K Kristoffer Andersson

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi request reprint The use of high field/frequency EPR in studies of radical and metal sites in proteins and small inorganic models
    K Kristoffer Andersson
    Department of Biochemistry, University of Oslo, Blindern, Norway
    Spectrochim Acta A Mol Biomol Spectrosc 58:1101-12. 2002
  2. ncbi request reprint Examples of high-frequency EPR studies in bioinorganic chemistry
    K Kristoffer Andersson
    Department of Biochemistry, University of Oslo, Blindern, PO Box 1041, 0316, Oslo, Norway
    J Biol Inorg Chem 8:235-47. 2003
  3. pmc Spectroscopic studies of the iron and manganese reconstituted tyrosyl radical in Bacillus cereus ribonucleotide reductase R2 protein
    Ane B Tomter
    Department of Molecular Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 7:e33436. 2012
  4. pmc Review: studies of ferric heme proteins with highly anisotropic/highly axial low spin (S = 1/2) electron paramagnetic resonance signals with bis-histidine and histidine-methionine axial iron coordination
    Giorgio Zoppellaro
    Department of Molecular Biosciences, University of Oslo, PO Box 1041 Blindern, Oslo NO 0316, Norway
    Biopolymers 91:1064-82. 2009
  5. ncbi request reprint Crystallographic and spectroscopic studies of peroxide-derived myoglobin compound II and occurrence of protonated FeIV O
    Hans Petter Hersleth
    Department of Chemistry, University of Oslo, PO Box 1033, Blindern, Oslo N 0315, Norway
    J Biol Chem 282:23372-86. 2007
  6. pmc Cytochrome c-554 from Methylosinus trichosporium OB3b; a protein that belongs to the cytochrome c2 family and exhibits a HALS-Type EPR signal
    Espen Harbitz
    Department of Molecular Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 6:e22014. 2011
  7. ncbi request reprint Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse
    Kari R Strand
    Department of Molecular Biosciences, University of Oslo, PO Box 1041 Blindern, Oslo NO 0316, Norway
    J Biol Chem 279:46794-801. 2004
  8. pmc Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate
    Guro K Sandvik
    Department of Molecular Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 7:e42784. 2012
  9. pmc Modulation of the ligand-field anisotropy in a series of ferric low-spin cytochrome c mutants derived from Pseudomonas aeruginosa cytochrome c-551 and Nitrosomonas europaea cytochrome c-552: a nuclear magnetic resonance and electron paramagnetic resonance
    Giorgio Zoppellaro
    Department of Molecular Biosciences, University of Oslo, Post Office Box 1041 Blindern, Oslo NO 0316, Norway
    J Am Chem Soc 130:15348-60. 2008
  10. doi request reprint The crystal structure of peroxymyoglobin generated through cryoradiolytic reduction of myoglobin compound III during data collection
    Hans Petter Hersleth
    University of Oslo, Department of Molecular Biosciences, P O Box 1041 Blindern, N 0316 Oslo, Norway
    Biochem J 412:257-64. 2008

Collaborators

Detail Information

Publications35

  1. ncbi request reprint The use of high field/frequency EPR in studies of radical and metal sites in proteins and small inorganic models
    K Kristoffer Andersson
    Department of Biochemistry, University of Oslo, Blindern, Norway
    Spectrochim Acta A Mol Biomol Spectrosc 58:1101-12. 2002
    ..In Mn(II) substituted mouse RNR R2 protein the weakly interacting Mn(II) at X-band could be observed as decoupled Mn(II) at 285 GHz...
  2. ncbi request reprint Examples of high-frequency EPR studies in bioinorganic chemistry
    K Kristoffer Andersson
    Department of Biochemistry, University of Oslo, Blindern, PO Box 1041, 0316, Oslo, Norway
    J Biol Inorg Chem 8:235-47. 2003
    ..5 cm(-1), E=0.1 cm(-1), and g(x)= g(y)= g(z)=2.0. Finally, the effects of HF-EPR on X-band EPR silent states and weak magnetic interactions are demonstrated...
  3. pmc Spectroscopic studies of the iron and manganese reconstituted tyrosyl radical in Bacillus cereus ribonucleotide reductase R2 protein
    Ane B Tomter
    Department of Molecular Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 7:e33436. 2012
    ..2011) J Biol Chem 286: 33053-33060) indicates that both the manganese and iron reconstituted RNR R2F could be functional. The manganese form might be very important, as it has 8 times higher activity...
  4. pmc Review: studies of ferric heme proteins with highly anisotropic/highly axial low spin (S = 1/2) electron paramagnetic resonance signals with bis-histidine and histidine-methionine axial iron coordination
    Giorgio Zoppellaro
    Department of Molecular Biosciences, University of Oslo, PO Box 1041 Blindern, Oslo NO 0316, Norway
    Biopolymers 91:1064-82. 2009
    ..Nonetheless, a new linear correlation links the average shift delta of the heme methyl groups with the g(max) values...
