Kelvin Kwok Chai Ng

Summary

Publications

  1. pmc Combined resection and radiofrequency ablation for multifocal hepatocellular carcinoma: prognosis and outcomes
    Tan To Cheung
    Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Queen Mary Hospital, Hong Kong, China
    World J Gastroenterol 16:3056-62. 2010
  2. ncbi request reprint Efficacy and safety of radiofrequency ablation for perivascular hepatocellular carcinoma without hepatic inflow occlusion
    K K Ng
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Br J Surg 93:440-7. 2006
  3. ncbi request reprint Thermal ablative therapy for malignant liver tumors: a critical appraisal
    Kelvin Kwok Chai Ng
    Departments of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    J Gastroenterol Hepatol 18:616-29. 2003
  4. ncbi request reprint Radiofrequency ablation as a salvage procedure for ruptured hepatocellular carcinoma
    K K Ng
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Hepatogastroenterology 50:1641-3. 2003
  5. ncbi request reprint Safety limit of large-volume hepatic radiofrequency ablation in a rat model
    Kelvin K Ng
    Centre for the Study of Liver Disease and Departments of Surgery and Pathology, University of Hong Kong, Pokfulam, Hong Kong
    Arch Surg 141:252-8. 2006
  6. ncbi request reprint Porcine liver: morphologic characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes
    Kelvin K Ng
    Departments of Surgery and Pathology and Centre for the Study of Liver Disease, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Radiology 235:478-86. 2005
  7. ncbi request reprint Delayed portal vein thrombosis after experimental radiofrequency ablation near the main portal vein
    K K C Ng
    Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, China
    Br J Surg 91:632-9. 2004
  8. ncbi request reprint Analysis of recurrence pattern and its influence on survival outcome after radiofrequency ablation of hepatocellular carcinoma
    Kelvin K Ng
    Department of Surgery, The University of Hong Kong Medical Center, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    J Gastrointest Surg 12:183-91. 2008
  9. doi request reprint Can positron emission tomography with the dual tracers [11 C]acetate and [18 F]fludeoxyglucose predict microvascular invasion in hepatocellular carcinoma?
    Tan To Cheung
    Department of Surgery, University of Hong Kong, Hong Kong, China
    Liver Transpl 17:1218-25. 2011
  10. ncbi request reprint Radiofrequency ablation for subcapsular hepatocellular carcinoma
    Ronnie Tung Ping Poon
    Centre for the Study of Liver Disease and the Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg Oncol 11:281-9. 2004

