Guillermina Ferro-Flores

Summary

Affiliation: Instituto Nacional de Investigaciones Nucleares
Country: Mexico

Publications

  1. ncbi Radiopharmacokinetic and dosimetric parameters of 188Re-lanreotide in athymic mice with induced human cancer tumors
    Eva M Molina-Trinidad
    Departamento de Tecnologia, Biofarmacia, Facultad de Estudios Superiores CuautitlAn, Universidad Nacional Autonoma de Mexico, Av Quetzalcóatl S N, Estado de Mexico 54740, Mexico
    Int J Pharm 310:125-30. 2006
  2. ncbi Preparation and evaluation of 99mTc-EDDA/HYNIC-[Lys 3]-bombesin for imaging gastrin-releasing peptide receptor-positive tumours
    Guillermina Ferro-Flores
    Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, Mexico
    Nucl Med Commun 27:371-6. 2006
  3. doi Targeted imaging of gastrin-releasing peptide receptors with 99mTc-EDDA/HYNIC-[Lys3]-bombesin: biokinetics and dosimetry in women
    Clara L Santos-Cuevas
    Department of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Universidad Autonoma del Estado de Mexico, Department of Nuclear Medicine, Hospital de Oncología del Centro Médico Siglo XXI, IMSS, Mexico City, Mexico
    Nucl Med Commun 29:741-7. 2008
  4. ncbi Preparation, biodistribution, and dosimetry of 188Re-labeled MoAb ior cea1 and its F(ab')2 fragments by avidin-biotin strategy
    G Ferro-Flores
    Departamento de Materiales Radioactivos, Instituto Nacional de Investigaciones Nucleares, Salazar, Mexico
    Nucl Med Biol 26:57-62. 1999
  5. ncbi Preparation and pharmacokinetics of samarium(III)-153-labeled DTPA-bis-biotin. Characterization and theoretical studies of the samarium(III)-152 conjugate
    G Ferro-Flores
    Instituto Nacional de Investigaciones Nucleares, Mexico, Departamento de Materiales Radiactivos, Km 36 5 Carretera Mexico Toluca, C P 52045
    Bioconjug Chem 10:726-34. 1999
  6. ncbi An efficient, reproducible and fast preparation of 188Re-anti-CD20 for the treatment of non-Hodgkin's lymphoma
    Guillermina Ferro-Flores
    Department of Nuclear Materials, Instituto Nacional de Investigaciones Nucleares, Km 36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, CP 52045, Mexico
    Nucl Med Commun 26:793-9. 2005
  7. ncbi Labeling of biotin with [166Dy]Dy/166Ho as a stable in vivo generator system
    G Ferro-Flores
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Km 36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, C P 52045, Mexico
    Int J Pharm 255:129-38. 2003
  8. ncbi In vitro and in vivo assessment of 99mTc-UBI specificity for bacteria
    Guillermina Ferro-Flores
    Instituto Nacional de Investigaciones Nucleares, Mexico, Mexico
    Nucl Med Biol 30:597-603. 2003
  9. ncbi Molecular recognition and stability of 99mTc-UBI 29-41 based on experimental and semiempirical results
    Guillermina Ferro-Flores
    Depto de Materiales Radioactivos, Instituto Nacionale de Investigaciones Nucleares, Gerencia de Aplicaciones Nucleares en Salud, Km36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, CP 52045, Mexico
    Appl Radiat Isot 61:1261-8. 2004
  10. ncbi [166Dy]Dy/166Ho hydroxide macroaggregates: an in vivo generator system for radiation synovectomy
    G Ferro-Flores
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Km 36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, CP 52045, Mexico
    Appl Radiat Isot 61:1227-33. 2004

Collaborators

  • Laura Meléndez-Alafort
  • B Y Croft
  • Jorge Serment-Guerrero
  • Enrique Vallejo
  • Yu-Min Zhang