  5. ncbi request reprint Crystallographic and spectroscopic studies of peroxide-derived myoglobin compound II and occurrence of protonated FeIV O
    Hans Petter Hersleth
    Department of Chemistry, University of Oslo, PO Box 1033, Blindern, Oslo N 0315, Norway
    J Biol Chem 282:23372-86. 2007
    ....
  6. pmc Cytochrome c-554 from Methylosinus trichosporium OB3b; a protein that belongs to the cytochrome c2 family and exhibits a HALS-Type EPR signal
    Espen Harbitz
    Department of Molecular Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 6:e22014. 2011
    ..The ligand field parameters observed for cytochrome c-554 fits the observed pattern for other cytochromes with similar ligation and EPR behaviour...
  7. ncbi request reprint Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse
    Kari R Strand
    Department of Molecular Biosciences, University of Oslo, PO Box 1041 Blindern, Oslo NO 0316, Norway
    J Biol Chem 279:46794-801. 2004
    ..Together, this might contribute to the lower affinity and cooperative binding of iron in mouse R2...
  8. pmc Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate
    Guro K Sandvik
    Department of Molecular Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 7:e42784. 2012
    ..A long half-life of the tyrosyl radical during wintertime anoxia could allow for continued cell division in crucian carp...
  9. pmc Modulation of the ligand-field anisotropy in a series of ferric low-spin cytochrome c mutants derived from Pseudomonas aeruginosa cytochrome c-551 and Nitrosomonas europaea cytochrome c-552: a nuclear magnetic resonance and electron paramagnetic resonance
    Giorgio Zoppellaro
    Department of Molecular Biosciences, University of Oslo, Post Office Box 1041 Blindern, Oslo NO 0316, Norway
    J Am Chem Soc 130:15348-60. 2008
    ..Thus, for these His-Met axially coordinated Fe(III), the large g(max) value EPR signal does not represent a special case as is observed for bis-His axially coordinated Fe(III) with the two His planes perpendicular to each other...
  10. doi request reprint The crystal structure of peroxymyoglobin generated through cryoradiolytic reduction of myoglobin compound III during data collection
    Hans Petter Hersleth
    University of Oslo, Department of Molecular Biosciences, P O Box 1041 Blindern, N 0316 Oslo, Norway
    Biochem J 412:257-64. 2008
    ..Additionally, we have observed that the Xe1 site is occupied by a water molecule, which might be the leaving group in the compound II to compound III reaction...
  11. ncbi request reprint Low-temperature EPR and Mössbauer spectroscopy of two cytochromes with His-Met axial coordination exhibiting HALS signals
    Giorgio Zoppellaro
    Department of Molecular Biosciences, University of Oslo, Box 1041 Blindern, 0316 Oslo, Norway
    Chemphyschem 7:1258-67. 2006
    ..Both EPR and Mössbauer data of axial cytochromes c with His-Met iron coordination are consistent with an electronic (d(xy))(2) (d(xz))(2) (d(yz))(1) ground state, which is typical for Type I model hemes...
  12. pmc Tuning of thioredoxin redox properties by intramolecular hydrogen bonds
    Asmund Kjendseth Røhr
    Department of Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 8:e69411. 2013
    ..We suggest that our model applies to other thioredoxin subclasses with similar active site arrangements. ..
  13. pmc HF-EPR, Raman, UV/VIS light spectroscopic, and DFT studies of the ribonucleotide reductase R2 tyrosyl radical from Epstein-Barr virus
    Ane B Tomter
    Department of Molecular Biosciences, University of Oslo, Oslo, Norway
    PLoS ONE 6:e25022. 2011
    ..Comparison with previous studies of RNR R2s from mouse, bacteria, and herpes viruses, demonstrates that finely tuned electronic properties of the radical exist within the same RNR R2 Ia class...
  14. ncbi request reprint Structures of the high-valent metal-ion haem-oxygen intermediates in peroxidases, oxygenases and catalases
    Hans Petter Hersleth
    Department of Chemistry, University of Oslo, P O Box 1033 Blindern, N 0315 Oslo, Norway
    J Inorg Biochem 100:460-76. 2006
    ..86-1.92A) in agreement with a single-bond character where the oxygen-atom is protonated...
  15. doi request reprint Circular dichroism and magnetic circular dichroism studies of the biferrous site of the class Ib ribonucleotide reductase from Bacillus cereus: comparison to the class Ia enzymes
    Ane B Tomter
    Department of Molecular Biosciences, University of Oslo, PO Box 1041 Blindern, 0316 Oslo, Norway
    Biochemistry 47:11300-9. 2008
    ..These structural differences have potential for the development of selective drugs...
