H G Spencer

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. pmc The Selective Maintenance of Allelic Variation Under Generalized Dominance
    Hamish G Spencer
    University of Otago
    G3 (Bethesda) . 2016
  2. pmc Contemporary habitat discontinuity and historic glacial ice drive genetic divergence in Chilean kelp
    Ceridwen I Fraser
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, 340 Great King St, Dunedin 9016, New Zealand
    BMC Evol Biol 10:203. 2010
  3. doi request reprint Effects of genomic imprinting on quantitative traits
    Hamish G Spencer
    National Research Centre for Growth and Development and Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, P O Box 56, Dunedin, 9054, New Zealand
    Genetica 136:285-93. 2009
  4. pmc A chip off the old block: a model for the evolution of genomic imprinting via selection for parental similarity
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, New Zealand
    Genetics 174:931-5. 2006
  5. pmc Population models of genomic imprinting. II. Maternal and fertility selection
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 173:2391-8. 2006
  6. ncbi request reprint Phylogeography of Kauri Snails and their allies from Northland, New Zealand (Mollusca: Gastropoda: Rhytididae: Paryphantinae)
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, PO Box 56, Dunedin, New Zealand
    Mol Phylogenet Evol 38:835-42. 2006
  7. ncbi request reprint Adaptive dynamics, game theory and evolutionary population genetics
    H G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    J Evol Biol 18:1191-3. 2005
  8. pmc Mutation-selection balance at a modifier-of-imprinting locus
    H G Spencer
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 144:361-7. 1996
  9. pmc The effect of genetic conflict on genomic imprinting and modification of expression at a sex-linked locus
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 166:565-79. 2004
  10. pmc Further properties of Gavrilets' one-locus two-allele model of maternal selection
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 164:1689-92. 2003

Detail Information

Publications38

  1. pmc The Selective Maintenance of Allelic Variation Under Generalized Dominance
    Hamish G Spencer
    University of Otago
    G3 (Bethesda) . 2016
    ..We also show that there is a weak tendency for greater weighting of primary effects to evolve over time...
  2. pmc Contemporary habitat discontinuity and historic glacial ice drive genetic divergence in Chilean kelp
    Ceridwen I Fraser
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, 340 Great King St, Dunedin 9016, New Zealand
    BMC Evol Biol 10:203. 2010
    ..antarctica would show relatively little genetic structure, reflecting postglacial recolonisation...
  3. doi request reprint Effects of genomic imprinting on quantitative traits
    Hamish G Spencer
    National Research Centre for Growth and Development and Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, P O Box 56, Dunedin, 9054, New Zealand
    Genetica 136:285-93. 2009
    ..Distinguishing these two types of parent-of-origin effects is not a simple problem and requires further research...
  4. pmc A chip off the old block: a model for the evolution of genomic imprinting via selection for parental similarity
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, New Zealand
    Genetics 174:931-5. 2006
    ..Our modeling also shows that, as with several other hypotheses, polymorphism of imprinting status may evolve under certain circumstances, a feature not predicted by verbal accounts...
  5. pmc Population models of genomic imprinting. II. Maternal and fertility selection
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 173:2391-8. 2006
    ..Imprinting destroys the "sex-symmetry" property of the standard model, dramatically increasing the number of degrees of freedom of the selection parameter set. Cycling in all these models is rare in parameter space...
  6. ncbi request reprint Phylogeography of Kauri Snails and their allies from Northland, New Zealand (Mollusca: Gastropoda: Rhytididae: Paryphantinae)
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, PO Box 56, Dunedin, New Zealand
    Mol Phylogenet Evol 38:835-42. 2006
  7. ncbi request reprint Adaptive dynamics, game theory and evolutionary population genetics
    H G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    J Evol Biol 18:1191-3. 2005
  8. pmc Mutation-selection balance at a modifier-of-imprinting locus
    H G Spencer
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 144:361-7. 1996
    ..Mathematical equivalences between these and nonimprinting models are noted...
  9. pmc The effect of genetic conflict on genomic imprinting and modification of expression at a sex-linked locus
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 166:565-79. 2004
    ..In most of our models stable polymorphism of imprinting status is possible, a behavior not predicted by verbal accounts...
  10. pmc Further properties of Gavrilets' one-locus two-allele model of maternal selection
    Hamish G Spencer
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 164:1689-92. 2003
    ..e., cycling) can occur and (ii) in the special case in which maternal effects and standard viability selection act multiplicatively, maternal selection effectively acts on maternally derived alleles only...
  11. ncbi request reprint Population genetics and evolution of genomic imprinting
    H G Spencer
    Department of Zoology, University of Otago, P O Box 56, Dunedin, New Zealand
    Annu Rev Genet 34:457-477. 2000
    ..And different approaches to modeling the problem of the evolution of imprinting reveal the weakness of several of the apparent predictions of various verbal hypotheses about why imprinting has evolved...