  • Mary Rusckowski
  • Martha Pedraza-López
  • Donald J Hnatowich
  • J E Villareal-Barajas
  • Luis A Medina
  • F Monroy-Guzman
  • P Morales-Ramirez
  • Clara L Santos-Cuevas
  • Blanca E Ocampo-García
  • Consuelo Arteaga de Murphy
  • Enrique Morales-Avila
  • Blanca Ocampo-García
  • Rocío García-Becerra
  • Luis M De León-Rodríguez
  • Nallely Jiménez-Mancilla
  • David Ordaz-Rosado
  • Liliana Aranda-Lara
  • Clara Santos-Cuevas
  • Flor de M Ramírez
  • Eugenio Torres-García
  • Veronica Medina-García
  • Keila Isaac-Olivé
  • Erika Azorín-Vega
  • Flor de María Ramírez
  • Myrna Luna-Gutiérrez
  • Héctor Mendoza-Nava
  • Luis Correa-González
  • Eva L Rojas-Calderón
  • Marco A Camacho-López
  • Andrei N Mendoza-Sánchez
  • Pablo A Pichardo-Romero
  • P P Surujpaul
  • Alma D Miranda-Olvera
  • Eva M Molina-Trinidad
  • Armando González-Vázquez
  • Eduardo Murphy-Stack
  • Mario E Romero-Piña
  • Miguel A Camacho-López
  • Miguel Camacho-Lopez
  • Nallely P Jiménez-Mancilla
  • Myrna A Luna-Guitiérrez
  • Leobardo M Gómez-Oliván
  • Leobardo Gómez-Oliván
  • Myrna A Luna-Gutiérrez
  • F de M Ramírez
  • C Gutierrez-Wing
  • M A Camacho-Lopez
  • C Arteaga de Murphy
  • B Ocampo-García
  • Helgi Jung-Cook
  • Zohar Gutiérrez-García
  • Rodrigo Muñóz-Olvera
  • Graciela Pérez-Villaseñor
  • Dolores Mino-León
  • Yaneth Díaz-Torres

Detail Information

Publications37

  1. ncbi Radiopharmacokinetic and dosimetric parameters of 188Re-lanreotide in athymic mice with induced human cancer tumors
    Eva M Molina-Trinidad
    Departamento de Tecnologia, Biofarmacia, Facultad de Estudios Superiores CuautitlAn, Universidad Nacional Autonoma de Mexico, Av Quetzalcóatl S N, Estado de Mexico 54740, Mexico
    Int J Pharm 310:125-30. 2006
    ..The estimated tumor absorbed dose was 460 mGy/MBq. Human effective dose was 0.0182 mSv/MBq. Therefore, (188)Re-lanreotide is a good candidate for PRMRT and a clinical trial is being planned in order to acquire individual dosimetric data...
  2. ncbi Preparation and evaluation of 99mTc-EDDA/HYNIC-[Lys 3]-bombesin for imaging gastrin-releasing peptide receptor-positive tumours
    Guillermina Ferro-Flores
    Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, Mexico
    Nucl Med Commun 27:371-6. 2006
    ..The human equivalent is gastrin-releasing peptide (GRP), whose receptors are over-expressed in a variety of malignant tumours...
  3. doi Targeted imaging of gastrin-releasing peptide receptors with 99mTc-EDDA/HYNIC-[Lys3]-bombesin: biokinetics and dosimetry in women
    Clara L Santos-Cuevas
    Department of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Universidad Autonoma del Estado de Mexico, Department of Nuclear Medicine, Hospital de Oncología del Centro Médico Siglo XXI, IMSS, Mexico City, Mexico
    Nucl Med Commun 29:741-7. 2008
    ..Recently, 99mTc-EDDA/HYNIC-[Lys]-bombesin (99mTc-HYNIC-BN) was reported as a radiopharmaceutical with high stability in human serum, specific cell GRP-R binding and rapid cell internalization...
  4. ncbi Preparation, biodistribution, and dosimetry of 188Re-labeled MoAb ior cea1 and its F(ab')2 fragments by avidin-biotin strategy
    G Ferro-Flores
    Departamento de Materiales Radioactivos, Instituto Nacional de Investigaciones Nucleares, Salazar, Mexico
    Nucl Med Biol 26:57-62. 1999
    ..Our results suggest that 188Re-labeled biotinylated MoAb ior ceal and its F(ab')2 fragments prepared by this method are stable complexes in vivo...
