Pia Montanucci

Summary

Publications

  1. doi request reprint Treatment of diabetes mellitus with microencapsulated fetal human liver (FH-B-TPN) engineered cells
    Pia Montanucci
    Laboratory for the Study and Transplant of Pancreatic Islets LSTPI, Department of Internal Medicine, University of Perugia, Via Enrico Dal Pozzo, s n c, Perugia 06126, Italy
    Biomaterials 34:4002-12. 2013
  2. doi request reprint The functional performance of microencapsulated human pancreatic islet-derived precursor cells
    Pia Montanucci
    Laboratory for the Study and Transplant of Pancreatic Islets, Department of Internal Medicine, University of Perugia, Perugia, Via Enrico Dal Pozzo, s n c, 06126, Italy
    Biomaterials 32:9254-62. 2011
  3. ncbi request reprint Neonatal pig liver-derived progenitors for insulin-producing cells: an in vitro study
    Leda Racanicchi
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy
    Tissue Eng 13:2923-31. 2007
  4. doi request reprint Restoration of t cell substes of patients with type 1 diabetes mellitus by microencapsulated human umbilical cord Wharton jelly-derived mesenchymal stem cells: An in vitro study
    Pia Montanucci
    Department of Medicine, Section of Cardiovascular, Endocrine and Metabolic Clinical Physiology, Laboratory for Endocrine Cell Transplants and Biohybrid Organs, University of Perugia, Piazzale Gambuli, Perugia, Italy Electronic address
    Clin Immunol 163:34-41. 2016
  5. doi request reprint In vitro-cultured human islet cell monolayers: stemness markers and insulin recovery upon streptozotocin exposure
    Pia Montanucci
    Section of Internal Medicine and Endocrine and Metabolic Sciences Di M I, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Tissue Eng Part A 15:3931-42. 2009
  6. pmc Insights in Behavior of Variably Formulated Alginate-Based Microcapsules for Cell Transplantation
    Pia Montanucci
    Interdisciplinary Laboratory for Endocrine Cell Transplants and Biohybrid Organs, Department of Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via Enrico Dal Pozzo, s n c, 06126 Perugia, Italy
    Biomed Res Int 2015:965804. 2015
  7. pmc Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases
    Giuseppe Basta
    Department of Internal Medicine, Laboratory for the Study and Transplant of Pancreatic Islets, University of Perugia, Perugia, Italy
    Diabetes Care 34:2406-9. 2011
  8. doi request reprint New simple and rapid method for purification of mesenchymal stem cells from the human umbilical cord Wharton jelly
    Pia Montanucci
    Section of Internal Medicine and Endocrine and Metabolic Sciences Di M I, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Tissue Eng Part A 17:2651-61. 2011
  9. doi request reprint In vitro immunomodulatory effects of microencapsulated umbilical cord Wharton jelly-derived mesenchymal stem cells in primary Sjögren's syndrome
    Alessia Alunno
    Rheumatology Unit, Department of Medicine, Laboratory for the Study and Transplant of Pancreatic Islets LSTPI and Department of Internal Medicine, University of Perugia, Perugia, Italy
    Rheumatology (Oxford) 54:163-8. 2015
  10. ncbi request reprint Long-term cultured neonatal porcine islet cell monolayers: a potential tissue source for transplant in diabetes
    Francesca Mancuso
    Department of Internal Medicine Di M I, University of Perugia, Perugia, Italy
    Xenotransplantation 13:289-98. 2006

