E W Nielsen

Summary

Affiliation: University of Troms
Country: Norway

Publications

  1. ncbi request reprint [Rescue helicopter service in Bodö--advanced emergency service or alternative transportation?]
    Atle Ulvik
    Anestesiavdelingen Nordland Sentralsykehus 8092 Bodø
    Tidsskr Nor Laegeforen 122:25-9. 2002
  2. ncbi request reprint [A 71-year-old man with Cushing reflex]
    Erik Waage Nielsen
    Anestesiavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 124:943-5. 2004
  3. pmc 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
    Tom Bowen
    Departments of Medicine and Paediatrics, University of Calgary, Calgary, Alberta, Canada
    Allergy Asthma Clin Immunol 6:24. 2010
  4. ncbi request reprint Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement
    Erik Waage Nielsen
    Department of Anesthesiology, Nordland Hospital, N 8092 Bodø, Norway University of Tromsø, Norway
    Mol Immunol 44:1819-26. 2007
  5. ncbi request reprint Angioedema from angiotensin-converting enzyme (ACE) inhibitor treated with complement 1 (C1) inhibitor concentrate
    E W Nielsen
    Department of Anesthesiology, Nordland Hospital and University of Tromsø, Tromsø, Norway
    Acta Anaesthesiol Scand 50:120-2. 2006
  6. ncbi request reprint Hypotensive shock and angio-oedema from angiotensin II receptor blocker: a class effect in spite of tripled tryptase values
    E W Nielsen
    Department of Anaesthesiology, Nordland Hospital, Bodø and University of Tromsø, Tromsø, Norway
    J Intern Med 258:385-7. 2005
  7. ncbi request reprint [Let the air out!]
    Erik Waage Nielsen
    Anestesiavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 125:1186. 2005
  8. ncbi request reprint [Drug interactions in an intensive care unit]
    Erik Waage Nielsen
    Anestesi og Intensivavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 124:2907-8. 2004
  9. doi request reprint A new dynamic porcine model of meningococcal shock
    Erik Waage Nielsen
    Department of Anesthesiology, Norland Hospital, Bodø, Norway
    Shock 32:302-9. 2009
  10. ncbi request reprint C1-inhibitor reduces the ischaemia-reperfusion injury of skeletal muscles in mice after aortic cross-clamping
    E W Nielsen
    University of Tromsø and Nordland Hospital, Bodø, Norway
    Scand J Immunol 56:588-92. 2002