  5. ncbi Preparation and pharmacokinetics of samarium(III)-153-labeled DTPA-bis-biotin. Characterization and theoretical studies of the samarium(III)-152 conjugate
    G Ferro-Flores
    Instituto Nacional de Investigaciones Nucleares, Mexico, Departamento de Materiales Radiactivos, Km 36 5 Carretera Mexico Toluca, C P 52045
    Bioconjug Chem 10:726-34. 1999
    ..Accordingly, the coordination sphere of Sm(III) was totally satisfied with nitrogen and oxygen donors; the best coordination number was 9. The conformation geometry of both compounds is presented...
  6. ncbi An efficient, reproducible and fast preparation of 188Re-anti-CD20 for the treatment of non-Hodgkin's lymphoma
    Guillermina Ferro-Flores
    Department of Nuclear Materials, Instituto Nacional de Investigaciones Nucleares, Km 36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, CP 52045, Mexico
    Nucl Med Commun 26:793-9. 2005
    ..Therapies using Y-anti-CD20 or I-anti-CD20 have demonstrated their efficacy in patients with B-cell non-Hodgkin's lymphoma. Re is a radionuclide useful for radioimmunotherapy...
  7. ncbi Labeling of biotin with [166Dy]Dy/166Ho as a stable in vivo generator system
    G Ferro-Flores
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Km 36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, C P 52045, Mexico
    Int J Pharm 255:129-38. 2003
    ..In conclusion, the radiolabeled biotin prepared in this investigation has adequate properties to work as a stable in vivo generator system for targeted radiotherapy...
  8. ncbi In vitro and in vivo assessment of 99mTc-UBI specificity for bacteria
    Guillermina Ferro-Flores
    Instituto Nacional de Investigaciones Nucleares, Mexico, Mexico
    Nucl Med Biol 30:597-603. 2003
    ..08 +/- 0.49 compared to 1.14 +/- 0.45 for (67)Ga-citrate. In conclusion, the in vitro and in vivo results provide evidence that a specific mechanism is responsible of the (99m)Tc-UBI bacterial intracellular accumulation...
  9. ncbi Molecular recognition and stability of 99mTc-UBI 29-41 based on experimental and semiempirical results
    Guillermina Ferro-Flores
    Depto de Materiales Radioactivos, Instituto Nacionale de Investigaciones Nucleares, Gerencia de Aplicaciones Nucleares en Salud, Km36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, CP 52045, Mexico
    Appl Radiat Isot 61:1261-8. 2004
    ..In conclusion, the in vitro specific binding to bacteria and the accumulation at infection sites in humans of 99mTc-labeled UBI could be the result of its high thermodynamic stability, selectivity and stereospecificity...
  10. ncbi [166Dy]Dy/166Ho hydroxide macroaggregates: an in vivo generator system for radiation synovectomy
    G Ferro-Flores
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Km 36 5 Carretera Mexico Toluca, Ocoyoacac, Estado de Mexico, CP 52045, Mexico
    Appl Radiat Isot 61:1227-33. 2004
    ....
  11. doi 99mTc-N2S2-Tat (49-57)-bombesin internalized in nuclei of prostate and breast cancer cells: kinetics, dosimetry and effect on cellular proliferation
    Clara L Santos-Cuevas
    Instituto Nacional de Investigaciones Nucleares, Estado de Mexico, Mexico
    Nucl Med Commun 32:303-13. 2011
    ..A new hybrid radiopharmaceutical of type Tc-N2S2-Tat(49-57)-Lys-BN (Tc-Tat-BN) internalized in cancer cell nuclei could act as an effective system of targeted radiotherapy using Auger and internal conversion electron emissions near DNA...
  12. doi Design, preparation, in vitro and in vivo evaluation of (99m)Tc-N2S2-Tat(49-57)-bombesin: a target-specific hybrid radiopharmaceutical
    Clara L Santos-Cuevas
    Instituto Nacional de Investigaciones Nucleares, Mexico
    Int J Pharm 375:75-83. 2009
    ..05). The tumor-to-muscle radioactivity ratio was 8.5 for (99m)Tc-Tat-BN and 7 for (99m)Tc-BN. Therefore, this hybrid is potentially useful in breast and prostate cancer imaging...