  12. pmc Mutation-selection balance under genomic imprinting at an autosomal locus
    H G Spencer
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 147:281-7. 1997
    ..These models allow us to predict the frequency of a failure to imprint in a normally imprinting system, as well as the frequency of imprinting at a standard nonimprinting locus...
  13. pmc The correlation between relatives on the supposition of genomic imprinting
    Hamish G Spencer
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 161:411-7. 2002
    ..The effects of genomic imprinting will need to be incorporated into quantitative-genetic models of many traits, for example, those concerned with mammalian birthweight...
  14. ncbi request reprint The long and short of it: branch lengths and the problem of placing the New Zealand short-tailed bat, Mystacina
    M Kennedy
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Mol Phylogenet Evol 13:405-16. 1999
    ....
  15. ncbi request reprint The phylogenetic relationships of the shags and cormorants: can sequence data resolve a disagreement between behavior and morphology?
    M Kennedy
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Mol Phylogenet Evol 17:345-59. 2000
    ..Until more taxa are sampled and a fully robust phylogeny is obtained, a conservative approach accepting a single genus, Phalacrocorax, for the shags and cormorants is recommended...
  16. ncbi request reprint Phylogeographical disjunction in abundant high-dispersal littoral gastropods
    J M Waters
    Department of Zoology, University of Otago, PO Box 56, Dunedin, New Zealand
    Mol Ecol 14:2789-802. 2005
    ..Phylogenetic relationships of nine species (four genera) of Neritidae, an almost exclusively tropical gastropod family, are consistent with the hypothesis that southern temperate black nerites comprise a monophyletic radiation...
  17. pmc Population models of genomic imprinting. I. Differential viability in the sexes and the analogy with genetic dominance
    R J Anderson
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 153:1949-58. 1999
    ..Although an imprinting model with sex differences does not formally reduce to a nonimprinting scheme, close theoretical parallels clearly exist...
  18. ncbi request reprint Metazoan parasite species richness and genetic variation among freshwater fish species: cause or consequence?
    R Poulin
    Department of Zoology, University of Otago, P O Box 56, Dunedin, New Zealand
    Int J Parasitol 30:697-703. 2000
    ..Instead, it suggests that parasites may be colonising host species showing low levels of genetic variation with greater success than genetically more variable host species...
  19. doi request reprint Evolutionary consequences of microhabitat: population-genetic structuring in kelp- vs. rock-associated chitons
    R Nikula
    Department of Zoology, Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, PO Box 56, 9054 Dunedin, New Zealand
    Mol Ecol 20:4915-24. 2011
    ..pelliserpentis (R(2) = 0.28) than in S. sinclairi (R(2) = 0.18). These data support the hypothesis that epifaunal taxa can experience enhanced population-genetic connectivity as a result of their rafting ability...
  20. ncbi request reprint Simultaneous polyphenism and cryptic species in an intertidal limpet from New Zealand
    Tomoyuki Nakano
    Department of Earth and Planetary Sciences, Nagoya University, Nagoya 464 8602, Japan
    Mol Phylogenet Evol 45:470-9. 2007
    ..One species exhibits distinctive light-avoiding behaviour, the first known case in which behaviour can be used to separate cryptic species in molluscs...
  21. pmc Evolution of fitnesses and allele frequencies in a population with spatially heterogeneous selection pressures
    Bastiaan Star
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, 9054 Dunedin, New Zealand
    Genetics 177:1743-51. 2007
    ....
  22. pmc Evolution of fitnesses in structured populations with correlated environments
    Bastiaan Star
    Department of Zoology, Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, Dunedin 9054, New Zealand
    Genetics 179:1469-78. 2008
    ....
  23. pmc Frequency-dependent selection and the maintenance of genetic variation: exploring the parameter space of the multiallelic pairwise interaction model
    Meredith V Trotter
    Department of Zoology, Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, Dunedin 9054, New Zealand
    Genetics 176:1729-40. 2007
    ..An example is put forth suggesting possible explanations for multiallelic polymorphisms maintained despite positive FDS on individual alleles...
  24. ncbi request reprint Species assignation amongst morphologically cryptic larval Digenea isolated from New Zealand topshells (Gastropoda: Trochidae)
    Kirsten M Donald
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, P O Box 56, 340 Great King Street, Dunedin, New Zealand
    Parasitol Res 101:433-41. 2007
    ..Amongst this group of digeneans, host information + RFLP provide a rapid, unambiguous method of species assignation that host information + morphological measurements cannot...
  25. pmc Single-locus polymorphism in a heterogeneous two-deme model
    Bastiaan Star
    Department of Zoology, Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, 9054 Dunedin, New Zealand
    Genetics 176:1625-33. 2007
    ..The equilibrium allele-frequency patterns emerging from the two-deme model are more variable and strongly influenced by gene flow...
