicrobial resistance
    Arnfinn Sundsfjord
    Department of Microbiology and Virology, University of Tromsø, Norway
    APMIS 112:815-37. 2004
    ....
  5. doi request reprint PCR-based plasmid typing in Enterococcus faecium strains reveals widely distributed pRE25-, pRUM-, pIP501- and pHTbeta-related replicons associated with glycopeptide resistance and stabilizing toxin-antitoxin systems
    Torill C S Rosvoll
    Department of Medical Biology, University of Tromsø, Tromsø, Norway
    FEMS Immunol Med Microbiol 58:254-68. 2010
    ..PCR-based replicon typing, linked to the detection of other important plasmid-encoded traits, seems to be a feasible tool for tracing disseminating resistance plasmids stably maintained in various environments...
  6. doi request reprint Species identification and molecular characterization of Acinetobacter spp. blood culture isolates from Norway
    Nabil Karah
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, and Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    J Antimicrob Chemother 66:738-44. 2011
    ....
  7. pmc ICESluvan, a 94-kilobase mosaic integrative conjugative element conferring interspecies transfer of VanB-type glycopeptide resistance, a novel bacitracin resistance locus, and a toxin-antitoxin stabilization system
    Eva K Bjørkeng
    Research Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    J Bacteriol 195:5381-90. 2013
    ..Sequence analysis of the original S. lutetiensis donor and enterococcal transconjugants showed that ICESluvan integrates in a site-specific manner into the C-terminal end of the chromosomal tRNA methyltransferase gene rumA. ..
  8. ncbi request reprint mef(A), mef(E) and a new mef allele in macrolide-resistant Streptococcus spp. isolates from Norway
    Maria Sangvik
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology, University Hospital of North Norway, University of Tromsø, N 9037 Tromsø, Norway
    J Antimicrob Chemother 56:841-6. 2005
    ..To type mef genes in a nationwide collection of clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes as well as pharyngeal carrier strains of viridans streptococci in Norway...
  9. doi request reprint Clustering of polyclonal VanB-type vancomycin-resistant Enterococcus faecium in a low-endemic area was associated with CC17-genogroup strains harbouring transferable vanB2-Tn5382 and pRUM-like repA containing plasmids with axe-txe plasmid addiction system
    Eva Bjørkeng
    Research Group for Host Microbe Interactions, Department of Medical Biology, University of Tromsø, Norway
    APMIS 119:247-58. 2011
    ..Our observations support the notion that vanB-type vancomycin-resistant Enterococcus faecium can persist in a low-endemic area through successful clones and plasmids with stability functions in hospital patients with known risk factors...
  10. pmc Transferable vanB2 Tn5382-containing elements in fecal streptococcal strains from veal calves
    Kristin H Dahl
    Department of Microbiology and Virology, University of Tromsø, Norway
    Antimicrob Agents Chemother 47:2579-83. 2003
    ....
  11. ncbi request reprint Transfer of plasmid and chromosomal glycopeptide resistance determinants occurs more readily in the digestive tract of mice than in vitro and exconjugants can persist stably in vivo in the absence of glycopeptide selection
    Kristin Hegstad Dahl
    Department of Microbiology and Virology, University of Tromsø, Tromsø, Norway
    J Antimicrob Chemother 59:478-86. 2007
    ..Moreover, the stability of exconjugants in vivo in the absence of antibiotic selection was examined...
  12. doi request reprint Increased high-level gentamicin resistance in invasive Enterococcus faecium is associated with aac(6')Ie-aph(2″)Ia-encoding transferable megaplasmids hosted by major hospital-adapted lineages
    Torill C S Rosvoll
    Research Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    FEMS Immunol Med Microbiol 66:166-76. 2012
    ..faecium. In conclusion, the increased prevalence of HLGR in invasive E. faecium in Norway is associated with hospital-adapted genetic lineages carrying aac(6')-Ie-aph(2″)-Ia-encoding transferable megaplasmids of the pLG1 replicon type...
  13. doi request reprint Fecal colonization of VIM-1-producing Klebsiella pneumoniae and in vivo transfer of multidrug-resistant IncN plasmid in a renal transplant patient
    Umaer Naseer
    Research Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, 9038 Tromsø, Norway
    Diagn Microbiol Infect Dis 72:363-6. 2012
    ....
