Maarten C Morsink

Summary

Publications

  1. doi request reprint Molecular diagnostic analysis of outbreak scenarios
    M C Morsink
    Department of Innovative Molecular Diagnostics, University of Applied Sciences Leiden Hogeschool Leiden, Leiden, The Netherlands
    Biochem Mol Biol Educ 40:112-20. 2012
  2. doi request reprint Teaching neurophysiology, neuropharmacology, and experimental design using animal models of psychiatric and neurological disorders
    Maarten C Morsink
    Department of Biology and Medical Laboratory Research, Leiden University of Applied Science, Zernikedreef 11, Leiden, The Netherlands
    Adv Physiol Educ 33:46-52. 2009
  3. ncbi request reprint Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes
    M C Morsink
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research LACDR, Leiden University Medical Center LUMC, P O Box 9502, 2300 RA, Leiden, The Netherlands
    Brain Res 1150:14-20. 2007
  4. ncbi request reprint The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells
    M C Morsink
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Amsterdam, The Netherlands
    J Neurochem 99:1282-98. 2006
  5. ncbi request reprint Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time
    M C Morsink
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    J Neuroendocrinol 18:239-52. 2006
  6. ncbi request reprint The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates
    Dorine E M Feldker
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden University Medical Center, PO Box 9502, 2300 RA Leiden, The Netherlands
    Brain Res 1089:10-20. 2006
  7. doi request reprint Central corticosteroid actions: Search for gene targets
    Nicole A Datson
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research and Leiden University Medical Center, The Netherlands
    Eur J Pharmacol 583:272-89. 2008
  8. pmc Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate
    Nicole A Datson
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research and Leiden University Medical Center, The Netherlands
    BMC Genomics 8:190. 2007
  9. ncbi request reprint Effect of brief corticosterone administration on SGK1 and RGS4 mRNA expression in rat hippocampus
    Neeltje G van Gemert
    Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands
    Stress 9:165-70. 2006
  10. ncbi request reprint Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression
    N A Datson
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    Eur J Neurosci 20:2541-54. 2004

Detail Information

Publications10

  1. doi request reprint Molecular diagnostic analysis of outbreak scenarios
    M C Morsink
    Department of Innovative Molecular Diagnostics, University of Applied Sciences Leiden Hogeschool Leiden, Leiden, The Netherlands
    Biochem Mol Biol Educ 40:112-20. 2012
    ..Additionally, the assignment was highly appreciated by the students...
  2. doi request reprint Teaching neurophysiology, neuropharmacology, and experimental design using animal models of psychiatric and neurological disorders
    Maarten C Morsink
    Department of Biology and Medical Laboratory Research, Leiden University of Applied Science, Zernikedreef 11, Leiden, The Netherlands
    Adv Physiol Educ 33:46-52. 2009
    ..Hence, the currently developed case studies constitute a very useful tool for teaching neurophysiology, neuropharmacology, and experimental design...
  3. ncbi request reprint Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes
    M C Morsink
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research LACDR, Leiden University Medical Center LUMC, P O Box 9502, 2300 RA, Leiden, The Netherlands
    Brain Res 1150:14-20. 2007
    ..The results are important for understanding the role of GR in pleiotropic control of hippocampal neurotransmission and plasticity, which is characterized by recovery of function transiently raised by excitatory input...
  4. ncbi request reprint The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells
    M C Morsink
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Amsterdam, The Netherlands
    J Neurochem 99:1282-98. 2006
    ..Finally, we identified a number of interesting genes, such as SWI/SNF, synaptosomal-associated protein 25 and certain Rab proteins which may play a role in the effects of glucocorticoids on catecholaminergic neuronal functioning...
  5. ncbi request reprint Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time
    M C Morsink
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    J Neuroendocrinol 18:239-52. 2006
    ..Furthermore, we identified a number of interesting candidate genes which may underlie the glucocorticoid-mediated effects on hippocampal cell function...
  6. ncbi request reprint The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates
    Dorine E M Feldker
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden University Medical Center, PO Box 9502, 2300 RA Leiden, The Netherlands
    Brain Res 1089:10-20. 2006
    ..Together, we hypothesize that reduced NFkappaB signaling and diminished protein biosynthesis form part of the molecular mechanisms by which a chronic psychosocial stressor induces structural alterations in hippocampus of LAL mice...
  7. doi request reprint Central corticosteroid actions: Search for gene targets
    Nicole A Datson
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research and Leiden University Medical Center, The Netherlands
    Eur J Pharmacol 583:272-89. 2008
    ....
  8. pmc Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate
    Nicole A Datson
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research and Leiden University Medical Center, The Netherlands
    BMC Genomics 8:190. 2007
    ..In contrast to the growing interest for the marmoset as an animal model, the molecular tools for genetic analysis are extremely limited...
  9. ncbi request reprint Effect of brief corticosterone administration on SGK1 and RGS4 mRNA expression in rat hippocampus
    Neeltje G van Gemert
    Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands
    Stress 9:165-70. 2006
    ..Strikingly, SGK1 mRNA expression was strongly up-regulated in the corpus callosum. We reject, however, the hypothesis that the effect of corticosterone on 5-HT1A responsiveness is mediated via altered RGS4 or SGK1 mRNA expression...
  10. ncbi request reprint Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression
    N A Datson
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    Eur J Neurosci 20:2541-54. 2004
    ....