Cathrine Thomsen

Summary

Affiliation: Norwegian Institute of Public Health
Country: Norway

Publications

  1. pmc Association between perfluoroalkyl substances and thyroid stimulating hormone among pregnant women: a cross-sectional study
    Yan Wang
    Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA
    Environ Health 12:76. 2013
  2. doi request reprint Changes in concentrations of perfluorinated compounds, polybrominated diphenyl ethers, and polychlorinated biphenyls in Norwegian breast-milk during twelve months of lactation
    Cathrine Thomsen
    Department of Analytical Chemistry, Division of Environmental Medicine, Norwegian Institute of Public Health, PO Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Sci Technol 44:9550-6. 2010
  3. doi request reprint Determinants of brominated flame retardants in breast milk from a large scale Norwegian study
    Cathrine Thomsen
    Department of Analytical Chemistry, Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Int 36:68-74. 2010
  4. ncbi request reprint Automated solid-phase extraction for the determination of polybrominated diphenyl ethers and polychlorinated biphenyls in serum--application on archived Norwegian samples from 1977 to 2003
    Cathrine Thomsen
    Norwegian Institute of Public Health, P O Box 4404, Nydalen, N 0403 Oslo, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 846:252-63. 2007
  5. doi request reprint Consumption of fish from a contaminated lake strongly affects the concentrations of polybrominated diphenyl ethers and hexabromocyclododecane in serum
    Cathrine Thomsen
    Norwegian Institute of Public Health, Oslo, Norway
    Mol Nutr Food Res 52:228-37. 2008
  6. doi request reprint Sex, BMI and age in addition to dietary intakes influence blood concentrations and congener profiles of dioxins and PCBs
    Helle K Knutsen
    Norwegian Institute of Public Health, Oslo, Norway
    Mol Nutr Food Res 55:772-82. 2011
  7. doi request reprint Dietary exposure to brominated flame retardants correlates with male blood levels in a selected group of Norwegians with a wide range of seafood consumption
    Helle K Knutsen
    Norwegian Institute of Public Health, Oslo, Norway
    Mol Nutr Food Res 52:217-27. 2008
  8. doi request reprint Diet and particularly seafood are major sources of perfluorinated compounds in humans
    Line S Haug
    Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Int 36:772-8. 2010
  9. doi request reprint Development and validation of prediction models for blood concentrations of dioxins and PCBs using dietary intakes
    Helen Engelstad Kvalem
    Norwegian Institute of Public Health, Oslo, Norway
    Environ Int 50:15-21. 2012
  10. doi request reprint Placental transfer of perfluorinated compounds is selective--a Norwegian Mother and Child sub-cohort study
    Kristine Bjerve Gutzkow
    Norwegian Institute of Public Health, Division of Environmental Medicine, Department of Chemical Toxicology, PO Box 4404 Nydalen, NO 0403 Oslo, Norway
    Int J Hyg Environ Health 215:216-9. 2012