Collaborators

Detail Information

Publications27

  1. ncbi request reprint [Rescue helicopter service in Bodö--advanced emergency service or alternative transportation?]
    Atle Ulvik
    Anestesiavdelingen Nordland Sentralsykehus 8092 Bodø
    Tidsskr Nor Laegeforen 122:25-9. 2002
    ..An increase in fatal accidents in helicopter ambulance missions in Norway has put focus on the guidelines for use...
  2. ncbi request reprint [A 71-year-old man with Cushing reflex]
    Erik Waage Nielsen
    Anestesiavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 124:943-5. 2004
    ..The Cushing reflex in comatose intensive care patients usually indicates that intracranial perfusion is about to be abolished...
  3. pmc 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
    Tom Bowen
    Departments of Medicine and Paediatrics, University of Calgary, Calgary, Alberta, Canada
    Allergy Asthma Clin Immunol 6:24. 2010
    ....
  4. ncbi request reprint Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement
    Erik Waage Nielsen
    Department of Anesthesiology, Nordland Hospital, N 8092 Bodø, Norway University of Tromsø, Norway
    Mol Immunol 44:1819-26. 2007
    ..Previous studies interpreting the effects of C1-inhibitor as only due to classical pathway inhibition needs reconsideration. The data has implications for the therapeutic use of C1-inhibitor...
  5. ncbi request reprint Angioedema from angiotensin-converting enzyme (ACE) inhibitor treated with complement 1 (C1) inhibitor concentrate
    E W Nielsen
    Department of Anesthesiology, Nordland Hospital and University of Tromsø, Tromsø, Norway
    Acta Anaesthesiol Scand 50:120-2. 2006
    ..Up to seven in every 1000 patients experience angioedema from angiotensin-converting enzyme (ACE) inhibitors, even after many years of use. In 2003, every 20th Norwegian used an ACE inhibitor...
  6. ncbi request reprint Hypotensive shock and angio-oedema from angiotensin II receptor blocker: a class effect in spite of tripled tryptase values
    E W Nielsen
    Department of Anaesthesiology, Nordland Hospital, Bodø and University of Tromsø, Tromsø, Norway
    J Intern Med 258:385-7. 2005
    ..To our knowledge, our report is one of the first on shock and angio-oedema from irbesartan...
  7. ncbi request reprint [Let the air out!]
    Erik Waage Nielsen
    Anestesiavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 125:1186. 2005
  8. ncbi request reprint [Drug interactions in an intensive care unit]
    Erik Waage Nielsen
    Anestesi og Intensivavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 124:2907-8. 2004
    ..druid.uio.no and in some computer physician order entry systems. The scope of this paper was to assess drug use and examine the potential usefulness of DRUID in an intensive care unit...
  9. doi request reprint A new dynamic porcine model of meningococcal shock
    Erik Waage Nielsen
    Department of Anesthesiology, Norland Hospital, Bodø, Norway
    Shock 32:302-9. 2009
    ..This is the first large animal model of sepsis using whole Neisseria meningitidis. The model simulates well central aspects of human meningococcal sepsis and could be used for future interventional studies...
  10. ncbi request reprint C1-inhibitor reduces the ischaemia-reperfusion injury of skeletal muscles in mice after aortic cross-clamping
    E W Nielsen
    University of Tromsø and Nordland Hospital, Bodø, Norway
    Scand J Immunol 56:588-92. 2002
    ....
  11. ncbi request reprint When is an anesthesiologist needed in a helicopter emergency medical service in northern Norway?
    E W Nielsen
    Department of Anesthesiology, Nordland Central Hospital, Bodø and University of Tromsø, Norway
    Acta Anaesthesiol Scand 46:785-8. 2002
    ..Our aim was to assess what proportion of ambulance missions carried out by the rescue helicopter in Bodø, northern Norway, delivered advanced medical treatment needing the skills of an anesthesiologist...
  12. pmc C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood
    A Landsem
    Department of Laboratory Medicine, Nordland Hospital, Bodø, Norway
    Clin Exp Immunol 173:217-29. 2013
    ..These results indicate that complement plays a role in activating coagulation during sepsis and that C1-INH is a broad-spectrum attenuator of the inflammatory and haemostatic responses...
  13. ncbi request reprint The effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upregulation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood
    O L Brekke
    Department of Laboratory Medicine, Nordland Hospital, Bodø, N 8092, Norway
    Adv Exp Med Biol 735:123-36. 2013
    ..coli-induced tissue factor (TF) mRNA upregulation, expression by monocytes, and functional activity in human whole blood...
  14. pmc The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood
    A Landsem
    Research Laboratory and Department of Laboratory Medicine, Nordland Hospital, Bodø, Norway
    Clin Exp Immunol 182:81-9. 2015
    ..coli-induced PTF1.2 was reduced by 76-81% (P < 0·05) with anti-TF antibody. LPS and E. coli activated the coagulation system by a complement- and CD14-dependent up-regulation of TF, leading subsequently to prothrombin activation...
  15. doi request reprint C1-inhibitor efficiently delays clot development in normal human whole blood and inhibits Escherichia coli-induced coagulation measured by thromboelastometry