Collaborators

Detail Information

Publications41

  1. pmc Combined resection and radiofrequency ablation for multifocal hepatocellular carcinoma: prognosis and outcomes
    Tan To Cheung
    Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Queen Mary Hospital, Hong Kong, China
    World J Gastroenterol 16:3056-62. 2010
    ..To analyze the combined treatment of resection and intraoperative radiofrequency ablation (RFA) for multifocal hepatocellular carcinoma in terms of prognosis and surgical outcomes...
  2. ncbi request reprint Efficacy and safety of radiofrequency ablation for perivascular hepatocellular carcinoma without hepatic inflow occlusion
    K K Ng
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Br J Surg 93:440-7. 2006
    ..This study aimed to evaluate the safety and efficacy of RFA for perivascular HCC without hepatic inflow occlusion...
  3. ncbi request reprint Thermal ablative therapy for malignant liver tumors: a critical appraisal
    Kelvin Kwok Chai Ng
    Departments of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    J Gastroenterol Hepatol 18:616-29. 2003
    ..As each of the loco-regional therapies has its own advantages and limitations, a multidisciplinary approach using a combination of therapies will be the future trend for the management of malignant liver tumors...
  4. ncbi request reprint Radiofrequency ablation as a salvage procedure for ruptured hepatocellular carcinoma
    K K Ng
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Hepatogastroenterology 50:1641-3. 2003
    ..We report a case where radiofrequency ablation was used as a salvage procedure for ruptured hepatocellular carcinoma during emergency laparotomy...
  5. ncbi request reprint Safety limit of large-volume hepatic radiofrequency ablation in a rat model
    Kelvin K Ng
    Centre for the Study of Liver Disease and Departments of Surgery and Pathology, University of Hong Kong, Pokfulam, Hong Kong
    Arch Surg 141:252-8. 2006
    ..This study aimed to investigate the possible systemic responses of large-volume hepatic RFA and to estimate its safety limit in normal and cirrhotic rats...
  6. ncbi request reprint Porcine liver: morphologic characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes
    Kelvin K Ng
    Departments of Surgery and Pathology and Centre for the Study of Liver Disease, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Radiology 235:478-86. 2005
    ..To evaluate morphologic characteristics and cell viability of radiofrequency ablation zones in porcine liver...
  7. ncbi request reprint Delayed portal vein thrombosis after experimental radiofrequency ablation near the main portal vein
    K K C Ng
    Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, China
    Br J Surg 91:632-9. 2004
    ..This study aimed to investigate the local effect of RFA on the main portal vein branch, and the completeness of cellular ablation in its vicinity, with or without a Pringle manoeuvre using a porcine model...
  8. ncbi request reprint Analysis of recurrence pattern and its influence on survival outcome after radiofrequency ablation of hepatocellular carcinoma
    Kelvin K Ng
    Department of Surgery, The University of Hong Kong Medical Center, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    J Gastrointest Surg 12:183-91. 2008
    ..There is no data on the analysis of recurrence pattern and its influence on long-term survival outcome after RFA in HCC patients...
  9. doi request reprint Can positron emission tomography with the dual tracers [11 C]acetate and [18 F]fludeoxyglucose predict microvascular invasion in hepatocellular carcinoma?
    Tan To Cheung
    Department of Surgery, University of Hong Kong, Hong Kong, China
    Liver Transpl 17:1218-25. 2011
    ..Preoperative [(18) F]FDG PET may predict microvascular invasion. The addition of [(11) C]acetate improves the overall sensitivity of PET, but it has no incremental value in predicting microvascular invasion...
  10. ncbi request reprint Radiofrequency ablation for subcapsular hepatocellular carcinoma
    Ronnie Tung Ping Poon
    Centre for the Study of Liver Disease and the Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg Oncol 11:281-9. 2004
    ..Limited data from recent studies suggested an increased risk of bleeding complications, needle-track seeding, and local recurrence after radiofrequency ablation (RFA) of subcapsular hepatocellular carcinoma (HCC)...
  11. ncbi request reprint Portal vein thrombosis after radiofrequency ablation for recurrent hepatocellular carcinoma
    Kelvin Kwok Chai Ng
    Centre for the Study of Liver Disease, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong
    Asian J Surg 26:50-3; discussion 54. 2003
    ..We present a case of portal vein thrombosis as a complication of RFA treatment for recurrent HCC and illustrate its underlying possible mechanism...
  12. doi request reprint Safety and efficacy of radiofrequency ablation for periductal hepatocellular carcinoma with intraductal cooling of the central bile duct
    Vincent Wai To Lam
    Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    J Am Coll Surg 207:e1-5. 2008
  13. ncbi request reprint Impact of preoperative fine-needle aspiration cytologic examination on clinical outcome in patients with hepatocellular carcinoma in a tertiary referral center
    Kelvin Kwok Chai Ng
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong
    Arch Surg 139:193-200. 2004
    ..Preoperative fine-needle aspiration cytologic examination (FNAC) exerts a statistically significant adverse effect on long-term clinical outcome in patients with hepatocellular carcinoma (HCC)...
  14. pmc A case of laparoscopic hepatectomy for recurrent hepatocellular carcinoma
    Tan To Cheung
    Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Queen Mary Hospital, Hong Kong, China
    World J Gastroenterol 16:526-30. 2010
    ....
  15. doi request reprint Risk factors and prognostic factors of local recurrence after radiofrequency ablation of hepatocellular carcinoma
    Vincent Wai To Lam
    Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China Cancer Institute, New South Wales, Australia
    J Am Coll Surg 207:20-9. 2008
    ..Local recurrence rates after radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) vary from 2% to 36% in the literature. Limited data were available about the prognostic significance of local recurrence...
  16. doi request reprint Pediatric liver transplantation in Hong Kong-a domain with scarce deceased donors
    Kwong Leung Chan
    Department of Surgery, The University of Hong Kong, Hong Kong, China
    J Pediatr Surg 44:2316-21. 2009
    ..The study aimed to assess the outcome of live-donor liver transplantation for pediatric patients in a region with limited access to deceased donors...
  17. ncbi request reprint High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies
    Ronnie T P Poon
    Department of Surgery, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, China
    Ann Surg Oncol 14:1835-45. 2007
    ..This study investigated the prognostic significance of pre-treatment serum VEGF level in patients with HCC undergoing RFA treatment...
  18. doi request reprint Liver transplantation for hepatocellular carcinoma: the Hong Kong experience
    Kelvin K Ng
    Department of Surgery, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, China
    J Hepatobiliary Pancreat Sci 17:548-54. 2010
    ..It is particularly true that LDLT provides the only hope for patients with advanced HCC under the constricting problem of organ shortage...
  19. doi request reprint Tolerance of radiofrequency ablation by patients of hepatocellular carcinoma
    Tan To Cheung
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    J Hepatobiliary Pancreat Surg 16:655-60. 2009
    ..In this study, we analyzed results from use of RFA on HCC patients and determined the lower limit of liver function with which HCC patients can tolerate RFA...
  20. doi request reprint Survival analysis of patients with transplantable recurrent hepatocellular carcinoma: implications for salvage liver transplant
    Kelvin K Ng
    FRCS Glasg, FRCS Edin, FACS, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Rd, Hong Kong
    Arch Surg 143:68-74; discussion 74. 2008
    ..There is no difference in the survival benefit between salvage liver transplant and nontransplant therapies for recurrent hepatocellular carcinoma (HCC)...
  21. ncbi request reprint Duodenopleural fistula formation after percutaneous radiofrequency ablation for recurrent hepatocellular carcinoma
    Fion S Chan
    Centre for the Study of Liver Disease, and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong SAR
    Asian J Surg 30:278-82. 2007
    ..Subsequent uncontrolled infection resulted in empyema thoracis and led to the death of the patient...
  22. ncbi request reprint Selective portal vein clamping for radiofrequency ablation of hepatocellular carcinoma with portal vein invasion
    Kenneth S Chok
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Gastrointest Surg 9:489-93. 2005
    ..Complete tumor ablation was achieved after RFA with left portal vein clamping. He remained disease free both radiologically and biochemically 6 months after the operation...
  23. ncbi request reprint Comparable survival in patients with unresectable hepatocellular carcinoma treated by radiofrequency ablation or transarterial chemoembolization
    Kenneth S Chok
    Departments of Surgery and Radiology, Centre for the Study of Liver Disease, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong
    Arch Surg 141:1231-6. 2006
    ..The survival benefits of radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) are similar for patients with unresectable hepatocellular carcinoma amenable to either treatment...
  24. ncbi request reprint Radiofrequency ablation for hepatocellular carcinoma and metastatic liver tumors: a comparative study
    Danny H F Chow
    Department of Surgery, Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Surg Oncol 94:565-71. 2006
    ..This study compared the effectiveness of radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) and liver metastases...
  25. ncbi request reprint Better survival in female patients with hepatocellular carcinoma: oral contraceptive pills related?
    Chi Ming Lam
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong, Pokfulam, Hong Kong, China
    J Clin Gastroenterol 39:533-9. 2005
    ..Hepatocellular carcinoma (HCC) has an indisputable male predominance. "Gender" as an independent prognostic factor for survival is, however, controversial...
  26. ncbi request reprint Radiofrequency ablation for malignant liver tumor
    Kelvin K Ng
    Department of Surgery, Centre for the Study of Liver Disease, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Surg Oncol 14:41-52. 2005
    ..Nonetheless, more convincing evidence by randomized trials is required for the establishment of a treatment protocol of RFA for patients with malignant liver tumors...
  27. pmc Learning curve for radiofrequency ablation of liver tumors: prospective analysis of initial 100 patients in a tertiary institution
    Ronnie T Poon
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg 239:441-9. 2004
    ..This study aims to evaluate the effect of operator experience on the treatment outcomes of radiofrequency ablation (RFA) for malignant liver tumors...
  28. ncbi request reprint Incomplete ablation after radiofrequency ablation of hepatocellular carcinoma: analysis of risk factors and prognostic factors