Collaborators

Detail Information

Publications38

  1. pmc Association between perfluoroalkyl substances and thyroid stimulating hormone among pregnant women: a cross-sectional study
    Yan Wang
    Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA
    Environ Health 12:76. 2013
    ..The objective of this study was to examine the association between plasma concentrations of PFASs and thyroid stimulating hormone (TSH) among pregnant women...
  2. doi request reprint Changes in concentrations of perfluorinated compounds, polybrominated diphenyl ethers, and polychlorinated biphenyls in Norwegian breast-milk during twelve months of lactation
    Cathrine Thomsen
    Department of Analytical Chemistry, Division of Environmental Medicine, Norwegian Institute of Public Health, PO Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Sci Technol 44:9550-6. 2010
    ..There were no significant differences in isomer pattern between the mothers, or changes during the lactation period. After a year of nursing the breast-milk concentrations of PFCs, PBDEs, and PCBs were reduced by 15-94%...
  3. doi request reprint Determinants of brominated flame retardants in breast milk from a large scale Norwegian study
    Cathrine Thomsen
    Department of Analytical Chemistry, Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Int 36:68-74. 2010
    ..Our results show that sources other than the diet are important for the variability seen in breast milk BFR concentrations and that exposure from the indoor atmosphere should be emphasized in future studies...
  4. ncbi request reprint Automated solid-phase extraction for the determination of polybrominated diphenyl ethers and polychlorinated biphenyls in serum--application on archived Norwegian samples from 1977 to 2003
    Cathrine Thomsen
    Norwegian Institute of Public Health, P O Box 4404, Nydalen, N 0403 Oslo, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 846:252-63. 2007
    ....
  5. doi request reprint Consumption of fish from a contaminated lake strongly affects the concentrations of polybrominated diphenyl ethers and hexabromocyclododecane in serum
    Cathrine Thomsen
    Norwegian Institute of Public Health, Oslo, Norway
    Mol Nutr Food Res 52:228-37. 2008
    ..The median serum HBCD concentration was 4.1 and 2.6 ng/g lipids for men and women, respectively, and was also found to be associated with consumption of fish from Lake Mjøsa...
  6. doi request reprint Sex, BMI and age in addition to dietary intakes influence blood concentrations and congener profiles of dioxins and PCBs
    Helle K Knutsen
    Norwegian Institute of Public Health, Oslo, Norway
    Mol Nutr Food Res 55:772-82. 2011
    ....
  7. doi request reprint Dietary exposure to brominated flame retardants correlates with male blood levels in a selected group of Norwegians with a wide range of seafood consumption
    Helle K Knutsen
    Norwegian Institute of Public Health, Oslo, Norway
    Mol Nutr Food Res 52:217-27. 2008
    ..Further, significant but weak correlations were found between dietary exposure and serum levels for Sum PBDEs, BDE-47, and BDE-28 in males. This indicates that other sources in addition to diet need to be addressed...
  8. doi request reprint Diet and particularly seafood are major sources of perfluorinated compounds in humans
    Line S Haug
    Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Int 36:772-8. 2010
    ..Further, significant relationships between estimated dietary intakes and serum concentrations have been demonstrated for the first time...
  9. doi request reprint Development and validation of prediction models for blood concentrations of dioxins and PCBs using dietary intakes
    Helen Engelstad Kvalem
    Norwegian Institute of Public Health, Oslo, Norway
    Environ Int 50:15-21. 2012
    ..In large epidemiologic studies, exposure estimates of these compounds based on analyses of biological material might not be available or affordable...
  10. doi request reprint Placental transfer of perfluorinated compounds is selective--a Norwegian Mother and Child sub-cohort study
    Kristine Bjerve Gutzkow
    Norwegian Institute of Public Health, Division of Environmental Medicine, Department of Chemical Toxicology, PO Box 4404 Nydalen, NO 0403 Oslo, Norway
    Int J Hyg Environ Health 215:216-9. 2012
    ..Additionally, the sulfonate group seems to impede transfer efficiency. This indicates a selective placental passage of the different PFCs and hence a specific foetal exposure...
  11. doi request reprint Role of dietary patterns for dioxin and PCB exposure
    Helen E Kvalem
    Norwegian Institute of Public Health, Oslo, Norway
    Mol Nutr Food Res 53:1438-51. 2009
    ..Two were related to high intakes, one dominated by oily fish ((Omega-3)), the other by fish liver and seagull eggs ("northern coastal"). Only the latter was closely associated with high blood concentrations of dioxins and PCBs...
  12. ncbi request reprint Comparing electron ionization high-resolution and electron capture low-resolution mass spectrometric determination of polybrominated diphenyl ethers in plasma, serum and milk
    Cathrine Thomsen
    National Institute of Public Health, Oslo, Norway
    Chemosphere 46:641-8. 2002
    ..The method repeatability including sample preparation was in the range 4.7-8.4% and 0.6-10% relative standard deviation (RSD) for the GC-LRMS (ECNI) and GC-HRMS (EI) systems, respectively...
  13. doi request reprint Levels in food and beverages and daily intake of perfluorinated compounds in Norway
    Line Småstuen Haug
    Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404, Nydalen, NO 0403 Oslo, Norway
    Chemosphere 80:1137-43. 2010
    ..This study illustrates that by improving the analytical methods for determination of PFC in food samples, a broad range of compounds can be detected, which is important when assessing dietary exposure...
  14. doi request reprint Characterisation of human exposure pathways to perfluorinated compounds--comparing exposure estimates with biomarkers of exposure