  16. ncbi request reprint Structure, function, and mechanism of ribonucleotide reductases
    Matthias Kolberg
    Department of Molecular Biosciences, University of Oslo, P O Box 1041, Blindern, NO 0316 Oslo, Norway
    Biochim Biophys Acta 1699:1-34. 2004
    ....
  17. ncbi request reprint Circular dichroism and magnetic circular dichroism studies of the biferrous form of the R2 subunit of ribonucleotide reductase from mouse: comparison to the R2 from Escherichia coli and other binuclear ferrous enzymes
    Kari R Strand
    Department of Biochemistry, University of Oslo, NO 0316 Oslo, Norway
    Biochemistry 42:12223-34. 2003
    ..These results are compared with those from reduced Escherichia coli R2 and reduced acyl-carrier protein Delta(9) desaturase to correlate to similarities and differences in their dioxygen reactivity...
  18. doi request reprint How different oxidation states of crystalline myoglobin are influenced by X-rays
    Hans Petter Hersleth
    Department of Molecular Biosciences, University of Oslo, P O Box 1041 Blindern, NO 0316 Oslo, Norway
    Biochim Biophys Acta 1814:785-96. 2011
    ..This article is part of a Special Issue entitled: Protein Structure and Function in the Crystalline State...
  19. doi request reprint The class Ib ribonucleotide reductase from Mycobacterium tuberculosis has two active R2F subunits
    Marta Hammerstad
    Department of Biosciences, Section of Biochemistry and Molecular Biology, University of Oslo, PO Box 1066, Blindern, 0316, Oslo, Norway
    J Biol Inorg Chem 19:893-902. 2014
    ..We also report enzymatic activity of Fe 2 (III) -R2F-1 when assayed with R1, and suggest that the active M. tuberculosis class Ib RNR can use two different small subunits, R2F-1 and R2F-2, with similar activity...
  20. doi request reprint Crystal structure of Bacillus cereus class Ib ribonucleotide reductase di-iron NrdF in complex with NrdI
    Marta Hammerstad
    Department of Biosciences, University of Oslo, P O Box 1066, Blindern, NO 0316 Oslo, Norway
    ACS Chem Biol 9:526-37. 2014
    ..The mode of interactions between the proteins involved in the class Ib RNR system is, however, not fully resolved. ..
  21. pmc Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4
    Linn G Bjørnstad
    Department of Molecular Biosciences, University of Oslo, Blindern, NO 0316 Oslo, Norway
    Biochem J 434:391-8. 2011
    ..The present results demonstrate that ALKBH4 represents an active Fe(II)/2OG-dependent decarboxylase and suggest that the cysteine cluster is involved in processes other than Fe co-ordination...
  22. pmc Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of a ferredoxin/flavodoxin-NADP(H) oxidoreductase (Bc0385) from Bacillus cereus
    Silje Skråmo
    Department of Biosciences, Section for Biochemistry and Molecular Biology, University of Oslo, PO Box 1066, Blindern, NO 0316 Oslo, Norway
    Acta Crystallogr F Struct Biol Commun 70:777-80. 2014
    ..2, b=164.3, c=95.0 Å, containing two FNR molecules in the asymmetric unit. The structure of the Bc0385 FNR has been solved by molecular replacement, and is a member of the homodimeric thioredoxin reductase-like class of FNRs...
  23. ncbi request reprint Cobalt substitution of mouse R2 ribonucleotide reductase as a model for the reactive diferrous state: spectroscopic and structural evidence for a ferromagnetically coupled dinuclear cobalt cluster
    Kari R Strand
    Department of Biochemistry, University of Oslo, P O Box 1041, Blindern, Oslo N 0316, Norway
    J Biol Chem 277:34229-38. 2002
    ..This might be important for proper O(2) activation of the more exposed native diferrous site in mouse R2 compared with E. coli R2...
  24. pmc A continuous-wave electron-nuclear double resonance (X-band) study of the Cu2+ sites of particulate methane mono-oxygenase of Methylococcus capsulatus (strain M) in membrane and pure dopamine beta-mono-oxygenase of the adrenal medulla
    Bettina Katterle
    Department of Biochemistry, University of Oslo, P O Box 1041 Blindern, N 0316 Oslo, Norway
    Biochem J 363:677-86. 2002
    ..In conclusion, the resting EPR visible Cu in pMMO is not part of a trinuclear cluster, as has been suggested previously...