Collaborators

Detail Information

Publications12

  1. doi request reprint Treatment of diabetes mellitus with microencapsulated fetal human liver (FH-B-TPN) engineered cells
    Pia Montanucci
    Laboratory for the Study and Transplant of Pancreatic Islets LSTPI, Department of Internal Medicine, University of Perugia, Via Enrico Dal Pozzo, s n c, Perugia 06126, Italy
    Biomaterials 34:4002-12. 2013
    ....
  2. doi request reprint The functional performance of microencapsulated human pancreatic islet-derived precursor cells
    Pia Montanucci
    Laboratory for the Study and Transplant of Pancreatic Islets, Department of Internal Medicine, University of Perugia, Perugia, Via Enrico Dal Pozzo, s n c, 06126, Italy
    Biomaterials 32:9254-62. 2011
    ..Upon intraperitoneal graft in NOD/SCID mice we have observed that the microcapsules acted as three-dimensional niches favouring post-transplant hIPC differentiation and acquisition of beta cell-like functional competence...
  3. ncbi request reprint Neonatal pig liver-derived progenitors for insulin-producing cells: an in vitro study
    Leda Racanicchi
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy
    Tissue Eng 13:2923-31. 2007
    ....
  4. doi request reprint Restoration of t cell substes of patients with type 1 diabetes mellitus by microencapsulated human umbilical cord Wharton jelly-derived mesenchymal stem cells: An in vitro study
    Pia Montanucci
    Department of Medicine, Section of Cardiovascular, Endocrine and Metabolic Clinical Physiology, Laboratory for Endocrine Cell Transplants and Biohybrid Organs, University of Perugia, Piazzale Gambuli, Perugia, Italy Electronic address
    Clin Immunol 163:34-41. 2016
    ..CpS-hUCMS restored a correct Treg/Th17 ratio, relevant to the T1D disease process. In summary, we have preliminarily developed a new biohybrid system, associated with immunoregulatory properties, that is ready for in vivo application. ..
  5. doi request reprint In vitro-cultured human islet cell monolayers: stemness markers and insulin recovery upon streptozotocin exposure
    Pia Montanucci
    Section of Internal Medicine and Endocrine and Metabolic Sciences Di M I, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Tissue Eng Part A 15:3931-42. 2009
    ..All together our data preliminarily seem to indicate that CM may generate reconstituted insulin-producing cells likely due to their intrinsic, preexisting stemness properties...
  6. pmc Insights in Behavior of Variably Formulated Alginate-Based Microcapsules for Cell Transplantation
    Pia Montanucci
    Interdisciplinary Laboratory for Endocrine Cell Transplants and Biohybrid Organs, Department of Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via Enrico Dal Pozzo, s n c, 06126 Perugia, Italy
    Biomed Res Int 2015:965804. 2015
    ..However, only the final application which the capsules are destined to will ultimately guide the selection of the ideal, specific gelling divalent cations, since in principle there are no capsules that are better than others. ..
  7. pmc Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases
    Giuseppe Basta
    Department of Internal Medicine, Laboratory for the Study and Transplant of Pancreatic Islets, University of Perugia, Perugia, Italy
    Diabetes Care 34:2406-9. 2011
    ..To assess long-term metabolic and immunological follow-up of microencapsulated human islet allografts in nonimmunosuppressed patients with type 1 diabetes (T1DM)...
  8. doi request reprint New simple and rapid method for purification of mesenchymal stem cells from the human umbilical cord Wharton jelly
    Pia Montanucci
    Section of Internal Medicine and Endocrine and Metabolic Sciences Di M I, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Tissue Eng Part A 17:2651-61. 2011
    ..Moreover, the basal expression of endocrine cell markers makes these cells seemingly suitable for endocrine cell phenotype differentiation. Noteworthy, Activin A induced hUCMS to acquire definitive endoderm cell markers...
  9. doi request reprint In vitro immunomodulatory effects of microencapsulated umbilical cord Wharton jelly-derived mesenchymal stem cells in primary Sjögren's syndrome
    Alessia Alunno
    Rheumatology Unit, Department of Medicine, Laboratory for the Study and Transplant of Pancreatic Islets LSTPI and Department of Internal Medicine, University of Perugia, Perugia, Italy
    Rheumatology (Oxford) 54:163-8. 2015
    ..We aimed to assess the in vitro effects of IFN-γ-pretreated microencapsulated (CpS)-hUCMS on T cells of pSS...
  10. ncbi request reprint Long-term cultured neonatal porcine islet cell monolayers: a potential tissue source for transplant in diabetes
    Francesca Mancuso
    Department of Internal Medicine Di M I, University of Perugia, Perugia, Italy
    Xenotransplantation 13:289-98. 2006
    ....
  11. ncbi request reprint Effect of all trans retinoic acid on lysosomal alpha-D-mannosidase activity in HL-60 cell: correlation with HL-60 cells differentiation
    Leda Racanicchi
    Department of Internal Medicine Di M I, Section of Internal Medicine and Endocrine and Metabolic Sciences, University of Perugia, Via E dal Pozzo, Perugia 06126, Italy
    Mol Cell Biochem 308:17-24. 2008
    ..These observations may directly be linked with the loss of metastatic progession of differentiated HL-60...
  12. doi request reprint Stem cells for pancreatic β-cell replacement in diabetes mellitus: actual perspectives
    Riccardo Calafiore
    Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Perugia, Perugia, Italy
    Curr Opin Organ Transplant 19:162-8. 2014
    ....