    A Landsem
    Research Laboratory, Nordland Hospital, Bodø, Norway Institute of Clinical Medicine, University of Tromsø The Arctic University of Norway, Tromsø, Norway Electronic address
    Thromb Res 143:63-70. 2016
    ..However, previous reports indicate thrombotic risks in children following supraphysiological dosing with C1-INH...
  16. pmc Systemic inflammation in acute intermittent porphyria: A case control study
    E Storjord
    Department of Laboratory Medicine, Nordland Hospital, Bodø, Norway
    Clin Exp Immunol . 2016
    ..Decreased C-peptide levels in symptomatic AIP cases indicate that reduced insulin release is associated with enhanced disease activity and reduced kidney function. This article is protected by copyright. All rights reserved...
  17. ncbi request reprint The Effects of Selective Complement and CD14 Inhibition on the E. coli-Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood
    O L Brekke
    Department of Laboratory Medicine, Nordland Hospital, Bodø, N 8092, Norway
    Adv Exp Med Biol 734:123-36. 2013
    ..Conclusion: Our results indicate that E. coli-induced TF mRNA upregulation is mainly dependent on complement activation, while CD14 plays a modest role in monocyte TF expression and the plasma TF activity in human whole blood...
  18. ncbi request reprint Expression of active human C1 inhibitor serpin domain in Escherichia coli
    T Lamark
    Institute of Pharmacy, University of Tromsø, Tromsø, 9037, Norway
    Protein Expr Purif 22:349-58. 2001
    ..However, a major obstacle to large-scale production will be to produce the protein in a soluble form. Attempts to increase the yield of soluble protein by coexpression of the GroEL/ES chaperonins resulted in an increase in solubility...
  19. pmc A young man with acute dilated cardiomyopathy associated with methylphenidate
    Tor Bjarne Nymark
    Section for Emergency Medicine, Nordland Hospital, Bodø, Norway
    Vasc Health Risk Manag 4:477-9. 2008
    ..EF at this point was 15%. The patient was denied heart transplantation due to various cofactors. The investigation concluded with a probable relationship between his cardiomyopathy and the use of methylphenidate (Concerta)...
  20. pmc Why does the provision of home mechanical ventilation vary so widely?
    Knut Dybwik
    Intensive Care Unit, Department of Anesthesiology, Nordland Hospital, Bodø, Norway
    Chron Respir Dis 7:67-73. 2010
    ..Data describing regional differences in the prevalence of HMV within countries is lacking. Further research is needed to identify these differences to ensure equality of provision of HMV...
  21. ncbi request reprint [A new tool for retrieving clinical data from various sources]
    Erik Waage Nielsen
    Anestesi og Intensivavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 126:605-7. 2006
    ..A doctor's tool for extracting clinical data from various sources on groups of hospital patients into one file has been in demand. For this purpose we evaluated Qlikview...
  22. pmc Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature
    Knut Tore Lappegard
    Department of Medicine, Nordland Hospital, Bodø, and University of Tromsø, Norway
    Proc Natl Acad Sci U S A 106:15861-6. 2009
    ..Notably, all responses were abolished by combined neutralization of complement and CD14. The present study provides important insight into the comprehensive role of complement in human inflammatory responses to gram-negative bacteria...
  23. ncbi request reprint [A 6-week-old boy with pneumonia and extreme leucocytosis]
    David Nystad
    Akuttmedisinsk avdeling, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 128:938-9. 2008
  24. ncbi request reprint [Loss of weight and acute abdominal pain in a 38-year-old psychostimulant abuser]
    Tor Bjarne Nymark
    Anestesiavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 127:299-300. 2007
    ..The patient died. At autopsy the coeliac trunk was compressed by thrombi in a dissecting space. A dissection was also found from the proximal aorta to the common iliac arteries. The heart was hypertrophic and weighed 640 g...
  25. ncbi request reprint Hereditary and acquired angioedema: problems and progress: proceedings of the third C1 esterase inhibitor deficiency workshop and beyond
    Angelo Agostoni
    University of Milan, Italy
    J Allergy Clin Immunol 114:S51-131. 2004
    ..This supplement seeks to raise awareness and aid diagnosis of HAE, optimize treatment for all patients, and provide a platform for further research in this rare, partially understood disorder...
  26. ncbi request reprint [Unexplained circulatory collapse after a motorcycle accident]
    Jonne Kalstad
    Anestesi og Intensivavdelingen, Nordlandssykehuset, 8092 Bodø
    Tidsskr Nor Laegeforen 124:1523-4. 2004
    ..Cardiac valve injury caused by non-penetrating chest trauma is unusual but may occur even after moderate injuries...
  27. ncbi request reprint [Acute intermittent porphyria]
    Geir Tollåli
    Medisinsk avdeling Nordland Sentralsykehus 8092 Bodø
    Tidsskr Nor Laegeforen 122:1102-5. 2002
    ..Acute intermittent porphyria is an autosomal dominant disease caused by a mutation in the gene coding for the porphobilinogen deaminase enzyme in the haem biosynthesis. The prevalence varies geographically...