  26. pmc The evolution of genomic imprinting via variance minimization: an evolutionary genetic model
    Anton E Weisstein
    Department of Zoology, Department of Zoology, University of Otago, Dunedin, New Zealand
    Genetics 165:205-22. 2003
    ..On the basis of this evidence, we conclude that the variance-minimization hypothesis appears less adequate to explain the evolution of genomic imprinting...
  27. ncbi request reprint Phylogenies of the Frigatebirds (Fregatidae) and Tropicbirds (Phaethonidae), two divergent groups of the traditional order Pelecaniformes, inferred from mitochondrial DNA sequences
    Martyn Kennedy
    Division of Environmental and Evolutionary Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    Mol Phylogenet Evol 31:31-8. 2004
    ..The two families are not closely related either to each other, or to any other putative relatives (e.g., pelicans; Pelecanidae)...
  28. pmc Evolutionary genetic models of the ovarian time bomb hypothesis for the evolution of genomic imprinting
    Anton E Weisstein
    Department of Zoology, University of Otago, Dunedin 9001, New Zealand
    Genetics 162:425-39. 2002
    ..g., mouse insulin-like growth factor 2 receptor (Igf2r)]...
  29. ncbi request reprint Host specificity and molecular phylogeny of larval Digenea isolated from New Zealand and Australian topshells (Gastropoda: Trochidae)
    Kirsten M Donald
    Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, P O Box 56, Great King Street, Dunedin, New Zealand
    Int J Parasitol 34:557-68. 2004
    ..Our results shed light on the conditions that may favour switching among intermediate hosts in digeneans, and on the presence/absence of host specificity in these parasites...
  30. pmc Frequency-dependent selection with dominance: a window onto the behavior of the mean fitness
    Marjorie A Asmussen
    Department of Genetics, University of Georgia, Athens, Georgia 30602 7223, USA
    Genetics 167:499-512. 2004
    ..Computer simulations with random initial conditions and fitnesses reveal that the potential decline in mean fitness is not negligible; on average a net decrease occurs 20% of the time and reduces the mean fitness by >17%...
  31. ncbi request reprint Untangling long branches: identifying conflicting phylogenetic signals using spectral analysis, neighbor-net, and consensus networks
    Martyn Kennedy
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Syst Biol 54:620-33. 2005
    ..These results indicate that spectral analysis, Neighbor-Net, and consensus networks offer a powerful approach to detecting and understanding the source of conflicting signals within phylogenetic data...
  32. ncbi request reprint The phylogeny and taxonomy of austral monodontine topshells (Mollusca: Gastropoda: Trochidae), inferred from DNA sequences
    Kirsten M Donald
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, P O Box 56, Dunedin, New Zealand
    Mol Phylogenet Evol 37:474-83. 2005
    ..The Juan Fernandez endemic D. crusoeana (Pilsbry, 1889) is synonymised with D. nigerrima (Gmelin, 1791). We find that morphologically cryptic species are not necessarily close genetically...
  33. ncbi request reprint A census of mammalian imprinting
    Ian M Morison
    Cancer Genetics Laboratory, Department of Biochemistry and National Research Centre for Growth and Development, University of Otago, PO Box 56, Dunedin, New Zealand
    Trends Genet 21:457-65. 2005
    ..Accumulation of functional and comparative data for these genes will improve our understanding of imprinting and its contribution to mammalian evolution...
  34. ncbi request reprint Cladogenesis as the result of long-distance rafting events in South Pacific topshells (Gastropoda, Trochidae)
    Kirsten M Donald
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, New Zealand
    Evolution 59:1701-11. 2005
    ....
  35. pmc Environmental influences during development and their later consequences for health and disease: implications for the interpretation of empirical studies
    Peter D Gluckman
    Liggins Institute, University of Auckland and National Research Centre for Growth and Development, 2 6 Park Avenue, Grafton, Private Bag 92019, Auckland, New Zealand
    Proc Biol Sci 272:671-7. 2005
    ..The paper reviews these concepts and explores ways in which such distinctions may be made in practice...
  36. doi request reprint Predictive adaptive responses in perspective
    Peter D Gluckman
    Trends Endocrinol Metab 19:109-10; author reply 112. 2008
  37. pmc Influence of mom and dad: quantitative genetic models for maternal effects and genomic imprinting
    Anna W Santure
    Allan Wilson Centre for Molecular Ecology and Evolution, Department of Zoology, University of Otago, Dunedin, 9001 New Zealand
    Genetics 173:2297-316. 2006
    ..Thus, an understanding of various forms of parental effects is essential in correctly estimating quantitative genetic variance components...
  38. pmc An asymmetric model of heterozygote advantage at major histocompatibility complex genes: degenerate pathogen recognition and intersection advantage
    Rick J Stoffels
    Department of Zoology, University of Otago, Dunedin 9054, New Zealand
    Genetics 178:1473-89. 2008
    ..Increasing gamma reduces levels of polymorphism considerably. Hence, if intersection advantage is significant for MHC genotypes, then heterozygote advantage may not explain the very high levels of polymorphism observed at MHC genes...