  13. doi Design and biological evaluation of ⁹⁹mTc-N₂S₂-Tat(49-57)-c(RGDyK): a hybrid radiopharmaceutical for tumors expressing α(v)β(3) integrins
    Blanca E Ocampo-García
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Estado de Mexico, Mexico
    Nucl Med Biol 40:481-7. 2013
    ....
  14. ncbi Lys3-bombesin conjugated to 99mTc-labelled gold nanoparticles for in vivo gastrin releasing peptide-receptor imaging
    Andrei N Mendoza-Sánchez
    Instituto Nacional de Investigaciones Nucleares, Estado de Mexico, C P 52750, Mexico
    J Biomed Nanotechnol 6:375-84. 2010
    ....
  15. doi Multimeric system of 99mTc-labeled gold nanoparticles conjugated to c[RGDfK(C)] for molecular imaging of tumor α(v)β(3) expression
    Enrique Morales-Avila
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Estado de México, Mexico
    Bioconjug Chem 22:913-22. 2011
    ..18 ± 0.57% ID/g. Micro-SPECT/CT images showed evident tumor uptake. (99m)Tc-AuNP-RGD demonstrates properties suitable for use as a target-specific agent for molecular imaging of tumor α(V)β(3) expression...
  16. ncbi Biokinetics of (99m)Tc-UBI 29-41 in humans
    Laura Meléndez-Alafort
    Universidad Autónoma el Estado de México, Estado de Mexico, Mexico
    Nucl Med Biol 31:373-9. 2004
    ..All infection positive(99m)Tc-UBI images were in agreement with those obtained with (67)Ga-citrate. The mean radiation absorbed dose calculated was 0.13 mGy/MBq for kidneys and the effective dose was 4.34 x 10(-3)mSv/MBq...
  17. doi Synthesis and evaluation of Lys¹(α,γ-Folate)Lys³(¹⁷⁷Lu-DOTA)-Bombesin(1-14) as a potential theranostic radiopharmaceutical for breast cancer
    Liliana Aranda-Lara
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac 52750, Estado de Mexico, México Facultad de Medicina, Universidad Autonoma del Estado de Mexico, Toluca 50180, Mexico
    Appl Radiat Isot 107:214-9. 2016
    ..9±2.1 Gy. T47D-tumors were clearly visible (Micro-SPECT/CT images). (177)Lu-Folate-BN demonstrated properties suitable as a theranostic radiopharmaceutical...
  18. ncbi Biokinetics and dosimetry of 188Re-anti-CD20 in patients with non-Hodgkin's lymphoma: preliminary experience
    Eugenio Torres-García
    Instituto Nacional de Investigaciones Nucleares, Mexico, D F, Mexico
    Arch Med Res 39:100-9. 2008
    ..Our aim was to establish the biokinetics of (188)Re-anti-CD20 in patients and to evaluate its dosimetry as a target-specific radiopharmaceutical for non-Hodgkin's lymphoma (NHL) radioimmunotherapy...
  19. doi Kit for preparation of multimeric receptor-specific ⁹⁹mTc-radiopharmaceuticals based on gold nanoparticles
    Blanca Ocampo-García
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, Mexico
    Nucl Med Commun 32:1095-104. 2011
    ..The conjugation of peptides to gold nanoparticles (AuNPs) produces biocompatible and stable multimeric systems with target-specific molecular recognition...
  20. ncbi Engineered multifunctional RGD-gold nanoparticles for the detection of tumour-specific alpha(v)beta(3) expression: chemical characterisation and ecotoxicological risk assessment
    Enrique Morales-Avila
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Estado de México 52750, Mexico
    J Biomed Nanotechnol 8:991-9. 2012
    ....
