Clint Gray

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. pmc Pre-weaning growth hormone treatment reverses hypertension and endothelial dysfunction in adult male offspring of mothers undernourished during pregnancy
    Clint Gray
    Liggins Institute and Gravida, National Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 8:e53505. 2013
  2. pmc Effects of taurine supplementation on hepatic markers of inflammation and lipid metabolism in mothers and offspring in the setting of maternal obesity
    Minglan Li
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 8:e76961. 2013
  3. pmc Pre-weaning growth hormone treatment ameliorates bone marrow macrophage inflammation in adult male rat offspring following maternal undernutrition
    Clare M Reynolds
    Liggins Institute and Gravida, National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 8:e68262. 2013
  4. doi request reprint Maternal supplementation with conjugated linoleic acid in the setting of diet-induced obesity normalises the inflammatory phenotype in mothers and reverses metabolic dysfunction and impaired insulin sensitivity in offspring
    Stephanie A Segovia
    Liggins Institute and Gravida, National Centre for Growth and Development, University of Auckland, Auckland 1023, New Zealand
    J Nutr Biochem 26:1448-57. 2015
  5. pmc Developmental Programming of Nonalcoholic Fatty Liver Disease: The Effect of Early Life Nutrition on Susceptibility and Disease Severity in Later Life
    Minglan Li
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland 1142, New Zealand
    Biomed Res Int 2015:437107. 2015
  6. pmc Early Life Nutrition and Energy Balance Disorders in Offspring in Later Life
    Clare M Reynolds
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland 1142, New Zealand
    Nutrients 7:8090-111. 2015
  7. pmc A maternal high fat diet programmes endothelial function and cardiovascular status in adult male offspring independent of body weight, which is reversed by maternal conjugated linoleic acid (CLA) supplementation
    Clint Gray
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 10:e0115994. 2015
  8. pmc Maternal salt and fat intake causes hypertension and sustained endothelial dysfunction in fetal, weanling and adult male resistance vessels
    Clint Gray
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, New Zealand
    Sci Rep 5:9753. 2015
  9. doi request reprint Conjugated linoleic Acid supplementation during pregnancy and lactation reduces maternal high-fat-diet-induced programming of early-onset puberty and hyperlipidemia in female rat offspring
    Clare M Reynolds
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, New Zealand
    Biol Reprod 92:40. 2015
  10. doi request reprint Preweaning GH Treatment Normalizes Body Growth Trajectory and Reverses Metabolic Dysregulation in Adult Offspring After Maternal Undernutrition
    Minglan Li
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland 1142, New Zealand
    Endocrinology 156:3228-38. 2015

Collaborators

Detail Information

Publications12

  1. pmc Pre-weaning growth hormone treatment reverses hypertension and endothelial dysfunction in adult male offspring of mothers undernourished during pregnancy
    Clint Gray
    Liggins Institute and Gravida, National Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 8:e53505. 2013
    ..These data suggest that developmental cardiovascular programming is potentially reversible by early life GH treatment and that GH can reverse the vascular adaptations resulting from maternal undernutrition...
  2. pmc Effects of taurine supplementation on hepatic markers of inflammation and lipid metabolism in mothers and offspring in the setting of maternal obesity
    Minglan Li
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 8:e76961. 2013
    ..These data suggest that maternal taurine supplementation may ameliorate the adverse effects observed in offspring following a maternal obesogenic diet but these effects are dependent upon prior maternal nutritional background. ..
  3. pmc Pre-weaning growth hormone treatment ameliorates bone marrow macrophage inflammation in adult male rat offspring following maternal undernutrition
    Clare M Reynolds
    Liggins Institute and Gravida, National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 8:e68262. 2013
    ..Furthermore these cells are pre-disposed to pro-inflammatory M1 macrophage phenotype which has wide-reaching and important effects in terms of obesity and metabolic disease. ..
  4. doi request reprint Maternal supplementation with conjugated linoleic acid in the setting of diet-induced obesity normalises the inflammatory phenotype in mothers and reverses metabolic dysfunction and impaired insulin sensitivity in offspring
    Stephanie A Segovia
    Liggins Institute and Gravida, National Centre for Growth and Development, University of Auckland, Auckland 1023, New Zealand
    J Nutr Biochem 26:1448-57. 2015
    ..This demonstrates that there are critical windows of developmental plasticity in which the effects of an adverse early-life environment can be reversed by maternal dietary interventions. ..
  5. pmc Developmental Programming of Nonalcoholic Fatty Liver Disease: The Effect of Early Life Nutrition on Susceptibility and Disease Severity in Later Life
    Minglan Li
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland 1142, New Zealand
    Biomed Res Int 2015:437107. 2015
    ....
  6. pmc Early Life Nutrition and Energy Balance Disorders in Offspring in Later Life
    Clare M Reynolds
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland 1142, New Zealand
    Nutrients 7:8090-111. 2015
    ....
  7. pmc A maternal high fat diet programmes endothelial function and cardiovascular status in adult male offspring independent of body weight, which is reversed by maternal conjugated linoleic acid (CLA) supplementation
    Clint Gray
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland, New Zealand
    PLoS ONE 10:e0115994. 2015
    ....
  8. pmc Maternal salt and fat intake causes hypertension and sustained endothelial dysfunction in fetal, weanling and adult male resistance vessels
    Clint Gray
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, New Zealand
    Sci Rep 5:9753. 2015
    ....
  9. doi request reprint Conjugated linoleic Acid supplementation during pregnancy and lactation reduces maternal high-fat-diet-induced programming of early-onset puberty and hyperlipidemia in female rat offspring
    Clare M Reynolds
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, New Zealand
    Biol Reprod 92:40. 2015
    ....
  10. doi request reprint Preweaning GH Treatment Normalizes Body Growth Trajectory and Reverses Metabolic Dysregulation in Adult Offspring After Maternal Undernutrition
    Minglan Li
    Liggins Institute and Gravida National Centre for Growth and Development, University of Auckland, Auckland 1142, New Zealand
    Endocrinology 156:3228-38. 2015
    ....
  11. doi request reprint Let-7 miRNA profiles are associated with the reversal of left ventricular hypertrophy and hypertension in adult male offspring from mothers undernourished during pregnancy after preweaning growth hormone treatment
    Clint Gray
    Liggins Institute and Gravida, National Centre for Growth and Development, University of Auckland, Auckland, 1023, New Zealand
    Endocrinology 155:4808-17. 2014
    ..Up-regulation of the LET-7 family of miRNAs observed in GH groups may mediate the reversal of cardiac hypertrophy observed in adult offspring males of UN mothers. ..
  12. pmc Maternal obesity, inflammation, and developmental programming
    Stephanie A Segovia
    Liggins Institute and Gravida, National Centre for Growth and Development, University of Auckland, Auckland 1142, New Zealand
    Biomed Res Int 2014:418975. 2014
    ..Use of nutritional anti-inflammatories in pregnancy including omega 3 fatty acids, resveratrol, curcumin, and taurine may provide beneficial intervention strategies to ameliorate maternal obesity-induced programming. ..