J A Royds

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. pmc Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level
    Donia P Macartney-Coxson
    1Wakefield Gastroenterology Research Institute, Wellington, New Zealand
    BMC Cancer 8:187. 2008
  2. ncbi request reprint p53 promotes adenoviral replication and increases late viral gene expression
    J A Royds
    Department of Pathology, University of Otago, Dunedin, New Zealand
    Oncogene 25:1509-20. 2006
  3. ncbi request reprint p53 and disease: when the guardian angel fails
    J A Royds
    Department of Pathology, University of Otago, Dunedin, New Zealand
    Cell Death Differ 13:1017-26. 2006
  4. pmc Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant
    T L Slatter
    Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Cell Death Dis 6:e1783. 2015
  5. ncbi request reprint Exploitation of cell cycle and cell death controls by adenoviruses: the road to a productive infection
    I Alasdair Russell
    Cell Transformation Group, Department of Pathology, Dunedin School of Medicine, University of Otago, Box 913, Dunedin, New Zealand
    Prog Mol Subcell Biol 36:207-43. 2004
  6. doi request reprint p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors
    T L Slatter
    Department of Pathology, School of Medicine, University of Otago, Dunedin, New Zealand
    Cell Death Differ 17:540-50. 2010
  7. ncbi request reprint Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme
    V Hakin-Smith
    Institute for Cancer Studies, Medical School, Sheffield, UK
    Lancet 361:836-8. 2003
  8. ncbi request reprint Correlation of VEGF production with IL1 alpha and IL6 secretion by human pituitary adenoma cells
    S A Borg
    Hormone and Vascular Group, Academic Unit of Endocrinology, Division of Genomic Medicine, University of Sheffield Medical School, Sheffield S10 2RX, UK
    Eur J Endocrinol 152:293-300. 2005
  9. ncbi request reprint Comparative genomic hybridization and pathological findings in atypical teratoid/rhabdoid tumour of the central nervous system
    S B Wharton
    Academic Unit of Pathology, University of Sheffield, Medical School, Sheffield, UK
    Neuropathol Appl Neurobiol 29:254-61. 2003
  10. ncbi request reprint Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis
    Z E Winters
    Imperial Cancer Research Fund Molecular Oncology Laboratory, University of Oxford Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK
    Eur J Cancer 37:2405-12. 2001

Collaborators

  • A W Braithwaite
  • M Baird
  • H Campbell
  • G Williams
  • R R Reddel
  • T L Slatter
  • M Wilson
  • C Rubio
  • Donia P Macartney-Coxson
  • S A Borg
  • I Alasdair Russell
  • S B Wharton
  • V Hakin-Smith
  • D Speidel
  • N Hung
  • S Bowie
  • Z E Winters
  • C Holzhauer
  • R Mehta
  • P Ganesan
  • Richard S Stubbs
  • Kylie A Hood
  • Serena Rooker
  • David A Hall
  • Anna Wiles
  • Teresa Ward
  • Rod A Lea
  • Hong Jun Shi
  • Rosemary O'Connor
  • R D Battersby
  • T H Jones
  • K E Kerry
  • M J McKay
  • W R Timperley
  • T Carroll
  • W H Wallace
  • D Levy
  • D W Hammond
  • D A Jellinek
  • M Teo
  • C Wardle
  • J W Ironside
  • H Turley
  • A L Harris
  • N C Hunt
  • M J Bradburn
  • C J Norbury

Detail Information

Publications10

  1. pmc Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level
    Donia P Macartney-Coxson
    1Wakefield Gastroenterology Research Institute, Wellington, New Zealand
    BMC Cancer 8:187. 2008
    ..We therefore examined 8p for genes involved in colorectal cancer progression...
  2. ncbi request reprint p53 promotes adenoviral replication and increases late viral gene expression
    J A Royds
    Department of Pathology, University of Otago, Dunedin, New Zealand
    Oncogene 25:1509-20. 2006
    ..These results have implications for the use of Ad mutants that are defective in p53 degradation, such as ONYX-015, as agents for the treatment of cancers...
  3. ncbi request reprint p53 and disease: when the guardian angel fails
    J A Royds
    Department of Pathology, University of Otago, Dunedin, New Zealand
    Cell Death Differ 13:1017-26. 2006
    ..Finally, we outline some evidence that abnormalities in p53 function contribute to the etiology of other non-neoplastic diseases...
  4. pmc Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant
    T L Slatter
    Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Cell Death Dis 6:e1783. 2015
    ..The data suggest that Δ122p53 (and Δ133p53α) could offer some protection against tumors by enhancing the p53 response to stress. ..
  5. ncbi request reprint Exploitation of cell cycle and cell death controls by adenoviruses: the road to a productive infection
    I Alasdair Russell
    Cell Transformation Group, Department of Pathology, Dunedin School of Medicine, University of Otago, Box 913, Dunedin, New Zealand
    Prog Mol Subcell Biol 36:207-43. 2004
  6. doi request reprint p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors
    T L Slatter
    Department of Pathology, School of Medicine, University of Otago, Dunedin, New Zealand
    Cell Death Differ 17:540-50. 2010
    ..We predict that by keeping B-cell populations in check, p53-dependent apoptosis prevents irregular B cells from eventuating in lymphomas...
  7. ncbi request reprint Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme
    V Hakin-Smith
    Institute for Cancer Studies, Medical School, Sheffield, UK
    Lancet 361:836-8. 2003
    ..In patients with non-ALT tumours, telomerase activity did not affect survival (median 287 [199-375] vs 236 [230-242] days, p=0.275). We conclude that ALT is a prognostic indicator for patients with glioblastoma multiforme...
  8. ncbi request reprint Correlation of VEGF production with IL1 alpha and IL6 secretion by human pituitary adenoma cells
    S A Borg
    Hormone and Vascular Group, Academic Unit of Endocrinology, Division of Genomic Medicine, University of Sheffield Medical School, Sheffield S10 2RX, UK
    Eur J Endocrinol 152:293-300. 2005
    ..We have also looked at the relationship of tumour volume and invasive status to VEGF secretion...
  9. ncbi request reprint Comparative genomic hybridization and pathological findings in atypical teratoid/rhabdoid tumour of the central nervous system
    S B Wharton
    Academic Unit of Pathology, University of Sheffield, Medical School, Sheffield, UK
    Neuropathol Appl Neurobiol 29:254-61. 2003
    ....
  10. ncbi request reprint Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis
    Z E Winters
    Imperial Cancer Research Fund Molecular Oncology Laboratory, University of Oxford Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK
    Eur J Cancer 37:2405-12. 2001
    ..Investigation of the subcellular distribution of cell cycle regulatory proteins, particularly p21(WAF1/CIP1), could provide valuable prognostic markers in breast cancer...