Ludvig A Munthe

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi request reprint MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell receptor ligation facilitates switch to IgG production
    Ludvig A Munthe
    Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, N 0027 Oslo, Norway
    J Immunol 172:7476-84. 2004
  2. doi request reprint The cellular mechanism by which complementary Id+ and anti-Id antibodies communicate: T cells integrated into idiotypic regulation
    Johanne T Jacobsen
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Rikshospitalet, Oslo University Hospital Norway, Oslo, Norway
    Immunol Cell Biol 88:515-22. 2010
  3. pmc Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems
    Michael Zangani
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Rikshospitalet Medical Centre, N0027 Oslo, Norway
    Am J Pathol 174:1358-67. 2009
  4. doi request reprint Naive idiotope-specific B and T cells collaborate efficiently in the absence of dendritic cells
    Johanne Jacobsen
    Centre for Immune Regulation, Oslo University Hospital, University of Oslo, N 0372 Oslo, Norway
    J Immunol 192:4174-83. 2014
  5. pmc Lymphomas can develop from B cells chronically helped by idiotype-specific T cells
    Michael M Zangani
    Institute of Immunology, University of Oslo and Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    J Exp Med 204:1181-91. 2007
  6. doi request reprint Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells
    Audun Os
    Centre for Immune Regulation, Department of Immunology, University of Oslo, Oslo University Hospital, Rikshospitalet, 0424 Oslo, Norway
    Cell Rep 4:566-77. 2013
  7. ncbi request reprint Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models
    Alexandre Corthay
    University of Oslo, Institute of Immunology, Rikshospitalet University Hospital, N 0027 Oslo, Norway
    Cancer Immunol Immunother 53:759-69. 2004
  8. doi request reprint Isoform-specific regulation of immune cell reactivity by the catalytic subunit of protein kinase A (PKA)
    Ane Funderud
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Norway
    Cell Signal 21:274-81. 2009
  9. pmc Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
    Pier Adelchi Ruffini
    Department of Immunology, Centre for Immune Regulation, University of Oslo, Oslo University Hospital, Rikshospitalet, NO 0424 Oslo, Norway
    J Transl Med 12:207. 2014
  10. doi request reprint NF-κB activity in perinatal brain during infectious and hypoxic-ischemic insults revealed by a reporter mouse
    Anders Kielland
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Norway
    Brain Pathol 22:499-510. 2012

Collaborators

Detail Information

Publications12

  1. ncbi request reprint MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell receptor ligation facilitates switch to IgG production
    Ludvig A Munthe
    Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, N 0027 Oslo, Norway
    J Immunol 172:7476-84. 2004
    ..Taken together, V region-driven T-B collaboration may explain induction of natural IgM Abs (absence of BCR ligation) and IgG autoantibodies (BCR ligation by autoantigen) and may be involved in the development of autoimmunity...
  2. doi request reprint The cellular mechanism by which complementary Id+ and anti-Id antibodies communicate: T cells integrated into idiotypic regulation
    Johanne T Jacobsen
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Rikshospitalet, Oslo University Hospital Norway, Oslo, Norway
    Immunol Cell Biol 88:515-22. 2010
    ..A model is suggested that integrates present and previous data on B-cell regulation by Id-specific T cells...
  3. pmc Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems
    Michael Zangani
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Rikshospitalet Medical Centre, N0027 Oslo, Norway
    Am J Pathol 174:1358-67. 2009
    ....
  4. doi request reprint Naive idiotope-specific B and T cells collaborate efficiently in the absence of dendritic cells
    Johanne Jacobsen
    Centre for Immune Regulation, Oslo University Hospital, University of Oslo, N 0372 Oslo, Norway
    J Immunol 192:4174-83. 2014
    ..The results underscore the potency of anti-Id B cells in MHC class II-restricted presentation of Id(+) Ig and suggest that Id-specific T cell-B cell collaboration is of physiological relevance. ..
  5. pmc Lymphomas can develop from B cells chronically helped by idiotype-specific T cells
    Michael M Zangani
    Institute of Immunology, University of Oslo and Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    J Exp Med 204:1181-91. 2007
    ..Eventually, B lymphomas grew independent of T cells. Thus, T cells do not only eliminate cancers as currently believed. In fact, Id-specific Th2 cells can induce B lymphomas...
  6. doi request reprint Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells
    Audun Os
    Centre for Immune Regulation, Department of Immunology, University of Oslo, Oslo University Hospital, Rikshospitalet, 0424 Oslo, Norway
    Cell Rep 4:566-77. 2013
    ..The results suggest that CLL is driven by ongoing immune responses related to Th cell-CLL cell interaction. We propose that Th cells support malignant B cells and that they could be targeted in the treatment of CLL...
  7. ncbi request reprint Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models
    Alexandre Corthay
    University of Oslo, Institute of Immunology, Rikshospitalet University Hospital, N 0027 Oslo, Norway
    Cancer Immunol Immunother 53:759-69. 2004
    ....
  8. doi request reprint Isoform-specific regulation of immune cell reactivity by the catalytic subunit of protein kinase A (PKA)
    Ane Funderud
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Norway
    Cell Signal 21:274-81. 2009
    ..Our results imply that Calpha is required for normal immune cell reactivity and demonstrates isoform-specific effects and non-redundant functions of C subunit isoforms expressed in the same cell...
  9. pmc Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
    Pier Adelchi Ruffini
    Department of Immunology, Centre for Immune Regulation, University of Oslo, Oslo University Hospital, Rikshospitalet, NO 0424 Oslo, Norway
    J Transl Med 12:207. 2014
    ..We have here investigated whether such vaccines might elicit cross-reactive immune responses thus offering the possibility to immunize subsets of patients with the same vaccine...
  10. doi request reprint NF-κB activity in perinatal brain during infectious and hypoxic-ischemic insults revealed by a reporter mouse
    Anders Kielland
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Norway
    Brain Pathol 22:499-510. 2012
    ..In conclusion, by using this transgenic reporter mouse in experimental models of perinatal complications, we could assess NF-κB activity in vivo and subsequently determine the cellular origin in the tissues...
  11. doi request reprint B-cells and their targeting in rheumatoid arthritis--current concepts and future perspectives
    Britt Nakken
    Institute of Immunology, Rikshospitalet, Oslo University Hospital, Sognsvannsveien 20, Oslo, Norway
    Autoimmun Rev 11:28-34. 2011
    ..Better insights into the pathogenic role of B-cells provide efficacious opportunities to improve both therapy and prognosis of patients with RA...
  12. ncbi request reprint Therapeutic effect of idiotype-specific CD4+ T cells against B-cell lymphoma in the absence of anti-idiotypic antibodies
    Katrin U Lundin
    Institute of Immunology, University of Oslo, Rikshospitalet University Hospital, Oslo, Norway
    Blood 102:605-12. 2003
    ..The results show that Id-specific CD4+ T cells, in the absence of antibodies home to subcutaneous Id+ B lymphoma, become activated, induce inflammation, and prevent tumor development...