    Line S Haug
    Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Int 37:687-93. 2011
    ..Even though food in general is the major source of exposure for PFCs, the indoor environment may be an important contributor to human exposure. This study provides valuable knowledge for risk assessment of PFCs and control strategies...
  15. pmc Levels of hexachlorobenzene (HCB) in breast milk in relation to birth weight in a Norwegian cohort
    Merete Eggesbø
    Department of Genes and Environment, Division of Epidemiology, Norwegian Institute of Public Health, P O Box 4404, Nydalen, N 0403 Oslo, Norway
    Environ Res 109:559-66. 2009
    ..However, its potential for reproductive toxicity in humans exposed to background levels has not been fully evaluated. Here we examined the association between maternal levels of HCB and their infants' birth weight...
  16. doi request reprint A sensitive method for determination of a broad range of perfluorinated compounds in serum suitable for large-scale human biomonitoring
    Line Småstuen Haug
    Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404, Nydalen, NO 0403 Oslo, Norway
    J Chromatogr A 1216:385-93. 2009
    ..This column-switching technique can easily be set up on standard LC-MS/MS instruments and is thus available to a wide range of laboratories...
  17. doi request reprint Determinants of plasma PCB, brominated flame retardants, and organochlorine pesticides in pregnant women and 3 year old children in The Norwegian Mother and Child Cohort Study
    Ida Henriette Caspersen
    Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway Electronic address
    Environ Res 146:136-44. 2016
    ..Exposure to persistent organic pollutants (POPs) during prenatal and postnatal life has been extensively studied in relation to adverse health effects in children...
  18. doi request reprint Investigation on per- and polyfluorinated compounds in paired samples of house dust and indoor air from Norwegian homes
    Line S Haug
    Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Sci Technol 45:7991-8. 2011
    ..These results are important for estimating the exposure to PFCs from the indoor environment and for characterization of exposure pathways...
  19. ncbi request reprint Comparison of GC and LC determinations of hexabromocyclododecane in biological samples - results from two interlaboratory comparison studies
    Line S Haug
    Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404 Nydalen, N 0403 Oslo, Norway
    Chemosphere 71:1087-92. 2008
    ..To our knowledge, this is the first report on interlaboratory comparison studies concerning the determination of HBCD in biological samples comprising results from a sufficient number of participants to perform a statistical evaluation...
  20. pmc Associations between brominated flame retardants in human milk and thyroid-stimulating hormone (TSH) in neonates
    Merete Eggesbø
    Department of Genes and Environment, Division of Epidemiology, Norwegian Institute of Public Health, PO Box 4404 Nydalen, N 0403 Oslo, Norway
    Environ Res 111:737-43. 2011
    ..However, few reports on newborns have been published to date...
  21. doi request reprint Pre-natal exposure to perfluoroalkyl substances may be associated with altered vaccine antibody levels and immune-related health outcomes in early childhood
    Berit Granum
    Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway
    J Immunotoxicol 10:373-9. 2013
    ..The results indicate that pre-natal exposure to PFAS may be associated with immunosuppression in early childhood...
  22. ncbi request reprint A new method for determination of halogenated flame retardants in human milk using solid-phase extraction
    Cathrine Thomsen
    National Institute of Public Health, Oslo, Norway
    J Anal Toxicol 26:129-37. 2002
    ..Estimated limits of detection were in the range of 0.3 to 1.0 pg/g milk using a sample size of 5 g for all compounds, except TCBP-A, for which the limit of detection was estimated to 6.7 pg/g milk...
  23. ncbi request reprint Brominated flame retardants in archived serum samples from Norway: a study on temporal trends and the role of age
    Cathrine Thomsen
    National Institute of Public Health, Oslo, Norway
    Environ Sci Technol 36:1414-8. 2002
    ..The present study indicates an ongoing increase in human exposure to BFRs, and the current body burden appears to be independent of age, except for infants (0-4 years old), who seem to experience elevated exposure...
  24. ncbi request reprint Occupational exposure to hexabromocyclododecane at an industrial plant
    Cathrine Thomsen
    Norwegian Institute of Public Health, P O Box 4404 Nydalen, N 0403 Oslo, Norway
    Environ Sci Technol 41:5210-6. 2007
    ..The elevated exposure levels reported in this study compared to urban air and serum levels in general populations suggest that further and more detailed exposure assessment studies should be initiated in industries where HBCD is applied...
  25. doi request reprint Novel application of statistical methods for analysis of multiple toxicants identifies DDT as a risk factor for early child behavioral problems
    Joan Forns
    Department of Genes and Environment, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Environ Res 151:91-100. 2016
    ....
  26. doi request reprint Perinatal exposure to dioxins and dioxin-like compounds and infant growth and body mass index at seven years: A pooled analysis of three European birth cohorts
    Nina Iszatt
    Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Environ Int 94:399-407. 2016
    ..However, the few epidemiological investigations on dioxins are inconclusive. We investigated perinatal exposure to dioxins and dioxin-like compounds, infant growth and body mass index (BMI) in childhood...
  27. doi request reprint Development of an ion-pair liquid chromatography-high resolution mass spectrometry method for determination of organophosphate pesticide metabolites in large-scale biomonitoring studies