  14. pmc Occurrence, population structure, and antimicrobial resistance of enterococci in marginal and apical periodontitis
    Jinglu Sun
    Department of Medical Biology, Medical Faculty, University of Tromsø, Tromsø, Norway
    J Clin Microbiol 47:2218-25. 2009
    ..faecalis might represent a reservoir of resistance to tetracycline and erythromycin. The subgingival E. faecalis isolates show high genetic diversity but are grouped, in general, with the known isolates from the international database...
  15. pmc Characterisation of the plasmidome within Enterococcus faecalis isolated from marginal periodontitis patients in Norway
    Xiaobo Song
    Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    PLoS ONE 8:e62248. 2013
    ..The results indicate that the majority of E. faecalis of marginal periodontitis are likely to be a reservoir for diverse mobile genetic elements and associated antimicrobial resistance determinants...
  16. doi request reprint Factors affecting the reversal of antimicrobial-drug resistance
    Pål J Johnsen
    Department of Pharmacy, Faculty of Medicine, University of Tromsø, Tromsø, Norway
    Lancet Infect Dis 9:357-64. 2009
    ..Resistance determinants may persist at low, but detectable, levels for many years in the absence of the corresponding drugs...
  17. doi request reprint Emergence of OXA-carbapenemase- and 16S rRNA methylase-producing international clones of Acinetobacter baumannii in Norway
    Nabil Karah
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, and Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    J Med Microbiol 60:515-21. 2011
    ..baumannii isolates producing OXA carbapenemase and 16S rRNA methylase in Norway was related to the worldwide distribution of international clones I and II, and the emergence of novel international clones...
  18. pmc ccrABEnt serine recombinase genes are widely distributed in the Enterococcus faecium and Enterococcus casseliflavus species groups and are expressed in E. faecium
    Eva Katrin Bjørkeng
    Research Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, N 9037 Tromsø, Norway
    Microbiology 156:3624-34. 2010
    ..faecium. In summary, ccrAB(Ent) genes, potentially involved in genome plasticity, are expressed in E. faecium and are widely distributed in the E. faecium and E. casseliflavus species groups...
  19. pmc Multi-locus variable number of tandem repeat analysis for rapid and accurate typing of virulent multidrug resistant Escherichia coli clones
    Umaer Naseer
    Research Group for Host Microbe Interactions, Department of Medical Biology, University of Tromsø, Tromsø, Norway
    PLoS ONE 7:e41232. 2012
    ..MLVA is a rapid and accurate tool for genotyping isolates of globally disseminated virulent multidrug resistant E. coli lineages, including ST131...
  20. ncbi request reprint Stability, persistence, and evolution of plasmid-encoded VanA glycopeptide resistance in enterococci in the absence of antibiotic selection in vitro and in gnotobiotic mice
    Pål J Johnsen
    Department of Microbiology and Virology, University and University Hospital of Tromsø, Norway
    Microb Drug Resist 8:161-70. 2002
    ....
  21. ncbi request reprint Nosocomial outbreak of CTX-M-15-producing E. coli in Norway
    Umaer Naseer
    Reference Centre for Detection of Antimicrobial Resistance K res, Department of Microbiology and Infection Control, University Hospital of Northern Norway, Norway
    APMIS 115:120-6. 2007
    ..The outbreak emphasises the epidemic potential of multiple-antibiotic-resistant CTX-M-15-producing E. coli also in a country with low antibiotic usage and low prevalence of antimicrobial resistance...
  22. doi request reprint Molecular characterization of CTX-M-15-producing clinical isolates of Escherichia coli reveals the spread of multidrug-resistant ST131 (O25:H4) and ST964 (O102:H6) strains in Norway
    Umaer Naseer
    Reference Centre for Detection of Antimicrobial Resistance K res, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway
    APMIS 117:526-36. 2009
    ..This study reveals that the majority of CTX-M-15-expressing strains in Norway are part of the global spread of multidrug-resistant ST131 and ST-complex 405, associated with ISEcp1 on transferrable IncFII plasmids...