  25. doi request reprint Cyclic diguanylate regulation of Bacillus cereus group biofilm formation
    Annette Fagerlund
    Laboratory for Microbial Dynamics LaMDa, Section for Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, PB1068, Oslo, 0316, Norway
    Mol Microbiol 101:471-94. 2016
    ..Only two cdg genes (cdgA, cdgJ) had orthologs in B. subtilis, highlighting differences in c-di-GMP signalling between B. subtilis and B. cereus group bacteria. ..
  26. ncbi request reprint Circular dichroism and magnetic circular dichroism studies of the active site of p53R2 from human and mouse: iron binding and nature of the biferrous site relative to other ribonucleotide reductases
    Pin Pin Wei
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    Biochemistry 45:14043-51. 2006
    ..The difference in ferrous affinity between mammalian R2 and p53R2 suggests the possibility of specific inhibition of DNA precursor synthesis during cell division...
  27. pmc The membrane-associated form of methane mono-oxygenase from Methylococcus capsulatus (Bath) is a copper/iron protein
    Piku Basu
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, U K
    Biochem J 369:417-27. 2003
    ..The EPR measurements also demonstrated the presence of a tightly bound mononuclear Fe(3+) ion in an octahedral environment that may well be exchange-coupled to another paramagnetic species...
  28. ncbi request reprint Spectroscopic and electronic structure studies of the trinuclear Cu cluster active site of the multicopper oxidase laccase: nature of its coordination unsaturation
    Liliana Quintanar
    Department of Chemistry, Stanford University, Stanford, California 94305 5080, USA
    J Am Chem Soc 127:13832-45. 2005
    ..These tune the ligand binding properties of the cluster, leading to its high affinity for fluoride and its coordination unsaturation in aqueous media, which play a key role in its O2 reactivity...
  29. ncbi request reprint Evidence of two distinct oxygen complexes of reduced endothelial nitric oxide synthase
    Stephane Marchal
    INSERM U431, Département Biologie Santé, Universite Montpellier II, IFR 122, Place Eugene Bataillon, 34095 Montpellier Cedex 5, France
    J Biol Chem 279:19824-31. 2004
    ..Heme-oxy II, which is the oxygen complex competent for product formation, appears to represent a distinct conformation in which the electronic configuration is essentially locked in the ferric superoxide complex...
  30. ncbi request reprint The use of multi-frequency EPR techniques to identify the radicals produced in irradiated beta-blockers
    Alix Engalytcheff
    Laboratory of Chemical and Physicochemical Analysis of Drugs CHAM, UCL, Avenue Mounier, 72 30, B 1200 Bruxelles, Belgium
    Free Radic Res 38:59-66. 2004
    ..These two conclusions drawn from the EPR results on beta-blockers show clearly the importance of continuing the investigations on radiolytic mechanisms in solid-state drugs...
  31. pmc The protonation status of compound II in myoglobin, studied by a combination of experimental data and quantum chemical calculations: quantum refinement
    Kristina Nilsson
    Department of Theoretical Chemistry, Lund University, Lund, Sweden
    Biophys J 87:3437-47. 2004
    ..Combined with the available spectroscopic data, this indicates that compound II in myoglobin is protonated and is best described as FeIV OH-. It accepts a hydrogen bond from the distal His, which may be protonated at low pH...
  32. ncbi request reprint The active site residue tyrosine 325 influences iron binding and coupling efficiency in human phenylalanine hydroxylase
    Frederico F Miranda
    Department of Biomedicine, University of Bergen, Jonas Lies vei 91, NO 5009 Bergen, Norway
    J Inorg Biochem 99:1320-8. 2005
    ..In addition, the residue appears to be important for the correct cooperative regulation by l-Phe...
  33. ncbi request reprint Tetrahydrobiopterin as combined electron/proton donor in nitric oxide biosynthesis: cryogenic UV-Vis and EPR detection of reaction intermediates
    Antonius C F Gorren
    Department of Pharmacology and Toxicology, Karl Franzens University Graz, Austria
    Methods Enzymol 396:456-66. 2005
    ..In this chapter, the suitability, drawbacks, and advantages of cryogenic methods are discussed...
  34. ncbi request reprint One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime
    Ole Terland
    Department of Biomedicine, Section for Biochemistry and Molecular Biology, University of Bergen, Jonas Lies vei 91, N 5009 Bergen, Norway
    Free Radic Biol Med 41:1266-71. 2006
    ....
  35. doi request reprint Thermodynamic analysis of L-arginine and N omega-hydroxy-L-arginine binding to nitric oxide synthase
    Henrik Zakariassen
    Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, P O Box 5003, N 1432 Aas, Norway
    Biochim Biophys Acta 1784:806-10. 2008
    ..The changes in heat capacity (DeltaC(p)) are relatively small for binding of both NHA and L-Arg (-53+/-18 and -95+/-23 cal/L mol, respectively), which indicates that hydrophobic interactions contribute little to binding...