    Enrique Cequier
    Department of Exposure and Risk Assessment, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway Electronic address
    J Chromatogr A 1454:32-41. 2016
    ..The method was proven robust and suitable for large-scale biomonitoring studies. ..
  28. doi request reprint Determination of 12 urinary phthalate metabolites in Norwegian pregnant women by core-shell high performance liquid chromatography with on-line solid-phase extraction, column switching and tandem mass spectrometry
    Azemira Sabaredzovic
    Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway Electronic address
    J Chromatogr B Analyt Technol Biomed Life Sci 1002:343-52. 2015
    ..The urinary concentrations for most of the phthalate metabolites in the present study were found to be in the same range as found in other studies of pregnant women. ..
  29. doi request reprint Human exposure pathways to organophosphate triesters - a biomonitoring study of mother-child pairs
    Enrique Cequier
    Department of Exposure and Risk Assessment, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Marcel li Domingo s n, 43007 Tarragona, Spain Electronic address
    Environ Int 75:159-65. 2015
    ..This suggests that the residential environment is a more important exposure pathway to PFRs than the diet. ..
  30. doi request reprint Comparing human exposure to emerging and legacy flame retardants from the indoor environment and diet with concentrations measured in serum
    Enrique Cequier
    Department of Exposure and Risk Assessment, Norwegian Institute of Public Health, Oslo, Norway Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Tarragona, Spain Electronic address
    Environ Int 74:54-9. 2015
    ....
  31. doi request reprint A high-throughput method for determination of metabolites of organophosphate flame retardants in urine by ultra performance liquid chromatography-high resolution mass spectrometry
    Enrique Cequier
    Department of Exposure and Risk Assessment, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway Departament of Analytical Chemistry and Organic Chemistry, University of Rovira i Virgili, Carrer Marcel li Domingo s n, 43007 Tarragona, Spain Electronic address
    Anal Chim Acta 845:98-104. 2014
    ..BDCIPP was however, detected above the method limit of detection (MLD) with GM of 0.13 ng mL(-1) and 0.20 ng mL(-1). While occasionally detected, the GM of DNBP and BBOEP were below MLD in both groups...
  32. doi request reprint Occurrence of a broad range of legacy and emerging flame retardants in indoor environments in Norway
    Enrique Cequier
    Department of Exposure and Risk Assessment, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway
    Environ Sci Technol 48:6827-35. 2014
    ..The main findings were that frequent vacuum cleaning resulted in lower FR concentrations in dust and that dermal contact with dust, for both children and mothers, was as important for the intake of organophosphate FRs as dust ingestion. ..
  33. doi request reprint Determination of emerging halogenated flame retardants and polybrominated diphenyl ethers in serum by gas chromatography mass spectrometry
    Enrique Cequier
    Department of Exposure and Risk Assessment, Norwegian Institute of Public Health, Oslo, Norway Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, Tarragona, Spain Electronic address
    J Chromatogr A 1310:126-32. 2013
    ..In human serum samples from Norway, we were able to detect and quantify hexabromobenzene, 1,2-bis[2,4,6-tribromophenoxy] ethane, Dechlorane Plus(®), Dechlorane 602 and 603...
  34. doi request reprint High throughput online solid phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry method for polyfluoroalkyl phosphate esters, perfluoroalkyl phosphonates, and other perfluoroalkyl substances in human serum, plasma, and w
    Somrutai Poothong
    Domain for Infection Control and Environmental Health, Norwegian Institute of Public Health, P O Box 4404, Nydalen, NO 0403, Oslo, Norway Department of Chemistry, University of Oslo, P O Box 1033, Blindern, NO 0315, Oslo, Norway Electronic address
    Anal Chim Acta 957:10-19. 2017
    ..The method was also successfully applied to samples of human plasma and whole blood with coefficients of variation in the range 0.8-15.2% (n = 5)...
  35. doi request reprint Concentrations of phthalates and bisphenol A in Norwegian foods and beverages and estimated dietary exposure in adults
    Amrit K Sakhi
    Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway Electronic address
    Environ Int 73:259-69. 2014
    ..The estimated dietary exposures to these chemicals were considerably lower than their respective tolerable daily intake (TDI) values established by the European Food Safety Authority (EFSA)...
  36. pmc Perfluorinated compounds and subfecundity in pregnant women
    Kristina W Whitworth
    Department of Health and Human Services, National Institute for Environmental Health Sciences, National Institutes of Health, Durham, NC 27709, USA
    Epidemiology 23:257-63. 2012
    ..We examined subfecundity in relation to 2 perfluorinated compounds-perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA)...
  37. ncbi request reprint Time trends and the influence of age and gender on serum concentrations of perfluorinated compounds in archived human samples
    Line S Haug
    Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Environ Sci Technol 43:2131-6. 2009
    ..For most PFCs, the concentrations in the human serum samples were found to increase with age in the pools from 2007, while the results for 1976, 1987, and 1998 were more varying. Several PFCs were significantly intercorrelated...
  38. ncbi request reprint Hexabromocyclododecane challenges scientists and regulators
    Robin J Law
    Centre for Environment, Fisheries and Aquaculture Science, United Kingdom
    Environ Sci Technol 39:281A-287A. 2005