    Vincent Wai To Lam
    Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg Oncol 15:782-90. 2008
    ..Complete ablation rates after a single session of radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) vary from 48% to 97%. Limited data are available regarding risk factors and prognostic significance of incomplete ablation...
  29. ncbi request reprint Comparison of systemic responses of radiofrequency ablation, cryotherapy, and surgical resection in a porcine liver model
    Kelvin K Ng
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong, Pokfulamad, Hong Kong, China com
    Ann Surg Oncol 11:650-7. 2004
    ..The degree of systemic response after hepatic radiofrequency ablation (RFA) has not been well investigated...
  30. ncbi request reprint Comparison of percutaneous and surgical approaches for radiofrequency ablation of small and medium hepatocellular carcinoma
    Muhammad Rizwan Khan
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Rd, Hong Kong, China
    Arch Surg 142:1136-43; discussion 1143. 2007
    ..Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) can be performed by percutaneous or surgical approach. Tumor size is an important consideration while deciding the treatment approach...
  31. ncbi request reprint Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database
    Kelvin K Ng
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg Oncol 12:364-73. 2005
    ..This study evaluated the long-term outcome of patients with hepatic resection for large (>5 cm in diameter) or multinodular (more than three nodules) HCC by using a multi-institutional database...
  32. ncbi request reprint Implications for management of Mycobacterium tuberculosis infection in adult-to-adult live donor liver transplantation
    Albert C Y Chan
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Liver Int 27:81-5. 2007
    ..Hepatotoxicity of antituberculous agents and hazardous drug interaction with immunosuppressants may render the graft more susceptible to injury...
  33. ncbi request reprint Management of hepatocellular carcinoma in renal transplant recipients
    Kenneth S Chok
    Department of Surgery, Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Surg Oncol 87:139-42. 2004
    ..The aim of the present study was to review the management and outcome of HCC in renal transplant recipients at a specialized surgical center...
  34. doi request reprint Simplifying hepatic venous outflow reconstruction in sequential living donor liver transplantation
    See Ching Chan
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China
    Liver Transpl 15:1514-8. 2009
    ..Satisfactory venous outflow is reliably achieved because this is the most direct outflow tract...
  35. doi request reprint The outcomes of elderly patients with hepatocellular carcinoma treated with transarterial chemoembolization
    Thomas Yau
    Department of Medicine, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong, China
    Cancer 115:5507-15. 2009
    ..The authors evaluated and compared the treatment outcomes of transarterial chemoembolization (TACE) between young (<or=70 years) and elderly (>70 years) patients at their institute over an 18-year period...
  36. ncbi request reprint Liver transplantation in Asia: past, present and future
    Kelvin K Ng
    Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Ann Acad Med Singapore 38:322-10. 2009
    ..On the whole, future developments to increase the donor pool for the expanding recipient need in Asia would involve transplantation from non-heart beating donor and ABO incompatible transplantation...
  37. doi request reprint Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response
    Thomas Yau
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Cancer 115:428-36. 2009
    ..The current study was a phase 2 open-label study to evaluate the efficacy and tolerability of single-agent sorafenib in the treatment of advanced HCC patients in a hepatitis B-endemic Asian population...
  38. ncbi request reprint Efficacy and tolerability of low-dose thalidomide as first-line systemic treatment of patients with advanced hepatocellular carcinoma
    Thomas Yau
    Department of Medicine, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Oncology 72:67-71. 2007
    ..Thalidomide is an anti-neoplastic agent with anti-angiogenic and other mechanisms of action. We aim to evaluate the efficacy and toxicity of low-dose (100 mg) thalidomide as the first-line treatment of advanced HCC...
  39. ncbi request reprint Management of carcinoma of the gallbladder: a single-institution experience in 16 years
    Siu Yin Chan
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Surg Oncol 97:156-64. 2008
    ..Radical surgery is the only curative treatment for carcinoma of gallbladder. This study aimed to evaluate the outcome of patients with carcinoma of gallbladder managed in a single institution over 16 years...
  40. ncbi request reprint Current treatment strategy for hepatocellular carcinoma
    Kelvin K Ng
    Department of Surgery, Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    Saudi Med J 28:1330-8. 2007
    ..A comprehensive treatment algorithm involving these treatment modalities is mandatory to ensure optimal care of patients with HCC...
  41. ncbi request reprint Hepatic actinomycosis presenting as a liver tumour: case report and literature review
    Alex T Lai
    Centre for the Study of Liver Disease, and Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
    Asian J Surg 27:345-7. 2004
    ..We report the management of a patient with isolated hepatic actinomycosis, and review the clinical features and management of patients with hepatic actinomycosis mimicking liver tumour...