  21. doi A freeze-dried kit formulation for the preparation of Lys(27)(99mTc-EDDA/HYNIC)-Exendin(9-39)/99mTc-EDDA/HYNIC-Tyr3-Octreotide to detect benign and malignant insulinomas
    Veronica Medina-García
    Instituto Nacional de Investigaciones Nucleares, Estado de Mexico, 52750, Mexico Universidad Autónoma del Estado de México, Estado de Mexico, 50180, Mexico
    Nucl Med Biol 42:911-6. 2015
    ..The biodistribution and imaging studies demonstrated properties suitable for its use as a target-specific agent for the simultaneous molecular imaging of GRP-1R- and/or SSTR-positive tumors. ..
  22. doi Multifunctional targeted therapy system based on (99m) Tc/(177) Lu-labeled gold nanoparticles-Tat(49-57)-Lys(3) -bombesin internalized in nuclei of prostate cancer cells
    Nallely Jiménez-Mancilla
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Estado de Mexico, México Facultad de Medicina, Universidad Autonoma del Estado de Mexico, Estado de Mexico, Mexico
    J Labelled Comp Radiopharm 56:663-71. 2013
    ..After treatment with (99m) Tc/(177) Lu-AuNP-Tat-BN, the PC3 cell proliferation was inhibited. The nanosystem exhibited properties suitable for plasmonic photothermal therapy and targeted radiotherapy in the treatment of prostate cancer. ..
  23. ncbi Development of specific radiopharmaceuticals for infection imaging by targeting infectious micro-organisms
    Guillermina Ferro-Flores
    Radiopharmaceuticals Division Departamento de Materiales Radiactivos, Instituto Nacional de Investi gaciones Nucleares, Carretera Mexico Toluca S N, La Marquesa, Ocoyoacac, Mexico
    Curr Pharm Des 18:1098-106. 2012
    ....
  24. doi Pharmacokinetics and dosimetry of 188 Re-pharmaceuticals
    Guillermina Ferro-Flores
    Gerencia de Aplicaciones Nucleares en la Salud, Instituto Nacional de Investigaciones Nucleares, Mexico
    Adv Drug Deliv Rev 60:1389-401. 2008
    ..Research on the labeling of biomolecules with the versatile rhenium-188 has contributed to the development of therapeutics with favorable pharmacokinetic and dosimetric properties for cancer treatment...
  25. doi (99m)Tc-labelled gold nanoparticles capped with HYNIC-peptide/mannose for sentinel lymph node detection
    Blanca E Ocampo-García
    Instituto Nacional de Investigaciones Nucleares, Estado de Mexico, Mexico
    Nucl Med Biol 38:1-11. 2011
    ....
  26. ncbi Theranostic Radiopharmaceuticals Based on Gold Nanoparticles Labeled with (177)Lu and Conjugated to Peptides
    Guillermina Ferro-Flores
    Departamento de Materiales Radiactivos, Instituto Nacional de Investigaciones Nucleares, Carretera México Toluca s n La Marquesa, Ocoyoacac, Estado de Mexico, C P 52750, Mexico
    Curr Radiopharm 8:150-9. 2015
    ....
  27. doi Laser heating of gold nanospheres functionalized with octreotide: in vitro effect on HeLa cell viability
    Héctor Mendoza-Nava
    Instituto Nacional de Investigaciones Nucleares, Estado de Mexico, Mexico
    Photomed Laser Surg 31:17-22. 2013
    ..The aim of this study was to assess the effect of laser heating a well-characterized gold nanoparticle (AuNP)-octreotide system on HeLa cell viability, to evaluate its potential as a suitable agent for plasmonic photothermal therapy...
  28. doi Clinical utility of 99mTc-labeled ubiquicidin 29-41 antimicrobial peptide for the scintigraphic detection of mediastinitis after cardiac surgery
    Enrique Vallejo
    Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, D F, Mexico
    Arch Med Res 39:768-74. 2008
    ..This study was conducted to evaluate the clinical use of (99m)Tc-UBI 29-41 for detection of mediastinitis after cardiac surgery...