  23. doi request reprint The CTX-M conundrum: dissemination of plasmids and Escherichia coli clones
    Umaer Naseer
    Research Group for Host Microbe Interactions, Department of Medical Biology, University of Tromsø, Tromsø, Norway
    Microb Drug Resist 17:83-97. 2011
    ..Thus, we are witnessing a global epidemic of bla(CTX-M)-encoding E. coli strains and plasmids, which require serious attention and efficient infection control measures...
  24. doi request reprint Structural and computational investigations of VIM-7: insights into the substrate specificity of vim metallo-β-lactamases
    Pardha Saradhi Borra
    Research Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
    J Mol Biol 411:174-89. 2011
    ..Our structures thus provide new insights into the variation in substrate specificity that is evident across this family of clinically important enzymes...
  25. pmc Nonconjugative transposition of the vanB-containing Tn5382-like element in Enterococcus faecium
    Kristin H Dahl
    Department of Microbiology and Virology, University and University Hospital of Tromsø Norwegian Institute of Gene Ecology, Tromsø, Norway
    Antimicrob Agents Chemother 47:786-9. 2003
    ..Conjugative transposition of the Tn5382-like element was not demonstrated in retransfer studies...
  26. ncbi request reprint Phenotypic and genotypic aminoglycoside resistance in blood culture isolates of coagulase-negative staphylococci from a single neonatal intensive care unit, 1989-2000
    Claus Klingenberg
    Department of Paediatrics, University Hospital of North Norway, N 9038 Tromsø
    J Antimicrob Chemother 54:889-96. 2004
    ..To investigate the prevalence of aminoglycoside resistance and genes encoding aminoglycoside-modifying enzymes (AME) in blood culture isolates of coagulase-negative staphylococci (CoNS) from neonates...
  27. ncbi request reprint Molecular detection of antibiotic resistance: when and where?
    Neil Woodford
    Antibiotic Resistance Monitoring and Reference Laboratory, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    J Antimicrob Chemother 56:259-61. 2005
    ....
  28. pmc Clonal spread of macrolide- and tetracycline-resistant [erm(A) tet(O)] emm77 Streptococcus pyogenes isolates in Italy and Norway
    Claudio Palmieri
    Antimicrob Agents Chemother 50:4229-30. 2006
  29. doi request reprint The AmpC phenotype in Norwegian clinical isolates of Escherichia coli is associated with an acquired ISEcp1-like ampC element or hyperproduction of the endogenous AmpC
    Bjørg Haldorsen
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway
    J Antimicrob Chemother 62:694-702. 2008
    ..The aim of the study was to examine resistance mechanisms associated with an AmpC phenotype in Norwegian clinical isolates of Escherichia coli...
  30. doi request reprint Evaluation of phenotypic tests for the detection of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a low prevalence country
    Orjan Samuelsen
    Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway
    J Antimicrob Chemother 61:827-30. 2008
    ..To evaluate four phenotypic tests for the detection of metallo-beta-lactamase (MBL) production in Pseudomonas aeruginosa in a low MBL prevalence setting...
  31. pmc Effects of phenotype and genotype on methods for detection of extended-spectrum-beta-lactamase-producing clinical isolates of Escherichia coli and Klebsiella pneumoniae in Norway
    Ståle Tofteland
    Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway
    J Clin Microbiol 45:199-205. 2007
    ..coli strains. The relatively high proportion of ESBL-producing E. coli organisms with a low ceftazidime MIC in Norway emphasizes that cefpodoxime alone or both cefotaxime and ceftazidime should be used as substrates for ESBL detection...
  32. ncbi request reprint [Is the last bastion falling down?]
    Arnfinn Sundsfjord
    Tidsskr Nor Laegeforen 122:2179. 2002
  33. doi request reprint Alterations of porin, pumps, and penicillin-binding proteins in carbapenem resistant clinical isolates of Pseudomonas aeruginosa
    Christian G Giske
    Department of Clinical Microbiology, Karolinska Institutet MTC, Karolinska University Hospital Solna, Stockholm, Sweden
    Microb Drug Resist 14:23-30. 2008
    ..Reduced transcription of pbp 2 and 3 may contribute to the carbapenem resistance...