  29. ncbi Experimental validation of Monte Carlo depth-dose calculations using radiochromic dye film dosimetry for a beta-gamma 153Sm radionuclide applied to the treatment of rheumatoid arthritis
    J E Villareal-Barajas
    Instituto Nacional de Investigaciones Nucleares, Salazar, Estado de Mexico, Mexico
    Radiat Prot Dosimetry 101:439-43. 2002
    ..The possible contributions to these differences are discussed, as well as their relevance for the application of 153Sm in the treatment of rheumatoid arthritis...
  30. doi Gold nanoparticles conjugated to [Tyr3]octreotide peptide
    P P Surujpaul
    Instituto Nacional de Investigaciones Nucleares, Carretera Mexico Toluca S N, La Marquesa, Ocoyoacac, Estado de México C P 52750, Mexico
    Biophys Chem 138:83-90. 2008
    ..The emission band observed in the near-infrared region (692 nm) opens the possibility for AuNP-TOC use in bioimaging...
  31. ncbi Uptake of 153Sm-DTPA-bis-biotin and 99mTc-DTPA-bis-biotin in rat as-30D-hepatoma cells
    Luis Correa-González
    Servicio de Medicina Nuclear, Hospital de Especialidades, Instituto Mexicano del Seguro Social, Centro Medico Nacional Siglo XXI, Mexico
    Nucl Med Biol 30:135-40. 2003
    ....
  32. ncbi Preparation of (166)Dy/(166)Ho-EDTMP: a potential in vivo generator system for bone marrow ablation
    Martha Pedraza-López
    Instituto Nacional de Ciencias Medicas y Nutricion, Salvador Zubiran, Vasco de Quiroga 15, Mexico D F, 14000 Mexico, Mexico
    Nucl Med Commun 25:615-21. 2004
    ....
  33. ncbi Lys and Arg in UBI: a specific site for a stable Tc-99m complex?
    Laura Meléndez-Alafort
    Universidad Autónoma el Estado de México, Mexico
    Nucl Med Biol 30:605-15. 2003
    ..The calculations show that these groups can form a square pyramid with two water molecules for the Tc cation (dxysp(3)). It will be necessary to isolate and characterize the 99Tc(V)(O)-UBI.(H2O)n complex to confirm these results...
  34. ncbi Synthesis of oxytocin HYNIC derivatives as potential diagnostic agents for breast cancer
    Alma D Miranda-Olvera
    Instituto de Investigaciones Cientificas, Universidad de Guanajuato, Guanajuato, Gto Mexico
    Bioconjug Chem 18:1560-7. 2007
    ..Further biochemical experiments demonstrated that 99mTc-EDDA/HYNIC-Cys1-OT-CONH2 could be used as a potential radiopharmaceutical for breast cancer diagnosis...
  35. ncbi Cytotoxic and genotoxic effect of the [166Dy]Dy/166Ho-EDTMP in vivo generator system in mice
    Martha Pedraza-López
    Departamento de Medicina Nuclear, Instituto Nacional de Ciencias Medicas y Nutricion, Salvador Zubiran, Delegacion Tlalpan, Mexico DF 14000, Mexico
    Nucl Med Biol 31:1079-85. 2004
    ..Bone marrow absorbed dose was 18-23 Gy. [(166)Dy]Dy/(166)Ho-EDTMP induces cytotoxicity, genotoxicity and severe myelosuppression in mice. Potentially, it is a good agent for use in humans...
  36. ncbi Biokinetics and dosimetry in patients of 99mTc-EDDA/HYNIC-Tyr3-octreotide prepared from lyophilized kits
    Armando González-Vázquez
    Departamento de Medicina Nuclear, Hospital Militar, Mexico
    Appl Radiat Isot 64:792-7. 2006
    ..3+/-0.7 in receptor-positive tumors at 1 h. The mean radiation absorbed dose calculated for a study using 740 MBq was 24, 21.5, 5.5 and 1.0 mSv for spleen, kidneys, liver and bone marrow respectively and the effective dose was 4.4 mSv...
  37. ncbi [Current developments in SPECT/CT systems using 99mTc-radiopharmaceuticals]
    Guillermina Ferro-Flores
    Instituto Nacional de Investigaciones Nucleares
    Rev Invest Clin 59:373-81. 2007
    ....